3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Jon Lambert of The Cannon, Ken Cowan of Enchanted Rock, and Richard Wilson of the University of Houston. Photos courtesy

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes a podcast with the CEO of a community-focused coworking space, a professor joining a major health care research project, and a guest columnist with advice on navigating the energy transition.

Jon Lambert, CEO of The Cannon

Jon Lambert, CEO of The Cannon, joins the Houston Innovators Podcast to discuss the growth of The Cannon, including its newest location. Photo courtesy of The Cannon

For the past five years as CEO, Jon Lambert has faced some challenges leading The Cannon — from navigating a global pandemic to the subsequent evolved real estate market. But now, the coworking and community building company is poised for even more growth — especially with its ninth location opening up this month — thanks to its community-driven mission.

The Cannon Memorial opens its doors on Monday, May 13, with a week of free coworking and events. And while the new space, developed in partnership with MetroNational, is open for leasing, Lambert says on the Houston Innovators Podcast the first and foremost, The Cannon is a community.

"The Cannon wasn't created as a real estate play — we got into coworking because as we started supporting the community and asking the question of, 'what can we do for you?,' one of the highlights was, 'hey, we need space to work,'" he says on the show. "For us, we were going to provide space because that's one of the key needs of this community.

"Our measurement of success is not the buildings we have or the occupancy even — it's what's the success of the companies that are part of the community," he continues. Click here to read more. 


Ken Cowan, senior vice president of Enchanted Rock

Ken Cowan writes a guest column for InnovationMap. Photo courtesy

As senior vice president of Enchanted Rock, a Houston-based provider of microgrid technology, Ken Cowan has seen how energy resilience has emerged as a key strategy for businesses across industries, as he writes in a guest column for InnovationMap.

"Executives must recognize the strategic imperative of investing in resilient energy infrastructure like microgrid systems, which can provide a competitive advantage against organizations that do not have similar measures in place," he writes. "In doing so, they can navigate uncertainty with confidence, set their business up for future success, and emerge stronger and more resilient than ever before."

In the piece, he explores the value proposition and other benefits to making these changes. Click here to read more.

Richard Willson, Huffington-Woestemeyer Professor of chemical and biomolecular engineering at the University of Houston

Richard Willson (center) and his team are working to develop a mix-and-read antibody measurement system that uses fluorescent materials to determine the amount of antibody present in a sample. Photo via UH.edu

An engineering project at the University of Houston has been selected to join a $10 million effort to bring biopharmaceutical manufacturing into the future. The National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL) chose the lab of Richard Willson, Huffington-Woestemeyer Professor of chemical and biomolecular engineering at UH, as one of eight development projects that it will fund.

Willson and his team are working to develop a mix-and-read antibody measurement system that uses fluorescent materials to determine the amount of antibody present in a sample. The funding for this project is $200,000. This is the first grant UH has received from NIIMBL.

“In the course of the manufacturing processes, it's important to know the concentration of antibody in your sample and this measurement needs to be made many times in a typical manufacturing process,” said Willson in a press release. In the realm of fluorescents, he is also working to pioneer the use of glow sticks to detect biothreats for the U.S. Navy. His discoveries include a fluorescent material that emits one color of light when excited with another color of light. Click here to read more. 

Here's why more and more companies — across industries — are making the switch to sustainable technology. Photo via Getty Images

Houston expert on why companies across industries are investing in sustainable energy

guest column

In a modern business landscape characterized by increasing uncertainty and volatility, energy resilience has emerged as a cornerstone of strategic decision-making.

Let's delve deeper into why executives should view energy resilience as one of the best risk management investments they can make.

Mitigating risks and enhancing stability

Investing in energy resilience isn't solely about averting risks; it's about mitigating the potential losses that could arise from energy-related disruptions. It is estimated that half of today’s businesses lack an effective resilience strategy, even though nearly 97 percent of companies have been impacted by a critical risk event.

Whether it's power outages from extreme weather events, grid emergencies from a changing resource mix that is more weather dependent or cyber-attacks, disruptions can inflict substantial financial and reputational damage on businesses. By implementing resilient energy infrastructure and practices, organizations can minimize the impact of such disruptions, ensuring consistent operations even in the face of adversity. As an added benefit, these investments can also contribute to enhancing the stability of our grid infrastructure, benefiting not just individual businesses but the local community and the entire economy.

