gBETA has announced its second Houston cohort. Photo courtesy of gBETA

An early-stage startup accelerator with a national presence has announced its latest cohorts across the country. Five Houston companies have been named to the local class.

The accelerator, gBETA, is a part of Madison, Wisconsin-based gener8tor's suite of accelerators, and announced its plan to launch in Houston in September 2019. The program's inaugural cohort premiered in May and conducted the first program this summer completely virtually.

This week, gBETA named 50 startups across 10 cohorts to its fall program. Here are the five startups selected from Houston:

  • DOSS: Launched in April, DOSS uses artificial intelligence and data aggregation in the homebuying process.
  • Camelia Alise: The company creates gender-neutral skincare products to treat pseudo-folliculitis condition and has developed a specific spa curriculum for aspiring spa owners and specialists.
  • CaseCTRL: A management platform for surgeons, CaseCTRL's software-as-a-service technology uses AI and logistics to lower operational costs and simplify surgical planning.
  • Melanoid Exchange: An online platform, Melanoid Exchange is giving small minority businesses the opportunity to grow their business through eCommerce.
  • ScalaMed: The company has developed a smart prescriptions platform that provides care teams real-time information on their patients' drug management, and patients with an empowering tool that helps them take control over the prescription process.

The no-cost, equity-free program will last seven weeks and kicked off on October 1. While the program will continue to be virtual, gBETA's operations are located in Amegy Bank's Downtown Launchpad along with Impact Hub Houston and MassChallenge Texas.

"Over the past year, Central Houston has focused on establishing Downtown as a vibrant innovative center of gravity for technology and entrepreneurship in the northern node of the Houston Innovation Corridor," says Robert Pieroni, director of economic development at Central Houston, a gBETA Houston sponsor, in the news release.

"The result has been recruiting nationally-acclaimed accelerator programs, such as gener8tor, to our city and creating Downtown Launchpad, an inclusive village that offers a framework of resources for these programs and the startups and entrepreneurs involved as they seamlessly navigate through the stages of startup production. We're thrilled that gener8tor is one of Downtown Launchpad's resident partners and look forward to the impact created by the startups in the fall cohort."

gBETA Houston's Virtual Pitch Night will be held on Wednesday, Nov. 18, at 5 pm. For more information and to RSVP, click here.

gBETA kicked off its 2020 fall accelerator virtually. Photo courtesy of gBETA

gBETA has five Houston startups growing through its early-stage program virtually. Getty Images

Early-stage accelerator announces inaugural Houston cohort

now streaming

Even amid a pandemic, a Houston startup accelerator focused on local, early-stage companies has announced its new cohort and is operating its program virtually.

International accelerator gener8tor announced last fall that its early-stage program, gBETA, was coming to Houston following a $1.25 million grant approved by Houston's Downtown Redevelopment Authority. gBETA, which named its local leader and opened applications in January, now has revealed the five companies that will participate in the free, no-equity accelerator.

"This cohort was selected from among a highly competitive pool of applicants, and I'm so pleased with how they have adapted to the impacts of COVID-19 on the program and their businesses," says Eleonore Cluzel, director of gBETA Houston, in a news release.

The program kicked off April 30 and the five companies will graduate at a virtual pitch event June 18. While completely virtual this time around, the plan was to co-locate the program with MassChallenge Texas in Amegy Bank's Downtown Launchpad. The program is expecting to continue with its second cohort later this year.

"We are committed to establishing Downtown as a nexus for innovation and a leader in urban entrepreneurship and we applaud the talent of the first cohort, especially under these unprecedented circumstances," says Jonathan Brinsden, Central Houston's board chair, in a news release. "We look forward to them joining MassChallenge in the Downtown Launchpad at Amegy at Main this coming summer."

The spring 2020 gBETA cohort includes:

  • Best Bites Houston — a food tourism company that conducts exclusive food tours both in-person and virtually, exploring culture within cuisine.
  • Blown Assignments LLC — a web tool geared at improving communication between student athletes and their coaches.
  • GRIND — a sportstech company that merges sports and design to create products and services for athletic training.
  • Learn2Code.Live — a provider of computer science programming company that serves both students and teachers virtually.
  • Zent LLC — the creator of an innovative toothbrush called the Zent Flex that improves oral disease prevention and — no matter how hard a user brushes — physically limits brushing pressure to the optimal pressure.


