3 Houston innovators to know this week

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This week's roundup of Houston innovators includes Allie Danziger of Ampersand Professionals, Jane Stricker of the Greater Houston Partnership, and Summer Reeves of Accenture's Houston Fjord Studio. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from energy to design innovation — recently making headlines in Houston innovation.

Allie Danziger, co-founder and CEO of Ampersand Professionals

The ongoing trend of businesses struggling to onboard new employees is likely going to continue through the new year. Allie Danziger shares what you need to know. Photo courtesy of Ampersand

The Great Resignation is among us, and companies need to respond accordingly, Allie Danziger, CEO and co-founder of Ampersand Professionals, writes in her guest column for InnovationMap.

"It has been particularly difficult to hire and retain Gen Z employees, the newest generation in the workforce, as we navigate the expectations of these employees, as compared to past generations," she writes. "Fortunately, businesses can bounce back from 'The Great Resignation' or protect themselves before they experience a similar mass exodus by taking the time to understand employees' preferences and motivations, and make a few small changes accordingly."

Danziger shares four tips with hiring and retaining talent in this challenging time. Click here to read more.

Jane Stricker, executive director of the Houston Energy Transition Initiative at the GHP

The former BP executive will lead Houston's role in the energy transition as the executive director of the Houston Energy Transition Initiative, a brand new position at the Greater Houston Partnership. Photo courtesy of GHP

Jane Stricker, a longtime Houston-based executive at oil and gas giant BP, has been tapped to be the executive director of the Houston Energy Transition Initiative and senior vice president of energy transition.

The Greater Houston Partnership unveiled HETI in June. As the partnership explained then, HETI "aims to drive sustainable and equitable economic growth in the Greater Houston region through a portfolio of technology, policy, and market initiatives that scale and export solutions for realizing a low-carbon energy world."

"This is an exciting time for Houston and our energy ecosystem as we focus our efforts on leading the global energy transition," Stricker says. "The challenge of our lifetime is addressing this dual challenge of meeting increased global energy demand while confronting global climate change. Houston is known for solving problems that matter. I believe through innovation, collaboration, and focus, our region can lead the way and deliver solutions that change the world." Click here to read more.

Summer Reeves, director of Accenture's Houston Fjord studio

Summer Reeves says Houston is changing for the better when it comes to attracting design talent. Photo courtesy of Accenture

The winds have changed in Houston when it comes to attracting design talent, Summer Reeves — the director of Accenture's Houston Fjord studio — says on last week's episode of the Houston Innovators Podcast. Reeves is currently responsible for growing the team of Accenture's new Houston Fjord studio. She say she's excited for the way the design industry in Houston has developed. It's been second chair to Austin on the Texas landscape, but that's changing.

"There's a reason why Accenture is building a Fjord studio here in Houston — and now, versus in the past," Reeves says.

She describes Austin employers overly competitive for designers — making it hard to attract and retain design talent. This has caused a wave of designers coming to Houston. She's also seeing Houston employers — mostly in the energy industry — shift their thinking in hiring these types of positions. Click here to read more and stream the episode.

Summer Reeves, the director of Accenture's Houston Fjord studio, says Houston is changing for the better when it comes to attracting design talent. Photo courtesy of Accenture

This expert shares why Houston has a bright future as a design-led innovation city

Houston innovators podcast episode 110

When you think of design in terms of the role it plays in innovation and technology, you might picture a graphic designer or maybe one step in a product's path to market. But for Summer Reeves, design is an integral part of the entire innovation process.

"When people think about design, they think about visual design — UX/UI digital products," Reeves says on this week's episode of the Houston Innovators Podcast. "But what we do from a service design or, what I like to say, a holistic design approach is very different."

Reeves is the director of the Houston Fjord studio — which operates under Accenture Interactive. She's currently standing up the new studio in Houston, which has iterations across the world from Austin and New York to Barcelona and Singapore. The new studio in Houston will help Accenture clients think through the design of their solutions, rather than jump the gun on deploying a technology.

"We want to be a design-led company," Reeves says. "Fjord is what I call the tip of the spear of what we do."

Fjord's design team focus on understanding the root cause of the problem, who's impacted, and what the scale of the solution should be. On the podcast, she gives the example of a coffee shop that wants a mobile app to engage with customers. Reeves says rather than just creating the app, Fjord would look at what the customer wants via surveys and observations.

"It's human nature to jump to solutioning," she says, "but we need to do research to make sure that's the right call."

Reeves is currently responsible for growing the team of the studio — something not too unfamiliar to her. She was instrumental in setting up Accenture's Houston Innovation Center. She say she's excited for the way the design industry in Houston has developed. It's been second chair to Austin on the Texas landscape, but that's changing.

"There's a reason why Accenture is building a Fjord studio here in Houston — and now, versus in the past," Reeves says.

Reeves shares more on the intersection between design and innovation — as well as how COVID-19 affected consulting — on the podcast. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

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New Houston biotech co. developing capsules for hard-to-treat tumors

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Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

$1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
$922 million for the University of Houston System
$167 million for Texas Southern University
$10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
Created the Lake Houston Dredging and Maintenance District
Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

Microsoft partners with Rice University's OpenStax on AI teaching tool

group project

Rice University’s OpenStax and Microsoft are partnering to integrate the nonprofit’s content with the tech giant’s AI innovation, known as Learning Zone.

“At OpenStax, our mission is to make an amazing education accessible to all,” Richard G. Baraniuk, founder and director of OpenStax, said in a news release. “That’s why we’re excited to integrate our trustworthy, peer-reviewed content with Microsoft’s AI technology through the Microsoft Learning Zone. Together, we aim to help more instructors and their students access engaging, effective learning experiences in new and dynamic ways. We also share a strong commitment to the thoughtful and responsible application of AI to better ensure all learners can succeed.”

OpenStax is a provider of affordable instructional technologies and is also one of the world’s largest publishers of open educational resources (OER).

Microsoft Learning Zone promises to provide educators and students with “responsible AI technology and peer-reviewed educational content to support learning” on Microsoft Copilot+ PCs. Microsoft Learning Zone works by utilizing on-device AI to generate interactive lessons for students, and its integration with OpenStax content means educators can rely on OpenStax’s digital library of 80 openly licensed titles.

The goal is for educators to create effective and engaging learning experiences safely, thereby bypassing the need to source and vet content independently. Included is a library of ready-to-use lessons, opportunity for immediate feedback and differentiated learning. Educators will maintain control of instructional content and pedagogical strategies and will be able to update or edit lessons or activities prior to sharing them with students.

Other tools included in the Microsoft Learning Zone are additional languages, reading coaching, public speaking help, math and reading progress, and a partnership with the online quiz platform Kahoot!

OpenStax resources have been reported as used across 153 countries, and this current collaboration combines the power and potential of responsible AI usage in education with content that has been utilized by 13,569 K-12 schools and 71 percent of U.S. colleges and universities, according to Rice.

“Through our partnership with OpenStax, we’re combining the power of on-device AI in Copilot+ PCs with OpenStax’s trusted and diverse peer-reviewed content to help educators quickly create high-quality, personalized, engaging lessons,” Deirdre Quarnstrom, vice president of Microsoft Education, added in the news release. “We’re excited about how this collaboration will empower classrooms globally.”

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