2 Houston high schools rank among America's top 100 in 2024, says U.S. News

best in class

Houston is home to two of the highest-ranked schools in the country. Photo via Getty Images

Two Houston high schools are dominating U.S. News and World Report's prestigious annual list of the country's best public high schools.

The 2024 rankings from U.S. News, released April 23, put Houston ISD’s Carnegie Vanguard High School at No. 31 nationally (up from No. 35 last year and No. 40 in 2022) among the country’s best high schools. The school also ranks No. 248 nationally among the best STEM (science, technology, engineering, and math) high schools and No. 12 among the best magnet high schools.

Meanwhile, DeBakey High School for Health Professions ranks No. 70 nationally among the best high schools (down from No. 66 last year and No. 50 in 2022) and No. 19 among best magnet high schools. DeBakey ranked No. 426 nationally among best STEM high schools.

Topping the national list for 2024 is the BASIS Peoria Charter School in Peoria, Arizona.

Each year, U.S. News evaluates about 18,000 high schools on six factors: college readiness, reading and math proficiency, reading and math performance, underserved student performance, college curriculum breadth, and graduation rates.

“The 2024 Best High Schools rankings offer a starting point for parents to understand a school’s academic performance, whether it’s a prospective school or one that their child is already attending,” said LaMont Jones, Ed.D., the managing editor of education at U.S. News, in a release. “Accessible data on our high schools can empower families across the country as they navigate today’s educational environment and plan for the future.”

Elsewhere in Texas
Around the state, these Texas high schools also made it into the top 100 nationally:

  • Dallas ISD's The School for the Talented and Gifted, No. 6 (unchanged from last year). No. 21 nationally among the best STEM high schools, and No. 3 among the best magnet high schools.
  • Dallas ISD's Irma Lerma Rangel Young Women's Leadership School, No. 23 (down from No. 18 last year) and No. 10 nationally among the best magnet high schools.
  • Dallas ISD's Science and Engineering Magnet School, No. 29 nationally among the best high schools (down from No. 23 last year), No. 37 nationally among the best STEM high schools, and No. 11 nationally among the best magnet high schools.
  • Grand Prairie ISD's Collegiate Institute, No. 30 (up from No. 188 last year). No. 6 nationally among best charter high schools.
  • Austin ISD’s Liberal Arts and Science Academy, No. 38 (down from No. 32 last year and No. 34 in 2022). No. 34 nationally among the best STEM high schools.
  • BASIS San Antonio - Shavano Campus, No. 64 (up from No. 81 last year and No. 77 in 2022). No. 76 nationally among the best STEM high schools and No. 13 nationally among the best charter high schools.
  • Brownsville ISD's Early College High School, No. 71 (up from No. 229 last year).
  • Dallas ISD’s Judge Barefoot Sanders Law Magnet, No. 85 (up from No. 93 last year and No. 48 in 2022) . No. 21 nationally among the best magnet high schools.

When broken down just to Texas schools, Houston's Carnegie Vanguard High School (No. 5) and DeBakey High School for Health Professions (No. 8) are both in the top 10 best-rated public high schools in Texas this year, U.S. News says.

Other Houston-area schools that rank among Texas' 100 best are:

  • No. 24 – Kinder High School for Performing and Visual Arts, Houston ISD
  • No. 25 – Challenge Early College High School, Houston ISD
  • No. 29 – Young Women's College Prep Academy, Houston ISD
  • No. 32 – Eastwood Academy, Houston ISD
  • No. 37 – Harmony School of Innovation - Katy, Katy
  • No. 40 – Kerr High School, Alief ISD, Houston
  • No. 43 – Houston Academy for International Studies, Houston ISD
  • No. 47 – East Early College High School, Houston ISD
  • No. 59 – Clear Horizons Early College High School, Clear Creek ISD, Houston
  • No. 61 – Seven Lakes High School, Katy ISD
  • No. 63 – Early College Academy at Southridge, Spring ISD, Houston
  • No. 68 – KIPP Houston High School, Houston
  • No. 70 – North Houston Early College High School, Houston ISD
  • No. 71 – Victory Early College High School, Aldine ISD, Houston
  • No. 75 – Tompkins High School, Katy ISD
  • No. 76 – Clements High School, Fort Bend ISD, Sugar Land
  • No. 82 – Sharpstown International School, Houston ISD
  • No. 85 – Tomball Star Academy, Tomball ISD
  • No. 89 – Westchester Academy for International Studies, Spring Branch ISD, Houston
  • No. 95 – Harmony School of Innovation - Sugar Land, Sugar Land
  • No. 97 – Harmony School of Discovery - Houston, Houston
  • No. 98 – Energy Institute High School, Houston ISD

