10+ can't-miss Houston business and innovation events for September

Where to be

Here's your one-stop shop for innovation events in Houston in September. Getty Images

The busy fall event season is kicking off this month with tons of Houston innovation pitch events, educational panels, and networking opportunities.

If you know of innovation-focused events for this month or next, email me at natalie@innovationmap.com with the details and subscribe to our daily newsletter that sends fresh stories straight to your inboxes every morning.


September 5 — MassChallenge Texas in Houston Finale and Startup Showcase

The top startups from the inaugural MassChallenge Texas cohort in Houston will be recognized by community leaders to a room full of potential investors and customers, MassChallenge mentors, VIP community leaders, and their loved ones.

Details: The event is from 6 to 8 pm on Thursday, September 5, at House of Blues Houston (1204 Caroline St.). Learn more.

September 5 — Frost Bank: Fail Forward Series

Join Impact Hub Houston for an evening of #FailForward — behind-the-scenes stories straight from entrepreneurs on the challenges they faced trying to access and raise funding for their small business or startups. And, learn from bankers and financial experts what those entrepreneurs could have done to make their journey easier and more successful.

Details: The event is from 6 to 8 pm on Thursday, September 5, at BakerRipley Leonel Castillo Community Center (2101 South Street). Learn more.

September 6 — Finding your Product-Market fit via the W3 method

Amos Schwartzfarb, Author of Sell More Faster - The Ultimate Sales Playbook for Startups and Managing Director of Techstars Austin will deliver a hands-on workshop for founders (seed through Series A) that will enable you to identify the path to achieving product-market fit. Included in the $25 workshop is a signed copy of Sell More Faster.

Details: The event is from 11 am to 12:30 pm on Friday, September 6, at WeWork Labs (708 Main St., 3rd floor). Learn more.

September 10 — Founder Institute's inaugural cohort graduation showcase

The fresh (and first) graduates of the Founder Institute in Houston are celebrating the completion of their program. The graduation celebration will consist of a leadership focused commencement speech, hearing from the graduates (remarks and pitch), and showcase where each company will have a display table and be able to be speak one-on-one.

Details: The event is from 6 to 9 pm on Tuesday, September 10, at Station Houston (1301 Fannin Street, #2440). Learn more.

September 11 — Energy and Clean Technology Venture Forum XVII

The Rice Alliance's Energy and Clean Technology Venture Forum is the largest energy and clean technology venture capital conference in the U.S. open, to all emerging energy technology companies (both traditional energy and alternative energy).

Details: The event is from 8:30 am to 5 pm on Wednesday, September 11, at Jones Graduate School of Business (Rice University, 1900 Rice Blvd.). Learn more.

September 12 — HX Capital Summit 2019: Presented by JPMorgan Chase

Join Houston Exponential for its 2nd Annual Capital Summit, which will focus on the latest activity amongst Houston investments. This one-day event will highlight panel discussions from all aspects of Houston's innovation scene.

Details: The event is from 7:30 am to 3 pm on Thursday, September 12, at the Shell Auditorium (Rice University). Learn more.

September 12 — Cooley x JLABS @ TMC: Medtech Startup Fundamentals

Join Cooley, JLABS, and TMC Innovation for a half-day seminar gathering leading executives, investors, entrepreneurs, and thought leaders in the medical technology industry. Speakers will explore market trends and share strategies on how to position your startup for growth and success.

Details: The event is from 12:30 to 5:30 pm on Thursday, September 12, at the JLABS @ TMC (2450 Holcombe Blvd). Learn more.

September 17 — Raising Capital with Investment Crowdfunding

Station Houston, NextSeed, and the Greater Houston Black Chamber of Commerce are putting on a discussion about fundraising online.

Details: The event is from 11:30 am to 1:30 pm on Tuesday, September 17, at Station Houston (1301 Fannin Street, #2440). Learn more.

September 19 — The Cannon Grand Opening

The Cannon, an entrepreneurial hub in West Houston, is celebrating its new digs. Join the party to learn about coworking at The Cannon, to network with Houston's innovation ecosystem, and more.

Details: The event is from 4 to 9 pm on Thursday, September 19, at The Cannon (1336 Brittmoore Road). Invite only.

September 19 — JLABS x UH: Startup Pains: From Academia to Startup

JLABS and the University of Houston Technology Bridge present a special installment of the university's monthly Startup Pains. This month the focus is on licensing and technology transfer.

Details: The event is from 5:30 to 7 pm on Thursday, September 19, at the JLABS @ TMC (2450 Holcombe Blvd). Learn more.

