From a former astronaut to growing software company leaders, here are three innovators to know. Courtesy photos

This week's set of innovators to know are familiar with pivoting careers. All three had successful careers — from energy finance to space exploration — before jumping into a new field. And each set of prior experience prepared them for what they are doing today.

Alex Colosivschi, founder and CEO of Currux

Courtesy of Currux

Alex Colosivschi had a successful career in energy finance before he started his company, Currux. He was walking in his Rice Village neighborhood when the idea came to him. He realized that despite the green surroundings, he was choked by the smell of engine exhaust.

"I started with thinking about the future of energy and how the industry will adapt to a world of electric, autonomous and shared mobility, and the need to reduce CO2 emissions," he says.

Tim Kopra, partner at Blue Bear Capital

Courtesy of Blue Bear Capital

It might not be easy to connect the dots between Tim Kopra's NASA career and his current role at Blue Bear Capital, but for Kopra, it makes perfect sense.

"On face value, it may sound like an odd match, taking someone with a tech and operational background and putting them in venture, but quite frankly it feels very familiar to me because my career has really been focused on working on complex technology and operations with very small teams," Kopra says. "It's not just a theoretical understanding of the technology, but understanding how to use the technology and how it works."

Stuart Morstead, co-founder and COO of Arundo Analytics

Courtesy of Arundo Analytics

Stuart Morstead spent the bulk of his career in consulting, so he knows the importance of understanding the needs an industry has. He co-founded Arundo Analytics to address the analytical needs energy companies have on a regular basis.

Morstead says that most industrial companies that encounter issues with operations such as equipment maintenance "lack the data science and software capabilities to drive value from insights into their daily operations."

Arundo is growing — both from a funding standpoint as well as through its staff. The Houston company has big plans for its 2019.

This entrepreneur says the future of driving is using smart tech on a subscription-based business model. Pexels

This company’s machine learning programs are making driving in Houston safer — and cheaper

Vroom, Vroom

Two thousand years ago, in ancient Rome, the primary mode of transportation was an intelligent one: the horse. The Latin word "currus" was the inspiration for Alex Colosivschi when it came to naming his business, Currux.

"We chose this name because we believe in a future where cars and actually most modes of transportation will be intelligent, like horses," he explains. "And so it's a great name considering our focus on the future of mobility and machine learning."

The change from "s" to "x" at the end of the word allowed Colosivschi to trademark the name.

The entrepreneur, whose career was focused on energy finance until starting the new company in 2017, came up with the idea for Currux while walking in his Rice Village neighborhood. He realized that despite the green surroundings, he was choked by the smell of engine exhaust.

"I started with thinking about the future of energy and how the industry will adapt to a world of electric, autonomous and shared mobility, and the need to reduce CO2 emissions," he says.

His goal is an ambitious one: With Currux, Colosivschi hopes to not only reduce the cost and carbon footprint of owning a car, but also the accident rates. How? Currux itself is a long-term automobile subscription service. Colosivschi says to think of it as a long-term rental or a more flexible version of a lease. The car is delivered through an app and there is no commitment at the end of the subscription. Regular maintenance is included and the company is on the way to providing insurance, too.

It's also possible to share a car or fleet of cars with friends, assuring that your vehicle is only touched by people you know. This will be even more true when autonomous driving technology allows the car to go from subscriber to subscriber without a human in between.

"With the advent of digital shopping, we believe subscriptions will become the primary way that people get a car," Colosivschi predicts.

This will save clients money, but the ultimate goal is much bigger. Colosivschi wants to reduce air pollution. This will happen naturally with having fewer, mostly electric, cars on the road thanks to vehicle sharing, but another technology will also aid in the fight.

Currux Vision, which closely followed Currux in development, is a smartphone-based driver assistance program. It will help lower fuel consumption and reduce accident rates by "proactively coaching the driver on best driving practices," says Colosivschi.

"Just by slowing down and driving in a less aggressive manner, we can significantly reduce fuel consumption and more importantly prevent accidents from happening."

If you've driven or ridden in a Tesla, you've seen similar technology in action. Computer vision creates accident warnings and tracks how you handle your vehicle on the road. Yep, it's AI for your phone, which also incorporates GPS tracking, navigation and driver profile scoring.

"This set of functionalities normally require three or four different types of hardware and software systems and many thousands of dollars in expense per each car," explains Colosivschi.

But Currux Vision only requires that the user install the app, have a car-mounted phone holder with an unobstructed view of the road, and pay $4.99 each month for the technology.

Both these apps were created by Currux's own technical team, based mostly in Ukraine. As the company expands, Colosivschi has plans to significantly grow the Galleria-area Houston team, which is currently just a few employees strong.

But Colosivschi is ready for big growth. Currently, Currux is available only in Houston, but other U.S. cities will follow soon. As an energy industry lifer, the entrepreneur is also primed for significant changes not only to how we drive, but how we consume energy.

"The age of the internal combustion engine and automobile ushered in the age of oil. The age of lithium ion batteries, machine learning and digitization of transaction mediums similarly will have profound effects for both transportation and energy sectors," he predicts. He's confident that Currux can grow with those sea changes. And he's ready to help transform the world, starting with Houston.

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European spacecraft developer expands to Houston with U.S. business, new lab

houston hq

European aerospace manufacturer The Exploration Company has established its first U.S. entity and named Space City as its headquarters.

The company announced earlier this month that it has launched TEC Federal to support U.S. government customers and agencies, and to scale The Exploration Company's engineering operations in the country.

Mark Kirasich serves as president of TEC Federal. Kirasich most recently served as the senior director of human spaceflight at Blue Origin after a nearly 40-year career at NASA.

The Exploration Company is developing the reusable Nyx space vehicle. Nyx is designed to take off from any heavy launcher in the world. It will then dock at space stations, retrieve up to 3,000 kilograms of cargo, splash down and return the cargo to Earth. The company aims to make Nyx fully reusable for up to 10 missions, making it a more affordable and sustainable option for aerospace missions.

The Exploration Company completed a successful drop test of the spacecraft in May in the Mojave Desert. The company says Nyx is slated to perform its first flight demonstration in 2028.

In addition to launching the Houston business, The Exploration Company also opened its new Rapid Innovation Lab near Houston's NASA Johnson Space Center on Space Park Drive.

The Exploration Company opened its Rapid Innovation Lab earlier this month. Photo via LinkedIn

The Rapid Innovation Lab features a full-scale mockup of the future Nyx crew capsule as well as ongoing development and testing of the Nyx cargo capsule, according to the company.

The Exploration Company says the new lab will allow its engineers, designers, and operators to prototype and test crew interfaces. It will also support partnerships with NASA personnel and astronauts.

“Houston gives us direct access to the people and expertise that have built and operated human spaceflight systems for decades. We’re excited to invest and expand around that— engineers, operators, and astronauts working together and moving quickly towards building a crew capsule.” Hélène Huby, founder and CEO of The Exploration Company, said in a blog post.

According to The Houston Chronicle, The Exploration Company has about 30 employees in the Houston area.

The company was founded in 2021 by Huby, a French rocket scientist, and has raised more than $350 million in venture capital. It operates out of Germany, France, Luxembourg, Spain and Italy, with offices in the U.S. and the United Arab Emirates. It is also developing a reusable, high-thrust rocket engine known as Storm.

UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.