James Reinstein joins the Houston Innovators Podcast to discuss what's next for growing medical device company, Saranas. Photo courtesy

When James Reinstein took the helm of Houston-based Saranas in March 2020, he was tasked with taking the medical device company through its series B funding round and into larger clinical trials. Navigating these tasks during a global pandemic wasn't part of the plan.

"There was just so much uncertainty," Reinstein says on this week's episode of the Houston Innovators Podcast. "All of the funds didn't know which end was up, what hospitals would be doing, what procedures were going to begin again."

Saranas received FDA approval and began its clinical trials for its Early Bird Bleed Monitoring System in 2019. The device is designed to detect and track bleeding complications related to endovascular procedures. These medical procedures treat problems, such as aneurysms, that affect blood vessels. Around 20 percent of patients suffer a bleeding complication during endovascular procedures.

Reinstein explains that the way health tech funding trended over the past 18 months greatly affected Saranas. The device fell outside the parameters of what investors were looking for during this pandemic time. However, Reinstein explains, the Early Bird worked and had FDA approval — that made all the difference.

"We are very confident that the product does work and it can have a significant impact for hospitals and patients," Reinstein says. "Eventually, the term sheets came in."

Saranas announced in July that it closed a $12.8 million series B investment led by Wisconsin-based Baird Capital, the venture capital and global private equity arm of Baird, a global company with a location in Houston. Austin-based S3 Ventures also supported the round.

The funds will propel Saranas into its next phase, which includes growing its team, larger trials, and a next-generation product.

Reinstein has had decades in health care innovation all over the world, with a large chunk of his career at Boston Scientific. He's seen Houston's innovation ecosystem evolve.

"I do think that there's a great potential for Houston to really develop the industry," Reinstein says. "There's just two areas that need to get fortified. One is the funding and getting the funds directed to Houston companies — with the idea that the company stays in Houston. ... The other side of the coin is really finding the talent to come in and run the companies, take on leadership positions."

Reinstein shares more details on what's next for Saranas, as well as his advice for med tech entrepreneurs and observations on Houston's innovation ecosystem on the show. Listen to the full interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.


The results are in for Houston-based Saranas' clinical trials. Courtesy of Saranas

Houston early bleeding detection device company reveals results of its clinical trials

blood tests

A Houston-based startup is closer to taking flight with a medical device designed to catch bleeding complications during medical procedures that involve blood vessels.

On May 22, researchers presented the results of a study showing the Early Bird Bleed Monitoring System from Houston-based Saranas Inc. detected various levels of bleeding in 63 percent of the patients who underwent endovascular procedures. These procedures treat problems, such as aortic aneurysms, that affect blood vessels.

No troubles were reported with the Early Bird device during the clinical trial, the researchers say.

Before this study, the Early Bird device hadn't been tested in humans. In all, 60 patients in five states participated in the clinical trial, which ran from August to December last year. Findings of the study were unveiled at the Society for Cardiovascular Angiography Interventions 2019 Scientific Sessions in Las Vegas.

The study's authors say they plan to continue evaluating the device at medical institutions that want to better manage bleeding during endovascular procedures.

"This is the first time we're seeing how this device could help in a real-world patient setting, and we were very encouraged by the results. Right now, patients have a risk of vessel injury when undergoing endovascular procedures where the femoral artery or vein is used for vascular access," Dr. Philippe Genereux, principal investigator for the study and a cardiologist at Morristown Medical Center in Morristown, New Jersey, says in a news release.

"This technology allows us to detect bleeding in real-time," Genereux adds, "which means we can take action quickly and improve the outcomes of the procedure and recovery for the patient."

In March, the Early Bird device — invented at Houston's Texas Heart Institute — received the U.S. Food and Drug Administration's approval as a "novel" medical device.

Saranas says Early Bird is the first and only device of its type. The FDA approval and the promising results of the clinical trial pave the way for the eventual launch of the device into the healthcare market.

A forecast from professional services firm KPMG predicts the global market for medical devices will reach nearly $800 billion by 2030. Early Bird aims to capture a sliver of that market by addressing an expensive and potentially fatal problem. One-fifth of patients experience bleeding complications during large-bore endovascular procedures. Research shows these complications are associated with a greater risk of death, longer hospital stays, and higher healthcare costs.

The Early Bird device is meant to decrease those complications by quickly alerting medical professionals to signs of bleeding during endovascular procedures.

As explained by the Texas Heart Institute, the Early Bird employs a sheath — a plastic tube that helps keep arteries and vessels open — embedded with sensors that measure the electrical resistance across a blood vessel. When the Early Bird senses a change in the electrical resistance, medical professionals receive audible and visual notifications about potential internal bleeding. If detected early, this bleeding can be minimized.

Altogether, Saranas has raised $12 million from investors, including a $2.8 million round in May 2018. The company was founded in 2013.

