3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Erica Sinner of DanceKard, Angela Wilkins of Rice University, and Gina Luna of GP Capital Partners. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from dating tech to investment — recently making headlines in Houston innovation.

Erica Sinner, founder of DanceKard

Houston-based DanceKard is focused on getting singles off the endless swiping in order to make lasting connections and relationships. Photo courtesy of DanceKard

A proud Houstonian, Erica Sinner, whose background is in commercial real estate, was interested in creating a dating app that brought in local businesses. She launched DanceKard with several different offerings — all geared at driving in-person connections. Users can join the app to find events — not necessarily singles-specific events, although those are an option, but meetups where you know a certain number of singles will be in attendance.

"We focus a lot on group dating," Sinner explains. "That's something nobody does."

Singles, along with their single friends, can indicate on the app that they are interested in four, six, or eight-person dates, and see if their are other groups of friends looking to connect. Click here to read more.

Angela Wilkins, executive director of the Ken Kennedy Institute at Rice University

"Better and personalized healthcare through AI is still a hugely challenging problem that will take an army of scientists and engineers." Photo courtesy

Angela Wilkins, executive director of the Ken Kennedy Institute at Rice University, knows data and artificial intelligence can hold bias. It is, after all, designed by humans who have biases whether they know it or not. An issue with this is when these biases affect health care.

"AI presents the opportunity to bring greater personalization to healthcare, but it equally presents the risk of entrenching existing inequalities. We have the opportunity in front of us to take a considered approach to data collection, regulation, and use that will provide a fuller and fairer picture and enable the next steps for AI in healthcare," Wilkins writes in her guest column. Click here to read more.

Gina Luna, partner at GP Capital Partners

Gina Luna joins the Houston Innovators Podcast this week. Photo courtesy of Gina Luna

For most of Gina Luna's career, which includes two decades at JP Morgan before running her own strategic consulting firm, her bread and butter has been working with privately held, lower-middle market companies. Her latest endeavor is no different.

Luna — along with Paul Hobby, and Peter Shaper at Genesis Park — have joined forces to create GP Capital Partners, a new $275 million fund structured as a Small Business Investment Company. The fund will deploy funding into 20 to 25 companies within the region.

"The four of us just thought there was a real opportunity to bring this kind of capital to middle market companies in Houston, Texas, an the Gulf Coast region," Luna says on this week's episode of the Houston Innovators Podcast. "We have already seen, even in the relatively early days, there is a need an an opportunity to invest in great companies, and we are really excited to be doing that." Click here to read more and stream the podcast.

Houston-based DanceKard is focused on getting singles off the endless swiping in order to make lasting connections and relationships. Photo courtesy of DanceKard

Houston entrepreneur is flipping the switch on online dating with new app

so over swiping

Like most people who are single and looking for a relationship, Erica Sinner is familiar with the dating apps. She's swiped and messaged with men in her area, but has little to show for it other than comically lazy responses from not-so potential soulmates.

Then Sinner had an idea. What if there was a platform that encouraged meetups and group dates and limited in-app conversations? An anti-dating app platform that took users off their phones, paused endless swiping, and also gave local businesses — bars, restaurants, etc. — a chance to host events or generate new business?

Then she thought, why not create it herself? Sinner started DanceKard to fill this need within the dating app landscape. After a soft launch a couple months ago, the app has over 170 users on the platform and recently joined gBETA's early-stage accelerator program.

"I think people forgot how great an in-person meeting is whenever you're getting to know someone," Sinner tells InnovationMap. "I love the fact that dating apps have made it easier to meet people, but at the end of the day, after you spend three days or a week talking to someone and then you meet them in person, and there's just something you don't like."

Sinner explains it like reading the book before seeing the movie — everyone is going to seem better when you build them up in your head.

"I've found, personally, there are guys who I met in person who are amazing, and I just wouldn't have thought that if I saw them online first," she says.

The name is a callback to when women connected with their suitors at a local dance. Women penciled in dances with their gentlemen callers, and that's how they got to know them — through a spin around the dancefloor.

"We're the modern day version of that type of dating," Sinner says, with less dancing but right in line with generating in-person conenctions.

A proud Houstonian, Sinner, whose background is in commercial real estate, was interested in bringing in local businesses from the start. DanceKard has several different offerings — all geared at driving in-person connections. Users can join the app to find events — not necessarily singles-specific events, although those are an option, but meetups where you know a certain number of singles will be in attendance.

"We focus a lot on group dating," Sinner explains. "That's something nobody does."

