HVAC innovation has a huge role to play in Houston amid energy transition

guest column

By prioritizing the deployment of smart, energy-efficient technologies, we can ensure that Houston remains at the forefront of the global energy landscape, setting the standard for other cities to follow. Photo via Getty Images

As Houston, the energy capital of the world, navigates the global energy transition, the city is uniquely positioned to lead by example. This transition isn’t just about shifting from fossil fuels to renewable energy; it’s about creating an ecosystem where corporations, research institutions, startups, and investors collaborate to develop and implement innovative technologies.

One of the most promising areas for reducing energy consumption and minimizing environmental impact is in heating, ventilation, and air conditioning, or HVAC, systems.

Houston’s intense weather patterns demand efficient and adaptable climate control solutions. Traditional HVAC systems, while effective in maintaining indoor comfort, often operate on fixed settings that don’t account for real-time changes in occupancy or weather. This results in energy waste and increased utility costs — issues that can be mitigated by integrating artificial intelligence into HVAC systems.

AI-driven HVAC systems offer a dynamic approach to heating and cooling, learning from user preferences and environmental conditions to optimize performance. These systems use advanced algorithms to continuously adjust their operation, ensuring that energy is used only when and where it’s needed. This results in up to 30 percent greater energy efficiency compared to conventional systems, translating into significant savings for consumers and a reduction in overall energy demand.

For a city like Houston, where energy consumption is a critical concern, the widespread adoption of AI-integrated HVAC systems could have a substantial impact. By optimizing energy use in homes, offices, and industrial spaces, these systems help reduce the strain on the electrical grid, particularly during peak usage times. Additionally, they contribute to lowering greenhouse gas emissions, aligning with Houston’s broader sustainability goals.

The potential of AI in HVAC systems extends beyond efficiency and environmental benefits. These systems enhance the user experience by offering precise control over indoor climates, adapting to individual preferences, and responding to external conditions in real-time. This level of customization not only improves comfort but also supports a smarter, more sustainable approach to energy management.

Houston’s energy transition requires the collective efforts of all sectors. While large corporations and government entities play a significant role, the contributions of startups, research institutions, and energy service companies are equally important. These entities are at the forefront of developing technologies that address both the economic and environmental challenges of our time. Investors are increasingly recognizing the value of funding solutions that offer long-term sustainability alongside financial returns, further driving the adoption of innovative energy technologies.

The integration of AI into HVAC systems represents a crucial step forward in this journey. As Houston continues to evolve as a leader in energy innovation, embracing advanced technologies like AI-driven HVAC systems will be key to achieving a more sustainable and resilient energy future. These systems are not just a technological advancement—they are a strategic tool in the broader effort to reduce energy consumption, lower emissions, and create a healthier environment for all.

At the heart of Houston’s energy transition is the commitment to building a future that balances growth with sustainability. By prioritizing the deployment of smart, energy-efficient technologies, we can ensure that Houston remains at the forefront of the global energy landscape, setting the standard for other cities to follow. As we move forward, the integration of AI into our energy infrastructure, particularly in HVAC systems, will be instrumental in shaping a sustainable and prosperous future for Houston and beyond.

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Trevor Schick is the president of KOVA, a Texas company creating sustainable solutions in building development.

This article originally ran on EnergyCapital.
Houston is in the running to receive millions from a program from the National Science Foundation. Photo via Getty Images

Houston named semifinalist for major energy transition funding opportunity

making moves

The National Science Foundation announced 34 semifinalists for a regional innovation program that will deploy up to $160 million in federal funding over the next 10 years. Among the list of potential regions to receive this influx of capital is Houston.

The Greater Houston Partnership and the Houston Energy Transition Initiative developed the application for the NSF Regional Innovation Engine competition in collaboration with economic, civic, and educational leaders from across the city and five regional universities, including the University of Houston, The University of Texas at Austin, Texas Southern University, Rice University, and Texas A&M University.

The proposed project for Houston — called the Accelerating Carbon-Neutral Technologies and Policies for Energy Transition, or ACT, Engine — emphasizes developing sustainable and equitable opportunities for innovators and entrepreneurs while also pursuing sustainable and equitable energy access for all.

“The ACT Engine will leverage our diverse energy innovation ecosystem and talent, creating a true competitive advantage for existing and new energy companies across our region," says Jane Stricker, senior vice president of energy transition and executive director for HETI, in a statement. "Texas is leading the way in nearly every energy and energy transition solution, and this Engine can catalyze our region’s continued growth in low-carbon technology development and deployment."

