Houston's San Jacinto College is launching a biotechnology program in early 2024 to be housed in the Center for Biotechnology in Generation Park. Rendering courtesy of McCord

Houston's San Jacinto College will roll out a new biotechnology program in early 2024 as it gets closer to its goal of launching the Center for Biotechnology in Generation Park.

In partnership with the Ireland-based National Institute for Bioprocessing Research and Training, the licensed training curriculum will offer regional biopharmaceutical training at the college's South Campus starting in January.

Initially, the 90-hour hybrid training program will provide opportunities for participants to gain experience with "all aspects of biomanufacturing, specialized instrumentation and equipment training, and advanced techniques," according to a statement. Students will earn an onboarding certificate that will help them enter the field.

The college then plans to open the Center for Biotechnology, developed by McCord Development Inc., at its Generation Park Campus in the first quarter of 2025. The state-of-the-art facility is slated to allow for more hands-on training within simulated environments, and will allow students to earn associate of applied science degrees in biomanufacturing technology, as well as credentials for those already in the workforce.

“The biomanufacturing industry is seeing substantial growth in the Greater-Houston area,” Christopher Wild, executive director for the San Jacinto College Center for Biotechnology, says in a statement. “The College’s partnership to offer NIBRT’s premier, industry-leading training right here in the Houston-area represents a firm commitment to bolstering the biomanufacturing workforce pipeline which will help position the region for continued growth.”

The center will also offer programs that are customizable to industry partners' needs, according to a statement, and will provide cost-effective training for new hires. It will be the only NIBRT-licensed training in the Southwest and Southeast region.

“The NIBRT team have been very impressed by San Jacinto’s excellent track record in developing workforce programmes for the Greater Houston Region across a broad range of industrial sectors," Darrin Morrissey, CEO of NIBRT, says in a statement. We are very much looking forward to working with the San Jacinto team to deliver world class biopharma training programs to their students."

The new center is part of Generation Park, a 4,300-acre master-planned development in Northeast Houston. In late 2022, San Jac and McCord, which is developing Generation Park, shared that they had signed a memorandum of understanding with the NIBRT to launch the program and center.

At the time, San Jacinto College was slated to be the institute’s sixth global partner and second U.S. partner.

Over the summer, McCord also revealed plans for its 45-acre biomanufacturing campus at Generation Park.
Generation Park has announced additional biomanufacturing facility development. Rendering courtesy of McCord

Real estate company unveils plans for 45-acre biomanufacturing campus in Northeast Houston

life science upgrade

A Houston-based real estate company has reveals its plans to create a 45-acre biomanufacturing campus in the first phase of a life science development in Generation Park.

McCord Development released its plans for BioHub Two this week. The project will include 500,000 square feet for manufacturing, lab, and office space located in Generation Park, a 4,300-acre master-planned development in Northeast Houston.

The news of the BioHub follows Generation Park's December announcement of the San Jacinto College’s Biotech Training Center, a project in partnership with the National Institute of Biotechnology Research and Training. The institute will have a "bioprocessing pilot plant operated in a realistic GMP simulated and operational manufacturing environment," according to a news release from McCord.

“Houston has consistently been ranked as a burgeoning life science cluster, and BioHub Two has the unique advantage of being a short walk from the region’s only Biotech Training Center at San Jacinto College’s Generation Park campus," says John Flournoy, senior director of sales and leasing.

Last year, the Greater Houston Partnership released data showing the potential for the Bayou City as a hub for biomanufacturing, cell and gene therapy, cancer treatment, drug development, and more. Earlier this summer, Houston maintained its standing as a hub for life sciences on an annual report from CBRE.

“Houston’s high concentration of life sciences employment, healthy funding landscape, access to the Texas’ $6 billion CPRIT grant fund, and commitment to translational research is making it one of the country’s fastest growing life science ecosystems,” says Ryan McCord, president of McCord Development, in the release. “BioHub Two’s location in Generation Park is strategic and cost-effective, as the world-leading research and development facilities at the Texas Medical Center, Houston International Airport and Port of Houston are in close proximity.”

The larger Generation Part plans include two multifamily complexes, a mixed-use development called The Commons, and retail and green spaces.

The Texas Medical Center unveiled its plans for the TMC BioPort, a biomanufacturing and medical supplies distribution engine, almost a year ago. This new campus will span several hundred acres just down the road from TMC and will drive the much-needed repatriation of critical medical supplies and new cell and gene therapies, per a news release.

