This week's roundup of Houston innovators includes Howard Berman of Coya Therapeutics, Elad Inbar of RobotLAB, and Steve Altumus of Intuitive Machines. Photos courtesy

Editor's note: Every week, I introduce you to a handful of Houston innovators to know recently making headlines with news of innovative technology, investment activity, and more. This week's batch includes a robotics expert, a space tech leader, and a therapeutics CEO.

Howard Berman, co-founder and CEO of Coya Therapeutics

This week's episode of the Houston Innovators Podcast revisits a conversation with Howard Berman, co-founder and CEO of Coya Therapeutics. Photo courtesy of Coya

It's been a busy summer for Houston-based Coya Therapeutics, a clinical-stage biotech company that's creating revolutionary treatments for neurodegenerative diseases like Alzheimer’s, Parkinson’s, and ALS.

In July, Coya announced that has expanded its collaboration with Houston Methodist Research Institute, or HMRI. The publicly traded company also announced fresh funding from the Johnson Center for Cellular Therapeutics.

Last month, Coya reported that it has expanded its treatment research to see how GLP-1 drugs — a trending drug for weight loss — can enhance the effects of its proprietary therapeutics. By combining the medicines, Howard Berman, co-founder and CEO of Coya Therapeutics, says he thinks Coya can better treat these complex immune-based diseases. Read more.

Elad Inbar, founder and CEO of RobotLAB

Elad Inbar is the founder and CEO of RobotLAB. Photo courtesy of RobotLAB

Elad Inbar, founder and CEO of RobotLAB, who in July expanded his company’s Texas franchise operations with the opening of a Houston branch.

“For many years, robots were toys — for geeks. You had to build them yourself, program them yourself,” Inbar says.

But the electronics revolution that brought handheld phones to the mainstream inspired Inbar to turn that concept to robotics when he formed RobotLAB in 2007.

“To me, this was completely a wake up call — seeing the market shift, and you know, bringing the opportunity to the mass market,” he says. Read more.

Steve Altemus, co-founder, president, and CEO of Intuitive Machines

Per the contract, Intuitive Machines will provide near space communications and navigation services for NASA. Photo via intuitivemachines.com

Houston-based space exploration, infrastructure, and services company Intuitive Machines has snagged a deal with NASA that could be worth more than $4 billion.

Under the contract, Intuitive Machines (Nasdaq: LUNR, LUNRW) will supply communication and navigation services for missions in the “near space” region, which extends from the earth’s surface to beyond the moon.

The five-year deal includes an option to add five years to the contract. In total, the contract could be worth $4.82 billion. The initial round of NASA funding runs from October 2024 through September 2029.

“This contract marks an inflection point in Intuitive Machines’ leadership in space communications and navigation,” Steve Altemus, CEO of Intuitive Machines, says. Read more.

You might be seeing more robots in restaurants, thanks to Texas-based RobotLAB. Photo courtesy of RobotLAB

Texas robotics company expands in Houston with service-focused automation technology

order's up

Snazzy sombrero-wearing robots are gliding over to your table, carrying chips, salsa, and drinks, electronic eyes wide open on its interactive screen, ready to serve. The bot, provided by the new Houston franchise branch of RobotLAB Inc., debuted at Johnny Tamales Tex-Mex Cantina in Missouri City last week.

The restaurant's owner, Anil Patel, arranged for a one-month trial rental of the machine. But so far, he tells InnovationMap that he’s pleased with his “no-brainer” decision to add a small food delivery robot, which he says has huge marketing potential.

“I’m a sucker for technology. You look at it, and I think this is the future,” says Patel, who used to work in the health care industry.

That vision is shared by Elad Inbar, founder and CEO of Dallas-based RobotLAB, who in July expanded his company’s Texas franchise operations with the opening of a Houston branch.

“For many years, robots were toys — for geeks. You had to build them yourself, program them yourself,” Inbar says.

Elad Inbar is the founder and CEO of Dallas-based RobotLAB. Photo courtesy of RobotLAB

But the electronics revolution that brought handheld phones to the mainstream inspired Inbar to turn that concept to robotics when he formed RobotLAB in 2007.

“To me, this was completely a wake up call — seeing the market shift, and you know, bringing the opportunity to the mass market,” he says.

The company started by providing small robots to schools, and the company now works with two-thirds of the school districts in the country, Inbar says, touting that it is the "largest, most experienced" robotics company.

Keith Edwards, who owns RobotLAB’s Houston franchise with his brother Daniel, said his office aims to provide 50 robots in its first year of operation. While the use of robots has become more common globally, especially in Asian hotels and restaurants, for American business owners, robots are definitely not a standard decision, Edwards says.

The challenge lies in educating them about how robotics provides a solution for staffing shortages, Edwards says. With the touch of a button, the robot used in Patel’s restaurant can be programmed to sing happy birthday and deliver a dessert, or return dirty dishes back to the kitchen sink.

