HEXAspec, founded by Tianshu Zhai and Chen-Yang Lin, has been awarded an NSF Partnership for Innovation grant. Photo courtesy of Rice

HEXAspec, a spinout from Rice University's Liu Idea Lab for Innovation and Entrepreneurship, was recently awarded a $500,000 National Science Foundation Partnership for Innovation grant.

The team says it will use the funding to continue enhancing semiconductor chips’ thermal conductivity to boost computing power. According to a release from Rice, HEXAspec has developed breakthrough inorganic fillers that allow graphic processing units (GPUs) to use less water and electricity and generate less heat.

The technology has major implications for the future of computing with AI sustainably.

“With the huge scale of investment in new computing infrastructure, the problem of managing the heat produced by these GPUs and semiconductors has grown exponentially. We’re excited to use this award to further our material to meet the needs of existing and emerging industry partners and unlock a new era of computing,” HEXAspec co-founder Tianshu Zhai said in the release.

HEXAspec was founded by Zhai and Chen-Yang Lin, who both participated in the Rice Innovation Fellows program. A third co-founder, Jing Zhang, also worked as a postdoctoral researcher and a research scientist at Rice, according to HEXAspec's website.

The HEXASpec team won the Liu Idea Lab for Innovation and Entrepreneurship's H. Albert Napier Rice Launch Challenge in 2024. More recently, it also won this year's Energy Venture Day and Pitch Competition during CERAWeek in the TEX-E student track, taking home $25,000.

"The grant from the NSF is a game-changer, accelerating the path to market for this transformative technology," Kyle Judah, executive director of Lilie, added in the release.

Here's what student-founded startups are leaving CERAWeek with fresh funding. Photo courtesy of HETI

Houston clean tech startup pitch competition names winners at annual CERAWeek event

pitch perfect

For the third year, the Greater Houston Partnership's Houston Energy Transition Institute hosted its startup pitch competition at CERAWeek by S&P Global. A dozen startups walked away with recognition — and three some with cash prizes.

HETI joined partners Rice Alliance for Technology and Entrepreneurship and TEX-E for the 2024 Energy Venture Day and Pitch Competition at CERAWeek on Wednesday, March 20. Forty-two companies, which have collectively raised over $265 million in investment funding already, pitched to judges. Nine startups won awards across three tracks.

TEX-E, a Texas nonprofit that supports student-founded upstarts, had five of its companies pitch and three winners walked away with monetary prizes. Teams that competed in the TEX-E Prize track, many of which come from Houston universities, include:

  • AirMax, University of Texas at Austin
  • BeadBlocker, University of Houston
  • Carvis Energy Solutions, Texas A&M University
  • Coflux Purification, Rice University
  • Solidec, Rice University

Solidec, which is working on a platform to produce chemicals from captured carbon, won first place and $25,000. The company also recently scored a $100,000 grant from Rice's One Small Step Grant program, as well as a voucher from the DOE. Coflux Purification, which has a technology that destroys PFAS in filtration, won second place and$15,000. The company also secured a One Small Step Grant to the tune of $80,000. AirMax, which focuses on optimizing sustainability for air conditioning equipment, won third place and $10,000.

Last year, Houston-based Helix Earth Technologies took home the top TEX-E price and $25,000 cash awards. The venture, founded by Rawand Rasheed and Brad Husick from Rice University, developed high-speed, high-efficiency filter systems derived from technology originating at NASA.

The rest of the companies that pitched competed for non-monetary awards. Here's what companies won:

  • Group A (CCUS, oilfield solutions, analytics and minerals):
    • First place: Ardent
    • Second place: Vaulted Deep
    • Third place: Mitico
  • Group B (batteries, renewables, water, and grid technology):
    • First place: SungreenH2
    • Second place: FeX Energy
    • Third place: Mercurius Biorefining
  • Group C (Mobility, Materials, and hydrogen solutions)
    • First place: Thiozen
    • Second place: Power2Hydrogen
    • Third place: Arolytics
HETI, Rice Alliance, and TEX-E celebrated the winners at a private reception on Wednesday evening.
The Rice Alliance for Technology and Entrepreneurship identified eight startups that are best suited for disrupting energy tech and innovation. Photo courtesy of Rice Alliance

Rice Alliance pitch event identifies 8 most-promising energy tech startups

ones to watch

In honor of CERAWeek, the Rice Alliance for Technology and Entrepreneurship hosted its annual Energy Venture Day.

After over 50 startup pitches and more than 300 meetings, venture investors identified eight startups that are the most-promising companies on a path to innovate and disrupt the energy ecosystem.