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Houston is home to a few of the highest-ranked high schools in the nation. Getty Images

3 heroic Houston high schools rank among top 100 in America, says U.S. News

super schools

Three Houston high schools are continuing their streak of top appearances on a prestigious annual list of the country's best public high schools.

The 2023 rankings from U.S. News & World Report, released August 29, put Houston ISD’s Carnegie Vanguard High School at No. 35 nationally (up from No. 40 last year) among the country’s best high schools. The school also ranks No. 248 nationally among the best STEM (science, technology, engineering, and math) high schools and No. 12 among the best magnet high schools.

Also in the top 100 are two other Houston ISD high schools.

DeBakey High School for Health Professions ranks No. 66 nationally among the best high schools (down from No. 50 last year) and No. 18 among best magnet high schools for the second consecutive year.

Young Women's College Prep Academy comes in No. 94 nationally among the best high schools (up from No. 148 last year), and No. 26 among best magnet high schools.

Topping the national list for 2023 is the Early College at Guilford in Greensboro, North Carolina.

Each year, U.S. News evaluates about 18,000 high schools on six factors: college readiness, reading and proficiency, reading and math performance, underserved student performance, college curriculum breadth, and graduation rates.

"Having access to a strong high school program is paramount for students as they face an ever-changing world," said U.S. News' managing editor of education Liana Loewus in a release. "Making data on our high schools available helps parents ensure their child is in the educational environment that best sets them up to thrive."

Elsewhere in Texas
Around the state, these Texas high schools also made it into the top 100 nationally:

  • Dallas ISD's The School for the Talented and Gifted, No. 6 (up from No. 8 last year and No. 13 in 2021). No. 8 nationally among the best STEM high schools for the second consecutive year and No. 2 among the best magnet high schools (up from No. 4 last year).
  • Dallas ISD's Irma Lerma Rangel Young Women's Leadership School, No. 18 (up from No. 20 last year) and No. 8 nationally among the best magnet high schools for the second consecutive year.
  • Dallas ISD's Science and Engineering Magnet School, No. 23 nationally among the best high schools (down from No. 22 last year), No. 24 nationally among the best STEM high schools (down from No. 7 last year), and No. 2 nationally among the best magnet high schools (up from No. 10 in 2022).
  • Austin ISD’s Liberal Arts and Science Academy, No. 32 (up from No. 34 last year and No. 41 in 2021). No. 34 nationally among the best STEM high schools (up from No. 70 in 2022).
  • BASIS San Antonio - Shavano Campus, No. 81 (down from No. 77 last year and No. 102 in 2021). No. 41 nationally among the best STEM high schools (down from No. 25 in 2022) and No. 17 nationally among the best charter high schools.
  • Dallas ISD's Trinidad Garza Early College at Mt. View, No. 91 (up from No. 118 last year).
  • Dallas ISD’s Judge Barefoot Sanders Law Magnet, No. 93 (down from No. 48 last year and No. 59 in 2021) . No. 25 nationally among the best magnet high schools (down from No. 17 in 2022).
  • Austin ISD's Richards School for Young Women Leaders, No. 95 (up from No. 128 last year).

When broken down just to Texas schools, Houston's Carnegie Vanguard High School (No. 5), DeBakey High School for Health Professions (No. 6), and Young Women's College Prep Academy (No. 10) are all in the top 10 best-rated public high schools in Texas this year, U.S. News says.

