Small businesses and startups are likely to hurt — and hurt bad — from COVID-19's affect on the economy. Here are some resources to get support. Photo by Hero Images

It's a trying time for the world, and Houston small businesses and startups have been put in a difficult spot. From having to work remotely or being forced to close or scale back operations due to mandates from the government, entrepreneurs are having to figure out their new normals.

However, organizations have leapt at the chance to help their fellow Houstonians, and a number of resources have appeared to provide aid to startups, from advice and resources to grants.

Editor's note: This article originally ran March 25, 2020, but has been updated and republished with more resources.

The Cannon's CERT Program

The Cannon released information about their Cannon Emergency Response Team Program, and Houston startups can apply online. The multi-week program is intended to provide aid and support for startups and small businesses experiencing a crisis caused by external forces — namely COVID-19 and its repercussions, but also natural disasters, market disruption, legislative actions, civil unrest, fraud, or theft.

Click here to apply and learn more.

The Ion's resource center

The Ion has also rounded up resources for its members and the greater Houston innovation ecosystem. It's available online, and has everything from links to national and local resources and financial assistance information to virtual events.

"While we all try and adjust to this new way of life, The Ion will continue to be a resource to our entrepreneurial community the best way we know how, by connecting our community and providing you with opportunities that you need to be resilient during these unstable times. ... We hope this page serves you well and we promise to keep you all up to date on everything innovation taking place in our community," writes Gaby Rowe, executive director of The Ion.

Rowe has also started a video series of interviews with Houston startups — the videos are also available on the webpage.

Click here to access the resource center.

Houston Exponential's virtual event calendar

Houston Exponential worked quickly to turn their online calendar featuring events across the innovation ecosystem in Houston to helpful virtual events. Anyone can submit an event for consideration.

Click here to find the calendar.

To find InnovationMap's curated list of events for April, click here.

The GHP's Greater Houston Business Recovery Center

The Greater Houston Partnership has released a one-stop shop for business help for companies large and small. The amalgamation combines several national and local options, including relevant information about the Coronavirus Aid, Relief, and Economic Security (CARES) Act.

"We know many Houston companies are hurting and do not have the resources to sustain themselves for weeks without help," said Bob Harvey, president and CEO of the Partnership. "The funds provided through the CARES Act are essential to ensure Houston businesses can meet payroll and cover other expenses during this difficult time. "

Click here to visit the Greater Houston Business Recovery Center page.

Fat Finger's procedure app

In an effort to help businesses organize their response, Houston-based tech company Fat Finger has released a procedure app that is available for free. It offers employee agreements, important protocol checklists, and more.

"Our intention is to help teams of all types operate as safe and effective as possible to overcome what we are all going through," writes James McDonough, founder and CEO of the company.

Click here to learn more about the app here.

Houston PR firm to offer free services

Houston-based Paige PR is offering up $5,000 worth of its services to help out a company affected by COVID-19., which includes media relations, influencer relations, media training, employee communication, content development, social media management, corporate event planning, campaign measurement, brand management, community engagement and crisis communication, according to a news release.

"Paige PR's mission is to empower and help businesses tell their unique stories and amplify their messages," says Paige Donnell, Paige PR's founder and CEO, in the release. "Our team wanted to give back and honor a company making a positive difference, despite these uncertain times. Now is not the time to halt your company's marketing and communication efforts. However, we understand that this may be the only option for some businesses. We're in this together, and all of us at Paige PR look forward to offering our services free of charge to one deserving company."

Click here to learn more and enter your company.

Gener8tor's free 1-week response program

Just like most accelerator programs, cohort schedules and plans have been affected by COVID-19, but one new-to-Houston program is making some lemonade out of the lemons they were served. Gener8tor, along with the Downtown Redevelopment Authority, announced a partnership for one week of virtual programming for small businesses affected by the COVID-19 outbreak. It's free and an extension of the gBETA program, which launched in Houston in January.

Interested entrepreneurs must apply to be enrolled by Friday, May 27. The week of virtual assistence begins March 30 and goes until April 3. Participants will have access to virtual office hours with experts.

"We have seen firsthand the impact that entrepreneurs have on a community and we hope to call on our network of mentors, investors, and partners to support these new Emergency Response Programs," says Joe Kirgues, Co-Founder of gener8tor, in a news release.

Click here to learn more and sign up.

