Here's a list of resources for Houston startups and small businesses during COVID-19 shutdown

here to help

Small businesses and startups are likely to hurt — and hurt bad — from COVID-19's affect on the economy. Here are some resources to get support. Photo by Hero Images

It's a trying time for the world, and Houston small businesses and startups have been put in a difficult spot. From having to work remotely or being forced to close or scale back operations due to mandates from the government, entrepreneurs are having to figure out their new normals.

However, organizations have leapt at the chance to help their fellow Houstonians, and a number of resources have appeared to provide aid to startups, from advice and resources to grants.

Editor's note: This article originally ran March 25, 2020, but has been updated and republished with more resources.

The Cannon's CERT Program

The Cannon released information about their Cannon Emergency Response Team Program, and Houston startups can apply online. The multi-week program is intended to provide aid and support for startups and small businesses experiencing a crisis caused by external forces — namely COVID-19 and its repercussions, but also natural disasters, market disruption, legislative actions, civil unrest, fraud, or theft.

Click here to apply and learn more.

The Ion's resource center

The Ion has also rounded up resources for its members and the greater Houston innovation ecosystem. It's available online, and has everything from links to national and local resources and financial assistance information to virtual events.

"While we all try and adjust to this new way of life, The Ion will continue to be a resource to our entrepreneurial community the best way we know how, by connecting our community and providing you with opportunities that you need to be resilient during these unstable times. ... We hope this page serves you well and we promise to keep you all up to date on everything innovation taking place in our community," writes Gaby Rowe, executive director of The Ion.

Rowe has also started a video series of interviews with Houston startups — the videos are also available on the webpage.

Click here to access the resource center.

Houston Exponential's virtual event calendar

Houston Exponential worked quickly to turn their online calendar featuring events across the innovation ecosystem in Houston to helpful virtual events. Anyone can submit an event for consideration.

Click here to find the calendar.

To find InnovationMap's curated list of events for April, click here.

The GHP's Greater Houston Business Recovery Center

The Greater Houston Partnership has released a one-stop shop for business help for companies large and small. The amalgamation combines several national and local options, including relevant information about the Coronavirus Aid, Relief, and Economic Security (CARES) Act.

"We know many Houston companies are hurting and do not have the resources to sustain themselves for weeks without help," said Bob Harvey, president and CEO of the Partnership. "The funds provided through the CARES Act are essential to ensure Houston businesses can meet payroll and cover other expenses during this difficult time. "

Click here to visit the Greater Houston Business Recovery Center page.

Fat Finger's procedure app

In an effort to help businesses organize their response, Houston-based tech company Fat Finger has released a procedure app that is available for free. It offers employee agreements, important protocol checklists, and more.

"Our intention is to help teams of all types operate as safe and effective as possible to overcome what we are all going through," writes James McDonough, founder and CEO of the company.

Click here to learn more about the app here.

Houston PR firm to offer free services

Houston-based Paige PR is offering up $5,000 worth of its services to help out a company affected by COVID-19., which includes media relations, influencer relations, media training, employee communication, content development, social media management, corporate event planning, campaign measurement, brand management, community engagement and crisis communication, according to a news release.

"Paige PR's mission is to empower and help businesses tell their unique stories and amplify their messages," says Paige Donnell, Paige PR's founder and CEO, in the release. "Our team wanted to give back and honor a company making a positive difference, despite these uncertain times. Now is not the time to halt your company's marketing and communication efforts. However, we understand that this may be the only option for some businesses. We're in this together, and all of us at Paige PR look forward to offering our services free of charge to one deserving company."

Click here to learn more and enter your company.

Gener8tor's free 1-week response program

Just like most accelerator programs, cohort schedules and plans have been affected by COVID-19, but one new-to-Houston program is making some lemonade out of the lemons they were served. Gener8tor, along with the Downtown Redevelopment Authority, announced a partnership for one week of virtual programming for small businesses affected by the COVID-19 outbreak. It's free and an extension of the gBETA program, which launched in Houston in January.

Interested entrepreneurs must apply to be enrolled by Friday, May 27. The week of virtual assistence begins March 30 and goes until April 3. Participants will have access to virtual office hours with experts.

"We have seen firsthand the impact that entrepreneurs have on a community and we hope to call on our network of mentors, investors, and partners to support these new Emergency Response Programs," says Joe Kirgues, Co-Founder of gener8tor, in a news release.

Click here to learn more and sign up.

Hello Alice's business center

Houston-based Hello Alice is a great digital resource for startups locally and beyond. The organization recently announced its grant program that will focus on funding minority-founded startups and quickly snapped into action to create a COVID-19 Business Center free for entrepreneurs to use.

Alice is offering emergency grants to businesses affected by COVID-19 and has also gathered other resources like mental health information, tips for running a remote workforce, and more.

Click here to access the business center.

The Small Business Administration's webinars and disaster loans

Startups, nonprofits, and small businesses can apply for an Economic Injury Disaster Loans for up to $2 million. For small businesses, the interest rate is 3.75 percent, and for nonprofits, the interest rate is 2.75 percent. The SBA's Houston chapter is available for help as well.

Click here to learn more about the EIDLs.

Impact Hub Houston's comprehensive list

If this list here isn't exhaustive enough, Impact Hub Houston has gone the extra mile on their blog, creating a comprehensive and updated list of resources for small businesses and startups, as well as for people in general. There is everything from information on small business financial help and online education to tips for parents and health-related resources.