Through its franchisees, RobotLAB has already set up robots inside numerous restaurants, including eight food delivery models at four Houston locations of revolving sushi bar Kura Sushi.

Wings Over Frisco in the Dallas metro area and entertainment complex AREA 254 in Killeen also use RobotLAB food delivery robots. In August, the Tulsa International Airport introduced, on a trial basis, “Cloi,” another bot from RobotLAB, that guides visitors and has a selfie feature.

RobotLAB provides some 50 types of robots, Inbar says, ranging in function from cleaning, warehouse stacking, to food delivery, with plans and potential for more.

The company also has a presence in the senior living space, with a humanoid life-sized interactive robot named Pepper, that works with residents who suffer from dementia. While no Houston senior communities have yet come on board, Inbar says the company works with assisted living communities in Dallas, Wisconsin, New Jersey and Virginia.

One of RobotLAB's devices specializes in senior care facilities. Photo courtesy of RobotLAB

RobotLAB does not manufacture the robots, but provides the models, which can be purchased or leased. The company partners with manufacturers all over the world to provide the robots.

The cost to purchase a robot outright ranges widely, anywhere from $3,400 for an autonomous vacuum cleaner to $32,000 for a life-sized model, according to the website.

It provides one-on-one service for all aspects of implementation and any repair.

The proof of concept and related costs for the trial run for the Johnny Tamales robot was $2,990, Edwards says, which would apply toward a possible purchase of the $9,500 robot.

The daily labor cost, according to Inbar, for a food delivery robot amounts to about $15 to $17 a day, and for cleaning robots, about $27 a day.

The delivery robots run on a battery charge which lasts which lasts from nine to 13 hours, depending on the model. A cleaning robot does not last as long, but can clean 20,000 square feet on a single charge, Inbar says, and discharge dirty water, charge itself and return to work.

In the coming weeks, Inbar says he plans a demonstration with area firefighters at a training facility in Dallas, to show them bots that can clear debris, fight fires and help perform rescues.

The fastest-growing sector of his business now is the cleaning robot, as the service industry, in particular, struggles with labor challenges, Inbar says. The Houston office just sold its first cleaning robot, Edwards said.

“There is more demand for cleaning automation, simply because people don’t want to do the job anymore,” says Inbar. “We are hearing from everyone, in every market sector, from hotels, to assisted living facilities, to warehouses, you name it, supermarkets — even movie theaters. They can’t find people to clean. Putting that on autopilot, in a way, is the solution."

Edwards and Inbar say RobotLAB’s customized local service and connection provides the missing integration link for many business owners, who are intrigued by robots but may be way of what is involved with the equipment.

“We are basically the car dealership model of robotics,” Inbar says.

Christina Garavaglia, executive director of the Southeast Texas region of the Texas Restaurant Association, says the industry usually adapts cutting-edge technology early on, and robots are no exception.

“One of the primary reasons for this is that technology, hopefully, if it does what it’s intended, provides a lot of efficiency, and can help with some of the very tight margins that all of our restaurants work with,” she says.

Local restaurateurs have generally had positive reactions to robots, she says.

RobotLAB has food delivery robots rolling out in Houston. Photo courtesy of RobotLAB

Eric’s Restaurant at the Hilton University of Houston Hotel was the first Texas restaurant to introduce a robot two years ago, as part of its student training, Garavaglia says, adding that she expects more restaurateurs to come on board.

The industry has “barely scanned the surface” in leveraging the potential for robots to maximize efficiency and create a unique customer experience, she said.

Jim Lewis, president of AREA 254, a 45,000-square-foot entertainment complex in Killeen, purchased three robots from RobotLAB and began using them in January.

The robot keeps the food warm, in its enclosed shelves, and frees up the servers. One robot can carry up to four pizzas, and go from table to table in one trip, directed by a software system activated by the QR code order at the table. And, just as important for Lewis, the robots provide the “fun, cool factor.”

“People love it, and robots put smiles on people’s faces,” Lewis says. “My guess is that it will pick up a lot of steam, especially in the family entertainment space, where buildings are so big. The robot provides a very practical solution to moving food long distances.”

Inbar says his company does not want to replace human labor with his robots, rather enhance it and free up time for humans while filling a labor gap prompted by a shift that began in the wake of the COVID pandemic.

“This is where the challenge is. They need people to move boxes in warehouses, cook, and clean floors, so automation is the solution,” Inbar says.

Garavaglia says restaurant servers may even see their tips increase, as they can engage longer with customers as the robot handles other chores. The gap between the tip and the amount of work done to earn it would close, she explains.

Most high-end restaurants pride themselves on the customer experience, she said, and “that can only be provided by a human person.”

“Feeling a trust, sense of connection, that is really a human trait, a human characteristic. So long as that is the case, human servers and human employees will always be necessary,” she says.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”