3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Dr. Evan Collins of Houston Methodist, Margarita Kelrikh of Pillsbury, and Howard Berman of Coya Therapeutics. Photos courtesy

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes a new innovator in residency, a Houston startup lawyer, and a neurodegenerative therapeutics CEO.

Evan Collins, innovator in residency at Houston Methodist

Dr. Evan Collins, an orthopedic surgeon and chief of the Houston Methodist Hand & Upper Extremity Center, was named the hospital's first innovator in residency. Photo via drevancollins.com

Dr. Evan Collins, an orthopedic surgeon and chief of the Houston Methodist Hand & Upper Extremity Center, is the inaugural innovator in residency at Houston Methodist Center for Innovation.

What does an innovator-in-residency do? Collins sat down with InnovationMap to explain. His role, he explains, is to encourage other clinicians to get involved in the innovation process, particularly using digital health care programs.

“When you look at all the technology, especially the digital technology that's being applied [in medicine], and the future of digital technology, whether you define it as AI or other variations, having a clinical perspective to vet a lot of these possible solutions, as opposed to just keeping it on the administrative side of things, has greater value,” he says. Read more.

Margarita Kelrikh, counsel at Pillsbury

Margarita Kelrikh joins the Houston Innovators Podcast to discuss her career, legal tips for startups, and why she's dedicated to the Houston startup community. Photo courtesy

After working at WeWork and its upstart competitor for several years, Margarita Kelrikh realized it was time to move back into a law firm where she could help more early stage Houston startup clients. She recently joined Pillsbury's Houston office as counsel.

"I realized I wanted to work with the people who I worked with in the past, and the only way I could do that is if I went back to a law firm," she says, explaining that working in house means you can only have one client: your employer. "It's about having that variety and being able to work with a wide array of people."

Kelrikh shares some of her go-to startup legal advice on this week's episode of the Houston Innovators Podcast, and she emphasizes how ready and willing she is to serve the Houston startup community. Read more.

Howard Berman, CEO and co-founder of Coya Therapeutics

Coya Therapeutics is looking into how a trendy weight loss drug could complement its Alzheimer’s disease treatment. Photo via LinkedIn

Glucagon-like peptide 1, or GLP-1, agonists are all the rage right now thanks to drugs like Ozempic and Wegovy. Though they’re currently being prescribed for diabetes and weight loss, a Houston company reports that it may have found another use for GLP-1s.

Coya Therapeutics, a publicly traded clinical-stage biotechnology company, has filed intellectual property protection for a combination of its proprietary COYA 301 and GLP-1. Coya’s team believes that combining COYA 301, a low-dose interleukin-2 (IL-2) intended to enhance the anti-inflammatory function of regulatory T cells (Tregs), with GLP-1 could be a game-changer in the fight against Alzheimer’s disease.

According to Coya’s CEO, Howard Berman, “We believe that combination immunotherapy approaches will evolve to play a meaningful role in treating complex immune-based diseases that are driven by a host of pathophysiologic mechanisms.” Read more.

Dr. Evan Collins, an orthopedic surgeon and chief of the Houston Methodist Hand & Upper Extremity Center, was named the hospital's first innovator in residency. Photo via drevancollins.com

Houston Methodist names orthopedic surgeon as inaugural innovator in residency

leading medicine

Houston Methodist Center for Innovation has named its first innovator in residency.

Roberta Schwartz, executive vice president and chief innovation officer at Methodist, chose Dr. Evan Collins, an orthopedic surgeon and chief of the Houston Methodist Hand & Upper Extremity Center, for the role.

“Dr. Collins has been a physician champion for innovation projects over the past few years and will be an exceptional asset for our team to help involve physicians more actively in innovation throughout our hospital system,” Schwartz wrote on LinkedIn.

So what does an innovator-in-residency do? Collins sat down with InnovationMap to explain.

His role, he explains, is to encourage other clinicians to get involved in the innovation process, particularly using digital health care programs. “Innovating is great, but the information that's coming has to be actionable in a way that fits a business model and answers significant questions in health care,” says the New York native.

He uses the metaphor of an Apple Watch’s sleep tracker to illustrate what is perhaps less than actionable. After all, you wake up knowing if you slept well without a device telling you about the quality of your night’s rest. His job, then, is vetting opportunities and technologies with the goal of deciding what may make a good return on its investment.

