Corporations can do more than just throw money at innovation efforts. Photo via Getty Images

I vividly remember, it was a typical Tuesday at Houston Exponential, and I’m sipping maybe my third coffee of the morning when the phone rings.

On the line is yet another hopeful voice from a newly minted innovation group at a "big company." They lay out their vision: “We’ve got this new innovation group! It’s me — a tech enthusiast who’s been yelling into the corporate void about needing to shake things up for the last two decades — plus a data scientist who loves numbers more than people, and a procurement guy who… well, procures stuff. And here’s the kicker: they’ve handed us $60 million to put to work. But here’s the catch — this treasure needs to be turned into a groundbreaking innovation that will dazzle the C-Suite, in about six months.”

I chuckle then sigh, because I’ve heard this story not once or twice, but about a dozen times over. And unfortunately, each of those grand plans crashed faster than a shooting star burning out over the Texas night sky — brilliant, swift, and leaving us wondering what might have been. Why? Well, let’s dig into some observations from my time working with institutional innovators from around the world and uncover just why throwing money at innovation like confetti at a wedding isn’t the quick fix big companies hope it will be.

The big miss here is a deep understanding of and ability to articulate the challenges. Innovation isn’t a highway where you can just press the gas and speed straight to Mt. Scale. It’s more like a winding country road with breathtaking views, unexpected potholes, and the occasional bewildered chicken crossing your path. For institutional innovators — the brave souls charting the course through this ever-changing landscape — the journey is filled with excitement, challenges, and the promise of discovery.

In my first hand experience mentoring over 500 startups and corporations, I’ve seen that the magic of innovation doesn’t come from a deep-pocketed budget but from a deep understanding of the problems we aim to solve. If you can view challenges through a kaleidoscope of perspectives, not just through the monochrome lens of one industry, you find the alternate routes that, while not exactly shortcuts, do keep you from turning down dark alleys and dead ends. A key observation here is that solutions to hard problems often lie in adjacent industries.

For example, consider how biomimicry has led to inventions like Velcro, inspired by burrs' ability to stick to animal fur, or how bullet trains in Japan were designed to mimic the kingfisher's beak for better aerodynamics. These are just a few examples of how solutions to complex problems often reside right in front of us or in the industry next door. Right here in Houston, Pumps & Pipes is a glowing example of how experts from Energy, Life Science and Space converge on similar problem sets with wildly different perspectives and applications.

Imagine if the engineers at NASA sat down for tacos with teachers from the local high school, or if doctors brainstormed with video game designers over a game of pickleball. Sounds fun, right? But it’s also where the magic happens. When we step out of our industry bubbles, we find that the solutions to our biggest problems often come from the most unexpected places.

So how do we begin to find these solutions? It all starts with a clear and clearly articulated challenge statement.

A crucial factor in encouraging organizations to look beyond traditional industry boundaries is to foster a deep understanding of problem-solution fit (you can read more about Problem - Solution fit in my last article here) and that means a deep understanding of the Problem. By guiding problem holders to dig deep into the nuances of the problems they aim to address, we expand their perspective. Once a comprehensive grasp of the problems are established, new pathways for solutions organically emerge. To do this you must broaden the collective thinking to the point where solutions from other industries become not just viable but often the most effective approach. My favorite quote on this subject is that “people don’t need a ¼ inch drill bit, they need a ¼ inch hole, and really they don’t need a ¼ hole, they need to hang a picture and when framed in that context, a command strip is more effective at solving the problem.”

So how do we do this? It’s easy, just continuously ask "why" or “why does this matter to your customer” to peel back the layers of the initial problem statements to reveal underlying causes or first principles. Ok this is actually much harder than it sounds but when organizations are guided through exercises to distill their challenges into first principles and more universal problem statements, a transformation occurs, resulting in several benefits:

  1. Expanding Solution Horizons: By elevating the problem discussion beyond industry-specific issues, the range of potential solutions widens remarkably.
  2. Universal Problem Statements: Restating the issues into more universal terms unlocks innovative approaches and solutions previously unseen.
  3. Enhanced Solution Fit and Success Probability: This reframing leads to solutions that are not only more fitting but also stand a higher chance of successfully being adopted and integrated and thus resolving the underlying issues.
  4. Increased Buy-In: These solutions are and are perceived as more novel and thus receive increased buy-in across the organization when moving towards adoption.

