Early-stage startup accelerator names latest Houston cohort

ready cohort 2

gBETA has announced its second Houston cohort. Photo courtesy of gBETA

An early-stage startup accelerator with a national presence has announced its latest cohorts across the country. Five Houston companies have been named to the local class.

The accelerator, gBETA, is a part of Madison, Wisconsin-based gener8tor's suite of accelerators, and announced its plan to launch in Houston in September 2019. The program's inaugural cohort premiered in May and conducted the first program this summer completely virtually.

This week, gBETA named 50 startups across 10 cohorts to its fall program. Here are the five startups selected from Houston:

  • DOSS: Launched in April, DOSS uses artificial intelligence and data aggregation in the homebuying process.
  • Camelia Alise: The company creates gender-neutral skincare products to treat pseudo-folliculitis condition and has developed a specific spa curriculum for aspiring spa owners and specialists.
  • CaseCTRL: A management platform for surgeons, CaseCTRL's software-as-a-service technology uses AI and logistics to lower operational costs and simplify surgical planning.
  • Melanoid Exchange: An online platform, Melanoid Exchange is giving small minority businesses the opportunity to grow their business through eCommerce.
  • ScalaMed: The company has developed a smart prescriptions platform that provides care teams real-time information on their patients' drug management, and patients with an empowering tool that helps them take control over the prescription process.

The no-cost, equity-free program will last seven weeks and kicked off on October 1. While the program will continue to be virtual, gBETA's operations are located in Amegy Bank's Downtown Launchpad along with Impact Hub Houston and MassChallenge Texas.

"Over the past year, Central Houston has focused on establishing Downtown as a vibrant innovative center of gravity for technology and entrepreneurship in the northern node of the Houston Innovation Corridor," says Robert Pieroni, director of economic development at Central Houston, a gBETA Houston sponsor, in the news release.

"The result has been recruiting nationally-acclaimed accelerator programs, such as gener8tor, to our city and creating Downtown Launchpad, an inclusive village that offers a framework of resources for these programs and the startups and entrepreneurs involved as they seamlessly navigate through the stages of startup production. We're thrilled that gener8tor is one of Downtown Launchpad's resident partners and look forward to the impact created by the startups in the fall cohort."

gBETA Houston's Virtual Pitch Night will be held on Wednesday, Nov. 18, at 5 pm. For more information and to RSVP, click here.

gBETA kicked off its 2020 fall accelerator virtually. Photo courtesy of gBETA

gBETA has five Houston startups growing through its early-stage program virtually. Getty Images

Early-stage accelerator announces inaugural Houston cohort

now streaming

Even amid a pandemic, a Houston startup accelerator focused on local, early-stage companies has announced its new cohort and is operating its program virtually.

International accelerator gener8tor announced last fall that its early-stage program, gBETA, was coming to Houston following a $1.25 million grant approved by Houston's Downtown Redevelopment Authority. gBETA, which named its local leader and opened applications in January, now has revealed the five companies that will participate in the free, no-equity accelerator.

"This cohort was selected from among a highly competitive pool of applicants, and I'm so pleased with how they have adapted to the impacts of COVID-19 on the program and their businesses," says Eleonore Cluzel, director of gBETA Houston, in a news release.

The program kicked off April 30 and the five companies will graduate at a virtual pitch event June 18. While completely virtual this time around, the plan was to co-locate the program with MassChallenge Texas in Amegy Bank's Downtown Launchpad. The program is expecting to continue with its second cohort later this year.

"We are committed to establishing Downtown as a nexus for innovation and a leader in urban entrepreneurship and we applaud the talent of the first cohort, especially under these unprecedented circumstances," says Jonathan Brinsden, Central Houston's board chair, in a news release. "We look forward to them joining MassChallenge in the Downtown Launchpad at Amegy at Main this coming summer."

