One of the winning teams at Climathon has an idea for a microgrid system in Houston's emerging innovation corridor. Photo via houston.org

More than 6,000 participants in 145 cities around the world gathered virtually for last year's Climathon, a global event put on by Impact Hub Houston to unite innovators and collaborate on climate solutions. When Winter Storm Uri left the Texas energy grid in a state of crisis, one Climathon Houston team's proposal for energy reliability became all the more important.

Last year, the City of Houston unveiled its first Climate Action Plan to address the city's challenges and strive to lead the energy transition. It was the perfect roadmap for Climathon Houston, a hackathon where eleven teams gathered to develop and pitch a concept to align with the city's new plan.

Of the three winning teams, one idea was prescient in its approach to energy. Six energy-focused Texans drew up plans for InnoGrid, a cost-effective strategy to build the first microgrid in Houston. What started as a pitch has become a developed proposal gaining collaborator and city interest in the wake of Uri.

Bryan Gottfried, Edward D. Pettitt II, Andi Littlejohn, Paresh Patel, Ben Jawdat, and Gavin Dillingham created InnoGrid to to help achieve the CAP's energy transition and net-zero emissions goals. With climate events increasing rapidly, the team of innovators saw an opportunity to create a sustainable solution — the first Houston microgrid.

In just an hour and a half of brainstorming, the team sought to create a similar model to Austin's Whisper Valley microgrid — a project that's currently in development. While Whisper Valley is a master plan community, the team wanted to create a microgrid to support a larger picture: the city of Houston.

"I had been following transactive energy models [such as] peer-to-peer electricity trading like Brooklyn Microgrid/LO3 Energy and Power Ledger since their inception. This inspired my vision for a novel microgrid that would demonstrate such technologies in the energy capital of the world that is otherwise primarily focused on oil and gas, and natural resources," explains Patel, founder and CEO of e^2: Equitable Energy.

When Pettitt joined the group, he proposed the growing Houston Innovation Corridor as the home to InnoGrid. The four-mile stretch between the Texas Medical Center and Downtown is already home to green technology, making it an ideal fit.

"You're going into an area that was already being redeveloped and had this innovation kind of mentality already," explains Gottfried, a geoscientist and current MBA student at University of Houston Bauer College of Business.

After winning Climathon Houston, the team continued to meet weekly in hopes of making InnoGrid a reality.

The case for a microgrid

The InnoGrid team started with the goal of making energy reliable and resilient in the face of climate change. While previous storms like Hurricane Ike have left millions of Texans without power, Winter Storm Uri was one of the most destructive tragedies to face Texas. The unexpected February storm left 4.5 million Texans without electricity and resulted in at least 111 deaths.

As InnoGrid's team members struggled with burst pipes and loss of power, the team juggled the task of submitting a grant application to the Department of Energy during a catastrophic winter storm. The timing was not lost on them.

"It underscored the need for us to do something like this," shares Gottfried.

To understand how impactful a Houston microgrid can be, you first must understand how a microgrid works. A microgrid is a local energy grid made of a network of generators combined with energy storage. The microgrid has control capability, meaning it can disconnect from a macro grid and run autonomously.

Ultimately, microgrids can provide reliability and drive down carbon emissions. Using smart meters, the grids can even provide real-time energy data to show the inflow and outflow of electricity. In the instance a microgrid does go down, it only affects the community — not the entire state. Likewise, during a power outage to the main grid, a microgrid can break away and run on its own.

Microgrids have been deployed by other cities to mitigate the physical and economic risks caused by power outages, but the use of a project like InnoGrid feels especially timely given recent events and the limitations of the Texas Interconnect.

The Texas grid is isolated by choice, separated from the eastern and western interconnects. Texas' isolated energy grid resulted in a massive failure, proving deregulation can certainly backfire. Updating the electric grid has an expensive price tag, but microgrids show a promising and cost-effective model for the future.