If Houston's proposal is selected as a finalist, it could receive up to $160 million over 10 years. The final list of NSF Engines awards is expected this fall, and, according to a release, each awardee will initially receiving about $15 million for the first two years.

"Each of these NSF Engines semifinalists represents an emerging hub of innovation and lends their talents and resources to form the fabric of NSF's vision to create opportunities everywhere and enable innovation anywhere," NSF Director Sethuraman Panchanathan says in a news release. "These teams will spring ideas, talent, pathways and resources to create vibrant innovation ecosystems all across our nation."

The NSF selected its 34 semifinalists from 188 original applicants, and the next step for Houston is a virtual site visit that will assess competitive advantages, budget and resource plans for R&D and workforce development, and the proposed leadership’s ability to mobilize plans into action over the first two years.

"Houston is poised, like no other city, to lead the energy transition. The ACT Engine presents a remarkable opportunity to not only leverage the region's unparalleled energy resources and expertise but also harness our can-do spirit. Houston has a proven track record of embracing challenges and finding innovative solutions,” says Renu Khator, president of the University of Houston, in the statement. “Through the collaborative efforts facilitated by the ACT Engine, I am confident that we can make significant strides towards creating a sustainable future that harmonizes economic growth, environmental protection and social equity."

NSF Engines will announce awards this fall after a round of in-person interviews of finalists named in July. With Houston's track record for building thriving industry hubs in energy, health care, aerospace, and the culinary arts, the region is eager to establish the next generation of leaders and dreamers responding to some of the greatest economic and societal challenges ever seen in America.

“Our energy innovation ecosystem is inclusive, dynamic, and fast growing," says Barbara Burger, energy transition adviser and former Chevron executive, in the release. "The ACT Engine has the potential to increase the amount of innovation coming into the ecosystem and the capabilities available to scale technologies needed in the energy transition. I am confident that the members of the ecosystem — incubators, accelerators, investors, universities, and corporates — are ready for the challenge that the ACT Engine will provide."

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This article originally ran on EnergyCapital.

According to a new report, the existing energy infrastructure of Texas makes it a great spot to lead the development of the hydrogen economy. Photo via Getty Images

Report: Texas is the best place to lead hydrogen economy

as the experts say

All signs point to Texas leading the development of a hydrogen market, says one new report out of Rice University.

The Baker Institute for Public Policy released a new report this week about the hydrogen economy and the role Texas will play in it. According to the experts, Texas’ legacy energy industry — as well as its geology — makes it an ideal hub for hydrogen as an energy source. Ken Medlock, senior director of the Baker Institute’s Center for Energy Studies, and Shih Yu (Elsie) Hung, research manager at the center, wrote the report.

“Texas is in a very advantageous position to play a leading role in driving hydrogen market growth, but the evolution of policy and market structure will dictate whether or not this comes to pass,” write the co-authors.

Medlock and Hung make the case for hydrogen's impact on the energy transition in the report.

“It can be produced in a number of different ways — including steam-methane reforming, electrolysis and pyrolysis — so it can leverage a variety of comparative advantages across regions,” they write.

The report explains that — with the state's existing and robust oil and gas infrastructure — Texas is the best spot to affordably develop hydrogen while managing economic challenges. Plus, Texas's coastal geology is an advantageous spot for storage and transport.

One factor to be determined, write the authors, is whether or not the policy will support the industry's growth.

“(Hydrogen’s) expansion as an energy carrier beyond its traditional uses in industrial applications will depend heavily on significant investment in infrastructure and well-designed market structures with appropriate regulatory architectures,” they write. “A lack of either will risk coordination failure along hydrogen supply chains and, thus, threaten to derail any momentum that may currently be building.”

GTI Energy and The Cynthia and George Mitchell Foundation funded this report.

Last summer, the Center for Houston's Future reported how Houston-based assets can be leveraged to lead a global clean hydrogen innovation. The Houston region already produces and consumes a third of the nation’s hydrogen, according to the report, and has more than 50 percent of the country’s dedicated hydrogen pipelines. These assets can be utilized to accelerate a transition to clean hydrogen, and the report lays out how.

"Using this roadmap as a guide and with Houston’s energy sector at the lead, we are ready to create a new clean hydrogen economy that will help fight climate change as it creates jobs and economic growth,” says Center for Houston’s Future CEO Brett Perlman. “We are more than ready, able and willing to take on these goals, as our record of overwhelming success in energy innovation and new market development shows.”

