Houston-based Complete Intelligence was just recognized by Capital Factory as the "Newcomer of the Year." Photo via completeintel.com

The business applications of artificial intelligence are boundless. Tony Nash realized AI's potential in an underserved niche.

His startup, Complete Intelligence, uses AI to focus on decision support, which looks at the data and behavior of costs and prices within a global ecosystem in a global environment to help top-tier companies make better business decisions.

"The problem that were solving is companies don't predict their costs and revenues very well," says Nash, the CEO and founder of Complete Intelligence. "There are really high error rates in company costs and revenue forecasts and so what we've done is built a globally integrated artificial intelligence platform that can help people predict their costs and their revenues with a very low error rate."

Founded in 2015, Complete Intelligence is an AI platform that forecasts assets and allows evaluation of currencies, commodities, equity indices and economics. The Woodlands-based company also does advanced procurement and revenue for corporate clients.

"We've spent a couple years building this," says Nash. "We have a platform that is helping clients with planning, finance, procurement and sales and a host of other things. We are forecasting equity markets; we are forecasting commodity prices, currencies, economics and trades. We built a model of the global economy and transactions across the global economy, so it's a very large, very detailed artificial intelligence platform."

That platform, CI Futures, has streamlined comprehensive price forecasting and data analysis, allowing for sound, data-based decisions.

"Our products are pretty simple," says Nash. "We have our basic off the shelf forecast which is called CI Futures, which is currencies, commodities, equities and economics and trade. Its basic raw data forecasts. We distribute that raw data on our website and other data distribution websites. We also have a product called Cost Flow, which is our procurement forecasting engine, where we build a material level forecasting for clients.


completeintel.com

"Then we have a product that we'll launch next year called Revenue Flow, which is a sales forecasting tool that will use balance of both client data and publicly available data to forecast client sales by product, by geography and so on and so forth. So we really only do three things: revenues, costs and raw data forecasts."

Forecasting across industries

Complete Intelligence's Cost Flow and Revenue Flow products are specific to direct clients. They are working with clients in the food and beverage sector, the energy sector, the chemical sector, and the technology sector.

"Anybody that manufactures a tangible good, should use our product," says Nash. "Because we can take their historical data we can configure their bills of material and they can see the exact cost and exact revenue of those products by month over time."

CI is not a consulting firm, so they offer their clients an annual license, which allows them to receive updated forecasts every month to understand how markets will iterate over time.

"We're integrating with the client's enterprise data," says Nash. "Whether it's their ERP system or their procurement system or their CRM, we're integrating with client's enterprise data, and we're creating forecast outlooks that are perfectly contextually relevant for client buying decisions."

Called out by Capital Factory

As a business solution, CI has garnered widespread industry confidence and accolades, such as Capital Factory's coveted "Newcomer of the Year" award, which recognizes innovative companies from a pool of 110 startups in Texas.

"Honestly, I couldn't believe it because with a startup like ours, there's so much hard work that goes into it, there's so much time, there's so much persistence," says Nash.

"And the types of startups that Capital Factory attracts are very competitive startups, so for us to receive this award, it's given us a huge amount of credibility in the market and it's really encouraged the team inside the company to understand that what we're doing is being recognized, it's meaningful and we're really going places."

From consulting to billions of monthly calculations

Nash is no stranger to going places. Before setting up shop in his native Texas, he lived in Singapore for 15 years where he started his career in sourcing and procurement for American retail firms.

"I became very sensitive to costs, cost inflections and I got very involved in global sourcing and international trade and then I did a couple of corporate turnarounds and start ups and so with that you see costs as an issue with those types of firms," Nash says.

He then worked with the Economist running their global research business. There, he grew familiar with how clients and customers use data. At IHS Markit, a global information provider.

"When I was working with those firms, those firms helped companies with planning," says Nash. "The problem is that those firms have very large errors in their forecasts. It is not just the internal forecasts that have a 30 percent or higher error rate in their forecasts, even the industry forecasters typically have around a 20 percent error rates in their forecasts.

"Even the people who should actually know where prices are going are not very good forecasters. With Complete Intelligence, we wanted to use data and use artificial intelligence to machine learning to create a better way to identify where costs and revenues will go for companies."

Every month, CI runs billions of calculations. They test their error rates and record them for clients that request them. With 700 assets that they show publicly, CI their average error rate is 3.7 percent, which is dramatically lower than both corporate procurement professionals and industry experts.

"With us doing billions of calculations, it allows us to run simulations and scenarios that your average analyst just can't do and most companies haven't even thought of. We're able to run a comprehensive view of activities in the world to understand how things directly and indirectly affect a cost. In Houston, for example, that could be crude oil or natural gas or something like that."

Proving its value

Last year, the company tested its platform with a natural gas trader. After reviewing the data, CI revealed to the client that natural gas would fall by 40 percent over the next year.

