From enlightening talks to anniversary celebrations, here's where you need to be in January. Getty Images

Houston's innovation community is starting 2019 strong with plenty of business professional events.

If you know of innovation-focused events for February, email me at natalie@innovationmap.com with the details.

1. How to Start a Startup with Roberto Moctezuma, founder & CEO of Fractal River

Thinking 2019 is the year you finally turn your business idea into a startup? Station Houston wants to help. It's free to attend this discussion lead by Roberto Moctezuma, the founder and CEO of Houston-based Fractal River, an advisory firm. The talk will focus on identifying problems, determining market needs, learning important metrics, and more.

The event is from 6 to 7 pm on Tuesday, January 8, at Station Houston (1301 Fannin St., Suite 2440).

Learn more here.

2. January U.S. Oil & Gas Blockchain Forum Luncheon

For the first event of the year, the U.S. Oil & Gas Blockchain Forum is focusing on how blockchain can help the energy industry. Guest speakers are Andrew Bruce, CEO and founder of Houston-based Data Gumbo, and Rebecca Hofmann, blockchain strategist at Equinor.

The luncheon is from 11:30 am to 1:30 pm on Tuesday, January 15, at the Equinor Auditorium (2107 CityWest Blvd). Tickets to attend are $50.

Learn more here.

3. Salesforce Essentials Workshop: Houston

Attention small business owners: Salesforce has a workshop designed for you. Learn about the platform and how it can help your business strategy over lunch.

The workshop isn Tuesday, January 15, from noon to 2 p.m. at The Cannon (1336 Brittmoore Road) and is free to attend.

Learn more here.

4. Society of Petroleum Engineers Women-in-Energy Congress

Energy industry ladies take center stage of a full-day event focused on women in oil and gas. Susan Dio, chairman and president of BP America, will deliver the keynote address before the rest of the day's panels and presentations begin.

This event is January 18, from 8 a.m. to 3:30 p.m., at the Houston Community College West Houston Institute (2811 Hayes Road).

Learn more here.

5. Houston Startup Demo Day

Three Houston startups will present their product and business plan at The Station's monthly demo day. The companies and judges are still being determined, but the event details are finalized.

Hear the pitches on Wednesday, January 23, from 6 to 8 p.m., at Station Houston (1301 Fannin Street, Suite 2440). The event is free to attend.

Learn more here.

6. NRLC Workshop: Pitching Part 2: The Physical Pitch with Beth O'Sullivan

If you thought you were pitch perfect, think again. Beth O'Sullivan, a management senior lecturer at Rice University's Jones Graduate School of Business, is giving a free lecture on the art of pitching your company. The Liu Idea Lab for Innovation and Entrepreneurship is offering the event.

The lecture will be from 4 to 5:30 pm on Wednesday, January 23, at the Liu Idea Lab for Innovation and Entrepreneurship (6100 Main Street Cambridge Office Building, Suite 130).

Learn more here.

7. Women Entrepreneurs Pitch Party at The Cannon

Calling all angel investors — The Cannon Ventures would like to introduce you to a few female entrepreneurs this month. InnovationMap is a media partner for the event, and the goal is to generate connections between the entrepreneurs and potential investors.

The event takes place on Thursday, January 24, from 6:30 to 9 p.m. at The Cannon (1336 Brittmoore Road).

If you're an interested investor and would like to attend, email Jake Askew at jaskew@cannonventureshouston.com.

8. Oil & Gas Happy Hour Hosted by OGGN + The Cannon

Grab a beer and some bites at Oil & Gas Global Network's monthly happy hour — this time in collaboration with Houston-based The Cannon.

Join oil and gas professionals at The Cannon (1336 Brittmoore Road) on Tuesday, January 29, from 6 to 9 p.m. Tickets are $10 for this happy hour event, and proceeds go to Redeemed Ministries, a local charity to help human trafficking victims.

Learn more here.

9. Station Houston 3.0 and Launch Party

As Station Houston officially becomes a nonprofit on January 1, and, in preparation for its move to the Midtown Innovation District, the organization is revealing Station Houston 3.0 to start 2019 with. The free event is Wednesday, January 30, from 6 to 8 pm at Station Houston (1301 Fannin St., Suite 2440).

Guests can mingle until the short program and announcement, which is followed by light bites. Station will also be showing off Houston's first VR Lab and its new space.

Learn more here.

10. Inaugural meeting of the Houston Industrial Digital Transformation & IoT Meetup

Calling all digital and tech innovation leaders in oil and gas or utilities — there's a new group for you to join. The Houston Industrial Digital Transformation and IoT Meetup formed to bring leaders of industrial innovation together for collaboration and so that they can learn from each other's digital transformations.

The inaugural meetup is from 6 to 8 pm on Wednesday, January 30, at ChaiOne HQ (9 Greenway Plaza, Suite 850). It's free to attend.

Learn more here.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.