Click here to access the guide.

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Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

Elon Musk's SpaceX site officially becomes the city of Starbase, Texas

Starbase, Texas

The South Texas home of Elon Musk’s SpaceX rocket company is now an official city with a galactic name: Starbase.

A vote Saturday, May 3, to formally organize Starbase as a city was approved by a lopsided margin among the small group of voters who live there and are mostly Musk’s employees at SpaceX. With all the votes in, the tally was 212 in favor to 6 against, according to results published online by the Cameron County Elections Department.

Musk celebrated in a post on his social platform, X, saying it is “now a real city!”

Starbase is the facility and launch site for the SpaceX rocket program that is under contract with the Department of Defense and NASA that hopes to send astronauts back to the moon and someday to Mars.

Musk first floated the idea of Starbase in 2021 and approval of the new city was all but certain. Of the 283 eligible voters in the area, most are believed to be Starbase workers.

The election victory was personal for Musk. The billionaire’s popularity has diminished since he became the chain-saw-wielding public face of President Donald Trump’s federal job and spending cuts, and profits at his Tesla car company have plummeted.

SpaceX has generally drawn widespread support from local officials for its jobs and investment in the area.

But the creation of an official company town has also drawn critics who worry it will expand Musk’s personal control over the area, with potential authority to close a popular beach and state park for launches.

Companion efforts to the city vote include bills in the state Legislature to shift that authority from the county to the new town’s mayor and city council.

All these measures come as SpaceX is asking federal authorities for permission to increase the number of South Texas launches from five to 25 a year.

The city at the southern tip of Texas near the Mexico border is only about 1.5 square miles (3.9 square kilometers), crisscrossed by a few roads and dappled with airstream trailers and modest midcentury homes.

SpaceX officials have said little about exactly why they want a company town and did not respond to emailed requests for comment.

“We need the ability to grow Starbase as a community,” Starbase General Manager Kathryn Lueders wrote to local officials in 2024 with the request to get the city issue on the ballot.

The letter said the company already manages roads and utilities, as well as “the provisions of schooling and medical care” for those living on the property.

SpaceX officials have told lawmakers that granting the city authority to close the beach would streamline launch operations. SpaceX rocket launches and engine tests, and even just moving certain equipment around the launch base, requires the closure of a local highway and access to Boca Chica State Park and Boca Chica Beach.

Critics say beach closure authority should stay with the county government, which represents a broader population that uses the beach and park. Cameron County Judge Eddie Trevino, Jr. has said the county has worked well with SpaceX and there is no need for change.

Another proposed bill would make it a Class B misdemeanor with up to 180 days in jail if someone doesn’t comply with an order to evacuate the beach.

The South Texas Environmental Justice Network, which has organized protests against the city vote and the beach access issue, held another demonstration Saturday that attracted dozens of people.

Josette Hinojosa, whose young daughter was building a sandcastle nearby, said she was taking part to try to ensure continued access to a beach her family has enjoyed for generations.

With SpaceX, Hinojosa said, “Some days it’s closed, and some days you get turned away."

Organizer Christopher Basaldú, a member of the Carrizo/Comecrudo Nation of Texas tribe, said his ancestors have long been in the area, where the Rio Grande meets the Gulf.

“It’s not just important,” he said, “it’s sacred.”

Texas-based 'DoorDash for laundry' startup tumbles into Houston market

No Scrubs

Laundry may seem like an endless task that piles up, but a new service offers a solution to overwhelmed Houston families.

NoScrubs, an Austin-based home laundry pickup service has just expanded to Houston. Described by the company as "DoorDash — but for laundry," they wash customer's clothes at local laundromats and return them the same day, folded and ready to be put away.

The service took off like gangbusters in Austin, making an expansion to the state's largest city an obvious choice. It's not universal coverage just yet.

For now, only the following ZIP codes have NoScrubs service available: 77002, 77004, 77005, 77006, 77007, 77008, 77009, 77010, 77018, 77019, 77024, 77025, 77027, 77046, 77056, 77057, 77081, 77098, 77401, 77030, 77003.

A single pickup starts at $40 for 20 pounds of laundry, while the basic monthly subscription is $60 for two pickups. All services use hypoallergenic detergents.

The average American family spends about 240 hours a year on laundry, making it a very time-consuming chore. For people with disabilities, difficult work schedules, and other circumstances, it can be a real help, says co-founder Matt O'Connor.

"Some of our favorite customer stories simply revolve around saving people time when they have something challenging going on," he writes in an email. "For example, one customer reviewed NoScrubs saying 'So happy I could cry! (Partially because I'm pregnant and my emotions are heightened!)...1000% recommend if you have time restrictions or physical restrictions! ' So, whether it’s saving time, the affordability, or the pleasantly surprising turnaround time, NoScrubs has a variety of benefits for any customer."

NoScrubs is also a new opportunity for Houston's gig workers. Because there are no passengers, it can be a safer alternative to driving ride share for women and other people apprehensive about having strangers in their cars. As NoScrubs partners with local laundromats, drivers are also going to centralized locations rather than all over the map, leading to less wear and tear on their cars. The laundromats benefit as well, since NoScrubs loads are ones that would otherwise be done at home.

"Our model makes driving a tiny fraction of the time, so folks who don’t want to wear down their vehicles and spend a ton on gas love working at NoScrubs," added O'Connor.

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