"What attracted me to Saranas is that our solution has the potential to meaningfully reduce serious bleeding complications that worsen clinical outcomes and drive up healthcare costs," says Zaffer Syed, who joined the startup as president and CEO in 2017. "In addition, our device may support access of important minimally invasive cardiac procedures by allowing them to be performed more safely."

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CultureMap Emails are Awesome

Following a pivot, this Houston founder is ready make her mark on the creator economy

houston innovators podcast episode 171

When Madison Long started her company with her co-founder and friend, Simone May, she knew she wanted to do one thing: Provide a platform for young people to have reliable access to payment for their skills and side hustles. Through starting a business, making a name change, launching a beta, going through a pivot, completing an accelerator, and more — that mission hasn't changed. And now, young people across the country can opt into the platform.

Houston-based creator economy platform Clutch celebrated its nationwide launch earlier this month. The platform connects brands to its network of creators for reliable and authentic work — everything from social media management, video creation, video editing, content creation, graphic design projects, and more.

When the company first launched its beta in Houston, the platform (then called Campus Concierge) rolled out at three Houston-area universities: Texas Southern University, Rice University, and Prairie View A&M. The marketplace connected any students with a side hustle to anyone on campus who needed their services.

Long shares on this week's Houston Innovators Podcast that since that initial pilot, they learned they could be doing more for users.

"We recognized a bigger gap in the market," Long says. "Instead of just working with college-age students and finding them side hustles with one another, we pivoted last January to be able to help these young people get part-time, freelance, or remote work in the creator economy for businesses and emerging brands that are looking for these young minds to help with their digital marketing presence."

Once focusing on the gig economy, Clutch changed its focus to the creator economy. The founders launched a new beta after closing $1.2 million in seed funding last year.

"Even though we did have to pivot, we're excited to be at the place now where we do deeply understand how to service both sides of our marketplace — the next-gen creatives and the emerging brands — so that they can really empower each other to meet their goals," Long says on the show.

Clutch, which went through the DivInc Houston accelerator, credits a part of the company's ability to survive the challenges from making pivots on being founded in Houston.

"We attribute a lot of Clutch's success — especially early on — to being located in Houston," Long says, explaining that she moved to Houston from California in 2021 to focus on the company. "It was physically being in the tech ecosystem that was blossoming in the Houston network that allowed us to feel safe making the pivots we were making and get a lot of guidance from mentors we were meeting."

She shares more about what's next for Clutch on the podcast. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

10 can't-miss Houston business and innovation events for February

where to be

It's time to look at what's on the agenda for February for Houston innovators — from pitch competitions to networking events.

Here's a roundup of events not to miss this month. Mark your calendars and register accordingly.

Note: This post might be updated to add more events.

Feb. 8 — Digital Marketing Luncheon

Join Insperity, a partner of The Cannon, and digital marketing expert, Danny Gavin, at The Cannon Downtown for a lunch and learn.

The event is Wednesday, February 8, at noon, at The Cannon Downtown. Click here to register.

Feb. 9 — Innovation on Tap: Fred Higgs, Engineering at Rice University

Discuss research in the speaker’s engineering lab at Rice University on key Industry 4.0 technologies, namely additive manufacturing.

The event is Thursday, February 9, at 4 pm, at the Ion. Click here to register.

February 10 — Women in Leadership Conference 

The 23rd annual Women in Leadership Conference will be held in-person at Rice University. The conference has been a beacon of inspiration in the Houston community, empowering women to accomplish their career goals. In panel discussions and interactive workshops, attendees hear from leaders across different industries, explore various approaches to leadership, and discuss future opportunities for success.

The event is Friday, February 10, at 8 am, at McNair Hall at Rice University. Click here to register.

Feb. 15 — Real Talk from Real VCs

Join this event for a candid fireside chat on venture capital and its role in supporting and growing innovative startups.

The event is Wednesday, February 15, at 5:30 pm, at the Ion. Click here to register.

Feb. 16 — Engage VC: Lerer Hippeau

Lerer Hippeau is an early-stage venture capital firm founded and operated in New York City. Since 2010, they have invested in entrepreneurs who embody audacity, endurance, and winning mindset – good people with great ideas who aren't afraid to do hard things. Join the HX Venture Fund to hear Caitlin Strandberg, Partner at Lerer Hippeau discuss her perspective on how to build and scale a great company, what early-stage investors are looking for, why Houston, and market trends among other topics.

The event is Thursday, February 16, at 8:30 am, at the Ion. Click here to register.

Feb. 16 — Female Founders and Funders

Calling all rockstar female founders and investors in the Houston area. Mark your calendars for this month's Female Founders and Funders meetup. Coffee and breakfast is provided and the event is free to attend.

The event is Thursday, February 16, at 9 am, at Sesh Coworking. Click here to register.