Other Houston-area schools that rank among Texas' 100 best are:

  • No. 12 – Kinder High School for Performing and Visual Arts, Houston ISD
  • No. 21 – Challenge Early College High School, Houston ISD
  • No. 24 – Kerr High School, Alief ISD, Houston
  • No. 29 – Eastwood Academy, Houston ISD
  • No. 37 – YES Prep - Southwest, Houston
  • No. 39 – Harmony School of Innovation - Katy, Katy
  • No. 40 – North Houston Early College High School, Houston ISD
  • No. 42 – Clear Horizons Early College High School, Clear Creek ISD, Houston
  • No. 46 – Seven Lakes High School, Katy ISD
  • No. 53 – Victory Early College High School, Aldine ISD, Houston
  • No. 54 – YES Prep - Southeast, Houston
  • No. 57 – East Early College High School, Houston ISD
  • No. 58 – Houston Academy for International Studies, Houston ISD
  • No. 64 – YES Prep - East End, Houston
  • No. 69 – Tomball Star Academy, Tomball ISD
  • No. 72 – Early College Academy at Southridge, Spring ISD, Houston
  • No. 73 – Tompkins High School, Katy ISD
  • No. 75 – Clements High School, Fort Bend ISD, Sugar Land
  • No. 82 – YES Prep - North Central, Houston
  • No. 83 – Sharpstown International School, Houston ISD
  • No. 93 – YES Prep - North Forest, Houston
  • No. 95 – YES Prep - West, Houston
  • No. 97 – High School for Law and Justice, Houston ISD

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St. John's School is ranked the No. 2 private high school in Texas. St. John's School.org

7 prestigious Houston-area high schools rank among best in Texas for 2021

report card

Several Houston-area school are among the top of their class among public and private high schools in Texas.

New rankings from education website Niche put three local institutions among the top public high schools in the state and four among the top private high schools in the state.

Carnegie Vanguard High School (in Houston ISD) leads the area best public high schools, while our prestigious St. John's School leads the private academies.

Niche ranks public high schools based on factors such as state test scores, college readiness, graduation rates, SAT/ACT scores, teacher quality, and Niche user ratings.

Meanwhile, Niche ranks private high schools based on factors like SAT/ACT scores, quality of colleges that students consider, student-teacher ratio, and Niche user ratings.

"Our 2022 rankings come at a time when so many parents are curious about the different options for their children's education, including some they may never have considered before," Luke Skurman, founder and CEO of Niche, says in a news release.

Other local schools also ranked well:

  • Top-ranked School for the Talented and Gifted (Dallas ISD).
  • Second-ranked Liberal Arts & Science Academy (Austin ISD).
  • Third-ranked School of Science and Engineering (Dallas ISD).
  • Fourth-ranked Westlake High School (Eanes ISD).
  • Fifth-ranked Carnegie Vanguard High School (Houston ISD).
  • Sixth-ranked DeBakey High School for Health Professions (Houston ISD).
  • Seventh-ranked Carroll Senior High School (Carroll ISD).
  • Eighth-ranked Westwood High School (Round Rock ISD).
  • Ninth-ranked Kinder High School for the Performing and Visual Arts (Houston ISD).
  • 10th-ranked Vandegrift High School (Leander ISD).

The top private high schools in Texas are:

  • Top-ranked St. Mark's School of Texas in Dallas.
  • Second-ranked St. John's School in Houston.
  • Third-ranked Greenhill School in Addison.
  • Fourth-ranked The Hockaday School in Dallas.
  • Fifth-ranked St. Stephen's Episcopal School in Austin.
  • Sixth-ranked The John Cooper School in The Woodlands.
  • Seventh-ranked The Awty International School in Houston.
  • Eighth-ranked Keystone School in San Antonio.
  • Ninth-ranked Cistercian Preparatory School in Irving.
  • 10th-ranked The Kincaid School in Houston.

As for the best school districts in Texas, they are:

  • Top-ranked Eanes ISD in Austin.
  • Second-ranked South Texas ISD in Mercedes.
  • Third-ranked Highland Park ISD in Dallas.
  • Fourth-ranked Carroll ISD in Southlake.
  • Fifth-ranked Coppell ISD in Coppell.
  • Sixth-ranked Lovejoy ISD in Allen.
  • Seventh-ranked Frisco ISD in Frisco.
  • Eighth-ranked Argyle ISD in Argyle.
  • Ninth-ranked Grapevine-Colleyville ISD in Grapevine.
  • 10th-ranked Allen ISD in Allen.
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Here's what Houston schools have been lauded for training the city's future leaders. Photo by skynesher/Getty Images

These are Houston's 4 best high schools in 2021, says recent report

REPORT CARD

t's report card time, and four Houston high schools have made the grade, earning top 100 spots in this year's prestigious U.S. News & World Report rankings of the Best U.S. High Schools. One even merited a special distinction.