Improving costs and operational efficiency

Energy resilience also isn't just a defensive strategy; it's also about optimizing costs and operational efficiency to create competitive advantage. By investing in resilient energy infrastructure, such as backup power systems and microgrids, businesses can reduce the downtime associated with energy disruptions, thus avoiding revenue losses and operational inefficiencies.

Additionally, resilient energy solutions often lead to long-term cost savings through increased energy efficiency and reduced reliance on costly backup systems. As circumstances become increasingly uncertain, businesses that prioritize energy resilience can gain a competitive edge by operating more efficiently and cost-effectively than their counterparts.

Ensuring consistent operations amidst uncertainty

In today's rapidly changing business environment, characterized by geopolitical tensions, climate change, and technological advancements, uncertainty has become the new normal. Amidst this uncertainty, ensuring consistent operations is paramount for business continuity and long-term success. Investing in energy resilience provides businesses with the assurance that they can maintain operations even in the face of unforeseen challenges.

Whether it's a sudden power outage from a storm or the grid is stressed and unable to deliver reliable power, resilient energy infrastructure enables organizations to adapt swiftly and continue delivering products and services to customers without interruption.

Enhancing sustainability efforts

In recent years, a growing emphasis on sustainability and environmental stewardship has led to organizations recognizing the importance of reducing their carbon footprint and transitioning towards cleaner, renewable energy sources. Investing in energy resilience provides an opportunity to align sustainability efforts with business objectives.

By integrating renewable energy technologies and energy-efficient practices into their resilience strategies, organizations can not only enhance their environmental performance but also achieve long-term cost savings, ensure regulatory compliance, and build stakeholder trust.

The value of energy resilience for businesses

It is not enough to successfully handle day-to-day operations anymore; organizations need to be prepared for unpredictable events with a reliable energy supply and backup plan. Recently, a hospital in Texas had to evacuate patients and experienced heavy financial losses due to the failure of their traditional diesel generators during an extended outage.

After reevaluating their resiliency strategy, they decided to implement full-facility backup power using Enchanted Rock’s dual-purpose managed microgrid solution, which kept their power on during the next outage and ensured both patient safety and full operational capabilities. Investing in an energy resilience strategy like a microgrid will mitigate these risks and ensure always-on power in times of uncertainty.

A responsible decision for the greater good

Beyond the immediate benefits to individual businesses, investing in energy resilience is also a responsible decision for the greater good. As businesses become increasingly reliant on the grid infrastructure, ensuring its resilience is essential for the stability and reliability of the entire energy ecosystem. By proactively investing in resilient energy solutions, for themselves, businesses also contribute to strengthening the grid infrastructure, reducing the risk of widespread outages, and promoting the overall resilience of the energy system.

Executives must recognize the strategic imperative of investing in resilient energy infrastructure like microgrid systems, which can provide a competitive advantage against organizations that do not have similar measures in place. In doing so, they can navigate uncertainty with confidence, set their business up for future success, and emerge stronger and more resilient than ever before.

———

Ken Cowan is the senior vice president of Enchanted Rock, a Houston-based provider of microgrid technology.

This article originally ran on EnergyCapital.
Inc. magazine's 2022 Best in Business list recognizes influential and impactful companies. Photo via Getty Images

3 Houston companies rank among best in biz list

better than all the rest

In the season’s spirit of giving, Inc. magazine has named three Houston companies to its 2022 Best in Business list, recognizing companies that put purpose before profit.

The Houston honorees are:

  • Enchanted Rock, a producer of energy microgrids powered by natural gas and renewable natural gas. In a news release, Thomas McAndrew, the company’s founder and CEO, says the Inc. recognition reflects “the dedication and hard work of our employees who work tirelessly to help our customers keep their power on.”
  • Proxima Clinical Research, a contract research organization for the biotech and medtech sectors. Earlier this year, Proxima appeared on the Inc. 5000 list of the country’s fastest-growing private companies.
  • Smith, a distributor of electronic components and semiconductors. The company has undertaken several humanitarian relief efforts for Ukraine, including the donation of at least $750,000 worth of electronics to Ukrainian citizens.