The opening of the pilot plant marks the debut of Cemvita’s eCO2 business as a wholly owned subsidiary. Photo courtesy of Cemvita

Fast-growing startup with carbon-free solution sets up pilot plant in Houston

big moves

Cleantech startup Cemvita has set up a pilot plant in its hometown of Houston to develop technology for converting carbon emissions as feedstock to make products like fertilizer, plastics, methane, and fuel.

The opening of the pilot plant marks the debut of Cemvita’s eCO2 business as a wholly owned subsidiary. The term eCO2 refers to equivalent carbon dioxide, or a way to measure a combination of greenhouse gases such as carbon dioxide and methane.

With a capacity of more than 14,000 gallons, the plant is producing eCO2 oil, an alternative to soybean oil. The company already is shipping samples of eCO2 products to customers, including renewable-fuel companies and plastics manufacturers.

Cemvita says the biofuel industry is facing feedstock shortages and price fluctuations. Biofuel feedstocks produce starches or sugars that can be converted to produce ethanol, while others produce oil that can be used in biodiesel production, according to the Sustainable Agriculture Research & Education (SARE) program.

“Traditional biofuels, including renewable diesel and sustainable aviation fuel, have relied on oils derived from crops, such as soybean and corn, as well as recycled vegetable oils,” Cemvita says. “As demand grows for petroleum-free alternatives, feedstock is in short supply and must compete with food markets. Crops of soybeans, sugar, and corn use huge swaths of land, and the raw materials require extensive refining — two factors that impede the processes from being sustainable.”

By contrast, eCO2 plants like Cemvita’s can supply feedstock production with minimal land and electricity requirements, and without relying on hydrogen or sunlight, the company says. Furthermore, the output of eCO2 plants is designed to carbon-negative, not just carbon-neutral.

Cemvita’s eCO2 biomanufacturing platform uses engineered microbes that absorb and convert carbon dioxide into feedstocks and finished products.

“The energy transition requires completely new, cost-effective approaches for heavy industry,” Charlie Nelson, chief operating officer of Cemvita, says in a news release. “We built this next-generation pilot plant in response to strong demand from … partners who are actively seeking sustainable solutions to the … feedstock shortage.”

Brother-and-sister team Moji and Tara Karimi founded Cemvita in 2017.

Investors in Cemvita include Oxy Low Carbon Ventures, an investment arm of Houston-based Occidental Petroleum, as well as BHP Group, Mitsubishi, and United Airlines Ventures.

Oxy Low Carbon Ventures and United Airlines Ventures are financing Cemvita’s work on sustainable jet fuel. United Airlines operates a hub at George Bush Intercontinental Airport Houston.

Veronica Wu, founder of First Bight Ventures, joins the Houston Innovators Podcast to outline Houston's opportunities in synthetic biology and biomanufacturing. Photo courtesy

Investor advocates now is the time to position Houston as a leading biomanufacturing hub

houston innovators podcast episode 178

Houston has all the ingredients to be a successful synthetic biology hub, says Veronica Wu. She believes so strongly in this that she relocated to Houston from Silicon Valley just over a year ago to start a venture capital firm dedicated to the field. Since then, she's doubled down on her passion for Houston leading in biotech — especially when it comes to one uniquely Houston opportunity: biomanufacturing.

While Houston's health care innovation scene is actively deploying synthetic biology applications, Wu points to Houston-based Solugen, a plant-based chemical producer, as an example of what Houston has to offer at-scale industrial biomanufacturing. Houston has the workforce and the physical space available for more of these types of biomanufacturing plants, which have a huge potential to move the needle on reducing carbon emissions.

"This is really fundamental technology that's going to change the paradigm and whole dialogue of how we are making a significant impact in reducing a carbon footprint and improving sustainability," says Wu, founder and managing partner of First Bight Ventures, on the Houston Innovators Podcast.

Several aspects — government funding, corporate interest, advances in technology — have converged to make it an ideal time for synthetic biology innovators and investors, Wu explains on the show, and she has an idea of what Houston needs to secure its spot as a leader in the space: The BioWell.

First introduced at a Houston Tech Rodeo event at the Texas Medical Center's Innovation Factory, The BioWell is a public-private partnership that aims to provide access to pilot and lab space, mentorship and programming, and more support that biomanufacturing innovators critically need.

"The way we envision The BioWell is it will provide a holistic, curated support for startups to be able to get across the Valley of Death," Wu says, explaining that startups transitioning from research and development into commercialization need extra support. The BioWell will provide that, as well as allow more engagement from corporations, investors, and other players.

Now that her plans for The BioWell have been announced, Wu is looking for those who want to be a part of it.

