Kim Raath, CEO of Topl, and Leslie Goldman, general partner at The Artemis Fund, identified three challenges that female entrepreneurs face while going through the fundraising process. Photos courtesy

It's estimated that women make up only around 10 percent of decision makers in venture capital firms in the United States, and women-led companies only receive of a fraction of venture capital invested. And, stats aside, female entrepreneurs continue to face obstacles in the process that their male counterparts don't always share.

Kim Raath — co-founder and CEO of Topl, a Houston-based blockchain startup — and Leslie Goldman — general partner and co-founder of The Artemis Fund — discussed some of these obstacles at a virtual fireside chat for Dallas Startup Week. Here are the three challenges women face during fundraising, as Raath and Goldman discussed.

Balancing being realist with optimism

It's almost a chiche at this point — yet it still holds a great deal of truth — that women tend to be more honest than men when it comes to applying for jobs, for instance. Goldman says she's seen it plenty of times, especially when she was involved in corporate recruiting at one point in her career. Raath and Goldman agreed, women want to check off all the boxes on a requirements list.

"Men would apply if they could check just one box," Goldman says. "Women tend to be more realistic."

This trait, while noble, can be a disadvantage as it translates to the fundraising process.

Navigating unconscious bias

Raath says she's no stranger to discrimination for being a woman. In the chat, she tells a story of when she was a girl and the woman's track event she was supposed to run was canceled. She had her heart set on getting to nationals, so her father lobbied for her to get a chance to run in the boy's race. Eventually, they let her and she came in second place.

She continued to observe moments like this throughout her schooling, especially when she started studying male-dominated studies like economics and statistics — Raath now has a master's and a Ph.D from Rice University. When recently raising money for Topl's latest round, her observational and statistical mind picked up on something. Raath explains that there are two types of questions a VC might ask you — preventative vs. promotional. An example she gives for each is:

  • Preventative: "How many daily users do you have?"
  • Promotional: "How do you look to acquire users?"

"About three months in, I started realizing that I'm constantly getting these preventative questions. So, I did a little research," Raath says, explaining that she found that women are more likely to get these preventative questions. "Now, every preventative question I got, I started answering with a promotional answer."

It's the same unconscious bias as how a young male entrepreneur might be considered, "young and promising," while a woman with the same resume would be considered, "young and inexperienced."

Creating a supportive network

Raath and Goldman discussed the importance of women surrounding themselves with supportive networks made up of both women and men. On one hand, it's key to have fellow female entrepreneurs or investors who have been in your shoes before or whom you can give advice to — Raath says she created "woke woman wine nights" with her interns this summer.

On the other hand, having men in your network who can act as advocates — like Raath's father was as well as her male co-founders whom she says are great supporters — is crucial too.

"I have been surrounded by some amazing male counterparts," Raath says. "That's the other side of this is finding male champions."

Dallas Startup Week has pivoted to online panels and chats. Here's which ones Houston innovators shouldn't miss. Getty Images

Here's what Dallas Startup Week events Houston entrepreneurs should attend

where to be online

While a 4-hour trip up Interstate 45 might, in years prior, could have caused Houston entrepreneurs pause from attending the annual Dallas Startup Week, this year there's no excuse.

DSW is taking place online this year, and there are more than a couple virtual events Houston entrepreneurs need to attend. Here's which virtual events Houstonians should log on to.

Monday - The State of Fundraising in Texas

A panel of Texas-based venture experts will discuss the state of fundraising in Dallas and Texas as a whole. The panel includes:

  • Bryan Chambers, vice president of Accelerator & Investment Fund at Capital Factory
  • Cindy Revol, principal at Perot Jain
  • Laura Baldwin, managing director at Golden Seeds
  • Mike Marcantonio, principal at Live Oak Venture Partners

The virtual panel is at 9 am on Monday, August 31. More information.

Monday - Women Investing in Women

Two Houston women — Leslie Goldman, co-founder and general partner of The Artemis Fund, and Kim Raath, co-founder and CEO of Topl — are taking the virtual stage to discuss women in investing.

