3 Houston innovators to know this week

who's who

This week's roundup of Houston innovators includes Erica Sinner of DanceKard, Angela Wilkins of Rice University, and Gina Luna of GP Capital Partners. Courtesy photos

Editor's note: In this week's roundup of Houston innovators to know, I'm introducing you to three local innovators across industries — from dating tech to investment — recently making headlines in Houston innovation.

Erica Sinner, founder of DanceKard

Houston-based DanceKard is focused on getting singles off the endless swiping in order to make lasting connections and relationships. Photo courtesy of DanceKard

A proud Houstonian, Erica Sinner, whose background is in commercial real estate, was interested in creating a dating app that brought in local businesses. She launched DanceKard with several different offerings — all geared at driving in-person connections. Users can join the app to find events — not necessarily singles-specific events, although those are an option, but meetups where you know a certain number of singles will be in attendance.

"We focus a lot on group dating," Sinner explains. "That's something nobody does."

Singles, along with their single friends, can indicate on the app that they are interested in four, six, or eight-person dates, and see if their are other groups of friends looking to connect. Click here to read more.

Angela Wilkins, executive director of the Ken Kennedy Institute at Rice University

"Better and personalized healthcare through AI is still a hugely challenging problem that will take an army of scientists and engineers." Photo courtesy

Angela Wilkins, executive director of the Ken Kennedy Institute at Rice University, knows data and artificial intelligence can hold bias. It is, after all, designed by humans who have biases whether they know it or not. An issue with this is when these biases affect health care.

"AI presents the opportunity to bring greater personalization to healthcare, but it equally presents the risk of entrenching existing inequalities. We have the opportunity in front of us to take a considered approach to data collection, regulation, and use that will provide a fuller and fairer picture and enable the next steps for AI in healthcare," Wilkins writes in her guest column. Click here to read more.

Gina Luna, partner at GP Capital Partners

Gina Luna joins the Houston Innovators Podcast this week. Photo courtesy of Gina Luna

For most of Gina Luna's career, which includes two decades at JP Morgan before running her own strategic consulting firm, her bread and butter has been working with privately held, lower-middle market companies. Her latest endeavor is no different.

Luna — along with Paul Hobby, and Peter Shaper at Genesis Park — have joined forces to create GP Capital Partners, a new $275 million fund structured as a Small Business Investment Company. The fund will deploy funding into 20 to 25 companies within the region.

"The four of us just thought there was a real opportunity to bring this kind of capital to middle market companies in Houston, Texas, an the Gulf Coast region," Luna says on this week's episode of the Houston Innovators Podcast. "We have already seen, even in the relatively early days, there is a need an an opportunity to invest in great companies, and we are really excited to be doing that." Click here to read more and stream the podcast.

Houston-based DanceKard is focused on getting singles off the endless swiping in order to make lasting connections and relationships. Photo courtesy of DanceKard

Houston entrepreneur is flipping the switch on online dating with new app

so over swiping

Like most people who are single and looking for a relationship, Erica Sinner is familiar with the dating apps. She's swiped and messaged with men in her area, but has little to show for it other than comically lazy responses from not-so potential soulmates.

Then Sinner had an idea. What if there was a platform that encouraged meetups and group dates and limited in-app conversations? An anti-dating app platform that took users off their phones, paused endless swiping, and also gave local businesses — bars, restaurants, etc. — a chance to host events or generate new business?

Then she thought, why not create it herself? Sinner started DanceKard to fill this need within the dating app landscape. After a soft launch a couple months ago, the app has over 170 users on the platform and recently joined gBETA's early-stage accelerator program.

"I think people forgot how great an in-person meeting is whenever you're getting to know someone," Sinner tells InnovationMap. "I love the fact that dating apps have made it easier to meet people, but at the end of the day, after you spend three days or a week talking to someone and then you meet them in person, and there's just something you don't like."

Sinner explains it like reading the book before seeing the movie — everyone is going to seem better when you build them up in your head.

"I've found, personally, there are guys who I met in person who are amazing, and I just wouldn't have thought that if I saw them online first," she says.

The name is a callback to when women connected with their suitors at a local dance. Women penciled in dances with their gentlemen callers, and that's how they got to know them — through a spin around the dancefloor.

"We're the modern day version of that type of dating," Sinner says, with less dancing but right in line with generating in-person conenctions.

A proud Houstonian, Sinner, whose background is in commercial real estate, was interested in bringing in local businesses from the start. DanceKard has several different offerings — all geared at driving in-person connections. Users can join the app to find events — not necessarily singles-specific events, although those are an option, but meetups where you know a certain number of singles will be in attendance.

