Rice University spinout lands $500K NSF grant to boost chip sustainability

cooler computing

HEXAspec, founded by Tianshu Zhai and Chen-Yang Lin, has been awarded an NSF Partnership for Innovation grant. Photo courtesy of Rice

HEXAspec, a spinout from Rice University's Liu Idea Lab for Innovation and Entrepreneurship, was recently awarded a $500,000 National Science Foundation Partnership for Innovation grant.

The team says it will use the funding to continue enhancing semiconductor chips’ thermal conductivity to boost computing power. According to a release from Rice, HEXAspec has developed breakthrough inorganic fillers that allow graphic processing units (GPUs) to use less water and electricity and generate less heat.

The technology has major implications for the future of computing with AI sustainably.

“With the huge scale of investment in new computing infrastructure, the problem of managing the heat produced by these GPUs and semiconductors has grown exponentially. We’re excited to use this award to further our material to meet the needs of existing and emerging industry partners and unlock a new era of computing,” HEXAspec co-founder Tianshu Zhai said in the release.

HEXAspec was founded by Zhai and Chen-Yang Lin, who both participated in the Rice Innovation Fellows program. A third co-founder, Jing Zhang, also worked as a postdoctoral researcher and a research scientist at Rice, according to HEXAspec's website.

The HEXASpec team won the Liu Idea Lab for Innovation and Entrepreneurship's H. Albert Napier Rice Launch Challenge in 2024. More recently, it also won this year's Energy Venture Day and Pitch Competition during CERAWeek in the TEX-E student track, taking home $25,000.

"The grant from the NSF is a game-changer, accelerating the path to market for this transformative technology," Kyle Judah, executive director of Lilie, added in the release.

From Your Site Articles
Here's what student-founded startups are leaving CERAWeek with fresh funding. Photo courtesy of HETI

Houston clean tech startup pitch competition names winners at annual CERAWeek event

pitch perfect

For the third year, the Greater Houston Partnership's Houston Energy Transition Institute hosted its startup pitch competition at CERAWeek by S&P Global. A dozen startups walked away with recognition — and three some with cash prizes.

HETI joined partners Rice Alliance for Technology and Entrepreneurship and TEX-E for the 2024 Energy Venture Day and Pitch Competition at CERAWeek on Wednesday, March 20. Forty-two companies, which have collectively raised over $265 million in investment funding already, pitched to judges. Nine startups won awards across three tracks.

TEX-E, a Texas nonprofit that supports student-founded upstarts, had five of its companies pitch and three winners walked away with monetary prizes. Teams that competed in the TEX-E Prize track, many of which come from Houston universities, include:

  • AirMax, University of Texas at Austin
  • BeadBlocker, University of Houston
  • Carvis Energy Solutions, Texas A&M University
  • Coflux Purification, Rice University
  • Solidec, Rice University

Solidec, which is working on a platform to produce chemicals from captured carbon, won first place and $25,000. The company also recently scored a $100,000 grant from Rice's One Small Step Grant program, as well as a voucher from the DOE. Coflux Purification, which has a technology that destroys PFAS in filtration, won second place and$15,000. The company also secured a One Small Step Grant to the tune of $80,000. AirMax, which focuses on optimizing sustainability for air conditioning equipment, won third place and $10,000.

Last year, Houston-based Helix Earth Technologies took home the top TEX-E price and $25,000 cash awards. The venture, founded by Rawand Rasheed and Brad Husick from Rice University, developed high-speed, high-efficiency filter systems derived from technology originating at NASA.

The rest of the companies that pitched competed for non-monetary awards. Here's what companies won:

  • Group A (CCUS, oilfield solutions, analytics and minerals):
    • First place: Ardent
    • Second place: Vaulted Deep
    • Third place: Mitico
  • Group B (batteries, renewables, water, and grid technology):
    • First place: SungreenH2
    • Second place: FeX Energy
    • Third place: Mercurius Biorefining
  • Group C (Mobility, Materials, and hydrogen solutions)
    • First place: Thiozen
    • Second place: Power2Hydrogen
    • Third place: Arolytics
HETI, Rice Alliance, and TEX-E celebrated the winners at a private reception on Wednesday evening.
The Rice Alliance for Technology and Entrepreneurship identified eight startups that are best suited for disrupting energy tech and innovation. Photo courtesy of Rice Alliance

Rice Alliance pitch event identifies 8 most-promising energy tech startups

ones to watch

In honor of CERAWeek, the Rice Alliance for Technology and Entrepreneurship hosted its annual Energy Venture Day.