"I thought if microgrids and mini-grids are enabling millions in off-grid frontier markets at the base of the pyramid [like Asia, Sub-Saharan Africa, etc.] to essentially leapfrog legacy energy infrastructure, why should we not upgrade our aging power system with the latest tech that is digitalized, decarbonized, decentralized/distributed, and democratized at the top of the pyramid," asks Patel.

Many hospitals, universities, and large technology firms have already established their own microgrids to protect equipment and provide safety. Still, smaller businesses and homes in the community can suffer during outages.

InnoGrid's proposal seeks to use existing and proven renewable energy sources like wind, solar and geothermal energy. The storage technologies used would include battery, kinetic, compressed air, and geomechanical pumped storage.

"From the perspective of an early-stage hardware startup, one of the most important things is finding a way to validate and test your technology," explains Jawdat, founder and CEO of Revterra and adviser to the InnoGrid team. He explains that the microgrid "can also be a testbed for new technologies, specifically, new energy storage technologies," through potential partnerships with companies like Greentown Labs, which is opening its Houston location soon.

Battling inequity 

While the outlook for a community microgrid is enticing, there are also challenges to address. One key challenge is inequity, which is a key focus of Pettitt who was drawn to the team's goal of providing stability for companies and residences in Houston.

Pettitt, who is seeking a Ph.D. in urban planning and environmental policy at Texas Southern University, has a background in public health and frequently works with the Houston Coalition for Equitable Development without Displacement. "I'm really looking at the intersection of the built environment and how to make cities healthier for its residents," he shares.

"A lot of companies are trying to prevent this climate crisis where we have climate refugees that can't live in certain areas because of ecological damage. But in the process, we don't want to create economic refugees from the gentrification of bringing all of these companies and higher-wage jobs into an area without providing folks the ability to benefit from those jobs and the positive externalities of that development," explains Pettitt.

The InnoGrid would plan to provide positive externalities in the form of energy subsidies and potentially even job training for people who want to work on the grid.

Power to the consumer

Much like the gamification in feel-good fitness trackers and e-learning tools, reward systems can inspire friendly competition and community engagement. InnoGrid's proposal seeks to challenge other major cities to build their own grids and compete with a gamified system.

The Innovation Corridor is currently undergoing major redevelopment, the first 16 acres of which are being developed by Rice Management Company and will be anchored by The Ion, which is opening soon. The timing of this redevelopment would allow a prospective project like InnoGrid to build in visual and interactive aspects that depict energy usage and carbon offsetting.

The microgrid's statistics would also engage Houstonians by sharing up-to-date data through dashboards, apps, and even billboards to track Houston's carbon footprint. Pettitt paints a picture of interactive sidewalk structures, leaderboards, and digital billboards in the public realm to showcase how energy is used day-to-day. The team hopes to build positive feedback cycles that encourage tenants and building owners to be more energy-efficient.

"If we're having an Innovation Corridor, an innovation district, I think the built environment should be innovative too," explains Pettitt.

The future of InnoGrid

Every innovation has to start somewhere. While InnoGrid is in its early stages, the team is working to establish partners and collaborators to make the project a reality.

Inspired by projects like the Brooklyn Microgrid, InnoGrid is in the process of pursuing partnerships with utilities and energy retailers to form a dynamic energy marketplace that pools local distributed energy resources. The team hopes to collaborate with microgrid experts from around the nation like Schneider Electric and SunPower. Other potential collaborators include The Ion, CenterPoint, Greentown Labs, and Rice Management Company.

Can Houston remain the energy capital of the world as it transitions to a net-zero energy future? The InnoGrid team wants to make that happen. The argument for a microgrid in Houston feels even more fitting when you look at the landscape.

"If we are going to create an innovative microgrid that also functions as a testbed for innovators and startups, [we] have proximity to some of the biggest utilities and power generation players right in that sector," explains Patel, who is also an inaugural member of Greentown Labs Houston.

