Elizabeth Holmes, pictured on November 18, is now incarcerated. Photo by Justin Sullivan/Getty Images

A longtime Houstonian is coming home — by way of prison.

Elizabeth Holmes, the disgraced founder of blood-testing startup Theranos, reported to F.P.C. Bryan, on Tuesday, May 30, per multiple news outlets. She is set to serve 11 years and three months in the women's minimum-security prison located some 90 minutes from Houston hometown.

According to the the New York Times, the onetime Tanglewood resident arrived at the prison in a Ford Expedition that appeared to be driven by her mother, Noel Holmes. Her father, Christian Holmes, appeared to be inside.

The Times adds that after some shuffling around, out of the view of the cameras gathered nearby, Holmes entered the facility wearing jeans, glasses and a sweater, and carrying some papers.

Prior to her arrival in Bryan, Holmes, 39, spent Memorial Day weekend with her family on the beach near her oceanfront San Diego home with her partner Billy Evans and their two children, according to the Daily Mail.

As CultureMap previously reported, Holmes was sentenced to more than 11 years in prison on November 18, 2002 in San Jose, California following her conviction in January that year for defrauding Theranos investors.

Actress Amanda Seyfried, who played Holmes in the Hulu series The Dropout, shared her thoughts on the woman she portrayed to great acclaim. “Life’s not fair,” Seyfried noted on Good Morning America on Tuesday, “but in a lot of ways, it’s fair. For her, in particular.”

Thrust into the spotlight as the new face of white-collar, Silicon Valley fraud, Holmes now serves as a warning to those who might consider a similar path, her sentencing judge made clear.

“I suppose we step back and ask what is the pathology of fraud? Is it the refusal to accept responsibility or express contrition in any way?" Judge Edward Davila said during the ruling, according to Yahoo! Finance. "Perhaps that is the cautionary tale that will go forward from this case."

Davila ordered Holmes to turn herself into custody on April 27, 2023.

Specifically, Holmes' sentence is 11 years and three months in prison, with another three years of supervision after release. Additionally, Holmes and her ex-boyfriend and former Theranos COO Ramesh “Sunny” Balwani have been ordered to pay $452 million to their fraud victims.

Once compared to disruptors and innovators Steve Jobs and Bill Gates, Holmes rose to fame by enticing investors with the promise that her Theranos could run hundreds of blood tests via a simple pin prick. Buzz for Theranos grew to the point that Theranos was valued at $9 billion, which made Holmes the world’s first self-made female billionaire.

Yet, after securing more than $900 million in funding, Theranos was proven to be essentially bogus by the Wall Street Journal in 2015.

Facing up to 20 years in prison, a tearful Holmes, who is pregnant, addressed the court. "I stand before you taking responsibility for Theranos," she said, per Yahoo. "I loved Theranos. It was my life’s work. My team meant the world to me. They wanted to make a difference in the world. I am devastated by my failings," she said. "Every day for the past years, I have felt deep pain for the people…those people who believe in us and those patients. I worked so hard to serve. I gave everything I had to try to to build...Theranos. Looking back, there are so many things I would do differently. I tried to realize my dream too quickly."

Holmes is the subject of the aforementioned series, The Dropout, which centers on her early life in Houston, where she grew up in Tanglewood and attended St. John's School. Her father's layoff from Enron is presented as clearly an inciting incident in her life. As The Dropout depicts, Holmes would meet boyfriend/partner Ramesh "Sunny" Balwani, drop out of Stanford, and launch Theranos.

One of the most memorable lines in the miniseries comes when a young Holmes plainly states her goals at a family gathering. "I wanna be a billionaire," she said plainly — a memorable and clearly prophetic statement.

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This article originally ran on CultureMap.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.