These Houston-area entrepreneurs have something to celebrate this week. Photos courtesy of EY

Four entrepreneurs whose companies are in or near the Houston metro area have been named winners in Ernst & Young’s Entrepreneur Of The Year regional competition and now will head to the national competition.

Local winners of the Entrepreneur Of The Year 2022 Central South Award are:

  • Elliott Bouillion, founder and executive chairman of Bellaire-based Resource Environmental Solutions. The company helps clients with environmental mitigation, stormwater management and water quality, and climate adaptation and flood resilience.
  • Blake Brannon, founder and president of Brenham-based Brannon Industrial Group. The company buys and recycles scrap metal, provides waste and recycling services, rents out portable toilets, and offers sustainable printing services.
  • Dr. Juliet Breeze, founder and CEO of Houston-based Next Level Medical, which operates membership-model urgent care clinics.
  • Jamie Welch, president, CEO, and chief financial officer of Houston-based Kinetic Holdings, a midstream oil and natural gas operator in the Delaware Basin of West Texas and northern New Mexico.

Among the criteria used to select the regional winners were purpose, growth, impact, and entrepreneurial spirit.

“Each of these entrepreneurs has exhibited curiosity, ingenuity, and courage, and we are proud to celebrate this outstanding group of leaders and welcome them as valuable members of our Entrepreneur Of The Year community,” says Anna Tallent, co-director of the awards’ Central South program.

As regional award winners, these entrepreneurs will be considered for the Entrepreneur Of The Year 2022 national awards, which will be presented in November. The overall Entrepreneur Of The Year winner at the national level then will move on to the EY World Entrepreneur Of The Year program, which will name its top winner in June 2023.

In a news release, Breeze says she’s honored to be given such a prestigious award.

“This award is further validation that at Next Level, we are really on to something. Healthcare needs to be available to patients when and where they need it,” Breeze says.

Aside from the Houston-area winners, here are the other recipients of this year’s Entrepreneur Of The Year Central South Award:

  • CEO Amanda Baldwin and founder and Chairwoman Holly Thaggard of San Antonio-based Supergoop! The company makes and sells sunscreen-based skincare products.
  • Cory Brymer, founder and CEO of Hutto-based BryComm, a provider of technology and security infrastructure services.
  • William Chan, co-founder and CEO of Austin-based Iodine Software, a provider of AI-powered software for the healthcare industry.
  • Todd Dipaola, founder and CEO of Austin-based InMarket, which operates a platform for localized advertising.
  • Dr. David Ferguson, co-founder, president, and CEO of San Antonio-based Celebrate Dental & Braces, which has offices in five states.
  • Mark Floreani, co-founder and CEO of Austin-based FloSports, a streaming service for sporting events.
  • James Garvey, founder and CEO of Austin-based Self Financial, which offers credit-building loans.
  • Tim Heyl, founder and CEO of Austin-based Homeward, whose loans help buyers make all-cash offers for homes.
  • Joel Kocher, co-founder and CEO of Austin- based HumanN, a provider of superfood products.
  • JeVon McCormick, president and CEO of Austin-based book publisher Scribe Media.
  • Thomas Thill, CEO of San Antonio-based AmeriVet Veterinary Partners, an owner and operator of veterinary practices.
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German biotech co. to relocate to Houston thanks to $4.75M CPRIT grant

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Armed with a $4.75 million grant from the Cancer Prevention and Research Institute of Texas, a German biotech company will relocate to Houston to work on developing a cancer medicine that fights solid tumors.

Eisbach Bio is conducting a clinical trial of its EIS-12656 therapy at Houston’s MD Anderson Cancer Center. In September, the company announced its first patient had undergone EIS-12656 treatment. EIS-12656 works by suppressing cancer-related genome reorganization generated by DNA.

The funding from the cancer institute will support the second phase of the EIS-12656 trial, focusing on homologous recombination deficiency (HRD) tumors.

“HRD occurs when a cell loses its ability to repair double-strand DNA breaks, leading to genomic alterations and instability that can contribute to cancerous tumor growth,” says the institute.

HRD is a biomarker found in most advanced stages of ovarian cancer, according to Medical News Today. DNA constantly undergoes damage and repairs. One of the repair routes is the

homologous recombination repair (HRR) system.

Genetic mutations, specifically those in the BCRA1 and BCRA1 genes, cause an estimated 10 percent of cases of ovarian cancer, says Medical News Today.

The Cancer Prevention and Research Institute of Texas (CPRIT) says the Eisbach Bio funding will bolster the company’s “transformative approach to HRD tumor therapy, positioning Texas as a hub for innovative cancer treatments while expanding clinical options for HRD patients.”

The cancer institute also handed out grants to recruit several researchers to Houston:

  • $2 million to recruit Norihiro Goto from the Massachusetts Institute of Technology to MD Anderson.
  • $2 million to recruit Xufeng Chen from New York University to MD Anderson.
  • $2 million to recruit Xiangdong Lv from MD Anderson to the University of Texas Health Science Center at Houston.

In addition, the institute awarded:

  • $9,513,569 to Houston-based Marker Therapeutics for a first-phase study to develop T cell-based immunotherapy for treatment of metastatic pancreatic cancer.
  • $2,499,990 to Lewis Foxhall of MD Anderson for a colorectal cancer screening program.
  • $1,499,997 to Abigail Zamorano of the University of Texas Health Science Center at Houston for a cervical cancer screening program.
  • $1,497,342 to Jennifer Minnix of MD Anderson for a lung cancer screening program in Northeast Texas.
  • $449,929 to Roger Zoorob of the Baylor College of Medicine for early prevention of lung cancer.

On November 20, the Cancer Prevention and Research Institute granted funding of $89 million to an array of people and organizations involved in cancer prevention and research.

West Coast innovation organization unveils new location in Houston suburb to boost Texas tech ecosystem

plugging in

Leading innovation platform Plug and Play announced the opening of its new flagship Houston-area location in Sugar Land, which is its fourth location in Texas.

Plug and Play has accelerated over 2,700 startups globally last year with corporate partners that include Dell Technologies, Daikin, Microsoft, LG Chem, Shell, and Mercedes. The company’s portfolio includes PayPal, Dropbox, LendingClub, and Course Hero, with 8 percent of the portfolio valued at over $100 million.

The deal, which facilitated by the Sugar Land Office of Economic Development and Tourism, will bring a new office for the organization to Sugar Land Town Square with leasing and hiring between December and January. The official launch is slated for the first quarter of 2025, and will feature 15 startups announced on Selection Day.

"By expanding to Sugar Land, we’re creating a space where startups can access resources, build partnerships, and scale rapidly,” VP Growth Strategy at Plug and Play Sherif Saadawi says in a news release. “This location will help fuel Texas' innovation ecosystem, providing entrepreneurs with the tools and networks they need to drive real-world impact and contribute to the state’s technological and economic growth."

Plug and Play plans to hire four full-time equivalent employees and accelerate two startup batches per year. The focus will be on “smart cities,” which include energy, health, transportation, and mobility sectors. One Sugar Land City representative will serve as a board member.

“We are excited to welcome Plug and Play to Sugar Land,” Mayor of Sugar Land Joe Zimmerma adds. “This investment will help us connect with corporate contacts and experts in startups and businesses that would take us many years to reach on our own. It allows us to create a presence, attract investments and jobs to the city, and hopefully become a base of operations for some of these high-growth companies.”

The organization originally entered the Houston market in 2019 and now has locations in Bryan/College Station, Frisco, and Cedar Park in Texas.