The cohort meets virtually via Zoom web meetings. Photo courtesy of gBETA Houston

Global accelerator gener8tor's early-stage program, gBETA, plans to begin its first cohort out of the Downtown Launch Pad in April. Courtesy of Downtown Launch Pad

New-to-Houston accelerator names program director, opens applications

Starting strong

The second of two top accelerator programs that have taken a bet on Houston has announced its new program director and opened applications for its spring 2020 cohort.

Wisconsin-based gener8tor announced in September that its pre-accelerator program, gBETA, would be launching in Houston. The program follows MassChallenge, another top accelerator, premiering in Houston last year. Both accelerator programs launched in Houston thanks to a $1.25 million grant approved by the Downtown Redevelopment Authority.

Eléonore Cluzel will lead the gBETA Houston program as director, and will be the point person for the program in the region for the two annual cohorts. Previously, Cluzel worked for Business France mentoring French startups and small businesses. In her new position, she says she's excited to support founders across all industries and foster innovation.

"We're adding another resource for local founders to grow their startups and to raise money, and not have to move to Silicon Valley to do it," she says. "We will also serve as a connector, introducing founders to mentors and investors within the community and across gener8tor broader network."

Ele\u0301onore CluzelEléonore Cluzel will lead the Houston gBETA Houston program as director. Courtesy of gBETA Houston

Currently, Cluzel has regular office hours out of The Cannon's space in the Downtown Launch Pad in Amegy Tower. gBETA will co-locate with MassChallenge on a separate floor of the building, and that space is expected to be ready ahead of the start of the first cohort in April.

"It's like having a one-stop shop of resources for the whole community in a central location," Cluzel says. "Since The Cannon is going to be among several coworking spaces in the community, we'll reach all areas of Houston, including Sugar Land, The Woodlands and Stratford and other neighborhoods"

Interested early-stage startups can apply online for the program until April 10, and the cohort begins on April 30. Only five companies are selected for the cohort, insuring individualized support and programming from gBETA. The free program is designed to equip its participating startups with early customer traction and preparation for later stage accelerators.

"I'm looking for a diverse cohort, encompassing underserved communities such as women, veterans and minorities," Cluzel tells InnovationMap. "I'm seeking highly unique, highly scalable businesses based in Houston. In Houston, we have a lot of venture capital firms that write huge checks, but we don't have a lot of investors that help with early seed-stage funding. We're looking for very early stage startups whose company we can help grow and connect with our local and national network of investors."

gBETA aims to act as a funnel to other accelerator programs, Cluzel says.

"We're looking forward to working cooperatively with other resources in town, such as Plug and Play, MassChallenge, The Founder Institute, Capital Factory, The Cannon, and other incubators, accelerators and resources."

The Cannon Houston's third location is planned to open on December 9. Photo courtesy of The Cannon

Photos: The Cannon Houston's downtown space expects to open its doors early next month

ready for liftoff

A Houston entrepreneurial hub plans to open its third coworking space location only a few weeks after its main campus debuted in West Houston.

The Cannon Houston's newest location will be a 17,000-square-foot space on the top floor of The Cannon Tower at Amegy on Main in Downtown Houston. The opening date for the new space is Monday, December 9.

The announcement follows the grand opening of The Cannon's 120,000-square-foot flagship space, which is now close to being completely leased by startups and small businesses, and represents another step in the company's ambitious expansion plan.

"We've long known that we will need multiple locations across Houston in order to serve our mission of supporting Houston's entrepreneurs, and we are thrilled to work with an incredibly forward-thinking organization like Amegy to continue to fulfill this mission," says Cannon founder and president, Lawson Gow, in a news release. "The Cannon Tower at Amegy on Main will be unlike any other space in the city, in which we will be developing a 'vertical village' of innovation, programs, and resources, transforming Amegy on Main into a hub for Downtown Houston's entrepreneurs."

Gow — who is the son of David Gow, owner of InnovationMap's parent company, Gow Media — recently transitioned into his position as The Cannon named Jon Lambert as CEO earlier this month.