The critical lesson here is the power of abstracting the problem. By pulling back from the immediate and specific issues and reinterpreting them into broader, more universally applicable challenges, we can tap into a richer vein of solutions. This approach not only broadens the scope of potential innovations but also increases the alignment and effectiveness of the solutions we pursue.

The art of crafting challenge statements that are both broad enough to inspire innovative thinking and specific enough to be actionable is crucial. These statements serve as beacons, guiding both internal and external innovation efforts towards solutions that are not bound by conventional industry norms. By framing challenges in a way that invites diverse perspectives, organizations unlock innovative solutions that transcend traditional boundaries, fostering a more expansive and inclusive approach to problem-solving.

Turning lofty ambitions into tangible results begins with understanding that innovation isn’t just about flashy gadgets or the latest buzzwords. It’s about solving real problems for real people. This means rolling up our sleeves, listening intently, and sometimes realizing that the solution isn’t a high-tech wonder but perhaps something as simple and elegant as a command strip instead of a hole in the wall.

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Jon Nordby is managing partner at Anthropy Partners, a Houston-based investment firm, and professor of entrepreneurship at the University of Houston.

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UH lands $4M NIH grant to study early signs of autoimmune disease

NIH funding

The University of Houston recently received a $4 million National Institutes of Health grant to support a 10-year longitudinal study to identify the earliest biological markers of autoimmune disease.

Led by Chandra Mohan, the Hugh Roy and Lillie Cranz Cullen Endowed Professor of Biomedical Engineering, the study aims to examine what causes Systemic Autoimmune Rheumatic Diseases (SARDs) and to identify targets for future treatments. The study will be carried out in collaboration with Dr. Karen Costenbader at Harvard Medical School, Boston.

SARDs include conditions like rheumatoid arthritis, systemic lupus erythematosus, Sjögren’s syndrome and systemic sclerosis—all are considered chronic diseases currently without a cure. Autoimmune diseases affect over 30 million people globally, according to UH.

SARDs occur when the body’s immune system attacks healthy, non-threatening tissues and organs. According to UH, in these diseases, the body often attacks nuclear antigens, creating anti-nuclear autoantibodies, which can be early detection signs for SARDs in more than 50 percent of patients, Mohan says.

Researchers will study blood samples and environmental exposure over the 10 years to better understand anti-nuclear autoantibodies.

“Collectively, these studies will help identify the genetic, environmental and cellular factors that are operative at the two steps of SARD development, namely the emergence of anti-nuclear autoantibodies and disease onset,” Mohan said in a news release. “ More importantly, these studies will highlight functional molecular pathways and mechanisms that may be operative at each step."

Mohan predicts that looking at SARDs’ shared characteristics, rather than each disease individually, could help identify more treatment methods.

“Individual SARDs have been examined in silos without an attempt to discern shared underlying features at the molecular level,” he added in the release. “Current understanding of the initial (and likely shared) origins of SARDs is only rudimentary but urgently needed to develop means for prevention and treatment.”

Earlier this year, UH also received an $11 million NIH grant to conduct a first-of-its-kind study of early language development in children ages 18 to 24 months. Read more here.

New Texas Stock Exchange officially begins trading in Dallas

Welcome to Y'all Street

Two-step aside, New York Stock Exchange and Nasdaq. The Dallas-based Texas Stock Exchange, nicknamed Y’all Street, just kicked off live trading with five stocks — and lots of Lone Star ambition.

“The Texas Stock Exchange aims to revitalize competition for [stock] issuers, establish the premier venue for listings, and create a world-class trading platform for all market participants,” the exchange says in a fact sheet.