Hello Alice's business center

Houston-based Hello Alice is a great digital resource for startups locally and beyond. The organization recently announced its grant program that will focus on funding minority-founded startups and quickly snapped into action to create a COVID-19 Business Center free for entrepreneurs to use.

Alice is offering emergency grants to businesses affected by COVID-19 and has also gathered other resources like mental health information, tips for running a remote workforce, and more.

Click here to access the business center.

The Small Business Administration's webinars and disaster loans

Startups, nonprofits, and small businesses can apply for an Economic Injury Disaster Loans for up to $2 million. For small businesses, the interest rate is 3.75 percent, and for nonprofits, the interest rate is 2.75 percent. The SBA's Houston chapter is available for help as well.

Click here to learn more about the EIDLs.

Impact Hub Houston's comprehensive list

If this list here isn't exhaustive enough, Impact Hub Houston has gone the extra mile on their blog, creating a comprehensive and updated list of resources for small businesses and startups, as well as for people in general. There is everything from information on small business financial help and online education to tips for parents and health-related resources.

Click here to access the guide.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Axiom Space expands executive team with two C-suite hires

new leaders

Fresh off officially making Texas its legal headquarters, Axiom Space has named two new C-level executives.

The Houston-based spacetech company, which is developing the first commercial space station, announced earlier this month that it had appointed Zach Gitomer as its new chief financial officer and Erick Wegerer as chief information officer.

Gitomer served as vice president of investor relations and capital markets for Axiom from March to June of this year. Before joining Axiom, he held various leadership roles at Bank of America, Merrill Lynch, and Citi, where he supported technology and growth companies, according to Axiom.

"Building era-defining space infrastructure and pioneering the orbital economy is a complex endeavor that requires not just an audacious vision and stellar engineering talent, but the financial infrastructure, discipline, and capital strategy to match," Gitomer shared in a LinkedIn post. "I’m honored to take on this role ... I’m looking forward to partnering with the exceptional leadership team here at Axiom Space during a defining chapter for the company and commercial spaceflight broadly, as well as a crucial period for maintaining U.S. human presence in low-Earth orbit and leadership in space exploration."

Wegerer joins Axiom after most recently serving as CIO of Washington-based Insitu Inc., a subsidiary of Boeing that develops customized unmanned hardware for commercial, government and defense customers.

"My time at Insitu was defined by talented people, meaningful challenges, and work that mattered. I'm grateful for the teams, partners, and leaders who made progress there possible. Stepping into Axiom, I'm energized by the mission, the momentum, and the opportunity to help shape what's next," Wegerer shared.

Photo via LinkedIn

The duo was celebrated on the floor of the New York Stock Exchange last week.

“We are pleased to welcome these exceptional leaders to the Axiom Space team," Axiom CEO Jonathan Cirtain added in the announcement. “Their strong record of helping complex organizations advance their strategic priorities will strengthen our executive team to further advance our core business objectives."

It's been a busy summer for Axiom. The company tacked on an additional $175 million to a previously announced capital raise, bringing the oversubscribed round to a total of more than $525 million, in June.

It also announced plans to open a Japanese subsidiary July 1. It tapped veteran Japanese astronaut Koichi Wakata to lead Axiom Space Japan as chief technology officer in the Asia-Pacific region. It also shared plans to establish Axiom Space Switzerland, a wholly owned subsidiary based in Lucerne that is also expected to begin operations this summer.

Axiom also officially redomiciled its legal headquarters from Delaware to Texas last month. Read more here.

Houston hardtech accelerator names 8 founders to 2026 cohort

hardtech fellows

Hardtech-focused organization Activate has named 50 new members to its 2026 cohort of scientists, which includes eight startups joining Activate Houston.

Activate aims to support scientists at "the outset of their entrepreneurial journey." It partners with U.S.-based funders and research institutions to support its fellows in developing high-impact technology. Its fellows receive a living stipend, research and development funding, connections from Activate's robust network of mentors and access to a curriculum specific to the program for two years.

This year's fellows represent 41 companies from 22 U.S. cities and 11 states.

“This cohort clearly demonstrates that the next industry-defining companies won't choose between modern technology and deep science; they'll be built by combining both,” Cyrus Wadia, CEO of Activate, said in the announcement. “These are the scientists and engineers turning our most urgent global challenges into the companies that will deliver a more sustainable future.”