The spring 2020 gBETA cohort includes:

  • Best Bites Houston — a food tourism company that conducts exclusive food tours both in-person and virtually, exploring culture within cuisine.
  • Blown Assignments LLC — a web tool geared at improving communication between student athletes and their coaches.
  • GRIND — a sportstech company that merges sports and design to create products and services for athletic training.
  • Learn2Code.Live — a provider of computer science programming company that serves both students and teachers virtually.
  • Zent LLC — the creator of an innovative toothbrush called the Zent Flex that improves oral disease prevention and — no matter how hard a user brushes — physically limits brushing pressure to the optimal pressure.


The cohort meets virtually via Zoom web meetings. Photo courtesy of gBETA Houston

Global accelerator gener8tor's early-stage program, gBETA, plans to begin its first cohort out of the Downtown Launch Pad in April. Courtesy of Downtown Launch Pad

New-to-Houston accelerator names program director, opens applications

Starting strong

The second of two top accelerator programs that have taken a bet on Houston has announced its new program director and opened applications for its spring 2020 cohort.

Wisconsin-based gener8tor announced in September that its pre-accelerator program, gBETA, would be launching in Houston. The program follows MassChallenge, another top accelerator, premiering in Houston last year. Both accelerator programs launched in Houston thanks to a $1.25 million grant approved by the Downtown Redevelopment Authority.

Eléonore Cluzel will lead the gBETA Houston program as director, and will be the point person for the program in the region for the two annual cohorts. Previously, Cluzel worked for Business France mentoring French startups and small businesses. In her new position, she says she's excited to support founders across all industries and foster innovation.

"We're adding another resource for local founders to grow their startups and to raise money, and not have to move to Silicon Valley to do it," she says. "We will also serve as a connector, introducing founders to mentors and investors within the community and across gener8tor broader network."

Ele\u0301onore CluzelEléonore Cluzel will lead the Houston gBETA Houston program as director. Courtesy of gBETA Houston

Currently, Cluzel has regular office hours out of The Cannon's space in the Downtown Launch Pad in Amegy Tower. gBETA will co-locate with MassChallenge on a separate floor of the building, and that space is expected to be ready ahead of the start of the first cohort in April.

"It's like having a one-stop shop of resources for the whole community in a central location," Cluzel says. "Since The Cannon is going to be among several coworking spaces in the community, we'll reach all areas of Houston, including Sugar Land, The Woodlands and Stratford and other neighborhoods"

Interested early-stage startups can apply online for the program until April 10, and the cohort begins on April 30. Only five companies are selected for the cohort, insuring individualized support and programming from gBETA. The free program is designed to equip its participating startups with early customer traction and preparation for later stage accelerators.

"I'm looking for a diverse cohort, encompassing underserved communities such as women, veterans and minorities," Cluzel tells InnovationMap. "I'm seeking highly unique, highly scalable businesses based in Houston. In Houston, we have a lot of venture capital firms that write huge checks, but we don't have a lot of investors that help with early seed-stage funding. We're looking for very early stage startups whose company we can help grow and connect with our local and national network of investors."

gBETA aims to act as a funnel to other accelerator programs, Cluzel says.

"We're looking forward to working cooperatively with other resources in town, such as Plug and Play, MassChallenge, The Founder Institute, Capital Factory, The Cannon, and other incubators, accelerators and resources."

The Cannon Houston's third location is planned to open on December 9. Photo courtesy of The Cannon

Photos: The Cannon Houston's downtown space expects to open its doors early next month

ready for liftoff

A Houston entrepreneurial hub plans to open its third coworking space location only a few weeks after its main campus debuted in West Houston.

The Cannon Houston's newest location will be a 17,000-square-foot space on the top floor of The Cannon Tower at Amegy on Main in Downtown Houston. The opening date for the new space is Monday, December 9.

The announcement follows the grand opening of The Cannon's 120,000-square-foot flagship space, which is now close to being completely leased by startups and small businesses, and represents another step in the company's ambitious expansion plan.