"The microgrid itself is not novel. I think what makes it compelling is to situate that right here in the heart of the energy capital as we, again, reincarnate as the energy transition capital world," Patel continues.

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Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”

10+ Houston innovation leaders in the spotlight at SXSW 2026

where to be

Houston's innovation scene will be well represented at South by Southwest (SXSW) this month.

The week-long, Austin-based conference and festival will spotlight some of the Bayou City's leaders in health care, energy, space and more. The event kicks off today, March 12, and runs through March 18. The SXSW Innovation Conference will feature keynotes, workshops, mentoring sessions and more throughout various venues in the city.

Here's who to see and when and where to find them:

March 12

Aileen Allen, venture partner at Mercury Fund

Mentor Session from 4-5:15 p.m. at Hilton Austin Downtown

Allen will host a mentoring session focused on funding, marketing, advertising, PR and the future of work.

March 13

Heath Butler, partner at Mercury Fund

SXSW Pitch-Smart Cities, Transportation, Manufacturing & Logistics from 2:30-3:30 p.m. at the J.W. Marriott

Butler will judge five innovative startups as they pitch their solutions to advance smart cities, enhance transportation systems, modernize manufacturing, transform logistics, and strengthen government infrastructure and civic operations.

Jonathan Cirtain, CEO and president of Axiom Space

The Clock is Ticking for Space - Replacing the ISS from 4-5 p.m. at the J.W. Marriott

Cirtain will discuss Axiom's pursuit of building the world’s first commercial space station.

March 14

Jesse Martinez, founder and CEO of LSA Global

SXSW Pitch-Intelligent Systems, Robotics, & Multisensory Technology from 10-11 a.m. at the J.W. Marriott

Martinez will judge five innovative startups as they pitch their technologies that aim to enhance the way people connect, communicate and share unique life experiences with those around them in a digital ecosystem.

Jennifer Schmitt, head of operations at Rhythm Energy

Powering Texas with Reliable Integrated High-Demand Energy from 10-11 a.m. at Marlow

Schmitt will join a panel to discuss how EirGrid, the state-owned electric power transmission operator in Ireland, is pioneering solutions as the country works toward 80 percent renewable integration by 2030.

Saki Sasagawa, director of business development for JETRO Houston

Now is Japan's Time: Leading the Future with Deep Tech from 10-11 a.m. at the J.W. Marriott

Sasagawa joins a panel that will share real-time insights from diverse perspectives on the forefront of Japan’s deep tech and IP businesses.

March 15

Bosco Lai, CEO and co-founder of Little Place Labs

SXSW Pitch Alumni: Where Are They Now? from 10-11 a.m. at the J.W. Marriott

Lai joins a panel of four former SXSW Pitch winners to share how they leveraged the platform to take their startups to the next level.

Tara Karimi, cofounder and chief science and sustainability officer at Cemvita

South by South America: The Rise of Southern Brazil Tech from 2:30-3:30. p.m. at The Line

Karimi will participate in a panel to discuss how Rio Grande do Sul, Brazil's southernmost state, is attracting elite talent and AI infrastructure and share insights on navigating the next wave of South American tech growth.

March 16

Dr. Pavitra P. Krishnamani, emergency medicine physician at The University of Texas MD Anderson Cancer Center

Viva La Revolution: How the Digital Age is Transforming Wellness from 11:30 a.m.-12:30 p.m. at Hilton Austin Downtown

Krishnamani will discuss the latest advancements and policies that can accelerate the digital age of health care, such as wearables, telehealth and artificial intelligence.

March 18

Charlie Childs, co-founder and CEO of Intero Biosystems

Spinning Out: What It Takes to Build a University Startup from 2:30-3:30 p.m. at The Line

Childs will join founders who spun their companies out of the University of Michigan to share the real story of navigating IP, early capital, team building, market validation and the “valley of death.”