The Houston fellows are working across the energy, space, AI infrastructure and agriculture sectors. They include:

  • Sophie Clare Broun, founder of Anning Corporation, which is producing clean hydrogen by stimulating naturally occurring geologic deposits
  • Kathy Andersen, founder of Brint Tech, which builds optical sensing systems that quantify hydrogen for infrastructure operators
  • Dorsa Talebi, founder of Kinetiq Drive, which builds rare-earth-free, contact-free electric motors with wireless rotors for small appliances and heavy industry alike
  • Neethu Pottackal, founder of Nivera, which is developing natural, edible coatings made from agricultural byproducts to reduce food waste and extend the shelf life of fresh food
  • Jonathan Huffman, founder of Orbital Arc, which is shrinking spacecraft propulsion to a microchip powerful enough for deep space
  • Tim Lee, founder of Renesin, which develops advanced materials for faster, more efficient AI hardware
  • Joshua Livingston, founder of Selerra Separations, which is developing high-performance membranes that cut the cost and energy consumption of water treatment
  • Wenli Jiang, founder of SwieNitro Recovery, which is developing technology that converts nitrogen-rich waste streams into valuable fertilizer

"Home to the largest concentration of engineers in the United States and a dense ecosystem of Fortune 100 and Fortune 500 companies, Houston is uniquely positioned for scientists tackling large-scale industrial challenges. Activate Houston fellows are connected to the city's deep networks in energy, chemicals, and materials," Activate said in the announcement.

Activate named its inaugural Houston cohort in 2024. It has other hubs in Boston, New York, and Berkley, California—where Activate is headquartered. The organization also offers a virtual and remote cohort, known as Activate Anywhere. Nationally, it has supported 346 fellows and 276 companies since 2015.

Activate Houston is led by managing director Jeremy Pitts, who co-founded Greentown Labs in Boston. It is based out of the Ion. The latest cohort is Activate Houston's third. Read more about the last year's cohort here.

Rice, Houston Methodist award $90K for cancer research projects

seed grants

Rice University’s Synthesis X Center, in partnership with the Houston Methodist Neal Cancer Center, announced earlier this month the organizations would award $90,000 in seed grant funding to two projects that could help fight cancer. One would ease the pain of chemotherapy, while the other could change the way the progression of leukemia is tracked.

“We’re excited to be collaborating with the Neal Cancer Center to support collaborative, novel and interdisciplinary proposals to improve cancer care and outcomes,” Han Xiao, Rice professor of chemistry and the director of the SynthX Center, said in a news release. “Together, we can achieve translational excellence.”

The projects

Chemotherapy is one of the most effective cancer treatments, but it can be hard on the body. The human body doesn’t like being injected with radioactive material, especially the skin around the injection point, which can become extremely irritated. For patients in long-term treatment, the skin irritation can be more than just a bother; it can lead to infections that are dangerous to a compromised immune system.

Angel A Marti, a professor of chemistry at Rice University, and Biana Godin, an associate professor of nanoscience at Houston Methodist Research Institute, are experimenting with metal nanoclusters as a way to block radiation at the injection site. The nanocluster could be applied in a cream or a gel on the skin, serving as a type of shield against the harsh radioactive material.

Meanwhile, Yuan Ma, an assistant professor of chemistry at Rice, and Shu-Hsia Chen, a professor of immunology at Houston Methodist Research Institute, are working with m6A. Discovered in the 1970s, m6A is the most prevalent chemical modifier found in mRNA in mammals. It is prevalent in many cancers, including leukemia.

Ma and Chen are working on measuring the amount of m6A in leukemia to see if it can determine the most effective cancer treatments. The team is also experimenting with ways to shut off m6A to see if it makes current leukemia treatments more effective.

Progress from SynthX

SynthX was first launched in April 2024 to turn research from Rice and Houston Methodist into real-world cancer treatments. Within a year, the center had secured $1.5 million in grant money to work on crossing the blood-brain barrier in brain cancer treatments. These latest awards show that SynthX Center continues to bridge the worlds of research and clinical practice.

“This collaboration reflects a shared commitment to team science in cancer research,” Daniela Matei, the director of the Houston Methodist Neal Cancer Center, added in the release. “These are the types of translational and pioneering projects that lead to transformation in patient care.”'

The SynthX Center awarded $90,000 in seed grants to three teams in 2025 and $80,000 to three teams in 2024.