"We've long known that we will need multiple locations across Houston in order to serve our mission of supporting Houston's entrepreneurs, and we are thrilled to work with an incredibly forward-thinking organization like Amegy to continue to fulfill this mission," says Cannon founder and president, Lawson Gow, in a news release. "The Cannon Tower at Amegy on Main will be unlike any other space in the city, in which we will be developing a 'vertical village' of innovation, programs, and resources, transforming Amegy on Main into a hub for Downtown Houston's entrepreneurs."

Gow — who is the son of David Gow, owner of InnovationMap's parent company, Gow Media — recently transitioned into his position as The Cannon named Jon Lambert as CEO earlier this month.

The Cannon's space is just one part of the equation that is the Downtown Launch Pad — a joint project between Central Houston, Downtown Redevelopment Authority, The Cannon, and Amegy Bank. The Amegy building will also house MassChallenge and gener8or, as well as event and common space for programming on the 11th floor.

"Amegy Bank is thrilled to be a part of the expansion of the innovation community by offering space, amenities, and business development support," says Kelly Foreman, Amegy Bank's senior vice president and manager of corporate real estate and facilities, in a news release. "We have a long track record of helping businesses grow, and creating this space for a hub of start-ups and accelerators is yet another way to do just that."

Moving forward, The Cannon will play a role in expanding workspace, resources, and programming in the building. The space is now open for leasing, and the first 100 members to join the new space will receive free parking for the course of their membership.

Plans for growth

  

Photo courtesy of The Cannon

The Cannon Houston will be a major player as the Downtown Launch Pad expands throughout the building.

At The Houston Innovation Summit's first panel of the week, representatives from The Cannon, Amergy Bank, and Central Houston discussed game-changing plans for the Downtown Launch Pad. Image courtesy of The Cannon

3 takeaways from The Houston Innovation Summit's first panel

ICYMI

The Houston Innovation Summit is in full swing, and the first panel of the week's events started strong. Representatives from The Cannon Houston, Amegy Bank, and MassChallenge took the stage at Amegy Bank's downtown office — soon to be converted into the Downtown Launch Pad — to discuss big picture topics within Houston Innovation.

Grace Rodriguez hosted the panel that covered diversity and inclusion efforts, the growth of The Cannon, and what you can expect from Launch Pad. Here's what you may have missed from the event.

The Downtown Launchpad will shake up the innovation ecosystem

Robert Pieroni, director of economic development for Central Houston and an advisory board member for MassChallenge, set the scene for Houston innovation a few year ago. Houston was overlooked for the Amazon headquarters, and it was the wakeup call Houston needed.

Now, the city, with the help of organizations like Central Houston, has attracted major top 10 accelerators in the world to town and plans to house them in the same space — the Downtown Launch Pad, which is a joint venture project between Central Houston, Downtown Redevelopment Authority, The Cannon, and Amegy Bank.

The Launch Pad will occupy a few floors in the Amegy building to start. There will be coworking and event space, as well as a floor dedicated to MassChallenge and gener8tor — the two new-to-Houston accelerators.

"We'll be the only place in the United States that has co-located two top 10 accelerators," Pieroni says.

The project also is working with an incubator yet to be announced to help bring into the fold undeserved startups and entrepreneurs in Houston, and there will also be a bootcamp targeted directly at the disadvantaged within the innovation ecosystem.

From Amegy's perspective, the bank is committed to growing the building to being something unique and effective for startups, says Andy Buchmann, vice president of corporate real estate and property management at Amegy Bank.

"We are hopeful that this is only the first two floors that we have figured out, and we hope there are other three or four that come behind it as it grows into a real hub for startups in the years to come," Buchmann says.

The Cannon's new CEO has global growth on the mind

Earlier this month, The Cannon Houston brought on Jon Lambert to serve as CEO as the company plans to grow and scale. Lambert, who joined the panel, says that the Downtown Launch Pad was well timed for The Cannon as it's looking to find the optimal areas of the city to grow.