The energy industry is finally prioritizing new technology and greener energy — both in light of and in spite of a global pandemic. Photo via Getty Images

Overheard: Here’s what these energy VCs think of the pandemic’s effect on the energy transition

eavesdropping online

In a lot of ways, venture capital firms are tasked with predicting the future. They put money into tech and business services that are going to disrupt the status quo, and energy VCs are tasked with taking bets on the energy transition.

At a virtual event as a part of the 18th annual Rice Alliance Energy Tech Venture Forum, which is taking place online this week, a group of panelists moderated by Sandy Guitar, managing partner at the HX Venture Fund, discussed how the pandemic has affected the energy transition. The group of experts talked about the future of work, decarbonization, and more.

If you missed the event, here are a few key moments from the discussion.

“The role of digitization is going to be huge. The pandemic really exacerbated just how far oil and gas had been behind in that.”

— Sean Ebert, partner at Altira. Ebert explains that when times are good for energy companies, it's hard to get the attention of executives to introduce new technologies. Now, corporations are having to invest in tech that allows their employees to be mobile and remote.

“There’s never been a better time to invest in energy technology. … We are at a point where we can get the type of returns [we look for.]”

— George Coyle, managing partner at Energy Innovation Capital. Coyle adds that he's seen the pandemic effect major growth opportunities in energy startups in his portfolio.

“What we have is a sense of urgency that didn’t exist 15 years ago. Public companies virtually all have a sustainability report and need to show some sort of progress."

— Cory Steffek, managing director at Ara Partners. He adds, "I really think the opportunity in the near term is de-risking software or hardware technologies and showing people that you can construct assets where they can deploy substantial amounts of capital profitably. If you have that, from a returns standpoint, you have something that should generate significant yield."

“The part we have been focused on is how can you make the conventional more efficient, so energy-on-energy conversion is even better.”

— Hossam Elbadawy, managing director at SCF Ventures and technology partner at SCF Partners. He's referring to the question of whether to prioritize new low-carbon innovations or to make conventional methods more sustainable. His observation is that the solution is going to be a hybrid of both.

“When we think about the future of work, we think about what are the capabilities going to be required in the future to be able to improve operations in the field today?”

— Ricardo Angel, managing director and CEO of PIVA. Angel adds that, "a lot of activities might be replaced by AI," and he and his firm are thinking about how they can go about "developing the skills for the people who will be working with those tools."

The energy industry needs to re-evaluate its priorities for the workplace. Photo courtesy of Thomas Miller/Breitling Energy

Why Houston’s oil and gas leaders need to prioritize becoming a modern energy workplace

Guest column

The oil and gas industry today is being shaped by truly unprecedented conditions. In the face of a global economic crisis, players in this space are grappling with how best to spend and save resources in a way that's smart, deliberate and centered on expanding a company's value.

But even when the price of oil was four times what it is today, only 13 percent of the oil and gas industry's leaders said they were moving fast enough from a tech investment perspective, according to data my company, Quorum Software, pulled back in October. This was the writing on the wall that the industry was unprepared for a crisis of this magnitude, let alone two.

At the same time, there are a number of critical labor challenges that could curb Houston's oil and gas sector's ability to rebound. In order to future proof the energy industry and attract and retain young and innovative talent, Houston's oil and gas leaders need to prioritize investments in technology and start creating specific business advantages through tech.

Create a place young talent will want to land

In the Houston area, millennials age 25 to 34 make up the largest percentage of the adult population, according to the most recent data from the U.S. Census Bureau. Despite this, oil and gas has historically suffered a gap in talent for this employee subset.

As the Houston energy economy seeks to attract talent from Gen Z and millennial pools, they must invest in transformative technology and become a modern energy workplace.

In our recently released industry report, oil and gas decision makers made it clear that they understand having better technology generates more efficient workplaces. What's more, four out of five of these industry leaders think employees will leave without access to sound technology.

Technology will play as an essential part of crisis recovery, and Houston's business leaders in this sector must align their tech investments over the next two quarters in order to both drive business success and also retain and attract a rich talent pool.

Prepare for the long road ahead

Oil and gas leaders in this region are familiar with managing volatility. Prices rise and fall much more quickly than in other industries, with fluctuating regulations, border skirmishes, trade deals, weather and local and global politics all impacting an ever-changing market. We have entered a period when short-term stability and long-term success are both in jeopardy unless you innovate now – especially as the prognosis for long-term structural change in the industry indicates that things might get a lot tougher before they turn around.