Singles, along with their single friends, can indicate on the app that they are interested in four, six, or eight-person dates, and see if their are other groups of friends looking to connect.

DanceKard also provides discounts and deals at its business partners' establishments. This drives business while also making deciding where to meet up a lot easier — and affordable.

"Everyone knows dating can get expensive — especially for the guys," Sinner says. "So, daters can go out on these dates and use a discount."

At the end of the day, DanceKard and Sinner are laser focused on creating relationships for their users. Modern dating has been defined by swiping on apps or drinking in bars, but that doesn't have to be your only options. DanceKard's events and opportunities will be more than just at bars — users can meet at the museum or the zoo and have an activity to connect with others over.

"People are looking for things other than drinking," she says. "They're realizing that if they are going to a bar where there are singles, that doesn't equate to a relationship."

For now, she's also focused on her hometown of Houston and is really being intentional about supporting local businesses and Houstonians themselves.

"Houston is a great opportunity," she says. "It's not about me, it's about this town. We have great people and great businesses."

Here's what companies are in the latest cohort for gBETA. Photo courtesy of gBETA

Early-stage accelerator announces 5 startups to its fall 2021 Houston cohort

ready to grow

An early-stage accelerator has picked its latest cohort of five Houston companies.

The Fall 2020 cohort of gBETA Houston includes:

  • AllIDoIsCook is founded by Tobi Smith and focused on exposing the world to Africa's cuisine by manufacturing gourmet food products delivered directly to customer doors and available at grocers. Since launching, AllIDoIsCook has built out a manufacturing facility, shipped over 8,000 boxes and generated $1.1 million in revenue all without outside funding.
  • Chasing Watts makes it easy for cyclists to coordinate or find rides with fellow riders in their area with its web-based and native application. The company has over 3,000 users and grew 135 percent from Q2 to Q3 in new ride views.
  • DanceKard, founded by Erica Sinner, is a new dating platform that connects individuals and groups with one another by bringing the date to the forefront of the conversation and making scheduling faster and easier with special promotions featuring local establishments. Since launching in August of 2021, DanceKard has over 170 users on the platform.
  • Dollarito is a digital lending platform that helps the low-income Hispanic population with no credit history or low FICO score access fair credit. Founded by Carmen Roman, Dollarito applies AI into banking, transactional and behavioral data to evaluate the repayment capability more accurately than using FICO scores. The company has1,000 users on their waitlist and plans to beta test with 100 or more customers in early 2022.
  • SeekerPitch, founded by Samantha Hepler, operates with the idea that jobseekers' past job titles and resumes are not always indicative of their true capabilities. Launched last month, SeekerPitch empowers companies to see who jobseekers are as people, and get to know them through comprehensive profiles and virtual speed interviews, and the company already has 215 jobseekers and 20 companies on the platform, with one pilot at University of Houston and three more in the pipeline.

The companies kicked off their cohort in person on October 18, and the program concludes on December 14 with the gBETA Houston Fall 2021 Pitch Night. At this event, each company will present their five-minute pitch to an audience of mentors, investors, and community members.

"The five founding teams selected for our gBETA Houston Fall 2021 cohort are tackling unique problems they have each experienced personally, from finding access to cultural foods, fitness communities and authentic dating experiences to challenges with non-inclusive financing and hiring practices," says Kate Evinger, director of gBETA Houston, in the release. "The grit and passion these individuals bring to their roles as founders will undoubtedly have a tremendous impact in the Houston community and beyond."

The accelerator has supported 15 Houston startups since it launched in Houston in early 2020. The program, which is free and hosted out of the Downtown Launchpad, is under the umbrella of Madison, Wisconsin-based international accelerator, gener8tor.

"Downtown Launchpad is an innovation hub like no other, and I am so proud of what it is already and what it will become," says Robert Pieroni, director of economic development at Central Houston Inc., in the release. "The five startups selected for the gBETA Houston Fall 2021 cohort are exploring new challenges that can become high-impact Houston businesses."

gBETA announced its plan to launch in Houston in September 2019. The program's inaugural cohort premiered in May and conducted the first program this summer completely virtually. The second cohort took place last fall, and the third ran earlier this year.

"These founders are building their companies and benefiting from the resources Downtown Launchpad provides," Pieroni continues, "and the proof is in the data – companies in these programs are creating jobs, growing their revenues and exponentially increasing their funding, which means these small starts up of today, working in Downtown Launchpad, are growing into the successful companies of tomorrow."

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

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