As we enter year two of the pandemic, the way hospitals function now and in the future is forever changed. Photo via Getty Images

The COVID-19 pandemic has had a drastic effect on every industry throughout the world. Additionally, we have all experienced multiple changes to our daily routine such as schools implementing virtual and hybrid learning while reconfiguring classrooms to promote social distancing and fitness studios closing off every other cardio machine and bench.

But no industry has had to pivot and innovate more than health care, which has been ground zero for the pandemic.

The pace of innovation for hospitals has been at breakneck speed — from the evolution of new treatment protocols to the need to reconfigure physical spaces to support an influx of patients while also promoting a healing environment during this unprecedented time.

Hospitals look and feel a lot different today because of significant modifications that have been made to care for patients and limit exposure to the virus. While a number of these modifications occurred under temporary state waivers, some of these changes may be here to stay.

Adding windows and alternative communication options to every room

Hospitals found that every room is valuable during a pandemic. Identifying and converting any available space, including private rooms like offices, break rooms, and conference rooms, was essential to accommodate an influx of patients during a surge. And when dealing with a highly infectious area, it is imperative to maximize staff and physician efforts while also safely minimizing the amount of time that staff members enter and exit rooms.

One way to do this is by adding windows in doors to promote patient visibility. This increased visibility can improve patient safety while conserving critical personal protective equipment. However, a down side to limiting the amount of times staff members enter and exit rooms is reduced valuable communication opportunities, which is why alternative mechanisms to communicate with patients must be in place in addition to increased visibility.

Implementing additional negative pressure capabilities

Like adding windows to every patient door, negative pressure rooms exist to keep non-contaminated areas free of airborne pathogens. In a negative pressure room, the air in the room is pulled into a room instead of being pushed out of a room, which is very effective in preventing airborne contaminants from escaping the room and infecting other people. But hospitals are not traditionally built with significant numbers of negative pressure rooms as demand for these types of rooms has historically been low.

In addition, the traditional way to design a facility is to spread negative pressure rooms throughout the hospital instead of consolidating them onto specific units. Although not required for COVID-19 patients, negative pressure rooms are helpful in ensuring maximum capabilities within different zones. In instances where negative pressure rooms could not be created, HEPA filters can still be used to "scrub" the air.

Converting anesthesia machines to ventilators

Anesthesia machines are capable of providing life-sustaining mechanical ventilation to patients with respiratory failure from diseases like COVID-19. They are used for this purpose every day in the operating room. Although they are not recommended for long-term ventilator needs, anesthesia ventilators can be modified to provide ventilatory support and are an obvious first-line backup when there are not sufficient ICU ventilators to meet patient care needs.

Building barriers to increase the safety of care

Plexiglass barriers have become a common sight in daily life including the front desks at hospitals. However, hospitals have taken it a step further and have either built or sourced equipment such as intubation boxes, which can be used during the intubation process, which consists of placing a breathing tube into a patient's airway and then connecting it to a ventilator or anesthesia machine if the patient is having surgery. Intubations are often done by an anesthesiologist, intensive care or emergency room provider; however, traditionally we had not often dealt with highly-contagious patients, so providing a higher level of protection is an important step in the containment of this type of virus.

The way healthcare providers enter and exit a COVID patient's room is as important as the proper use of PPE. In a pre-pandemic world, hospitals didn't specifically create spaces or areas within patient floors for staff to remove and discard their PPE and there wasn't any visible signage warning them that they were about to enter or leave a high-risk area. Many hospitals across the country have implemented color-coded zones within their COVID floors to caution staff of the type of precautions they should be taking at any given time. The creation of zones helps to protect staff and reduce contamination opportunities within the unit itself. Red, yellow and green zones using visual markers can be created to help provide staff designated areas that certain processes must be followed such as where PPE must be worn, where it can be donned and doffed and where PPE should not be worn.

