Historic Texas Southern University will host the September 12 Democratic debate, and Houston is expected to be the real economic winner. Courtesy photo

If past presidential debates are an accurate barometer, Houston stands to reap millions of dollars worth of benefits from what's been called the "Super Bowl of politics." However, one economist isn't casting his vote for any sizeable economic surge from the upcoming presidential debate in Houston.

On September 12, Houston's Texas Southern University, one of the largest historically black universities in the country, will host the third debate of the Democratic presidential primary season. The Democratic National Committee and ABC picked the 150-acre TSU campus for this showdown, where 10 Democratic candidates are set to take the stage at the 8,100-seat H&PE Arena.

While the Greater Houston Partnership isn't able to provide an estimated economic impact of the Houston debate, it still sees the value of Houston basking in the national spotlight.

"Texas Southern University hosting the third Democratic presidential primary debate here in Houston will focus national attention on the city for several days in much the same way the Republican presidential debate did back in 2016," Bob Harvey, president and CEO of the Greater Houston Partnership, tells InnovationMap. "These events put Houston top of mind among people across the country — including the companies and talented individuals we're working to recruit to Houston."

The debate will help showcase Houston as a diverse city that's tackling presidential-level issues like education, infrastructure, and climate change, Harvey says. Climate change, in particular, hits close to home in Houston, as the city is "redefining its role" as the Energy Capital of the World through local initiatives taking on renewables, carbon emissions, and sustainability, according to Harvey.

Three years ago, the University of Houston hosted a Republican presidential debate featuring five candidates. For historical context, Houston hosted the Democratic National Convention in 1928 and the Republican National Convention in 1992.

Brandon Rottinghaus, a professor of political science at UH who's an expert on the presidency, says nationally televised debates serve as a "massive platform" for host colleges and universities to recruit faculty and students beyond their normal regional or local confines. Furthermore, he says, presidential debates can elevate the status of these schools in the realm of "public discourse."

"These debates are also a way to connect to alumni networks flung far across the nation," Rottinghaus tells InnovationMap, "and give them some something to brag about that isn't sports-related."

No estimates were provided of the economic impact for the University of Houston debate, but other spots in the U.S. — communities and college campuses — that have hosted presidential debates tout millions of dollars in value from debate-related spending and free publicity.

In October 2012, the Boca Raton, Florida, area realized an immediate economic impact of $13.1 million from hosting the final debate ahead of that year's presidential election, as well as $63.7 million in free publicity from news coverage of the nationally televised event. Those figures come from a study commissioned by Lynn University, which hosted the debate. An accompanying survey found that after watching the debate, 4.7 million American adults definitely wanted to visit the Boca Raton area over the next five years.

Also in October 2012, the University of Denver hosted a general-election debate that generated an estimated $56 million in free publicity.

Victor Matheson, an economist at the College of the Holy Cross in Worcester, Massachusetts, dismisses those figures as inflated and irrelevant. And he says Houston shouldn't expect the city or TSU to receive any direct economic benefits from the September 12 debate.

For one thing, Matheson downplays the value assigned to free publicity surrounding a presidential debate. He complains that the methodology applied to tallying the benefits of so-called "earned media" coverage is flawed.

For another thing, Matheson notes that few people from outside the Houston area will be attending the debate at TSU, meaning little in the way of revenue from hotel stays, meals, and other visitor expenditures. "This isn't a Super Bowl," he says.

As a matter of fact, Houston hosted the 50th Super Bowl in February 2017 and fielded an economic impact of $347 million thanks to spending by 150,000 visitors, according to a study commissioned by the Houston Super Bowl Host Committee.

While not on the scale of a Super Bowl, the upcoming debate will attract positive attention for TSU, Matheson points out.

"This sort of debate can really put a college on the map, especially one like Texas Southern, a fairly obscure university from a national standpoint," he tells InnovationMap.

Matheson cites Saint Anselm College in Manchester, New Hampshire, as an example. Few people outside New England would have heard of Saint Anselm without its frequent hosting of presidential debates since the 1980s, he says.

The college has been dubbed the "academic epicenter" of the first-in-the-nation New Hampshire primary. During the 2015-16 political season alone, Saint Anselm hosted one Republican and one Democratic presidential debate, leading to more than 8,100 mentions in the news media of the college or its New Hampshire Institute of Politics.

"So, the effect for colleges is real, but there is still a question about how big it is," Matheson says. "And let's not pretend that the debate is somehow going to put Houston on the map. If Houston isn't already on your map, you really need to get yourself a new map."

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.