A new exhibit taps into tech to bring to life the work of Vincent Van Gogh. Photo by Michael Brosilow

A traveling art immersion experience has officially opened its doors in Houston. The tech-enabled show picked a particularly innovative spot, too.

The new "Immersive Van Gogh Exhibit Houston," opened Thursday, October 14, at Lighthouse Artspace Houston, a converted, 16,500-square-foot warehouse space (1314 Brittmore Rd.) directly next to The Cannon's West Houston innovation and entrepreneurial hub in The Founders District. The show has sold more than 3 million tickets sold nationwide, the show has outsold Taylor Swift.

Not to be confused with the current Van Gogh interactive offering, this stunning — and original — show animates some of the most iconic works for Van Gogh, who is considered one of humanity's most important and notable artists.

Equally a star player in the production is the music, some by Italian composer Luca Longobardi, along with a classic from Edith Piaf, and even a tune from Radiohead lead singer Thom Yorke.

Masterpieces come alive via some 60,600 frames of video, totaling 90,000,000 pixels and more than 500,000 cubic feet of projections. But as anyone who's studied the master's works can attest, that detail is necessary to truly capture his creations.

Giant walls dance with images of workers in fields, which then wipe to floral settings, or memorable imagery from Van Gogh's instantly recognizable pieces such as Mangeurs de Pommes de Terre (The Potato Eaters, 1885), Les Tournesols (Sunflowers,1888), La Chambre à coucher (The Bedroom, 1889), and the unforgettable Nuit étoilée (Starry Night, 1889).

Even the floor — lined with circles to stand or sit on for social distancing — is a piece of art. Visitors can stroll (highly recommended), space permitting, or sit, awash in Van Gogh's dreamscape.

"It's really interesting you comment that this could be Van Gogh's dream," Vito Iaia, co-founder of Impact Museums and the event's co-producer, tells CultureMap. "This is what Massimiliano Siccardi, the protection artist who created the work you see on the walls, believes went through Van Gogh's head — right before he died."

Part art exhibit, part animated film, "Immersive Van Gogh Exhibit Houston" marries the work of three different artists: Van Gogh (of course), aforementioned projection artist Siccardi, and Rowan Doyle, the creative director who created the scenic elements surrounding the venue.

Those scenic elements include:

  • Sunflower pickup truck: A vintage Ford truck, parked outside the venue, gets a splash of sunflower yellow.
  • Van Gogh Chapel: Meant to be a love letter to Houston and specifically Rothko Chapel, this design is meant to be a contemplative space before entering the main gallery.
  • Van Gogh Timeline: As the name implies, this installation features pivotal moments of Van Gogh's career, with symbols harking to his short life.
  • Texas sunflower sign: Sunflowers dot the Texas state display, perfect for IG selfies.

A bar and gift shop also add to the experience.

At once stirring, playful, and poignant — even emotional — the experience is fitting for now, despite the artwork dating back to the late 1800s.

"People ask why Massimiliano chose Van Gogh right now," says Iaia. "And part of the answer is there's probably no better time to tell Van Gogh's story than right now. This is a reflection of what he went through as a troubled soul and the struggles people are going through today."

But it's not all dark. "The bright side is, this is a great way to remember his work. The reception has been amazing. It's giving him a new life."

Prepare for a serene, honest moment, but don't be surprised to be affected — especially with the final imagery. "People are driven to joys, or tears, or thought," says Iaia. I had someone come out and say, 'I just saw God.'"

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This article originally ran on CultureMap.

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Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.

Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”