The virtual fireside chat is at 11 am on Monday, August 31. More information.

Monday - Innovating in co-working in a COVID-19 world

Trey Bowles and Delanie Majors from The DEC Network will host CEO and founder of Common Desk, Nick Clark, for a discussion on how COVID-19 affected co-working spaces and the entrepreneurs that used to work out of them.

The virtual panel is at 11:30 am on Monday, August 31. More information.

Tuesday - The Future of Marketing Post COVID-19

In 2020, the world changed as we know it. Hear from these marketing leaders about how the landscape will continue to change, and how you can be equipped to market your business during and after a pandemic. Panelists include:
  • Ramon Mendez, co-founder of Brand Army
  • Phil Lockhart, partner & chief digital officer of Credera
  • Michael Pratt, founder of Digital Fight Club
  • Laci McKinney, founder of The People's Voice Creative Agency
  • Jennifer Cho, executive vice president and general manager if Weber Shandwick

The virtual fireside chat is at 3:15 pm on Tuesday, September 1. More information.

Wednesday - Do You Really Know Your Customer: Customer Segmentation is Key to Success

Learn to keys to customer success from a panel of seven businesswomen, including:

  • Tracey Altman, principal, Altman Consulting
  • Sophia Johnson, founder & president at Alpha Business Images
  • Anjie Vichayanonda, founder & CEO of Leg Up Legal
  • Karen Jenkins, senior director and regional sales executive of Capital One
  • Kristy Alballero, co-founder & COO, IOOGO
  • Kristy Alballero is the co-founder and COO of IOOGO
  • Marty McDonald, CEO of Boss Women Media

The virtual fireside chat is at 10:15 am on Wednesday, September 2. More information.

Wednesday - How Smalls Can Win Big with Department of Defense

Learning to win government contracts can be a challenging task, yet millions of startups in the United States are thriving because of them. As a founder, entrepreneur, or just a curious individual, check out this session to learn about the keys to success in government contracting. Panelists include:

  • David Shaw, co-founder and chief commercialization officer at Astrapi
  • Steve Guengerich, senior adviser at the University of Texas at Dallas
  • Dave Copps, CEO of Hypergiant Sensory Sciences
  • Sam Riehn, business development at Long Capture & Contract Management

The virtual fireside chat is at 11 am on Wednesday, September 2. More information.

Thursday - The State of Corporate Venture

A panel of experts from some of the largest corporations in the world discuss how their companies work with and invest in startups. They will discuss ways to engage with them, what kinds of companies they look to invest in, and how investing has changed during a tumultuous 2020.

  • Duane Dankesreiter, senior vice president of Research and Innovation of Dallas Regional Chamber
  • Aman Sharma, partner of Capital One Ventures
  • Marisa Bertha, senior director at New Business Development & 7-Ventures, 7-Eleven
  • Jim Adler, founding managing director at Toyota Ventures

The virtual fireside chat is at 1:05 pm on Thursday, September 3. More information.

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Houston digital health platform Koda lands strategic investment

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Houston-based advance care planning platform Koda Health has added another investor to the lineup.

The company secured a strategic investment for an undisclosed amount from UPMC Enterprises, the commercialization arm of the University of Pittsburgh Medical Center. The funding is part of Koda's oversubscribed series A funding round that closed in October, according to a release.

"UPMC Enterprises’ investment is a meaningful signal, not just to Koda, but to the broader market," Dr. Desh Mohan, chief medical officer and co-founder of Koda Health, said in the news release. "It validates that health systems are ready to invest in infrastructure that makes advance care planning work the way it should: proactively, at scale, and with the human support that these conversations require. Having UPMC Enterprises as a strategic investor puts us in a unique position to prove what's possible."