After over 50 startup pitches and more than 300 meetings, venture investors identified eight startups that are the most-promising companies on a path to innovate and disrupt the energy ecosystem.

The 2023 Energy Venture Day's Most-Promising Startup winners were:

AeroShield Materials

Graphic via aeroshield.tech

Hyde Park, Massachusetts-based AeroShield Materials is creating thermally insulating transparent inserts. The inserts are only four millimeters of AeroShield's material and, when placed inside a double-pane window, provides 65 percent more energy efficiency.

Columbia Power Technologies (C-Power)

Image via cpower.co

C-Power, based in Charlottesville, Virgina, has a technology that harnesses the power of the ocean.

"C-Power delivers this renewable energy resource to the world, both through low-power solutions that bring energy and the cloud to the sea and large-scale solutions that help decarbonize terrestrial grids," the company's website reads.

EarthEn

Graphic via earthen.energy

Chandler, Arizona-based EarthEn is focused on long duration energy storage solutions that use CO2 in a closed loop to store 4 to 100 hours of energy at a low cost. The SaaS tools — with artificial intelligence and machine learning — optimize peak demand pricing and use predictive analysis to enable grid resiliency.

Group1

Photo via Twitter

Group 1, based in Austin, is focused on the commercialization of potassium-ion batteries. The core technology originates from the labs of University of Texas at Austin professor JB Goodenough, co-inventor of the lithium-ion battery.

Ionada Carbon Solutions

Photo via ionada.com

Houston-based Ionada, a member of Halliburton Labs, has created a technology that can remove up to 99 percent of the carbon dioxide emissions for the energy, marine, and e-fuels, according to the company.

"Our engineers have more than a century of combined expertise in reducing emissions for the power generation, chemical, road, rail, air and marine industries. We are here to help you find the best sustainable solution to reduce your emissions," reads the website.

H Quest Vanguard

Photo courtesy of Halliburton

Another Halliburton Labs member H Quest Vanguard, headquartered in Pittsburgh, has developed an electrically powered chemical conversion platform that leverages Microwave Plasma Pyrolysis to liberate zero-CO2 hydrogen from natural gas using only a quarter of energy required by electrolysis, while coproducing a high-value carbon or petrochemical coproduct.

Pressure Corp

Photo by Anton Petrus/Getty

Houston-based Pressure Corp is developing waste pressure power systems to help midstream gas companies solve how they reduce emissions by providing the technology, capital and expertise required to achieve their environmental, social and governance goals.

STARS Technology

Photo via starsh2.com

Based in Richland, Washington, STARS Technology Corp. is commercializing advanced micro-channel chemical process technology that originally was designed for NASA and the Department of Energy. The company's reactors and heat exchangers are compact, energy-efficient, and more.

Here's what interactive, virtual events to log on to this month. Getty Images

10+ can't-miss virtual business and innovation events in Houston for May

Where to be online

While some things in Houston are starting to open back up, society hasn't yet established a timeline for when groups of more than 10 people will be allowed to safely gather. But, the programming must go on.

With that in mind, here are over 10 Houston innovation events you can attend virtually via online meetings. Be sure to register in advance, as most will send an access link ahead of the events.

May 4: Post-COVID Fund: Venture Investing in the Post-COVID World

Join Alumni Ventures Group for a webinar that explores how changes resulting from the COVID-19 pandemic will create profound change—as well as unique opportunities for new ventures that tackle these challenges.

Details: The event is at 3 p.m. on Monday, May 4. Learn more.

May 5 — Sell Your Science: Developing a Non-Confidential Pitch for in Person and Virtual Presentations

Learn tricks in preparing a non-confidential pitch deck along with tips that are aimed to help you sell your science at in person meetings or virtually.

Details: The event is at 11 a.m. on Tuesday, May 5. Learn more.

May 6 — Impacting Public Health: How Can My Idea Be A Part of the Solution?


When a pandemic hits, as a start-up company you may find that your technology can be aligned to help. However, now your timeline is expedited with a global health emergency and you need to get your technology into the market. How do you start to connect with the right players to get your technology into the U.S. market to make an impact on public health safety and security?