The Cannon's space is just one part of the equation that is the Downtown Launch Pad — a joint project between Central Houston, Downtown Redevelopment Authority, The Cannon, and Amegy Bank. The Amegy building will also house MassChallenge and gener8or, as well as event and common space for programming on the 11th floor.

"Amegy Bank is thrilled to be a part of the expansion of the innovation community by offering space, amenities, and business development support," says Kelly Foreman, Amegy Bank's senior vice president and manager of corporate real estate and facilities, in a news release. "We have a long track record of helping businesses grow, and creating this space for a hub of start-ups and accelerators is yet another way to do just that."

Moving forward, The Cannon will play a role in expanding workspace, resources, and programming in the building. The space is now open for leasing, and the first 100 members to join the new space will receive free parking for the course of their membership.

Plans for growth

Photo courtesy of The Cannon

The Cannon Houston will be a major player as the Downtown Launch Pad expands throughout the building.

At The Houston Innovation Summit's first panel of the week, representatives from The Cannon, Amergy Bank, and Central Houston discussed game-changing plans for the Downtown Launch Pad. Image courtesy of The Cannon

3 takeaways from The Houston Innovation Summit's first panel

ICYMI

The Houston Innovation Summit is in full swing, and the first panel of the week's events started strong. Representatives from The Cannon Houston, Amegy Bank, and MassChallenge took the stage at Amegy Bank's downtown office — soon to be converted into the Downtown Launch Pad — to discuss big picture topics within Houston Innovation.

Grace Rodriguez hosted the panel that covered diversity and inclusion efforts, the growth of The Cannon, and what you can expect from Launch Pad. Here's what you may have missed from the event.

The Downtown Launchpad will shake up the innovation ecosystem

Robert Pieroni, director of economic development for Central Houston and an advisory board member for MassChallenge, set the scene for Houston innovation a few year ago. Houston was overlooked for the Amazon headquarters, and it was the wakeup call Houston needed.

Now, the city, with the help of organizations like Central Houston, has attracted major top 10 accelerators in the world to town and plans to house them in the same space — the Downtown Launch Pad, which is a joint venture project between Central Houston, Downtown Redevelopment Authority, The Cannon, and Amegy Bank.

The Launch Pad will occupy a few floors in the Amegy building to start. There will be coworking and event space, as well as a floor dedicated to MassChallenge and gener8tor — the two new-to-Houston accelerators.

"We'll be the only place in the United States that has co-located two top 10 accelerators," Pieroni says.

The project also is working with an incubator yet to be announced to help bring into the fold undeserved startups and entrepreneurs in Houston, and there will also be a bootcamp targeted directly at the disadvantaged within the innovation ecosystem.

From Amegy's perspective, the bank is committed to growing the building to being something unique and effective for startups, says Andy Buchmann, vice president of corporate real estate and property management at Amegy Bank.

"We are hopeful that this is only the first two floors that we have figured out, and we hope there are other three or four that come behind it as it grows into a real hub for startups in the years to come," Buchmann says.

The Cannon's new CEO has global growth on the mind

Earlier this month, The Cannon Houston brought on Jon Lambert to serve as CEO as the company plans to grow and scale. Lambert, who joined the panel, says that the Downtown Launch Pad was well timed for The Cannon as it's looking to find the optimal areas of the city to grow.

"The distribution of the city is unlike any other in terms of the pockets of where people live and work," Lambert says, adding that The Cannon has an opportunity to reach these pockets.

Looking beyond Houston — and even Texas, the company is poised for growth by taking its model to cities — nationally and even globally — that are underserved when it comes to coworking and incubation space.

"You'd be astonished at some of the people reaching out to us," Lambert says on the panel. Some of this interest, Lambert adds, is setting up The Cannon as a global entry point for international companies looking to do business in Houston.

Inclusivity is the priority

With global initiatives and with Houston being the most diverse city in America, the city's innovation ecosystem has a great responsibility to provide inclusion, and each of the panelists maintains that their organizations have that as a top priority.

The Launch Pad is being developed with this in mind, and Pieroni says it's in the perfect place to do that. Amegy Bank has long been committed to small businesses and the building's location — across the street from METRO's Downtown Transit Center — makes it so that anyone in Houston can get to the hub.

Gener8tor and MassChallenge are also committed to providing programming at no cost, which will open doors to the entire community to get involved.