Houston's Carnegie Vanguard High School ranked highest on the list at No. 42. The school is ranked fifth within Texas. The Advanced Placement coursework participation rate there is 100 percent; total minority enrollment is 77 percent, and 31 percent of students are economically disadvantaged.

Following close behind is the prestigious DeBakey High School for Health Professions at No. 46 overall. The renowned medical prep school boasts an AP participation rate of 98 percent, total minority enrollment is 88 percent, and 44 percent of students are economically disadvantaged.

Farther down the list is Challenge Early College High School, at No. 89 overall. The AP participation rate here is 100 percent, total minority enrollment is 92 percent, and 76 percent of students are economically disadvantaged.

At No. 97 overall is Young Women's College Prep Academy. The AP participation rate here is 100 percent. The total minority enrollment is 97 percent, and nearly all students — some 96 percent — are economically disadvantaged.

The 2021 edition is U.S. News' most comprehensive survey yet, with the consumer advice outlet evaluating more than 17,800 public high schools on how well they serve all of their students, regardless of economic or ethnic background.

To determine rankings, they focus on six factors: college readiness, reading and math proficiency, reading and math performance, underserved student performance, college curriculum breadth, and graduation rates. College readiness specifically measures participation and performance on Advanced Placement and International Baccalaureate exams.

Notably, the data used in this edition is from the 2018-2019 academic school year, so it was not affected by the COVID-19 pandemic.

"Families can use the Best High Schools rankings to see how schools compare at the national, state and local level on factors like graduation rates and college readiness," said Anita Narayan, managing editor of Education at U.S. News, in a statement. "The rankings also provide insight into academic performance among underserved groups showing how well schools are supporting these students."

Eight more Texas schools also appear on the national top 100 list:

  • No. 13, School for the Talented and Gifted, Dallas
  • No. 15, Irma Lerma Rangel Young Women's Leadership School, Dallas
  • No. 39, The Science and Engineering Magnet School, Dallas
  • No. 41, Liberal Arts and Science Academy, Austin
  • No. 42, Carnegie Vanguard High School, Houston
  • No. 46, DeBakey High School for Health Professions, Houston
  • No. 59, Judge Barefoot Sanders Law Magnet, Dallas
  • No. 68, IDEA Frontier College Preparatory, Brownsville
  • No. 89, Challenge Early College High School, Houston
  • No. 96, Health Careers High School, San Antonio
  • No. 97, Young Women's College Prep Academy, Houston
  • No. 98, Ann Richards School for Young Women Leaders, Austin

Just over the top 100 threshold is Grand Prairie Fine Arts Academy, coming in at No. 101.

Texas had 1,524 schools ranked this year, of which 42 placed in the top 5 percent, 79 in the top 10 percent, and 157 in the top 25 percent nationally.

Statewide, the top 10 highest ranking schools were:

  1. The School for the Talented and Gifted (TAG), Dallas
  2. Irma Lerma Rangel Young Women's Leadership School, Dallas
  3. Science and Engineering Magnet School (SEM), Dallas
  4. Liberal Arts and Science Academy (LASA), Austin
  5. Carnegie Vanguard High School, Houston
  6. DeBakey High School for Health Professions, Houston
  7. Judge Barefoot Sanders Law Magnet, Dallas
  8. IDEA Frontier College Preparatory, Brownsville
  9. Challenge Early College High School, Houston
  10. Health Careers High School, San Antonio

So, which school throughout the country ranks as this year's valedictorian? Thomas Jefferson High School for Science and Technology in Alexandria, Virginia was deemed the best in the country, as well as among magnet schools. Read the full report and search for schools here.

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This article originally ran on CultureMap.