Details: The event is at 1 p.m. on Wednesday, May 6. Learn more.

May 6 — Virtual Event with Cindy Eckert - Expert Entrepreneur with Over $1B Exits

Cindy Eckert is an expert entrepreneur with over $1B in Exits, CEO of Sprout Pharmaceutical, and Founder of The Pink Ceiling. Attend the virtual fireside chat between Cindy Eckert and Femtech Focus founder Dr. Brittany Barreto.

Details: The event is at 2 p.m. on Wednesday, May 6. Learn more.

May 6 — Curious About Starting a Career in Tech?

One thing we know is that web developers come from different backgrounds. From teaching to consulting, design to accounting, and they're here to tell you about making that transition. Hear from professional developers in the field about how their careers lead them what they're working on now, how they got there, and how their past experiences apply to the work they do currently. Join General Assembly if you are curious about starting a career in tech, but not sure exactly where to begin.

Details: The event is at 6 p.m. on Wednesday, May 6. Learn more.

May 7 — Rice Alliance Energy Tech Venture Day

Originally scheduled to be hosted at OTC, Rice Alliance Energy Venture Day will now be a virtual event to allow startups to connect with investors and energy companies. The event will showcase about 40 promising energy technology companies. These companies have initial funding and are seeking their A, B, C, or later rounds with technology validation, field trial experience, and/or initial company revenue. The event offers a great opportunity for viewers to learn more about innovative technologies and provides companies with access to potential partners and investment opportunities.

Details: The event is at 9 a.m. on Thursday, May 7. Learn more.

May 8 — Lunch & Learn: Startup Funding Rounds

Seemingly every company wants to raise venture capital, but few founders are equipped to navigate the tangled mess of rounds, investment types, and investor expectations. At the end of this presentation, you will have a better handle on whether venture capital is right for your business and what it'll take to navigate from angels to exit.

Details: The event is at 11:30 a.m. on Friday, May 8. Learn more.

May 12 — Lunch and Learn with Asian Pacific American Entrepreneurs

According to New American Economy, Asian Pacific American entrepreneurs account for nearly a million of our nation's businesses. Whether it's apps, restaurants, social services, or consumer products, it's obvious that the entrepreneurial spirit is high in our nation. Let's hear it from our AAPI small business owners who will walk us through the triumphs and challenges they've faced while running their business and how they're making it work during a shaky period.

Details: The event is at noon on Tuesday, May 12. Learn more.

May 13-14 — 2020 Texas A&M New Ventures Competition

TNVC 2020 will be entirely virtual this year. This event is the culmination of a yearlong effort to identify and provide support to Texas-best technology ventures. There will be several private semi-finals judging rounds on May 13, with an Entrepreneurial Perspectives panel and Q&A with past winners and successful entrepreneurs. The finals will be on the 14th, followed by elevator pitches and an awards ceremony, all of which are open to the entire audience.

Details: The event is on Wednesday, May 14, and Thursday, May15. Learn more.

May 15 — How to Land a Job at a Tech Startup

Join General Assembly for this online event where a panel of tech startup talent acquisition professionals will take you through what types of opportunities exist in today's talent market, how the experience at a startup will make you more marketable in the long run, what talent acquisition professionals are actually thinking while reading resumes, advice for remote interviewing, and more.

Details: The event is at noon on Friday, May 15. Learn more.

May 29 — Mothers in Tech Breakfast

In celebration of Mother's Day, join General Assembly for a virtual breakfast featuring hard-working mothers that are also succeeding in their respective industries. A few incredible mothers will share their insights on how they reached their level of success, advice on navigating the workplace as a working mom, and how we can help the next generation of mothers in tech. Get ready for an honest, vulnerable, and insightful conversation.

    Details: The event is at 10 a.m. on Friday, May 29. Learn more.​

    Ad Placement 300x100
    Ad Placement 300x600

    CultureMap Emails are Awesome

    Property Showcase

    Rice Alliance and the Ion leader Brad Burke to retire this summer

    lasting legacy

    Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

    Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

    “Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

    During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

    “Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

    One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

    Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

    Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

    In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

    “Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

    Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

    “The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

    Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

    Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

    cancer research

    With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

    Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

    Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

    “Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

    In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

    With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

    Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

    Houston booms as No. 2 U.S. metro for new home construction

    Construction Boom

    Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

    Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

    Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

    Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

    A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

    Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

    Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

    Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

    While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

    “Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

    View All Listings