September 24 — The Future of Payments: How Fintech, Crypto, and Blockchain are Transforming E-Commerce

The global economy is powered by 125 million business and payments between those businesses transacted over a variety of technologies. In the US, $2 trillion of the $58 trillion in payments generated by small business are "other" — new digital payment technologies including cryptocurrency and blockchain created by fintechs, banks and large players like Facebook and JP Morgan. Over time, the remaining $56 trillion will shift from paper checks to more digital forms. A change in the payments landscape is imminent, and in many ways, the US is behind in digital acceptance. What will this change look like? Join Vinay Pai, senior vice president of engineering at Bill.com, as he discusses.

Details: The event is from 4 to 5 pm on Tuesday, September 24, at Duncan Hall (Rice University). Learn more.

September 24 — The Eco-System of the Language Industry: Panel and Networking Event

Introducing the first Women in Localization Texas Chapter Houston Event. Winnie Heh, associate chapter manger - mentoring for the Silicon Valley Chapter, and Middlebury Institute of International Studies Career Advisor, Translation, Interpretation & Localization Management, will be presenting on importance of localization and various localization job functions available in our rapidly globalized world.

Details: The event is from 6 to 8 pm on Tuesday, September 24, at Station Houston (1301 Fannin Street, #2440). Learn more.

September 24 & 25 — Innovation Engineering Quick Start Class

Bruce G. Hall, CEO and president of eureka! inventing is teaching an abridged version of his innovation engineering course that's offered at the University of Houston. InnovationMap readers can get half off by registering through this link.

Details: The course is on either Tuesday, September 24, or Wednesday, September 25, at Energy Corridor Marriott (16011 Katy Fwy).Learn more.

September 25 — Third Coast Innovators Mixer

Calling all innovators and entrepreneurs in the Third Coast. JLABS @ TMC is hosting a networking event with fellow innovators and entrepreneurs in the ecosystem as well as current JLABS residents and the JLABS @ TMC team.

Details: The event is from 5 to 7 pm on Wednesday, September 25, at the JLABS @ TMC (2450 Holcombe Blvd). Learn more.

September 25 — Energy Tech Night

Energy Tech Night offers insights from energy digitalization/innovation/emerging tech experts and rapid-fire pitches from the cutting edge in startups offering solutions for the energy challenges of today & tomorrow.

Details: The event is from 6:30 to 8:30 pm on Wednesday, September 25, at Saint Arnold Brewery (2000 Lyons Ave) Learn More

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Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

Houston booms as No. 2 U.S. metro for new home construction

Construction Boom

Driven by population growth, more residential rooftops are popping up across Houston and the rest of Texas than anywhere else in America.

Using data from the U.S. Census Bureau and Zillow, Construction Coverage found 65,747 new residential units were authorized in greater Houston in 2024. That figure landed Houston in second place among major metro areas for the total number of housing permits, including those for single-family homes, apartments, and condos.

Just ahead of Houston was the Dallas-Fort Worth Metroplex, which took first place with 71,788 residential permits approved in 2024. In third place was the country’s largest metro, New York City (57,929 permits).Elsewhere in Texas, the Austin metro ranked sixth (32,294 permits), and the San Antonio metro ranked 20th (14,857 permits).

Construction Coverage also sorted major metro areas based on the number of new housing units authorized per 1,000 existing homes in 2024. Raleigh, North Carolina, held the No. 1 spot (28.8 permits per 1,000 existing homes), followed by Austin at No. 2 (28.6), DFW at No. 3 (22.2), Houston at No. 4 (21.6), and San Antonio at No. 13 (13.6).

A Newsweek analysis of Census Bureau data shows building permits for 225,756 new residential units were approved in 2024 in Texas — a trend fueled largely by activity in DFW, Houston, Austin, and San Antonio. That put Texas atop the list of states building the most residential units for the year.

Through the first eight months of last year, 145,901 permits for new residential units were approved in Texas, according to Census Bureau data. That’s nearly 80,000 permits shy of the 2024 total.

Among the states, Construction Coverage ranks Texas sixth for the number of residential building permits approved in 2024 per 1,000 existing homes (17.9).

Extra housing is being built in Texas to meet demand spurred by population growth. From April 2020 to July 2024, the state’s population increased 7.3 percent, the Census Bureau says.

While builders are busy constructing new housing in Texas, they’re not necessarily profiting a lot from homebuilding activity.

“Market conditions remain challenging, with two-thirds of builders reporting they are offering incentives to move buyers off the fence,” North Carolina homebuilder Buddy Hughes, chairman of the National Association of Home Builders, said in a December news release. “Meanwhile, builders are contending with rising material and labor prices, as tariffs are having serious repercussions on construction costs.”