Three Houston schools crack the top 10 high schools in Texas. Photo by Klaus Vedfelt/Getty Images

Here's what Houston high schools shine brightest in the state, according to a new report

A+ education

A couple of Texas schools have been working hard on extra credit, or so says the latest ranking by U.S. News & World Report. Its list of the Best U.S. High Schools, released April 21, includes two Dallas public schools in the national top 10, with several other Texas learning institutions popping up further down.

The School for the Talented and Gifted earns a coveted No. 6 spot, followed by Irma Lerma Rangel Young Women's Leadership School at No. 10. Last year's No. 12, Science and Engineering Magnet School, slips slightly to No. 17 this year. All three are in the Dallas ISD.

On a state level, this trio takes the top three spots. Houston's DeBakey High School for Health Professions is No. 4 in Texas, with Carnegie Vanguard High School at No. 6 and Eastwood Academy at No. 10.

This is the most expansive edition yet, with the consumer advice outlet evaluating more than 17,700 public high schools on how well they serve all of their students, regardless of economic or ethnic background.

The methodology focuses on six factors: college readiness, reading and math proficiency, reading and math performance, underserved student performance, college curriculum breadth, and graduation rates. College readiness measures participation and performance on AP and IB exams.

"The Best High Schools rankings provide the most comprehensive, data-based information on nearly every public high school in the country," says Anita Narayan, managing editor of education at U.S. News. "Families can use this information to see how their local schools compare on graduation rates and state assessments, as well as academic performance by students who are traditionally underserved — those who are black, Hispanic, or from low-income households."

Also appearing on the national list are six more Texas schools within the top 100:

  • No. 29, DeBakey High School for Health Professions, Houston ISD
  • No. 34, Liberal Arts and Science Academy, Austin ISD
  • No. 44, Carnegie Vanguard High School, Houston ISD
  • No. 61, Early College High School, Laredo ISD
  • No. 82, Young Women's Leadership Academy, Fort Worth ISD
  • No. 91 Basis San Antonio- Shavano Campus, Basis Texas Castle Hills

The report also shows that the highest-ranked schools are scattered throughout the country, showing that the best schools are not concentrated in any one geographic area. Nine different states are represented among the top 10 schools. More broadly, the top 100 schools span 29 states.

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This article originally ran on CultureMap.

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Intuitive Machines to buy satellite maker Lanteris for $800M

space deal

Houston-based aerospace company Intuitive Machines has agreed to buy satellite manufacturer Lanteris Space Systems for $800 million from private equity firm Advent International.

Intuitive Machines co-founder, president and CEO Steve Altemus said the combined revenue of his company and Palo Alto, California-based Lanteris exceeded $850 million as of Sept. 30, and their backlog of orders totaled $920 million.

Until recently, Lanteris operated as Maxar Space Systems. Its origins date back to 1957.

The deal—comprising $450 million in cash and $350 million in Class A shares of Intuitive Machines stock—is expected to close in the first quarter of 2026.

The acquisition “marks the moment Intuitive Machines transitions from a lunar company to a multi-domain space [company], setting the pace for how the industry’s next generation will operate,” Altemus said.

Altemus said the acquisition would enable Intuitive Machines to better compete for Earth orbit, lunar, Mars and deep space projects. Among the opportunities that would open up thanks to the Lanteris deal are the proposed Golden Dome missile defense system and a large lunar lander capable of carrying astronauts, he said.

“The new Intuitive Machines will combine rapid innovation and precision spacecraft production to meet the growing demand for responsive, high-reliability space infrastructure and services,” Altemus said.

Intuitive Machines, founded in 2013, develops lunar landers and provides aerospace services. In 2024, it became the first U.S. company to land a spacecraft on the moon in half a century.

Altemus said Intuitive Machines is already building three satellites for NASA’s near-space network, and it might upsize two more satellites now that it plans to buy Lanteris.

Aside from satellites, Lanteris is developing the power and propulsion element for NASA’s Gateway, a lunar orbiting command module that will support Artemis missions and deep space exploration.


Lanteris was a division of Maxar Technologies, which Advent and minority investor British Columbia Investment Management took private in a 2023 deal valued at $6.4 billion

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Meet 6 mentors who are helping the Houston startup scene flourish

meet the finalists

Few founders launch successful startups alone — experienced and insightful mentors often play an integral role in helping the business and its founders thrive.