Managing complex logistical challenges

Hospitals have been challenged with having to continue to provide uninterrupted care for COVID and non-COVID patients during the pandemic, while also handling, storing and administering vaccines. Hospitals have been at the forefront of the vaccine distribution system, working closely with state and federal officials to distribute vaccines on a large scale and reach the underserved populations that were hit hardest by COVID-19. For example, Baylor St. Luke's chose Texas Southern University, located within the Third Ward of Houston, as a vaccine site to reach communities of color and leverage its accessible location and the school's pharmacy students and faculty. And more recently, the hospital worked with Rice University to administer vaccines at its football stadium, a large venue that can be accessed easily through public transportation. Having these offsite venues with ample space has helped alleviate the space burden on hospitals during the vaccination efforts. Non-traditional healthcare delivery locations like these allow health care providers to administer more doses, closer to targeted communities than would be possible at a single hospital.

As we enter year two of the pandemic, the way hospitals function now and in the future is forever changed. Hospitals continue to learn and adapt during the COVID-19 pandemic, and in case of another pandemic, hospitals are better equipped to quickly pivot to provide care for a surge of patients and to assist in the recovery efforts.

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Liz Youngblood is president of Baylor St. Luke's Medical Center and senior vice president and COO of St. Luke's Health.

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Houston robotics co. closes series B after year of growth

money moves

Houston- and Boston-based Square Robot Inc. closed a series B round of funding last month.

The advanced submersible robotics company raised $13 million, according to Tracxn.com, and says it will put the funds toward international expansion.

"This Series B round, our largest to date, enables us to accelerate our growth plans and meet the surging global demand for our services,” David Lamont, CEO, said in a statement.

The company aims to establish a permanent presence in Europe and the Middle East and grow its delivery services to reach four more countries and one new continent in Q1 2025.

Additionally, Square Robot plans to release a new robot early next year. The robot is expected to be able to operate in extreme temperatures up to 60 C. The company will also introduce its first AI-enabled tools to improve data collection.

Square Robot launched its Houston office in 2019. Its autonomous, submersible robots are used for storage tank inspections and eliminate the need for humans to enter dangerous and toxic environments.

The company was one of the first group of finalists for the Houston Innovation Awards' Scaleup of the Year, which honors a Bayou City company that's seen impressive growth in 2024. Click here to read more about the company's growth.

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This article originally ran on EnergyCapital.

Show me the money: Top Houston innovation grant and gift news of 2024

year in review

Editor's note: As the year comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. Money means a lot to startups and other innovative entities, and while startups are usually scouting venture capital investors, grants and donations are key too. These are the most-read news articles about grants and gifts — be sure to click through to read the full story.

Rice researchers secure $35M federal grant to advance medical device technology

Rice’s Biotech Launch Pad will lead the effort to commercialize the device. Photo courtesy Rice University

Rice University has secured part of a nearly $35 million federal grant aimed at commercializing a bioelectric implant for treatment of type 2 diabetes and obesity.

The federal Advanced Research Projects Agency for Health awarded the $34.9 million grant to Rice and several other universities.

Rice’s Biotech Launch Pad will lead the effort to commercialize the self-contained, implantable Rx On-site Generation Using Electronics (ROGUE) device. ROGUE houses cells that are engineered to produce type 2 diabetes and obesity therapies in response to patients’ needs. Continue reading.

Houston health care institutions receive $22M to attract top recruits

The grants, which are between $2 million to $6 million each, are earmarked for recruitment of prominent researchers. Photo via Getty Images

Houston’s Baylor College of Medicine has received a total of $12 million in grants from the Cancer Prevention & Research Institute of Texas to attract two prominent researchers.

The two grants, which are $6 million each, are earmarked for recruitment of Thomas Milner and Radek Skoda. The Cancer Prevention & Research Institute of Texas (CPRIT) announced the grants May 14.

Milner, an expert in photomedicine for surgery and diagnostics, is a professor of surgery and biomedical engineering at the Beckman Laser Institute & Medical Clinic at the University of California, Irvine and the university’s Chao Family Comprehensive Cancer Center. Continue reading.

New report ranks Houston top market for life sciences

Houston lands in the No. 7 spot for growth in the granting of degrees in biological and biomedical sciences. Photo by Natalie Harms/InnovationMap

Thanks in large part to producing hundreds of college-trained professionals, Houston’s life sciences industry ranks among the top U.S. markets for talent in 2024.

In a report published by commercial real estate services company CBRE, Houston lands in the No. 7 spot for growth in the granting of degrees in biological and biomedical sciences. From 2017 to 2022, Houston notched a growth rate of 32.4 percent in this category.