"As a part of our agreement with gener8tor, the will host free lunch and learns with the community monthly," Pieroni says. "We are working with MassChallenge to make them even more frequent."

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.

Elon Musk's SpaceX is about to make its debut on Wall Street

Money Moves

Elon Musk's rocket company SpaceX will make its debut on Wall Street Friday, June 12, and both institutional and retail investors are expected to gobble up the 555.6 million shares going up for sale at $135 apiece. Musk, already the world's richest man, could become its first trillionaire.

SpaceX is likely to become the biggest IPO ever, with proceeds of around $75 billion. SpaceX hopes to become the first company to send people to Mars. In fact, part of Musk’s future compensation depends on SpaceX eventually establishing a colony of at least 1 million people on the red planet.

Why SpaceX is going public now

In a video conference on Musk's social media platform X, he told JPMorgan CEO Jamie Dimon that people have suggested for the last 10 years that he take SpaceX public. He's doing it now because the company plans to put 100,000 next-generation Starlink satellites into orbit. Deploying AI data centers in space is a “massive new growth base and you need capital for that,” he said.

Going public provides access to the capital that SpaceX needs. But it also exposes it to more scrutiny from shareholders and more regulatory oversight. That includes filing quarterly financial reports, which critics say incentivizes short-term thinking over longer-term planning and creates unnecessary costs for a company. Securities regulators are currently soliciting public comment on a proposal to require public companies to file the financial reports only twice every year.

How the IPO impacts the company

Musk will hold the majority of a special class of shares, giving him control over decisions related to company strategy, finances and personnel. On the latter, because of his ownership of most of these Class B shares, the only person who can fire Musk as CEO is Musk.

The company credits Musk with being the “driving force” behind its growth, innovation and success. But what happens if Musk is no longer in the picture? SpaceX warns that the loss of Musk could disrupt its ability to execute its strategy as well as hurt its “reputation and relationships with customers, partners and other stakeholders.”

The company also warns that finding a replacement with the same skills and experience as Musk would be time-consuming, if not nearly impossible. As Wedbush Securities analyst Dan Ives wrote Wednesday, “At the end of the day Musk is SpaceX and SpaceX is Musk.”

What could make or break SpaceX

Currently in the test phase, the gigantic reusable Starship rocket is key to SpaceX realizing Musk's ambitions. Much of the commercial space business hinges on SpaceX developing Starship’s capability to be fully reusable and hearty enough for a quick turnaround between flights. If that doesn't happen, SpaceX warns that putting data centers and satellites in space will take longer and cost more money, meaning it risks customers bailing on the company.

Analysts say that by pioneering reusable rockets, SpaceX has established a clear lead on competitors such as Blue Origin, led by Amazon founder Jeff Bezos. The Starlink satellite business competes with, among others, AST SpaceMobile – which is relying on a SpaceX rocket to send its latest generation of satellites into orbit next week.

The prospectus filed last week says SpaceX’s biggest potential market is the sale of business-oriented artificial intelligence products designed to transform how people get work done. It’s an opportunity SpaceX predicts would be worth $22.7 trillion if it could somehow dominate rivals like Anthropic, OpenAI and Microsoft in a highly competitive industry. But the prospectus shows no clear path to profitability for the xAI business, which merged with SpaceX earlier this year.

Why Wall Street is paying attention

If the SpaceX IPO is as successful, the stock could quickly join the Nasdaq 100, a widely followed index that tracks the 100 largest non-financial companies in the composite. That's important because some popular funds, such as the $460 billion QQQ exchange-traded fund, mimic the index and will automatically buy whatever is listed in the index.

Nasdaq recently changed its rules to allow select companies to enter the Nasdaq 100 after just 15 trading days.

S&P Dow Jones Indices, on the other hand, is sticking to established and more traditional thresholds that will not allow SpaceX or other companies with gargantuan IPOs faster entry into its S&P 500 index. That means even high-profile companies will still need to wait for their stocks to trade a full 12 months before they can enter the index.

Companies want to be in the S&P 500 in particular because it's arguably the most important index on Wall Street, with trillions of dollars either mimicking it exactly or benchmarked against it. Vanguard's VOO fund that tracks the S&P 500 has roughly $950 billion invested in it, for example.