“‘Does it increase my capacity to see patients? Does it improve things in a meaningful way?’,” he asks. “It's looking at the opportunities within health care, but applying some rigor to it from a clinical perspective to vet, ‘Is this really going to give us actionable information where we can create value when this thing is produced?’”

Collins jokes that he was chosen for the role because he “got the short straw.” But his background speaks for itself. He’s been at Methodist for 27 years and received his MBA from Rice University’s Jesse H. Jones Graduate School of Business in 2013. He’s used his expertise to improve efficiency in the operating room, allowing him to help more patients than ever before.

“Maybe they saw this as another opportunity to give input that could be helpful and contribute to the organization and I'm grateful for that opportunity,” says Collins. The “they” he’s referring to is Schwartz, but also Marc L. Boom, Methodist’s forward-thinking president and CEO. “They recognize the importance of what we're trying to do here for the future of health care. So I think I'm grateful for that opportunity, but they are the ones that create that opportunity for me to contribute.”

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U.S. News names 5 Houston suburbs as the best places to retire in 2026

Retirement Report

Houston-area suburbs should be on the lookout for an influx of retirees in 2026. A new study by U.S. News and World Report has declared The Woodlands and Spring as the fourth and fifth best cities to retire in America, with three other local cities making the top 25.

The annual report, called "250 Best Places to Retire in the U.S. in 2026" initially compared 850 U.S. cities, and narrowed the list down to a final 250 cities (up from 150 previously). Each locale was analyzed across six indexes: quality of life for individuals reaching retirement age, value (housing affordability and cost of living), health care quality, tax-friendliness for retirees, senior population and migration rates, and the strength of each city's job market.

Midland, Michigan was crowned the No. 1 best place to retire in 2026. The remaining cities that round out the top five are Weirton, West Virginia (No. 2) and Homosassa Springs, Florida (No. 3).

According to U.S. News, about 15 percent of The Woodlands' population is over the age of 65. The median household income in this suburb is $139,696, far above the national average median household income of $79,466.

Though The Woodlands has a higher cost of living than many other places in the country, the report maintains that the city "offers a higher value of living compared to similarly sized cities."

"If you want to buy a house in The Woodlands, the median home value is $474,279," the city's profile on U.S. News says. "And if you're a renter, you can expect the median rent here to be $1,449." For comparison, the report says the national average home value is $370,489.

Spring ranked as the fifth best place to retire in 2026, boasting a population of more than 68,000 residents, 11 percent of whom are seniors. This suburb is located less than 10 miles south of The Woodlands, while still being far enough away from Houston (about 25 miles) for seniors to escape big city life for the comfort of a smaller community.

"Retirees are prioritizing quality of life over affordability for the first time since the beginning of the COVID-19 pandemic," said U.S. News contributing editor Tim Smart in a press release.

The median home value in Spring is lower than the national average, at $251,247, making it one of the more affordable places to buy a home in the Houston area. Renters can expect to pay a median $1,326 in monthly rent, the report added.

Elsewhere in Houston, Pearland ranked as the 17th best place to retire for 2026, followed by Conroe (No. 20) and League City (No. 25).

Other Texas cities that ranked among the top 50 best places to retire nationwide include Victoria (No. 12), San Angelo (No. 28), and Flower Mound (No. 37).

The top 10 best U.S. cities to retire in 2026 are:

No. 1 – Midland, Michigan
No. 2 – Weirton, West Virginia
No. 3 – Homosassa Springs, Florida
No. 4 – The Woodlands, Texas
No. 5 – Spring, Texas
No. 6 – Rancho Rio, New Mexico
No. 7 – Spring Hill, Florida
No. 8 – Altoona, Pennsylvania
No. 9 – Palm Coast, Florida
No. 10 – Lynchburg, Virginia

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This article originally appeared on CultureMap.com.

Micro-nuclear reactor to launch at Texas A&M innovation campus in 2026

nuclear pilot

The Texas A&M University System and Last Energy plan to launch a micro-nuclear reactor pilot project next summer at the Texas A&M-RELLIS technology and innovation campus in Bryan.

Washington, D.C.-based Last Energy will build a 5-megawatt reactor that’s a scaled-down version of its 20-megawatt reactor. The micro-reactor initially will aim to demonstrate safety and stability, and test the ability to generate electricity for the grid.