In my 30-plus years in the software industry, I've heard thoughtful people talk a lot about disruption. The idea that companies use software and/or technology to disrupt both their internal operations or disrupt markets to make sure that markets don't disrupt them. In just a few months, the commodity pricing shifts have disrupted economic forces on our businesses. As much as we've talked about technology for transformation and modernization, we need to adopt strategies that allows for more agility and sustainability during big market swings.

Judging by the responses in our recent report, oil and gas decision-makers are realistic about the business challenges ahead of them and their inability to solve the problems using the technologies they have in place. Like their IT decision-maker counterparts, 95 percent of oil and gas industry leaders agree that in today's marketplace, a company that doesn't embrace technological advances will not succeed in terms of streamlining operations (land management, accounting, etc.). In fact, in oil and gas, 97 percent of respondents believe the industry will decline if it doesn't adapt to the changes around it.

The takeaway? To survive today — and thrive tomorrow — you don't need to disrupt your business, but you do need to modernize it to be agile and sustain revenue production. You need to bring new technologies into the fold to improve your efficiencies. You need to challenge the status quo, not only to help you endure today's conditions, but also get where you want to go.

This point is only unscored by recent reports that highlight how the Texas Workforce Commission is relying on tech from the 1980s as unemployment claims overwhelm the system. Across industries, and especially those experiencing the volatility that the oil and gas industry is, technology holds the key to attracting and retaining talent, streamlining operations, and staying afloat in these uncharted waters.

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Gene Austin is the CEO of Houston-based Quorum Software.

Houston — known as the Energy Capital of the World — had several trending stories in 2019 focused on energy innovation. Photo courtesy of Thomas Miller/Breitling Energy

These were Houston's top energy innovation stories this year

2019 in review

Editor's note: With 2020 just days away, InnovationMap is looking back at 2019's top stories in Houston innovation. Within the energy category, top stories included game-changing energy tech companies, the future of oil and gas — as told by the industry's emerging leaders, the results of a reverse pitch competition for ExxonMobil, and more.

Rice Alliance names the 10 most promising startups at Houston's Offshore Technology Conference

Startups from across the world pitched at the Rice Alliance Startup Roundup at the Offshore Technology Conference. Getty Images

Over 50 different startups from across the globe gathered at the Offshore Technology Conference for the fifth annual Rice Alliance Startup Roundup event. The full day of speed pitching and presentations, hosted by Rice Alliance Managing Director Brad Burke, took place at NRG Arena on Monday, May 6.

After interacting with all the various startups, the Rice Alliance's panel of experts voted on the 10 most promising startups. Half of the companies that were recognized are based in Houston — and even more have an office or some sort of operations in town. Here's which technologies the offshore oil and gas industry has its eye on. Click here to read more.

Overheard: Here's the future of oil and gas tech, according to this panel at OTC

Three young professionals took the stage to discuss the future tech of offshore operations in oil and gas. Courtesy photos

The oil and gas industry has a reputation for being a slow adapter when it comes to technology advances, but that's changing — as is the workforce. In the next few years, half of the United States workforce will be millennials, according to the Bureau of Labor Statistics.

A panel at the 2019 Offshore Technology Conference discussed the future of oil and gas technology — and the young professionals who are taking over the industry. Click here to read more.

ExxonMobil taps two new technologies in a Houston reverse pitch program

ExxonMobil named two winners in its inaugural reverse pitch competition with BBL Ventures. Courtesy of OctoRD

ExxonMobil and BBL Ventures have teamed up to flip the script on pitch competitions. Rather than have startups pitch themselves, the two companies collaborated on a reverse pitch event where Exxon identifies a few problems and search for companies that can build a solution.

The purpose of the event, says Tim Westhoven, technology scouting and venturing at ExxonMobil at the Baytown refinery, was to get the company out of its day-to-day to spark new ideas and innovation.

"Typically, as an engineer, when we think about how we solve a problem, we start inside the organization," Westhoven says at the event, which took place on Wednesday, June 5, at Station Houston. "Then we think about what problems we want to solve. Sometimes, you don't even think at all about what's available on the outside. This reverse pitch is us thinking about the impact we want to have and what the outside can offer." Click here to read more.

5 emerging energy tech companies in Houston revolutionizing the industry

It might not be surprising to discover that the energy capital of the world is a hub for energy startups. Getty Images

If you thought Houston's wildcatter days were exciting, just you wait. Houston has an emerging ecosystem of tech startups across industries — from facial recognition devices used at event check in to a drone controller that mimics movement in space.