"They looked at our forecast and said they couldn't work with us because it didn't make sense," says Nash. "A 40 percent fall didn't make sense, so they didn't subscribe to us. That was 2018. What has happened over the past 12 months? Natural gas prices had fallen by 49 percent. You would look at our forecasts and say, 'Wow, that's a dramatic drop over 12 months.' But reality was even more dramatic than that and there weren't analysts out there saying what our model was telling us."

That natural gas trading company never admitted its faux pas, but if they had listened to CI, they could have positioned themselves to negotiate their vendors down for their cost base, which helps the margin of their business.

"Nobody ever admits mistakes," says Nash. "But when you think about the numerous materials that require natural gas, especially things that are manufactured in Houston, it affects a lot of costs."

Houston roots — by way of Asia

The missed opportunity with the natural gas trader notwithstanding, Nash is happy that he brought Complete Intelligence to Houston.

"I went to Texas A&M and grew up in Texas, so I moved back to Texas knowing how good Americans are with planning, with math and with data. I like Houston because people make stuff in Houston," Nash says. "We just found Houston to be perfect after spending 15 years in Asia given the global centrality of Houston. The industry's here and there's a lot of diversity in Houston."

Nash's expectation was that he would be able to work with Western multinationals to improve their analytics and their artificial intelligence processes because he has learned that there is a lot of pressure in American financial markets and analysts communities to really know what is happening within companies.

"We want companies to be able to really tightly plan their costs so they can better improve their profitability," says Nash. "That's what I wanted to do when we moved to the U.S. and we're finding that there's a lot of interest from companies."

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Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.

Elon Musk's SpaceX site officially becomes the city of Starbase, Texas

Starbase, Texas

The South Texas home of Elon Musk’s SpaceX rocket company is now an official city with a galactic name: Starbase.

A vote Saturday, May 3, to formally organize Starbase as a city was approved by a lopsided margin among the small group of voters who live there and are mostly Musk’s employees at SpaceX. With all the votes in, the tally was 212 in favor to 6 against, according to results published online by the Cameron County Elections Department.

Musk celebrated in a post on his social platform, X, saying it is “now a real city!”

Starbase is the facility and launch site for the SpaceX rocket program that is under contract with the Department of Defense and NASA that hopes to send astronauts back to the moon and someday to Mars.

Musk first floated the idea of Starbase in 2021 and approval of the new city was all but certain. Of the 283 eligible voters in the area, most are believed to be Starbase workers.

The election victory was personal for Musk. The billionaire’s popularity has diminished since he became the chain-saw-wielding public face of President Donald Trump’s federal job and spending cuts, and profits at his Tesla car company have plummeted.

SpaceX has generally drawn widespread support from local officials for its jobs and investment in the area.

But the creation of an official company town has also drawn critics who worry it will expand Musk’s personal control over the area, with potential authority to close a popular beach and state park for launches.

Companion efforts to the city vote include bills in the state Legislature to shift that authority from the county to the new town’s mayor and city council.

All these measures come as SpaceX is asking federal authorities for permission to increase the number of South Texas launches from five to 25 a year.

The city at the southern tip of Texas near the Mexico border is only about 1.5 square miles (3.9 square kilometers), crisscrossed by a few roads and dappled with airstream trailers and modest midcentury homes.

SpaceX officials have said little about exactly why they want a company town and did not respond to emailed requests for comment.

“We need the ability to grow Starbase as a community,” Starbase General Manager Kathryn Lueders wrote to local officials in 2024 with the request to get the city issue on the ballot.

The letter said the company already manages roads and utilities, as well as “the provisions of schooling and medical care” for those living on the property.

SpaceX officials have told lawmakers that granting the city authority to close the beach would streamline launch operations. SpaceX rocket launches and engine tests, and even just moving certain equipment around the launch base, requires the closure of a local highway and access to Boca Chica State Park and Boca Chica Beach.

Critics say beach closure authority should stay with the county government, which represents a broader population that uses the beach and park. Cameron County Judge Eddie Trevino, Jr. has said the county has worked well with SpaceX and there is no need for change.

Another proposed bill would make it a Class B misdemeanor with up to 180 days in jail if someone doesn’t comply with an order to evacuate the beach.

The South Texas Environmental Justice Network, which has organized protests against the city vote and the beach access issue, held another demonstration Saturday that attracted dozens of people.

Josette Hinojosa, whose young daughter was building a sandcastle nearby, said she was taking part to try to ensure continued access to a beach her family has enjoyed for generations.

With SpaceX, Hinojosa said, “Some days it’s closed, and some days you get turned away."

Organizer Christopher Basaldú, a member of the Carrizo/Comecrudo Nation of Texas tribe, said his ancestors have long been in the area, where the Rio Grande meets the Gulf.

“It’s not just important,” he said, “it’s sacred.”