Dr. James Allison, regental chair of immunology and director of The Allison Institute at The University of Texas MD Anderson Cancer Center

Dr. Padmanee Sharma, professor in the Department of Genitourinary Medical Oncology, Division of Cancer Medicine at The University of Texas MD Anderson Cancer Center

Beyond Checkpoints: Immunotherapy’s Next Act from 2:30-3:30 p.m. at the J.W. Marriott

Allison and Sharma will sit down with 21-year-old, Stage 4 cancer survivor Sharon Belvin and Time Magazine journalist Alice Park will discuss the future of immunotherapy and what challenges remain.

Last year, Houston startups Little Places Labs and Helix Earth won top prizes in their respective categories at the prestigious SXSW Pitch event, held this year from March 13-14. No Houston startups were named finalists to compete in this year's event.

NASA revamps Artemis moon landing program by modeling it after Apollo

To the moon

NASA is revamping its Artemis moon exploration program to make it more like the fast-paced Apollo program half a century ago, adding an extra practice flight before attempting a high-risk lunar landing with a crew in two years.

The overhaul in the flight lineup came just days after NASA’s new moon rocket returned to its hangar for more repairs, and a safety panel warned the space agency to scale back its overly ambitious goals for humanity’s first lunar landing since 1972.

Artemis II, a lunar fly-around by four astronauts, is off until at least April because of rocket problems.

The follow-up mission, Artemis III, had been targeting a landing near the moon’s south pole by another pair of astronauts in about three years. But with long gaps between flights and concern growing over the readiness of a lunar lander and moonwalking suits, NASA’s new administrator Jared Isaacman announced that mission would instead focus on launching a lunar lander into orbit around Earth in 2027 for docking practice by astronauts flying in an Orion capsule.

The new plan calls for a moon landing — potentially even two moon landings — by astronauts in 2028.

“Everybody agrees. This is the only way forward,” Isaacman said.

The hydrogen fuel leaks and helium flow problems that struck the Space Launch System rocket on the pad at NASA's Kennedy Space Center in February also plagued the first Artemis test flight without a crew in 2022.

Another three-year gap was looming between Artemis II and the moon landing by astronauts as originally envisioned, Isaacman said.

Isaacman stressed that “it should be incredibly obvious” that three years between flights is unacceptable. He'd like to get it down to one year or even less.

Isaacman, a tech billionaire who bought his own trips to orbit and performed the world’s first private spacewalk, took the helm at NASA in December.

During NASA’s storied Apollo program, he said, astronauts’ first flight to the moon was followed by two more missions before Neil Armstrong and Buzz Aldrin landed on the moon. What's more, he added, the Apollo moonshots followed one another in quick succession, just as the earlier Projects Mercury and Gemini had rapid flight rates, sometimes coming just a few months apart.

Twenty-four Apollo astronauts flew to the moon from 1968 through 1972, with 12 of them landing.

“No one at NASA forgot their history books. They knew how to do this," Isaacman said. “Now we're putting it in action.”

To pick up the pace and reduce risk, NASA will standardize its Space Launch System rockets moving forward, Isaacman said. These are the massive rockets that will launch astronauts to the moon aboard Orion capsules. At the same time, Elon Musk's SpaceX and Jeff Bezos' Blue Origin are speeding up their work on the landers needed to get the astronauts from lunar orbit down to the surface.

Isaacman said next year will see an Orion crew rendezvousing in orbit around Earth with SpaceX's Starship, Blue Origin's Blue Moon or both landers. It's similar to the methodical approach that worked so well during Apollo in the late 1960s, he noted. Apollo 8, astronauts' first flight to the moon, was followed by two more missions before Armstrong and Aldrin aimed for the lunar surface.

“We should be getting back to basics and doing what we know works,” he said.

The Aerospace Safety Advisory Panel recommended that NASA revise its objectives for Artemis III “given the demanding mission goals.” It’s urgent the space agency do that, the panel said, if the United States hopes to safely return astronauts to the moon. Isaacman said the revised Artemis flight plan addresses the panel's concerns and is supported by industry and the Trump administration.