"The distribution of the city is unlike any other in terms of the pockets of where people live and work," Lambert says, adding that The Cannon has an opportunity to reach these pockets.

Looking beyond Houston — and even Texas, the company is poised for growth by taking its model to cities — nationally and even globally — that are underserved when it comes to coworking and incubation space.

"You'd be astonished at some of the people reaching out to us," Lambert says on the panel. Some of this interest, Lambert adds, is setting up The Cannon as a global entry point for international companies looking to do business in Houston.

Inclusivity is the priority

With global initiatives and with Houston being the most diverse city in America, the city's innovation ecosystem has a great responsibility to provide inclusion, and each of the panelists maintains that their organizations have that as a top priority.

The Launch Pad is being developed with this in mind, and Pieroni says it's in the perfect place to do that. Amegy Bank has long been committed to small businesses and the building's location — across the street from METRO's Downtown Transit Center — makes it so that anyone in Houston can get to the hub.

Gener8tor and MassChallenge are also committed to providing programming at no cost, which will open doors to the entire community to get involved.

"As a part of our agreement with gener8tor, the will host free lunch and learns with the community monthly," Pieroni says. "We are working with MassChallenge to make them even more frequent."

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Rice team keeps CO2-to-fuel devices running 50 times longer in new study

Bubbling Up

In a new study published in the journal Science, a team of Rice University researchers shared findings on how acid bubbles can improve the stability of electrochemical devices that convert carbon dioxide into useful fuels and chemicals.

The team led by Rice associate professor Hoatian Wang addressed an issue in the performance and stability of CO2 reduction systems. The gas flow channels in the systems often clog due to salt buildup, reducing efficiency and causing the devices to fail prematurely after about 80 hours of operation.

“Salt precipitation blocks CO2 transport and floods the gas diffusion electrode, which leads to performance failure,” Wang said in a news release. “This typically happens within a few hundred hours, which is far from commercial viability.”

By using an acid-humidified CO2 technique, the team was able to extend the operational life of a CO2 reduction system more than 50-fold, demonstrating more than 4,500 hours of stable operation in a scaled-up reactor.

The Rice team made a simple swap with a significant impact. Instead of using water to humidify the CO2 gas input into the reactor, the team bubbled the gas through an acid solution such as hydrochloric, formic or acetic acid. This process made more soluble salt formations that did not crystallize or block the channels.

The process has major implications for an emerging green technology known as electrochemical CO2 reduction, or CO2RR, that transforms climate-warming CO2 into products like carbon monoxide, ethylene, or alcohols. The products can be further refined into fuels or feedstocks.

“Using the traditional method of water-humidified CO2 could lead to salt formation in the cathode gas flow channels,” Shaoyun Hao, postdoctoral research associate in chemical and biomolecular engineering at Rice and co-first author, explained in the news release. “We hypothesized — and confirmed — that acid vapor could dissolve the salt and convert the low solubility KHCO3 into salt with higher solubility, thus shifting the solubility balance just enough to avoid clogging without affecting catalyst performance.”

The Rice team believes the work can lead to more scalable CO2 electrolyzers, which is vital if the technology is to be deployed at industrial scales as part of carbon capture and utilization strategies. Since the approach itself is relatively simple, it could lead to a more cost-effective and efficient solution. It also worked well with multiple catalyst types, including zinc oxide, copper oxide and bismuth oxide, which are allo used to target different CO2RR products.

“Our method addresses a long-standing obstacle with a low-cost, easily implementable solution,” Ahmad Elgazzar, co-first author and graduate student in chemical and biomolecular engineering at Rice, added in the release. “It’s a step toward making carbon utilization technologies more commercially viable and more sustainable.”

A team led by Wang and in collaboration with researchers from the University of Houston also recently shared findings on salt precipitation buildup and CO2RR in a recent edition of the journal Nature Energy.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

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