The Business Angel Minority Association launched at a breakfast event during Houston Tech Rodeo. Photo by Nijalon Dunn

Maria Maso was frustrated with her investment opportunities in Houston. So, she's doing something about it.

Maso has launched the Business Angel Minority Association, or baMa, to gather established or brand new angel investors to move the needle on investments into minority-founded startups. The organization, which launched at a breakfast event at Amegy Bank's Cannon Tower during the Houston Tech Rodeo week, is now seeking investor members.

A native of Barcelona, Maso moved to Houston around seven years ago and started investing in startups a few years later. She tapped into a local organization, but didn't have a positive experience.

"I joined an organization in town, and I started to see deals. But I never made an investment in those deals. I faced two issues: They weren't inclusive enough and no one was telling me how to invest," Maso says.

She joined other angel groups around the world, wrote a lot of checks, and still was frustrated with what was available in Houston. She reached a breaking point in October and her friend and colleague, Juliana Garaizar, told her, "If you don't like it, change it."

So, baMa was born and has launched with lofty goals. Maso, founder and CEO, and Garaizar, president, want to round up 100 investors by the end of 2020. And they want these investors to write checks.

"We are not a networking organization. We are an investment organization. We are expecting at some point that you are writing a check to a startup," Maso tells the crowd. "If we are doing our job properly and we are showing you the right startups, you should be able to make a check at some point."

The organization's members will see deal flow and regular pitches and programming. At the launch event, three Houston companies — Kanthaka, on-demand personal training app, Security Gate, cybersecurity startup, and Pantheon, wellness program app — pitched to the room.

"This is a great opportunity — this is not impact investing or doing the right thing," Garaizar says. "This is actually going to generate money. Investing in diversity gives a 35 percent more ROI to investors."

BaMa already has plans to grow, Maso says. The organization will have a national presence with multiple chapters across the country.

"We are already discussing with Boston, Miami, and Palo Alto," says Maso. "We don't have an agreement yet, but my plan is by the end of the year open the second chapter."

But starting in Houston was intentional. There's so much untapped potential in Houston — money wise and in terms of startups.

"We are in Houston, the most diverse city in the U.S., and still our investment community doesn't look like our entrepreneurship community," Garaizar says. "The only way we are going to bridge this gap is if our investment community starts looking more like the entrepreneurship community."

For Carolyn Rodz, founder of Houston-based Alice and baMa partner, she's tired of hearing about the lack of minority investors and diversity of investments. This organization is about making a move.

"We've had enough talk with all these issues — how do we actually take the actions to move this forward," Rodz says. "I'm tired of hearing the same story year after year, and every time I hear the statistics, I roll my eyes. We know the story. We've heard it. Let's actually do something to change it."

Houston is hosting a bit of a tech takeover week during the first week of March. Photo by Zview/Getty Images

These are the events to attend each day during the Houston Tech Rodeo

Where to be

Houston Exponential has tapped into the Houston innovation ecosystem to coordinate a week of events to speak to the city's startups, investors, and startup development organizations.

The week, called the Houston Tech Rodeo, will take place March 2 to 6 — in coordination with the start of the Houston Livestock Show And Rodeo — all across town. From panels and meetups to office hours and pitch events, there's a lot to navigate in the inaugural week. For a complete list of Tech Rodeo events (most of which are free and all over town), head to the website.

Here are the events you should make sure not to miss. Each featured event is free and open to the public.

Monday: Houston Tech Rodeo Kickoff Event

Launching the week is a happy hour event with a networking opportunity and a panel brought to you by InnovationMap, KPMG, and Houston Exponential. The event is on Monday, March 2, from 4 to 6:30 pm at Karbach Brewing Co. (2032 Karbach St.). After a short introduction from KPMG and HX, Blair Garrou, managing director at Mercury Fund; Leslie Goldman, general partner at The Artemis Fund; and Samantha Lewis, director of GOOSE, will discuss the VC culture in Houston vs. the world. Click here to register.

Tuesday: The Founders Round Up at The Cannon

Why attend one event when you can attend a day full of constructive events geared at entrepreneurs? From 9 am to 5 pm on Tuesday, March 3, at The Cannon, catch workshops and panels ranging from startup failure reasons to revenue tips. From 3 to 5 pm, there's a lean startup meet-up workshop to attend. Click here to register.

Additional events:

  • HX will also be hosting its "Conventional Financing for your Tech Business" workshop at 9 am at their office (410 Pierce St.) to help startups navigate their financial options. Click here to register.
  • DivInc. will be hosting an evening event to address "Diversity's Impact on Innovation" at The Ion (1301 Fannin St. Suite 2100). This event runs from 5:30 to 9 pm. Click here to register.

Wednesday: Jason Calacanis Founder Office Hours

Seven Houston entrepreneurs will join investor Jason Calacanis onstage for office hours — but with an audience. The event, which is on Wednesday, March 4, from 9:30 to 11 am with networking to follow, is at Rice University - McNair Hall McNair Hall, Loop Road Shell Auditorium. Click here to register.

Additional event: The University of Houston's Office of Research is hosting a "Women in Science and Beyond" panel of successful female scientists. The event will take place at 5 pm at UH Technology Bridge Innovation Center, Building 4 (5000 Gulf Freeway). Click here to register.

Thursday: Reverse Pitch, Accelerators and Funds with the Ask

The tables have turned. Rather than Houston entrepreneurs pitching, accelerators and startup development organizations are taking the stage to pitch their programs to potential startup members. The event, which is at 9 am at Sesh Coworking (1210 West Clay St. #Suite 18) on Thursday, March 5, will be hosted by Brittany Barreto of Capital Factory. Click here to register.

Additional events:

  • Learn from the leading ladies of Houston innovation in The Ion's EmpowerHER event at 11 am at 1301 Fannin St. Suite 2100. Click here to register.
  • Wrap up your day with a networking opportunity from MassChallenge Texas at the C. Baldwin, Curio Collection by Hilton (400 Dallas Street). Click here to register.

Friday: BAMA Houston Launch Event

Celebrate the launch of the Business Angel Minority Association — a new organization looking to increase investments for minority-run startups. The networking and pitch event is on Friday, March 6, from 8 to 10 am at The Cannon Tower - Amegy Conference Center (1810 Main St, Suite 1300). Click here to register.

Additional event: Wrap up your week with networking hosted by HX. The event is from 5 to 7 pm at Saint Arnold Brewing Company (2000 Lyons Ave.) Click here to register.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."