The exchange — whose Texas-influenced nickname is a nod to New York City’s Wall Street — has collected at least $275 million in investments. The roughly 90 financial backers of TXSE include Bank of America, BlackRock, Charles Schwab, Citadel Securities, Dell Family Office, Fortress, Goldman Sachs, and JPMorgan Chase.

Representatives of TXSE couldn’t be reached for comment. On its website, the exchange calls itself “the most well-capitalized equities exchange to ever be approved” by the U.S. Securities and Exchange Commission (SEC).

Not to be outdone, NYSE has launched Dallas-based NYSE Texas and Nasdaq has expanded its presence in Dallas.

Y’all Street adds to Dallas-Fort Worth’s rising status as a major hub for financial services, with The Wall Street Journal naming North Texas the country’s second biggest financial hub after New York City.

“A homegrown national exchange means more jobs, more investment, and more growth opportunities for businesses and communities across the Lone Star State,” Gabriela von zur Muehlen, senior vice president and chief policy officer at the Texas Association of Business, told The Texas Tribune.

Bulent Temel, an associate professor of practice in economics at the University of Texas at San Antonio, told Texas Standard that TXSE “is going to boost the credibility of the Texas economy.”

Texas’ estimated gross domestic product (GDP), a yardstick for the size of an economy, climbed to a record-setting $2.9 trillion in 2025, making it the state with the second highest GDP after California. DFW’s estimated GDP in 2023 stood at $744.6 billion, eclipsing the GDP of many countries.

“The center of gravity for American capitalism is now headquartered in the Boom Belt,” Abbott proclaimed in April, referring to an 11-state region (including Texas) in the South and Southeast that’s seeing tremendous economic and population growth. “The Texas Stock Exchange is the natural extension of that capitalism. It ensures that capital markets will reflect the quadrant that is driving American growth.”

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This article originally appeared on CultureMap.com.

Orion vehicle manager reflects on Artemis II, looks to 2028 moon mission

Q&A

Humanity is finally headed back to the moon after more than half a century. This year's launch of the Artemis II mission in the Orion spacecraft put four crew members in lunar orbit and tested the new ship developed by Lockheed Martin.

Everything went smoothly, safely returning astronauts home, but there is always room to improve. InnovationMap chatted via email with Orion vehicle manager Branelle Rodriguez, shortly after a talk at The Ion, for insight on how Orion might perform in the future as the next lunar landing approaches in early 2028.

InnovationMap: How satisfied are you with the way Orion operated on this past mission?

Branelle Rodriguez: Orion performed exceptionally well during Artemis II, successfully demonstrating critical spacecraft capabilities, including life support systems, displays and controls, and executing manual piloting operations. Artemis II brought humans back to the moon, achieving key exploration and scientific imagery, while validating systems essential for future Artemis missions.

IM: What is the most important thing you learned about improving Orion for the next mission?

BR: The Artemis II mission provided invaluable insights into crew operations and spacecraft performance in a deep-space environment. With every mission, NASA applies lessons learned to continuously improve Orion’s operations, validate design and ensure mission readiness. Artemis II offered our first opportunity to evaluate several new systems and gain a deeper understanding of what it is like for astronauts to live and work inside the spacecraft. The operational, technical and human factors data collected are being integrated across the program to refine future missions, reduce risk and enhance overall mission success.

IM: How has Orion helped the mission to explore space?

BR: Orion is one of NASA’s foundational elements for human deep space exploration—not only supporting the mission but serving as a core component of it. It is currently the only spacecraft capable of carrying crew on deep space missions and returning them safely to Earth from the high speeds required from the vicinity of the moon. No other spacecraft has the technology to endure the extremes that come with human deep-space travel, such as advanced environmental and life support, navigation, communications, radiation shielding, and the world’s largest ablative heat shield to protect the astronauts during reentry into Earth’s atmosphere. Orion has already taken astronauts to explore space farther than ever before—252,756 miles from Earth— and will carry crews to the moon on future missions to explore the lunar South Pole region. The astronauts’ observations, samples, and data collected on these future missions will expand our understanding of our solar system and home planet.

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This conversation has been edited for brevity and clarity.