This week's Houston innovators to know are hoping to make an impact. Courtesy photos

Starting off a new — hopefully drier — week in Houston, these three Houston innovators to know are looking to make an impact. From using tech for good to creating a women's movement in Texas business, these three Houstonians are on a roll.

Cristen Reat, co-founder and program director at BridgingApps

BridgingApps, a program backed by Easter Seals of Greater Houston, uses technology like iPads to help provide services for children and adults with disabilities — as well as for veterans — and their families. Courtesy of BridgingApps

At the cusp of the tablet generation, Cristen Reat saw her child, who had down syndrome, and this convenient emerging technology and connected the dots. She helped start a support group in a therapy clinic where many parents were interested about why mobile devices and apps were so engaging to their children.

"We were just amazed about how our children with different types of disabilities were engaged with the devices, were able to communicate with the devices, and were making big strides in their therapy," says Reat.

BridgingApps was founded by Reat and Sami Rahman in 2010, both seeking to help their children grow. The program became a part of Easter Seals of Greater Houston in 2011. The website currently boasts over 3,000 apps which users can sort through by category, age, price, skill, grade level, mobile device, and more. The apps are also able to benefit and treat veterans and their families. Read more about Reat and the BridgingApps program here.

Charley Donaldson, co-founder and COO of CaringBand

CaringBand is using a simple technology to better connect family and friends to the ones they love. Courtesy of CaringBand

When Charley Donaldson's mother-in-law was diagnosed with cancer, he and his wife knew they were in for a tough time. What they didn't realize was how important communication was going to be with each other. The ability to check in with loved ones frequently is tough — whether it's a good day or a bad day, people are busy and picking up the phone can be time consuming.

"It's like, you want to show people that you care about them, but you don't want to interrupt their day, or you don't want to be a burden to them if they aren't up to company," Donaldson says.

CaringBand is a light-up bracelet that's Bluetooth enabled, and connects to a mobile app. A person gives the bracelet to a loved one, who then pairs it with his or her smartphone. App users can send and receive pre-set messages of encouragement to and from other app users. Those wearing a CaringBand bracelet get alerted by a blinking light or vibration that lets them know someone is thinking about them. The wearer then reads these encouraging messages on the CaringBand app when convenient and with no need to respond. Read more about the Houston company connecting loved ones.

Ludmila Golovine, president and CEO of MasterWord Services Inc. and a founding member of Women in Localization's Texas Chapter

Ludmila Golovine, president and CEO of MasterWord Services Inc. and a founding member of newly formed Women in Localization's Texas Chapter, writes on the importance of localization. Courtesy of Golovine

Your business message is only as good as the receiver's ability to understand it. Localization is extremely important for business growth, and Ludmila Golovine, president and CEO of MasterWord Services Inc., wrote a guest article for InnovationMap about this importance as it pertains to the digital age.

"Opening a website or an app that wasn't intended for you can feel a lot like being lost in another country: you cannot understand the street signs, everything is different, and you don't even know how to ask a question of where to go," she writes.

Golovine is a founding member of newly formed Women in Localization's Texas Chapter. The organization is hosting its first Houston panel and networking event on Tuesday, September 24, from 6 to 8 p.m. at Station Houston. Read Golovine's guest article here.

CaringBand is using a simple technology to better connect family and friends to the ones they love. Courtesy of CaringBand

Houston startup creates device to keep loved ones in touch with each other

Caring is sharing

When Charley Donaldson's mother-in-law was battling cancer, he and his wife had great support from their friends and family. But they also knew there were a lot of people who cared about them who didn't know what to say or do during such a challenging time.

"It's like, you want to show people that you care about them, but you don't want to interrupt their day, or you don't want to be a burden to them if they aren't up to company," Donaldson says about the common reactions he heard from others – and often felt himself when he had friends going through similar struggles. "There had to be a way to share the idea of, 'Hey, I'm thinking about you.'"

It took three years of rattling around that idea before CaringBand came to life. The light-up bracelet is Bluetooth enabled, and connects to a mobile app. A person gives the bracelet to a loved one, who then pairs it with his or her smartphone. App users can send and receive pre-set messages of encouragement to and from other app users.

Those wearing a CaringBand bracelet get alerted by a blinking light or vibration that lets them know someone is thinking about them. The wearer then reads these encouraging messages on the CaringBand app when convenient and with no need to respond.

"When we pilot tested it, we were super excited to find out what we thought was validated," says Donaldson. "People really loved knowing that others were keeping them in their thoughts, and those who sent messages liked that they didn't have to worry about saying or doing the wrong thing."

Donaldson says he wanted The CaringBand to be as easy as possible for people to use, and also ensure that it was a solid support system. When someone is going through medical treatments, he knows that can be exhausting, and he also realizes that friends and family want to be able to do something, anything, to express their love and support.

"If you're a normal, compassionate person, you want to show you care about someone," he says. "This lets you do that in your own way."

And while it might sound like The CaringBand is designed to make the senders of messages feel better about offering a good thought for someone, Donaldson says those going through treatments have really loved seeing their bracelets light to up to tell them they're on someone's mind. That small show of support has made a big difference, they told Donaldson in surveys.

"She is sitting on the couch having so much fun reading her messages," says one user in a testimonial. "The smile on her face is priceless." "People tell you they think of you and pray for you all the time," read another. "The bracelet gives you a reminder that they really are."

"We made it super easy," he says. "It's a hardware to software solution and we wanted to erase as many friction points as possible in its creation. This is two touches of a smart phone."

Currently, the CaringBand app is live and functional. The bracelet is still in developmental stages, and Donaldson says the team is working with individuals and groups such as the Tyler Robinson Foundation to further test it. The bracelet should be a go for full distribution and sale by the first quarter of 2020.

"Obviously, this doesn't replace driving over to see someone or having a cup of coffee with a friend," says Donaldson. "But it is a great supplemental tool to show your love and care when you might not know what else to do."

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”