The Houston startup community is home to many mentors who are willing to lend an ear and share advice to help entrepreneurs meet their goals.

The Mentor of the Year category in our 2025 Houston Innovation Awards will honor an individual like this, who dedicates their time and expertise to guide and support budding entrepreneurs. The award is presented by Houston City College Northwest.

Below, meet the six finalists for the 2025 award. They support promising startups in the medical tech, digital health, clean energy and hardware sectors.

Then, join us at the Houston Innovation Awards this Thursday, Nov. 13 at Greentown Labs, when the winner will be unveiled. The event is just days away, so secure your seats now.

Anil Shetty, InformAI

Anil Shetty serves as president and chief medical officer for biotech company Ferronova and chief innovation officer for InformAI. He's mentored numerous medical device and digital health companies at seed or Series A, including Pathex, Neurostasis, Vivifi Medical and many others. He mentors through organizations like Capital Factory, TMC Biodesign, UT Venture Mentoring, UTMB Innovation and Rice's Global Medical Innovation program.

"Being a mentor means empowering early-stage innovators to shape, test, and refine their ideas with clarity and purpose," Shetty says. "I’m driven by the opportunity to help them think strategically and pivot early before resources are wasted. At this critical stage, most founders lack the financial means to bring on seasoned experts and often haven’t yet gained real-world exposure. Mentorship allows me to fill that gap, offering guidance that accelerates their learning curve and increases the chances of meaningful, sustainable impact."

Jason Ethier, EnergyTech Nexus

Jason Ethier is the founding partner of EnergyTech Nexus, through which he has mentored numerous startups and Innovation Awards finalists, including Geokiln, Energy AI Solutions, Capwell Services and Corrolytics. He founded Dynamo Micropower in 2011 and served as its president and CEO. He later co-founded Greentown Labs in Massachusetts and helped bring the accelerator to Houston.

"Being a mentor means using my experience to help founders see a clearer path to success. I’ve spent years navigating the ups and downs of building companies, struggling with cash flow, and making all the mistakes; mentoring gives me the chance to share those lessons and show entrepreneurs the shortcuts I wish I’d known earlier," Ethier says. "At Energytech Nexus, that role goes beyond just helping individual founders — it’s about creating a flywheel effect for Houston’s entire innovation ecosystem."

Jeremy Pitts, Activate Houston

Jeremy Pitts serves as managing director of Activate Houston, which launched in Houston last year. He was one of the founders of Greentown Labs in the Boston area and served in a leadership role for the organization between 2011 and 2015. Through Activate, he has mentored numerous impactful startups and Innovation Awards finalists, including Solidec, Coflux Purification, Bairitone Health, Newfound Materials, Deep Anchor Solutions and others.

"Being a mentor to me is very much about supporting the person in whatever they need. Oftentimes that means supporting the business—providing guidance and advice, feedback, introductions, etc," But just as important is recognizing the person and helping them with whatever challenges they are going through ... Sometimes they need a hype man to tell them how awesome they are and that they can go do whatever hard thing they need to do. Sometimes they just need an empathetic listener who can relate to how hard these things are. Being there for the person and supporting them on their journey is key to my mentorship style."

Joe Alapat, Liongard

Joe Alapat founded and serves as chief strategy officer at Houston software company Liongard and chief information officer at Empact IT, which he also owns. He mentors through Founder Fridays Houston Group, Software Day by Mercury Fund, SUPERGirls SHINE Foundation, Cup of Joey and at the Ion. He's worked with founders of FlowCare, STEAM OnDemand, Lokum and many other early stage startups.

"Being a mentor to me means unleashing an individual’s 10x—their purpose, their ikigai (a Japanese concept that speaks to a person’s reason for being)," Alapat says. "Mentoring founders in the Houston community of early stage, high-growth startups is an honor for me. I get to live vicariously through a founder’s vision of the future. Once they show me that compelling vision, I’m drawn to bring the future forward with them so the vision becomes reality with a sense of urgency."