Koda has raised $14 million to date, according to a representative from the company. Its series A round was led by Evidenced, with participation from Mudita Venture Partners, Techstars and the Texas Medical Center last year. At the time, the company said the funding would allow it to scale operations and expand engineering, clinical strategy and customer success. The company described the round as a "pivotal moment," as it had secured investments from influential leaders in the healthcare and venture capital space.

Koda Health, which was born out of the TMC's Biodesign Fellowship in 2020, saw major growth last year, as well, and now supports more than 1 million patients nationwide through partnerships with Cigna Healthcare, Privia Health, Guidehealth, Sentara, UPMC and Memorial Hermann Health System.

The company integrated its end-of-life care planning platform with Dallas-based Guidehealth in April 2025 and with Epic Systems in July 2025. It also won the 2025 Houston Innovation Award in the Health Tech Business category. Read more here.

New 'living pharmacy' biotech company launches out of Rice venture studio

fighting cancer

Rice University’s biotech venture studio RBL LLC has launched a new “living pharmacy” company, Duracyte, designed to make cancer treatment easier on patients.

Backed by an up to $45 million Advanced Research Projects Agency for Health (ARPA-H) award, Duracyte aims to commercialize implantable biohybrid pharmacy devices that are designed to produce therapeutic proteins inside the human body around the clock, replacing the need for regular injections and infusions for some cancer patients.

The company’s main platform is its Hybrid Advanced Molecular Manufacturing Regulator (HAMMR), a rechargeable, implantable device that can sense biological signals, monitor tumor environments and adjust therapeutic output in real time. HAMMR has wireless communication capabilities, which allow patients and clinicians to remotely monitor results through an app every five minutes and make changes to treatment plans without a hosptial visit. Additionally, the device can generate its own oxygen supply, which is key for the therapeutic cells’ survival.

“Biologic medicines such as monoclonal antibodies, cytokines and metabolic regulators already account for a significant share of modern therapeutics, but the way we deliver them today often requires frequent injections or infusions that can be demanding for patients and lead to inconsistent drug levels,” Daniel Anderson, MIT professor and co-founder of Duracyte, said in a news release. “Our vision is to enable a continuous, stable therapy by producing these medicines directly inside the body, which could improve treatment consistency, reduce side effects and ultimately transform how biologic therapies are delivered across many diseases.”

Duracyte’s first clinical trial is slated to begin by the end of 2026 and will focus on recurrent ovarian cancer. The Phase I study will build upon existing work on encapsulated cytokine pharmacy technology, and the company hopes that within a few years this treatment can reach clinical application.

The development of Duracyte is supported by ARPA-H's Targeted Hybrid Oncotherapeutic Regulation (THOR) project, which supports a multidisciplinary research consortium co-led by Omid Veiseh, a professor of bioengineering at Rice. The consortium also includes others at Rice, The University of Texas MD Anderson Cancer Center, Stanford University, Carnegie Mellon University, Northwestern University and the University of Houston, plus industry collaborators like Chicago-based CellTrans.

“What we are building is the culmination of years of progress in cell engineering, biomaterials and implantable device technology,” Veiseh added in the release. “By combining these advances with real-time sensing and adaptive drug delivery, we are working with the support of RBL to create a true ‘living pharmacy’ that can deliver continuous, precisely controlled biologic therapies and fundamentally change how these treatments reach patients.”

RBL launched in 2024 and is based out of Houston’s Texas Medical Center Helix Park. Duracyte is the third company launched by RBL, including Sentinel BioTherapeutics, a clinical-stage immunotherapy company developing localized cytokine therapies for solid tumors, and SteerBio, a regenerative medicine company targeting lymphedema.

“Duracyte exemplifies the kind of breakthrough that Houston’s ecosystem is built to produce,” Paul Wotton, managing partner of RBL LLC and co-founder of Duracyte, added in the release. “With world-class clinical infrastructure, exceptional engineering talent and initiatives like the Texas Biotech Task Force driving alignment across industry, investment and talent, this region is uniquely positioned to move the most ambitious ideas in medicine from concept to patient, faster than anywhere else.”