A somewhat obvious space for Houston entrepreneurs is oil and gas. While the energy industry might have a reputation of being slow to adapt new technologies, these five Houston startups are developing the future of the industry — one device at a time. Click here to read more.

Exclusive: Plug and Play announces 15 energy tech companies for inaugural Houston cohort

Plug and Play Technology Center has named its first 15 startups in its Houston Energy and Sustainability cohort. Getty Images

A Silicon Valley accelerator program has announced the companies that will participate in its first Houston cohort just as the program begins to foster energy tech innovation in town.

Plug and Play Technology Center, which announced its entry into the Houston market this summer, named the 15 companies that will complete the program. While there are only two Houston-based companies in the mix this time around, all 15 companies will be operating locally with Houston corporate partners and startup development organizations.

"By being a part of this Plug and Play cohort, our corporate partners have validated that there is an interest in these startups' technology solutions," says Payal Patel, director of corporate partnerships for Plug and Play in Houston. "This will encourage these non-Houston based startups to spend more time in Houston, likely (and hopefully) leading to them doing business with our corporations, raising money from local investors, hiring local talent, and setting up an office in Houston." Click here to read more.

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Axiom Space expands executive team with two C-suite hires

new leaders

Fresh off officially making Texas its legal headquarters, Axiom Space has named two new C-level executives.

The Houston-based spacetech company, which is developing the first commercial space station, announced earlier this month that it had appointed Zach Gitomer as its new chief financial officer and Erick Wegerer as chief information officer.

Gitomer served as vice president of investor relations and capital markets for Axiom from March to June of this year. Before joining Axiom, he held various leadership roles at Bank of America, Merrill Lynch, and Citi, where he supported technology and growth companies, according to Axiom.

"Building era-defining space infrastructure and pioneering the orbital economy is a complex endeavor that requires not just an audacious vision and stellar engineering talent, but the financial infrastructure, discipline, and capital strategy to match," Gitomer shared in a LinkedIn post. "I’m honored to take on this role ... I’m looking forward to partnering with the exceptional leadership team here at Axiom Space during a defining chapter for the company and commercial spaceflight broadly, as well as a crucial period for maintaining U.S. human presence in low-Earth orbit and leadership in space exploration."

Wegerer joins Axiom after most recently serving as CIO of Washington-based Insitu Inc., a subsidiary of Boeing that develops customized unmanned hardware for commercial, government and defense customers.

"My time at Insitu was defined by talented people, meaningful challenges, and work that mattered. I'm grateful for the teams, partners, and leaders who made progress there possible. Stepping into Axiom, I'm energized by the mission, the momentum, and the opportunity to help shape what's next," Wegerer shared.

Photo via LinkedIn

The duo was celebrated on the floor of the New York Stock Exchange last week.

“We are pleased to welcome these exceptional leaders to the Axiom Space team," Axiom CEO Jonathan Cirtain added in the announcement. “Their strong record of helping complex organizations advance their strategic priorities will strengthen our executive team to further advance our core business objectives."

It's been a busy summer for Axiom. The company tacked on an additional $175 million to a previously announced capital raise, bringing the oversubscribed round to a total of more than $525 million, in June.

It also announced plans to open a Japanese subsidiary July 1. It tapped veteran Japanese astronaut Koichi Wakata to lead Axiom Space Japan as chief technology officer in the Asia-Pacific region. It also shared plans to establish Axiom Space Switzerland, a wholly owned subsidiary based in Lucerne that is also expected to begin operations this summer.

Axiom also officially redomiciled its legal headquarters from Delaware to Texas last month. Read more here.

Houston hardtech accelerator names 8 founders to 2026 cohort

hardtech fellows

Hardtech-focused organization Activate has named 50 new members to its 2026 cohort of scientists, which includes eight startups joining Activate Houston.

Activate aims to support scientists at "the outset of their entrepreneurial journey." It partners with U.S.-based funders and research institutions to support its fellows in developing high-impact technology. Its fellows receive a living stipend, research and development funding, connections from Activate's robust network of mentors and access to a curriculum specific to the program for two years.

This year's fellows represent 41 companies from 22 U.S. cities and 11 states.

“This cohort clearly demonstrates that the next industry-defining companies won't choose between modern technology and deep science; they'll be built by combining both,” Cyrus Wadia, CEO of Activate, said in the announcement. “These are the scientists and engineers turning our most urgent global challenges into the companies that will deliver a more sustainable future.”