The U.S. Department of Energy (DOE) fast-tracked the project under its New Reactor Pilot Program. The project will mark Last Energy’s first installation of a nuclear reactor in the U.S.

Private funds are paying for the project, which Robert Albritton, chairman of the Texas A&M system’s board of regents, said is “an example of what’s possible when we try to meet the needs of the state and tap into the latest technologies.”

Glenn Hegar, chancellor of the Texas A&M system, said the 5-megawatt reactor is the kind of project the system had in mind when it built the 2,400-acre Texas A&M-RELLIS campus.

The project is “bold, it’s forward-looking, and it brings together private innovation and public research to solve today’s energy challenges,” Hegar said.

As it gears up to build the reactor, Last Energy has secured a land lease at Texas A&M-RELLIS, obtained uranium fuel, and signed an agreement with DOE. Founder and CEO Bret Kugelmass said the project will usher in “the next atomic era.”

In February, John Sharp, chancellor of Texas A&M’s flagship campus, said the university had offered land at Texas A&M-RELLIS to four companies to build small modular nuclear reactors. Power generated by reactors at Texas A&M-RELLIS may someday be supplied to the Electric Reliability Council of Texas (ERCOT) grid.

Also in February, Last Energy announced plans to develop 30 micro-nuclear reactors at a 200-acre site about halfway between Lubbock and Fort Worth.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston falls from top 50 in global ranking of 'World's Best Cities'

Rankings & Reports

Houston is no longer one of the top 50 best cities in the world, according to a prestigious annual report by Canada-based real estate and tourism marketing firm Resonance Consultancy.

The newest "World's Best Cities" list dropped Houston from No. 40 last year to No. 58 for 2026.

The experts at Resonance Consultancy annually compare the world's top 100 cities with metropolitan populations of at least 1 million residents or more based on the relative qualities of livability, "lovability," and prosperity. The firm additionally collaborated with AI software company AlphaGeo to determine each city's "exposure to risk, adaptation capacity," and resilience to change.

The No. 1 best city in the world is London, with New York (No. 2), Paris (No. 3), Tokyo (No. 4), and Madrid (No. 5) rounding out the top five in 2026.

Houston at least didn't rank as poorly as it did in 2023, when the city surprisingly plummeted as the 66th best city in the world. In 2022, Houston ranked 42nd on the list.

Despite dropping 18 places, Resonance Consultancy maintains that Houston "keeps defying gravity" and is a "coveted hometown for the best and brightest on earth."

The report cited the Houston metro's ever-growing population, its relatively low median home values ($265,000 in 2024), and its expanding job market as top reasons for why the city shouldn't be overlooked.

"Chevron’s shift of its headquarters from California to Houston, backed by $100 million in renovations, crowns relocations drawn by record 2024 Port Houston throughput of more than four million containers and a projected 71,000 new jobs in 2025," the report said.

The report also draws attention to the city's diversity, spanning from the upcoming grand opening of the long-awaited Ismaili Center, to the transformation of several industrial buildings near Memorial City Mall into a mixed-use development called Greenside.

"West Houston’s Greenside will convert 35,000 square feet of warehouses into a retail, restaurant and community hub around a one-acre park by 2026, while America’s inaugural Ismaili Center remains on schedule for later this year," the report said. "The gathering place for the community and home for programs promoting understanding of Islam and the Ismaili community is another cultural jewel for the country’s most proudly diverse major city."

In Resonance Consultancy's separate list ranking "America's Best Cities," Houston fell out of the top 10 and currently ranks as the 13th best U.S. city.

Elsewhere in Texas, Austin and Dallas also saw major declines in their standings for 2026. Austin plummeted from No. 53 last year to No. 87 for 2026, and Dallas fell from No. 53 to No. 78.

"In this decade of rapid transformation, the world’s cities are confronting challenges head‑on, from climate resilience and aging infrastructure to equitable growth," the report said. "The pandemic, long forgotten but still a sage oracle, exposed foundational weaknesses – from health‑care capacity to housing affordability. Yet, true to their dynamic nature, the leading cities are not merely recovering, but setting the pace, defining new paradigms of innovation, sustainability and everyday livability."

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