The 2023 Energy Venture Day's Most-Promising Startup winners were:

AeroShield Materials

Graphic via aeroshield.tech

Hyde Park, Massachusetts-based AeroShield Materials is creating thermally insulating transparent inserts. The inserts are only four millimeters of AeroShield's material and, when placed inside a double-pane window, provides 65 percent more energy efficiency.

Columbia Power Technologies (C-Power)

Image via cpower.co

C-Power, based in Charlottesville, Virgina, has a technology that harnesses the power of the ocean.

"C-Power delivers this renewable energy resource to the world, both through low-power solutions that bring energy and the cloud to the sea and large-scale solutions that help decarbonize terrestrial grids," the company's website reads.

EarthEn

Graphic via earthen.energy

Chandler, Arizona-based EarthEn is focused on long duration energy storage solutions that use CO2 in a closed loop to store 4 to 100 hours of energy at a low cost. The SaaS tools — with artificial intelligence and machine learning — optimize peak demand pricing and use predictive analysis to enable grid resiliency.

Group1

Photo via Twitter

Group 1, based in Austin, is focused on the commercialization of potassium-ion batteries. The core technology originates from the labs of University of Texas at Austin professor JB Goodenough, co-inventor of the lithium-ion battery.

Ionada Carbon Solutions

Photo via ionada.com

Houston-based Ionada, a member of Halliburton Labs, has created a technology that can remove up to 99 percent of the carbon dioxide emissions for the energy, marine, and e-fuels, according to the company.

"Our engineers have more than a century of combined expertise in reducing emissions for the power generation, chemical, road, rail, air and marine industries. We are here to help you find the best sustainable solution to reduce your emissions," reads the website.

H Quest Vanguard

Photo courtesy of Halliburton

Another Halliburton Labs member H Quest Vanguard, headquartered in Pittsburgh, has developed an electrically powered chemical conversion platform that leverages Microwave Plasma Pyrolysis to liberate zero-CO2 hydrogen from natural gas using only a quarter of energy required by electrolysis, while coproducing a high-value carbon or petrochemical coproduct.

Pressure Corp

Photo by Anton Petrus/Getty

Houston-based Pressure Corp is developing waste pressure power systems to help midstream gas companies solve how they reduce emissions by providing the technology, capital and expertise required to achieve their environmental, social and governance goals.

STARS Technology

Photo via starsh2.com

Based in Richland, Washington, STARS Technology Corp. is commercializing advanced micro-channel chemical process technology that originally was designed for NASA and the Department of Energy. The company's reactors and heat exchangers are compact, energy-efficient, and more.

Here's what interactive, virtual events to log on to this month. Getty Images

10+ can't-miss virtual business and innovation events in Houston for May

Where to be online

While some things in Houston are starting to open back up, society hasn't yet established a timeline for when groups of more than 10 people will be allowed to safely gather. But, the programming must go on.

With that in mind, here are over 10 Houston innovation events you can attend virtually via online meetings. Be sure to register in advance, as most will send an access link ahead of the events.

May 4: Post-COVID Fund: Venture Investing in the Post-COVID World

Join Alumni Ventures Group for a webinar that explores how changes resulting from the COVID-19 pandemic will create profound change—as well as unique opportunities for new ventures that tackle these challenges.

Details: The event is at 3 p.m. on Monday, May 4. Learn more.

May 5 — Sell Your Science: Developing a Non-Confidential Pitch for in Person and Virtual Presentations

Learn tricks in preparing a non-confidential pitch deck along with tips that are aimed to help you sell your science at in person meetings or virtually.

Details: The event is at 11 a.m. on Tuesday, May 5. Learn more.

May 6 — Impacting Public Health: How Can My Idea Be A Part of the Solution?


When a pandemic hits, as a start-up company you may find that your technology can be aligned to help. However, now your timeline is expedited with a global health emergency and you need to get your technology into the market. How do you start to connect with the right players to get your technology into the U.S. market to make an impact on public health safety and security?

Details: The event is at 1 p.m. on Wednesday, May 6. Learn more.

May 6 — Virtual Event with Cindy Eckert - Expert Entrepreneur with Over $1B Exits

Cindy Eckert is an expert entrepreneur with over $1B in Exits, CEO of Sprout Pharmaceutical, and Founder of The Pink Ceiling. Attend the virtual fireside chat between Cindy Eckert and Femtech Focus founder Dr. Brittany Barreto.

Details: The event is at 2 p.m. on Wednesday, May 6. Learn more.

May 6 — Curious About Starting a Career in Tech?

One thing we know is that web developers come from different backgrounds. From teaching to consulting, design to accounting, and they're here to tell you about making that transition. Hear from professional developers in the field about how their careers lead them what they're working on now, how they got there, and how their past experiences apply to the work they do currently. Join General Assembly if you are curious about starting a career in tech, but not sure exactly where to begin.

Details: The event is at 6 p.m. on Wednesday, May 6. Learn more.