Feb. 21 — Web3 & HOU: Demystifying the Web3 Space Panel I

Join us to learn more about Web3 and its numerous applications.

The event is Tuesday, February 21, at 6 pm, at the Ion. Click here to register.

Feb. 22 — The Trailblazer’s Guide to Cultivating Authenticity

In this fun and interactive workshop presented by Erica D’Eramo of Two Peirs Consulting, we’ll look at how to foster a leadership style that works for you, even in the absence of role models.

The event is Wednesday, February 22, at 2 pm, at Sesh Coworking. Click here to register.

Feb. 22 — Houston Startup Showcase

The Houston Startup Showcase is a year-long series of monthly pitch competitions. Founders will pitch at the Ion and compete for the grand prize package. Watch the startups pitch their company and see who the judges will name the champion of the Houston Startup Showcase 2023.

The event is Wednesday, February 22, at 6 pm, at the Ion. Click here to register.

Feb. 23 — Navigating Innovation in the Corporate World

Join us for a fireside chat with leaders from Houston's largest employers, including Microsoft and Chevron to discuss how they have navigated successful careers in technology and innovation.

The event is Thursday, February 23, at 11:30 am, at the Ion. Click here to register.

Feb. 27-March 2 — Houston Tech Rodeo

The Houston Tech Rodeo is a conference showcasing the best and brightest of the Houston startup community in the region and beyond by putting investors, entrepreneurs, industry leaders, and creative minds in a room to talk about the biggest innovations and the future of tech sandwiched by some happy hours and friendly competition.

The events run Monday, February 27, through Thursday, March 2, at various locations in Houston. Click here to register.

Note: This post might be updated to add more events.


Houston innovator aims to connect the dots between data science and phenomena

eyes to the sky

As artificial intelligence continues to expand its sphere of influence, Spring-based expert Joe Schurman is looking to take this technology to an out-of-this-world space.

With his background includes working with advising defense and aerospace organizations like NASA, Schurman's latest venture PhenomAInon is perfectly aligned with what he’s been working towards since 2019. The company aims to be a multi-tiered subscription service and application that will be the world’s first cloud native data and AI platform for phenomenon-based data analysis that can analyze data from any source for space domain awareness and threat detection, according to Schurman.

The platform aims to provide end-to-end data and AI analysis, publish insights, build community, and provide cloud, data, and software consulting. PhenomAInon deploys data and AI services alongside modern data and AI engineering, per the website, to surface insights to explorers, researchers, organizations, publications, and communities through advanced data and AI analysis. Schurman has worked with the U.S. government's task force for unidentified anomalous phenomenon — any perceived aerial phenomenon that cannot be immediately identified or explained — known as UAPTF. The tool will run sensitive information and then get back custom video analysis. The public version of the tool will give the public the option to view videos and cases, and form their own analysis.

“We are working together with multiple teams both public and private to continue to curate the data sets, clear documents for public review, and provide advanced analytics and AI capabilities never seen before to the public,” Schurman tells InnovationMap. “From a data and analytics perspective, we are applying machine learning and advanced analytics to find correlations and anomalies in the incident reports across multiple data sets.

"Some of these are public, some are private, and some we are clearing for public review," he continues. "The analytics will go far beyond incident reporting and showcase heat maps, correlative incident maps to key private and public sector facilities, and trends analysis never reported — e.g. incident reporting correlated with time, weather, FAA, and drone flight data, etc. We also have a new content analysis platform where users will be able to eventually run their own AI and ML analysis on their own videos.”

Schurman was first able to show this to the world in 2019, when as an adviser for To The Stars Academy of Arts and Science, or TTSA. He also appeared on History Channel’s “Unidentified: Inside America's UFO Investigation” to show the Pentagon’s former Advanced Aerospace Threat Identification Program head and TTSA Director of Special Programs Luis Elizondo how the AI platform could be helpful in tracking data related to Unidentified Aerial Phenomena.

Now, PhenomAInon's app is a work-in-progress. While it soft launched in May of 2022, Schurman says they have several data sets that are awaiting clearing from the U.S. government, as well as the content analysis tool in development to launch possibly by the summer. Schurman also hopes they will curate the largest library of incident videos, images, and audio recordings.

The subject of UAP continues to attract new discussions from government officials and industry professions across aerospace, academia, and more. In Houston, Rice University's Woodson Research Center and its humanities department host one of the largest archives of UAP and paranormal data, notes, and research that include documents from CIA programs on remote viewing.

Schurman says he's looking to provide even more data and information in this space.

“This phenomenon, it’s implications to multiple aspects of our lives and possible security threats, all come down to a data problem and the organizations that have been in place to-date just have not had the level of cloud, data and AI engineering capabilities we take for granted and have access to in the private sector,” says Schurman. “My goal is to bring this all together, starting with PhenomAInon.”