Inc. says its Best in Business list recognizes “the most dynamic companies of all sizes and industries that have had an outstanding influence on their communities, their industries, the environment, or society as a whole.”

Rather than relying on criteria tied to sales or funding, Inc.’s editors reviewed companies’ achievements over the past year and focused on how they made a positive difference in the world. They then selected honorees in 55 overall categories, and in age-based, revenue-based, size-based, and impact-based categories.

In all, Inc. named 14 Texas companies to this year’s Best in Business list. Aside from the three Houston companies, they are:

  • Austin-based AlertMedia, which produces emergency communication software
  • Austin-based Halcyon, a provider of security technology
  • Austin-based Matterlab, a communications agency
  • Austin-based Pushnami, which offers an advertising and engagement platform
  • Austin-based ZenBusiness, a provider of business products and services
  • Dallas-based Upkeep Aesthetics, a franchiser of medical spas
  • Fort Worth-based TimelyMD, which delivers virtual health and well-being services for students
  • Frisco-based Lexipol, a provider of policy, training, and wellness services for the public safety sector
  • Irving-based Tricolor Holdings, which sells used cars and extends auto loans to underserved Hispanic consumers
  • Plano-based Improving, a provider of tech consulting and training
  • San Antonio-based AmeriVet Veterinary Partners, an operator of veterinary practices
Houston essentially matched Austin in venture capital funds received in the third quarter of 2018. Getty Images

Houston neck-and-neck with Austin in third quarter venture capital funding reports

It's on

It was a Texas showdown when it came to venture capital funding between Houston and Austin in the third quarter of 2018. According to Crunchbase data, Houston startups pulled in $138.8 million — 39.2 percent of the state's entire VC funding — while Austin startups reported receiving $150.6 million — 42.6 percent of the funds.

"It's something we've never even come close to before and, all of the sudden, boom, we're right there," Station Houston CEO Gabriella Rowe tells InnovationMap. "I think that's what we are going to continue to see in Houston."

"We're not going to see little wins now. We're going to start seeing big wins."

Before the startup scene can truly celebrate, it's worth noting that the entire state struggled in the third quarter. VCs contributed $353.7 million to Texas startups in 91 known deals, according to the report. That's less than half of what was reported in the second quarter, and, actually, it's less that what Austin alone received in Q2. However, the state is up year-over-year in VC funding by 11 percent, as the state only saw $319.6 million in Q3 of 2017.

Chart courtesy of Crunchbase

Crunchbase reported that the largest four funding rounds in Houston were as follows:

  • OncoResponse (immuno-oncology): $40 million in September
  • ViraCyte (biopharmaceuticals): $30 million in September
  • Enchanted Rock LLC (utilities): $23.6 million in July
  • DNAtriX (cancer treatment): $15.5 million in September
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Greentown Labs names Lawson Gow as its new Houston leader

head of hou

Greentown Labs has named Lawson Gow as its Head of Houston.

Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. He also recently served as managing partner at Houston-based investment and advisory firm Helium Capital. Gow is the son of David Gow, founder of Energy Capital's parent company, Gow Media.

According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role.

“I couldn’t be more excited to join Greentown at this critical moment for the energy transition,” Gow said in a news release. “Greentown has a fantastic track record of supporting entrepreneurs in Houston, Boston, and beyond, and I am eager to keep advancing our mission in the energy transition capital of the world.”

Gow has also held analyst, strategy and advising roles since graduating from Rice University.

“We are thrilled to welcome Lawson to our leadership team,” Georgina Campbell Flatter, CEO of Greentown Labs, added in the release. “Lawson has spent his career building community and championing entrepreneurs, and we look forward to him deepening Greentown’s support of climate and energy startups as our Head of Houston.”

Gow is the latest addition to a series of new hires at Greentown Labs following a leadership shakeup.

Flatter was named as the organization's new CEO in February, replacing Kevin Dutt, Greentown’s interim CEO, who replaced Kevin Knobloch after he announced that he would step down in July 2024 after less than a year in the role.

Greentown also named Naheed Malik its new CFO in January.

Timmeko Moore Love was named the first Houston general manager and senior vice president of Greentown Labs. According to LinkedIn, she left the role in January.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

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