In 2022, the University of Houston led the higher education pack in the region, graduating 746 people with a bachelor’s degree or above in biological or biomedical sciences, according to the report. Continue reading.

Texas organization grants $68.5M to Houston institutions for recruitment, research

Several Houston organizations have received millions from the Cancer Prevention and Research Institute of Texas. Photo via tmc.edu

Three prominent institutions in Houston will be able to snag a trio of high-profile cancer researchers thanks to $12 million in new funding from the Cancer Prevention and Research Institute of Texas.

The biggest recruitment award — $6 million — went to the University of Texas MD Anderson Center to lure researcher Xiling Shen away from the Terasaki Institute for Biomedical Innovation in Los Angeles.

Shen is chief scientific officer at the nonprofit Terasaki Institute. His lab there studies precision medicine, including treatments for cancer, from a “systems biology perspective.” Continue reading.

Houston health care institution secures $100M for expansion, shares renderings

Baylor College of Medicine's Lillie and Roy Cullen Tower is set to open in 2026. Rendering courtesy of SLAM Architecture

Baylor College of Medicine has collected $100 million toward its $150 million fundraising goal for the college’s planned Lillie and Roy Cullen Tower.

The $100 million in gifts include:

  • A total of $30 million from The Cullen Foundation, The Cullen Trust for Health Care, and The Cullen Trust for Higher Education.
  • $12 million from the DeBakey Medical Foundation
  • $10 million from the Huffington Foundation
  • More than $45 million from members of Baylor’s Board of Trustees and other community donors, including the M.D. Anderson Foundation, the Albert and Margaret Alkek Foundation, and The Elkins Foundation.

“The Cullen Trust for Health Care is very honored to support this building along with The Cullen Foundation and The Cullen Trust for Higher Education,” Cullen Geiselman Muse, chair of The Cullen Trust for Health Care, says in a news release. “We cannot wait to see what new beginnings will come from inside the Lillie and Roy Cullen Tower.” Continue reading.

TMC launches cancer-focused partnership with Japan

global collaboration

Houston's Texas Medical Center announced the launch of its new TMC Japan BioBridge and Japan-Accelerator Cancer Therapeutics and Medical Devices, or JACT, this month.

The strategic partnership between Japan-based Mitsui Fudosan Co. Ltd. and the National Cancer Center will focus on advancing cancer treatments and providing a pathway for Japanese innovators to expand in the U.S. market. A delegation from TMC recently visited Tokyo, and William F. McKeon, president and CEO of TMC, signed the TMC Japan BioBridge Memorandum of Understanding with Takeshi Ozane, general manager of Mitsui Fudosan, and Hitoshi Nakagama, president of the National Cancer Center of Japan.

“The launch of TMC Japan BioBridge is a vital step forward in connecting two global leaders in healthcare innovation,” McKeon says in a statement. “Japan’s leadership has demonstrated an impressive commitment to advance medical cures and life sciences technologies and through this partnership, we are opening necessary doors for Japanese researchers and innovators to access the US market and collaborate with our TMC ecosystem. Together, we aim to accelerate critical breakthroughs to make a difference for patients all around the world.”

The new JACT will offer cancer-treatment companies a structured process to prepare for a U.S. expansion and will allow for meetings with pharmaceutical companies, hospital systems and investors and provide insights on U.S. regulatory approvals. It'll focus on three key areas, according to the statement:

  1. Milestone development and financial planning
  2. Clinical and regulatory expertise
  3. Strategic partnerships and market insights

“This TMC Japan BioBridge and JACT Program will enable us to promote the advancement of start-up companies aiming to commercialize innovative medical technologies originating in Japan into the U.S." Nakagama says in a statement. "We also hope this collaboration will not be limited to our (Japan Agency for Medical Research and Development)-supported project, but will lead to further cooperation between TMC, NCC, and other Japanese institutions in various fields.”

This is the sixth international strategic partnership for the TMC. It launched its first BioBridge, which focus on partnerships to support international healthcare companies preparing for U.S. expansion, with the Health Informatics Society of Australia in 2016. It also has BioBridge partnerships with the Netherlands, Ireland, Denmark and the United Kingdom.