Neal Dikeman, Energy Transition Ventures

Neal Dikeman serves as partner at early stage venture fund Energy Transition Ventures, executive in residence at Greentown Labs, and offices in and supports Rice Nexus at the Ion. He mentors startups, like Geokiln, personally. He also mentored Helix Earth through Greentown Labs. The company went on to win in the Smart Cities, Transportation & Sustainability contest at SXSW earlier this year. Dikeman has helped launch several successful startups himself, most recently serving on the board of directors for Resilient Power Systems, which was acquired by Eaton Corp for $150 million.

"Founders have to find their own path, and most founders need a safe space where they can discuss hard truths outside of being 'on' in sales mode with their team or board or investors, to let them be able to work on their business, not just in it," Dikeman says.

Nisha Desai, Intention

Nisha Desai serves as CEO of investment firm Intention and mentors through Greentown Labs, TEX-E, Open Minds, the Rice Alliance Clean Energy Accelerator, Avatar Innovations and The Greenhouse. She currently works with founders from Solidec, Deep Anchor Solutions, CLS Wind and several other local startups, several of which have been nominated for Innovation Awards this year. She's served a board member for Greentown Labs since 2021.

"When I first started mentoring, I viewed my role as someone who was supposed to prevent the founder from making bad decisions. Now, I see my role as a mentor as enabling the founder to develop their own decision-making capability," Desai says. "Sometimes that means giving them the space to make decisions that might be good, that might be bad, but that they can be accountable for. At the end of the day, being a mentor is like being granted a place on the founder's leadership development journey, and it's a privilege I'm grateful for."

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The Houston Innovation Awards program is sponsored by Houston City College Northwest, Houston Powder Coaters, FLIGHT by Yuengling, and more to be announced soon. For sponsorship opportunities, please contact sales@innovationmap.com.

Rice, Houston Methodist developing soft 'sleep cap' for brain health research

Researchers and scientists at Rice University and Houston Methodist are developing a “sleep cap” that aims to protect the brain against dementia and other similar diseases by measuring and improving deep sleep.

The project is a collaboration between Rice University engineering professors Daniel Preston, Vanessa Sanchez and Behnaam Aazhang; and Houston Methodist neurologist Dr. Timea Hodics and Dr. Gavin Britz, director of the Houston Methodist Neurological Institute and chairman of the Department of Neurosurgery.

According to Rice, deep sleep is essential for clearing waste products from the brain and nightly “cleaning cycles” help remove toxic proteins. These toxic proteins, like amyloids, can accumulate during the day and are linked to Alzheimer’s disease and other neurological issues.

Aazhang, director of the Rice Neuroengineering Initiative, and his team are building a system that not only tracks the brain’s clearing process but can also stimulate it, improving natural mechanisms that protect against neurodegeneration.

Earlier proof-of-concept versions of the caps successfully demonstrated the promise of this approach; however, they were rigid and uncomfortable for sleep.

Preston and Sanchez will work to transform the design of the cap into a soft, lightweight, textile-based version to make sleep easier, while also allowing the caps to be customizable and tailored for each patient.

“One of the areas of expertise we have here at Rice is designing wearable devices from soft and flexible materials,” Preston, an assistant professor of mechanical engineering, said in a news release. “We’ve already shown this concept works in rigid device prototypes. Now we’re building a soft, breathable cap that people can comfortably wear while they sleep.”

Additionally, the research team is pursuing ways to adapt their technology to measure neuroinflammation and stimulate the brain’s natural plasticity. Neuroinflammation, or swelling in the brain, can be caused by injury, stroke, disease or lifestyle factors and is increasingly recognized as a driver of neurodegeneration, according to Rice.

“Our brain has an incredible ability to rewire itself,” Aazhang added in the release. “If we can harness that through technology, we can open new doors for treating not just dementia but also traumatic brain injury, stroke, Parkinson’s disease and more.”

The project represents Rice’s broader commitment to brain health research and its support for the Dementia Prevention Research Institute of Texas (DPRIT), which passed voter approval last week. The university also recently launched its Rice Brain Institute.

As part of the project, Houston Methodist will provide access to clinicians and patients for early trials, which include studies on patients who have suffered traumatic brain injury and stroke.

“We have entered an era in neuroscience that will result in transformational cures in diseases of the brain and spinal cord,” Britz said in the release. “DPRIT could make Texas the hub of these discoveries.”
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