The Houston fellows are working across the energy, space, AI infrastructure and agriculture sectors. They include:

  • Sophie Clare Broun, founder of Anning Corporation, which is producing clean hydrogen by stimulating naturally occurring geologic deposits
  • Kathy Andersen, founder of Brint Tech, which builds optical sensing systems that quantify hydrogen for infrastructure operators
  • Dorsa Talebi, founder of Kinetiq Drive, which builds rare-earth-free, contact-free electric motors with wireless rotors for small appliances and heavy industry alike
  • Neethu Pottackal, founder of Nivera, which is developing natural, edible coatings made from agricultural byproducts to reduce food waste and extend the shelf life of fresh food
  • Jonathan Huffman, founder of Orbital Arc, which is shrinking spacecraft propulsion to a microchip powerful enough for deep space
  • Tim Lee, founder of Renesin, which develops advanced materials for faster, more efficient AI hardware
  • Joshua Livingston, founder of Selerra Separations, which is developing high-performance membranes that cut the cost and energy consumption of water treatment
  • Wenli Jiang, founder of SwieNitro Recovery, which is developing technology that converts nitrogen-rich waste streams into valuable fertilizer

"Home to the largest concentration of engineers in the United States and a dense ecosystem of Fortune 100 and Fortune 500 companies, Houston is uniquely positioned for scientists tackling large-scale industrial challenges. Activate Houston fellows are connected to the city's deep networks in energy, chemicals, and materials," Activate said in the announcement.

Activate named its inaugural Houston cohort in 2024. It has other hubs in Boston, New York, and Berkley, California—where Activate is headquartered. The organization also offers a virtual and remote cohort, known as Activate Anywhere. Nationally, it has supported 346 fellows and 276 companies since 2015.

Activate Houston is led by managing director Jeremy Pitts, who co-founded Greentown Labs in Boston. It is based out of the Ion. The latest cohort is Activate Houston's third. Read more about the last year's cohort here.

Rice, Houston Methodist award $90K for cancer research projects

seed grants

Rice University’s Synthesis X Center, in partnership with the Houston Methodist Neal Cancer Center, announced earlier this month the organizations would award $90,000 in seed grant funding to two projects that could help fight cancer. One would ease the pain of chemotherapy, while the other could change the way the progression of leukemia is tracked.

“We’re excited to be collaborating with the Neal Cancer Center to support collaborative, novel and interdisciplinary proposals to improve cancer care and outcomes,” Han Xiao, Rice professor of chemistry and the director of the SynthX Center, said in a news release. “Together, we can achieve translational excellence.”

The projects

Chemotherapy is one of the most effective cancer treatments, but it can be hard on the body. The human body doesn’t like being injected with radioactive material, especially the skin around the injection point, which can become extremely irritated. For patients in long-term treatment, the skin irritation can be more than just a bother; it can lead to infections that are dangerous to a compromised immune system.

Angel A Marti, a professor of chemistry at Rice University, and Biana Godin, an associate professor of nanoscience at Houston Methodist Research Institute, are experimenting with metal nanoclusters as a way to block radiation at the injection site. The nanocluster could be applied in a cream or a gel on the skin, serving as a type of shield against the harsh radioactive material.

Meanwhile, Yuan Ma, an assistant professor of chemistry at Rice, and Shu-Hsia Chen, a professor of immunology at Houston Methodist Research Institute, are working with m6A. Discovered in the 1970s, m6A is the most prevalent chemical modifier found in mRNA in mammals. It is prevalent in many cancers, including leukemia.

Ma and Chen are working on measuring the amount of m6A in leukemia to see if it can determine the most effective cancer treatments. The team is also experimenting with ways to shut off m6A to see if it makes current leukemia treatments more effective.

Progress from SynthX

SynthX was first launched in April 2024 to turn research from Rice and Houston Methodist into real-world cancer treatments. Within a year, the center had secured $1.5 million in grant money to work on crossing the blood-brain barrier in brain cancer treatments. These latest awards show that SynthX Center continues to bridge the worlds of research and clinical practice.

“This collaboration reflects a shared commitment to team science in cancer research,” Daniela Matei, the director of the Houston Methodist Neal Cancer Center, added in the release. “These are the types of translational and pioneering projects that lead to transformation in patient care.”'

The SynthX Center awarded $90,000 in seed grants to three teams in 2025 and $80,000 to three teams in 2024.

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