She shares more about her mission and what's next for First Bight Ventures on the podcast. Listen to the interview below — or wherever you stream your podcasts — and subscribe for weekly episodes.

San Diego-based rBIO moved to Houston to take advantage of the growing ecosystem of biomanufacturing and synthetic biology. Photo via Getty Images

California-founded biotech startup relocates to join Houston's emerging bioeconomy

new to hou

Cameron Owen had an idea for a synthetic biology application, and he pitched it to a handful of postdoctoral programs. When he received the feedback that he didn't have enough research experience, he decided to launch a startup based in San Diego around his idea. He figured that he'd either get the experience he needed to re-apply, or he'd create a viable company.

After three years of research and development, Owen's path seems to have taken him down the latter of those two options, and he moved his viable company, rBIO, to Houston — a twist he didn't see coming.

“Houston was not on my radar until about a year and a half ago,” Owen says, explaining that he thought of Houston as a leading health care hub, but the coasts still had an edge when it came to what he was doing. “San Diego and the Boston area are the two big biotech and life science hubs.”

But when he visited the Bayou City in December of 2021, he says he saw first hand that something new was happening.

“Companies from California like us and the coastal areas were converging here in Houston and creating this new type of bioeconomy,” he tells InnovationMap.

Owen moved to Houston last year, but rBIO still has an academic partner in Washington University in St. Louis and a clinical research organization it's working with too, so he admits rBIO's local footprint is relatively small — but not for long.

"When we look to want to get into manufacturing, we definitely want to build something here in Houston," he says. "We’re just not to that point as a company."

In terms of the stage rBIO is in now, Owen says the company is coming out of R&D and into clinical studies. He says rBIO has plans to fundraise and is meeting with potential partners that will help his company scale and build out a facility.

With the help of its CRO partner, rBIO has two ongoing clinical projects — with a third coming next month. Owen says right now rBIO is targeting the pharmaceutical industry’s biologics sector — these are drugs our bodies make naturally, like insulin. About 12 percent of the population in the United States has diabetes, which translates to almost 40 million people. The demand for insulin is high, and rBIO has a way to create it — and at 30 percent less cost.

This is just the tip of the iceberg — the world of synthetic biology application is endless.

“Now that we can design and manipulate biology in ways we’ve never been able to before,” Owen says, "we’re really only limited by our own imagination.”

Synthetic biology is a field of science that involves programing biology to create and redesign natural elements. While it sounds like science fiction, Owen compares it to any other type of technology.

“Biology really is a type of software,” he says. “Phones and computers at their core run on 1s and 0s. In biology, it’s kind of the same thing, but instead of two letters, it’s four — A, C, T, and G.”

“The cool thing about biology is the software builds the hardware,” he continues. “You put that code in there and the biology builds in and of itself.”

Owen says the industry of synthetic biology has been rising in popularity for years, but the technology has only recently caught up.

“We’re exploring a brave new world — there’s no doubt about that,” Owen says.

The new development will allow PackGene to nearly triple its Houston-area workforce by the end of the year when the facility is expected to be completed. Photo courtesy of PackGene

Gene therapy company breaks ground on Houston biomanufacturing facility

new to hou

China-based and Massachusetts-founded PackGene Biotech Inc. broke ground last week on a new 25,000-square-foot biomanufacturing and processing facility just south of NRG Park.

The full-service operations center is slated to include labs, manufacturing clean rooms, warehouse, and office space. According to a release from the company, PackGene already employs about 20 people at an existing space in Houston. The new development will allow the company to nearly triple its Houston-area workforce by the end of the year when the facility is expected to be completed.

E&K Building Group is providing design-build services on the project, and the architect of record is Perkins + Will.

"These capabilities will enable us to serve our U.S. customers better and, importantly, to help bring life-saving therapies to patients faster, more reliably, and more cost- effectively. With this, we are making great strides in advancing our mission of 'making gene therapy affordable'," LiYing Yang, PackGene's CTO, says in a statement.

PackGene, which also has facilities in Shanghai and Boston, is a leader in adeno-associated virus (AAV) research, development and manufacturing. It works to accelerate gene therapy product development and works with customers to support gene therapy programs from early-stage therapeutic discovery to clinical trials.

Late last year, a report showed that Houston was expected to see growth in life sciences development, including in the gene therapy manufacturing field. The Texas Medical Center also revealed its plans for the Bioport.