May 7 — Rice Alliance Energy Tech Venture Day

Originally scheduled to be hosted at OTC, Rice Alliance Energy Venture Day will now be a virtual event to allow startups to connect with investors and energy companies. The event will showcase about 40 promising energy technology companies. These companies have initial funding and are seeking their A, B, C, or later rounds with technology validation, field trial experience, and/or initial company revenue. The event offers a great opportunity for viewers to learn more about innovative technologies and provides companies with access to potential partners and investment opportunities.

Details: The event is at 9 a.m. on Thursday, May 7. Learn more.

May 8 — Lunch & Learn: Startup Funding Rounds

Seemingly every company wants to raise venture capital, but few founders are equipped to navigate the tangled mess of rounds, investment types, and investor expectations. At the end of this presentation, you will have a better handle on whether venture capital is right for your business and what it'll take to navigate from angels to exit.

Details: The event is at 11:30 a.m. on Friday, May 8. Learn more.

May 12 — Lunch and Learn with Asian Pacific American Entrepreneurs

According to New American Economy, Asian Pacific American entrepreneurs account for nearly a million of our nation's businesses. Whether it's apps, restaurants, social services, or consumer products, it's obvious that the entrepreneurial spirit is high in our nation. Let's hear it from our AAPI small business owners who will walk us through the triumphs and challenges they've faced while running their business and how they're making it work during a shaky period.

Details: The event is at noon on Tuesday, May 12. Learn more.

May 13-14 — 2020 Texas A&M New Ventures Competition

TNVC 2020 will be entirely virtual this year. This event is the culmination of a yearlong effort to identify and provide support to Texas-best technology ventures. There will be several private semi-finals judging rounds on May 13, with an Entrepreneurial Perspectives panel and Q&A with past winners and successful entrepreneurs. The finals will be on the 14th, followed by elevator pitches and an awards ceremony, all of which are open to the entire audience.

Details: The event is on Wednesday, May 14, and Thursday, May15. Learn more.

May 15 — How to Land a Job at a Tech Startup

Join General Assembly for this online event where a panel of tech startup talent acquisition professionals will take you through what types of opportunities exist in today's talent market, how the experience at a startup will make you more marketable in the long run, what talent acquisition professionals are actually thinking while reading resumes, advice for remote interviewing, and more.

Details: The event is at noon on Friday, May 15. Learn more.

May 29 — Mothers in Tech Breakfast

In celebration of Mother's Day, join General Assembly for a virtual breakfast featuring hard-working mothers that are also succeeding in their respective industries. A few incredible mothers will share their insights on how they reached their level of success, advice on navigating the workplace as a working mom, and how we can help the next generation of mothers in tech. Get ready for an honest, vulnerable, and insightful conversation.

    Details: The event is at 10 a.m. on Friday, May 29. Learn more.

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    Greentown Labs names Lawson Gow as its new Houston leader

    head of hou

    Greentown Labs has named Lawson Gow as its Head of Houston.

    Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. He also recently served as managing partner at Houston-based investment and advisory firm Helium Capital. Gow is the son of David Gow, founder of Energy Capital's parent company, Gow Media.

    According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role.

    “I couldn’t be more excited to join Greentown at this critical moment for the energy transition,” Gow said in a news release. “Greentown has a fantastic track record of supporting entrepreneurs in Houston, Boston, and beyond, and I am eager to keep advancing our mission in the energy transition capital of the world.”

    Gow has also held analyst, strategy and advising roles since graduating from Rice University.

    “We are thrilled to welcome Lawson to our leadership team,” Georgina Campbell Flatter, CEO of Greentown Labs, added in the release. “Lawson has spent his career building community and championing entrepreneurs, and we look forward to him deepening Greentown’s support of climate and energy startups as our Head of Houston.”

    Gow is the latest addition to a series of new hires at Greentown Labs following a leadership shakeup.

    Flatter was named as the organization's new CEO in February, replacing Kevin Dutt, Greentown’s interim CEO, who replaced Kevin Knobloch after he announced that he would step down in July 2024 after less than a year in the role.

    Greentown also named Naheed Malik its new CFO in January.

    Timmeko Moore Love was named the first Houston general manager and senior vice president of Greentown Labs. According to LinkedIn, she left the role in January.

    ---

    This article originally appeared on our sister site, EnergyCapitalHTX.com.

    Houston foundation grants $27M to support Texas chemistry research

    fresh funding

    Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

    According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

    • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
    • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
    • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

    Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

    The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

    Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

    “Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

    New Houston biotech co. developing capsules for hard-to-treat tumors

    biotech breakthroughs

    Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

    Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

    The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

    This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

    From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

    “They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

    Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

    “We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

    When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

    “This isn’t just another cell therapy,” Chakrabarti says.

    "Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.