"We focus a lot on group dating," Sinner explains. "That's something nobody does."

Singles, along with their single friends, can indicate on the app that they are interested in four, six, or eight-person dates, and see if their are other groups of friends looking to connect.

DanceKard also provides discounts and deals at its business partners' establishments. This drives business while also making deciding where to meet up a lot easier — and affordable.

"Everyone knows dating can get expensive — especially for the guys," Sinner says. "So, daters can go out on these dates and use a discount."

At the end of the day, DanceKard and Sinner are laser focused on creating relationships for their users. Modern dating has been defined by swiping on apps or drinking in bars, but that doesn't have to be your only options. DanceKard's events and opportunities will be more than just at bars — users can meet at the museum or the zoo and have an activity to connect with others over.

"People are looking for things other than drinking," she says. "They're realizing that if they are going to a bar where there are singles, that doesn't equate to a relationship."

For now, she's also focused on her hometown of Houston and is really being intentional about supporting local businesses and Houstonians themselves.

"Houston is a great opportunity," she says. "It's not about me, it's about this town. We have great people and great businesses."

Here's what companies are in the latest cohort for gBETA. Photo courtesy of gBETA

Early-stage accelerator announces 5 startups to its fall 2021 Houston cohort

ready to grow

An early-stage accelerator has picked its latest cohort of five Houston companies.

The Fall 2020 cohort of gBETA Houston includes:

AllIDoIsCook is founded by Tobi Smith and focused on exposing the world to Africa's cuisine by manufacturing gourmet food products delivered directly to customer doors and available at grocers. Since launching, AllIDoIsCook has built out a manufacturing facility, shipped over 8,000 boxes and generated $1.1 million in revenue all without outside funding.
Chasing Watts makes it easy for cyclists to coordinate or find rides with fellow riders in their area with its web-based and native application. The company has over 3,000 users and grew 135 percent from Q2 to Q3 in new ride views.
DanceKard, founded by Erica Sinner, is a new dating platform that connects individuals and groups with one another by bringing the date to the forefront of the conversation and making scheduling faster and easier with special promotions featuring local establishments. Since launching in August of 2021, DanceKard has over 170 users on the platform.
Dollarito is a digital lending platform that helps the low-income Hispanic population with no credit history or low FICO score access fair credit. Founded by Carmen Roman, Dollarito applies AI into banking, transactional and behavioral data to evaluate the repayment capability more accurately than using FICO scores. The company has1,000 users on their waitlist and plans to beta test with 100 or more customers in early 2022.
SeekerPitch, founded by Samantha Hepler, operates with the idea that jobseekers' past job titles and resumes are not always indicative of their true capabilities. Launched last month, SeekerPitch empowers companies to see who jobseekers are as people, and get to know them through comprehensive profiles and virtual speed interviews, and the company already has 215 jobseekers and 20 companies on the platform, with one pilot at University of Houston and three more in the pipeline.

The companies kicked off their cohort in person on October 18, and the program concludes on December 14 with the gBETA Houston Fall 2021 Pitch Night. At this event, each company will present their five-minute pitch to an audience of mentors, investors, and community members.

"The five founding teams selected for our gBETA Houston Fall 2021 cohort are tackling unique problems they have each experienced personally, from finding access to cultural foods, fitness communities and authentic dating experiences to challenges with non-inclusive financing and hiring practices," says Kate Evinger, director of gBETA Houston, in the release. "The grit and passion these individuals bring to their roles as founders will undoubtedly have a tremendous impact in the Houston community and beyond."

The accelerator has supported 15 Houston startups since it launched in Houston in early 2020. The program, which is free and hosted out of the Downtown Launchpad, is under the umbrella of Madison, Wisconsin-based international accelerator, gener8tor.

"Downtown Launchpad is an innovation hub like no other, and I am so proud of what it is already and what it will become," says Robert Pieroni, director of economic development at Central Houston Inc., in the release. "The five startups selected for the gBETA Houston Fall 2021 cohort are exploring new challenges that can become high-impact Houston businesses."

gBETA announced its plan to launch in Houston in September 2019. The program's inaugural cohort premiered in May and conducted the first program this summer completely virtually. The second cohort took place last fall, and the third ran earlier this year.

"These founders are building their companies and benefiting from the resources Downtown Launchpad provides," Pieroni continues, "and the proof is in the data – companies in these programs are creating jobs, growing their revenues and exponentially increasing their funding, which means these small starts up of today, working in Downtown Launchpad, are growing into the successful companies of tomorrow."

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Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

$1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
$922 million for the University of Houston System
$167 million for Texas Southern University
$10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
Created the Lake Houston Dredging and Maintenance District
Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

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