5+ must-know application deadlines for Houston innovators

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Editor's note: As 2026 ramps up, the Houston innovation scene is looking for the latest groups of innovative startups that'll make an impact. A number of accelerators and competitions have opened applications. Read below to see which might be a good fit for you or your venture. And take careful note of the deadlines. Please note: this article may be updated to include additional information and programs.

Did we miss an accelerator or competition accepting applications? Email innoeditor@innovationmap.com for editorial consideration.

2026 HCC Business Plan Competition

Deadline: Jan. 26

Details: HCC’s annual Business Plan Competition (BPC) is an opportunity for proposed, startup and existing entrepreneurs to develop focused plans to start or grow their businesses. Accepted teams will be announced and training will begin in late February and run through early June, with six free, three-hour training sessions. Advising will be provided to each accepted team. Applicants can apply as a team of up to five persons. Finalists will present to to gudges on May 27, 2026. Last year, $26,000 was awarded in seed money to the top five teams. In-kind prizes were also awarded to all graduating teams including free products, services and memberships, with an estimated in-kind value totaling $147,000. Find more information here.

University of Houston Technology Bridge Innov8 Hub (Spring 2026)

Deadline: Jan . 30

Details: UHTB Innov8 Hub’s immersive, 12-week startup acceleration program designed to help early-stage founders launch and scale their technology startups. Selected participants will gain access to expert mentors and advisors, collaborate with a cohort of peers, and compete for cash prizes during our final pitch event. The cohort begins Feb. 16, 2026. The program culminates in Pitch Day, where participants present their ventures to an audience of investors and partners from across the UH innovation ecosystem. Find more information here.

Rice Business Plan Competition 2026

Deadline: Jan. 31

Details: The Rice Business Plan Competition, hosted by the Rice Alliance for Technology and Entrepreneurship, gives collegiate entrepreneurs real-world experience to pitch their startups, enhance their business strategy and learn what it takes to launch a successful company. Forty-two teams will compete for more than $1 million in cash, investments and prizes on April 9-11, 2026. Find more information here.

Rice Veterans Business Battle 2026

Deadline: Jan. 31

Details: The Rice Veterans Business Battle is one of the nation’s largest pitch competitions for veteran-led startups, providing founders with mentorship, exposure to investors and the opportunity to compete for non-dilutive cash prizes. The event has led to more than $10 million of investments since it began in 2015. Teams will compete April 8-9, 2026. Find more information here.

TEX-E Fellows Application 2026-2027

Deadline: Feb. 10

Details: The TEX‑E Fellowship is a hands-on program designed for students interested in energy, climate, and entrepreneurship across Texas. It connects participants with industry mentors, startup founders, investors and academic leaders while providing practical, "real-world" experience in customer discovery, business modeling, and energy-transition innovation. Fellows gain access to workshops, real-world projects, and a statewide network shaping the future of energy and climate solutions. Participants must be a student at PVAMU, UH, UT Austin, Rice University, MIT or Texas A&M. Find more information here.

2026 Energy Venture Day & Pitch Competition

Deadline: Feb. 13

Details: The Rice Alliance, the Houston Energy Transition Initiative (HETI) and TEX-E will present the annual Energy Venture Day and Pitch Competition during CERAWeek on March 24-25, 2026. Energy Venture Day features two days of presentations by energy tech ventures driving efficiency and advancements toward the energy transition. On March 24, the Pitch Preview at the Ion will feature over 50 companies presenting in front of Rice Alliance's robust network of investors and industry partners. On March 25, the Energy Venture Day and Pitch Competition during CERAWeek will showcase 36 ventures at the George R Brown Convention Center. The pitch competition is divided up into the TEX-E university track, in which Texas student-led energy startups compete for $50,000 in cash prizes, and the industry ventures track. The industry track is subdivided into three additional tracks, spanning materials to clean energy. The top three companies from each industry track will be named. The winner of the CERAWeek competition will also have the chance to advance and compete for the $1 million investment prize at the Startup World Cup. Find more information here.

Greentown Go Make 2026

Deadline: March 10

Details: Greentown Go Make 2026 is an open-innovation program with Shell and Technip Energies. The six-month program is advancing industrial decarbonization by accelerating catalytic innovations. Selected startups will gain access to a structured platform to engage leadership from Shell and Technip Energies and explore potential partnership outcomes, including pilots and demonstrations. They’ll also receive networking opportunities, partnership-focused programming, and marketing visibility throughout the program. The cohort will be selected in May. Find more information here.

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