In light of the report, the GHP recommended a few action items, including "accelerating workforce development programs to produce new graduates in key life sciences occupations, refining Houston’s marketing messages to highlight the region’s existing life science assets and activities within life science R&D and manufacturing," per the report. Additionally, the GHP identified the need to develop a shared regional strategy to attract and retain leading life sciences companies.

About a month later, San Jacinto College in Houston announced that it would launch a new College Biotechnology Center at Generation Park in Northeast Houston. The college said the program would offer a specific curriculum in cell and gene therapy as well as hands-on experience in a pilot-scale bioprocessing center.
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CultureMap Emails are Awesome

10+ can't-miss Houston business and innovation events for November

WHERE TO BE

From networking meetups to pitch competitions, November is filled with opportunities for Houston innovators. Here's a roundup of events you won't want to miss out on so mark your calendars and register accordingly.

Note: This post might be updated to add more events.

Featured event: November 14 — Houston Innovation Awards

Celebrate Houston innovation at InnovationMap's 2024 Houston Innovation Awards on November 14 at TMC Helix Park. Click here to read about the finalists. Secure your tickets below.


November 4 - 5 — In-Space Physical AI Workshop

The Rice University Office of Innovation, in partnership with NASA, Purdue University and the Ion District, will host the In-Space Physical AI Workshop. The event will bring together industry leaders, startups, government agencies and researchers to explore the cutting edge of AI in space exploration. Workshop sessions will cover a range of topics in physical AI ⎯ robots or systems that apply AI to autonomously sense, interact with and adapt to their environment using complex computational, sensory and motor abilities to perform challenging real-world tasks.

This event begins Monday, November 4, from 8 am to 8:30 pm at the Ion. Click here to register.

November 6 — Waste to Work: Transforming Waste into Valuable Resources

This event will delve into innovative strategies and technologies that transform waste materials into valuable resources, driving sustainability and economic growth. Topics will include innovative technologies in waste conversion, policy and regulation, economic opportunities in waste management, success stories from around the world, and trends and predictions.

This event is Wednesday, November 6, from 3 to 6 pm at the Cooley University Life Center at UTHealth Houston. Click here to register.

November 7 — Bots & Brews

This event is the fall meetup for the H-town robotics, drones, geospatial, data & AI crowd, hosted by the Energy Drone & Robotics Coalition. Leaders from energy/engineering asset owner/operators, service companies, tech solution providers, startups & investors in the energy and industrial robotics/drone/data & AI community come together to catch up and talk about real-world solutions, projects and deployments.

The event is Thursday, November 7, from 5:30 to 7:45 at The Cannon West. Click here to register.

November 8 — Tech Fest Live

The UH Technology Bridge will be buzzing with students, industry leaders, innovators, and tech enthusiasts as they come together to celebrate the future of technology and innovation. There will be exciting panel discussions, interactive exhibits, and networking opportunities in the fields of digital media, energy, AI and entrepreneurship.

This event is Friday, November 8, from 8 am to 4 pm at UH Technology Bridge. Click here to register.

November 12 — The New Majority Summit

1863 Ventures, a D.C.-based accelerator and venture capital firm, is focused on advancing New Majority entrepreneurs—those historically marginalized or underrepresented—towards greater wealth and success. This immersive program centers on the essential skills and insights needed to transition into becoming an effective CEO.

Throughout the event, registrants will delve into key topics, including the entrepreneurial mindset, understanding one's customer base, establishing scalable processes, financial management strategies, and effective fundraising techniques. Prepare to be inspired and empowered after hearing from 1863 CEO Melissa Bradley, founder & CEO of LAMIK Beauty Kim Roxie, co-founder of Donna's Recipe Gina Woods and more.

This event is Tuesday, November 12, from 8:30 am to 5 pm at the Ensemble Theatre. Click here to register.

November 12 — Software Day at the Ion: Blockchain 2.0: Innovating Across Industries

Software Day is a monthly series driving the support, inspiration, and connections needed to help startups on their path to rapid, sustainable growth. Each month, software day will include office hours (by application), a keynote session, and networking. This software day is moderated by Samantha Lewis, partner at Mercury. Panelists include the former CEO of BBVA Compass, Manolo Sanchez and Ian Epstein, co-CEO ProfitR, global head of capital markets and distribution at republic.

This event is Tuesday, November 12, from 3:30 to 7 pm at the Ion. Click here to register.

November 13 — Envision 2024

Learn how companies in the ecosystem of the largest medical center in the world are addressing challenges head-on, meet some of our entrepreneurs, and network. This event is presented in partnership with Innovate UK and BioInnovation Institute.

This event is Wednesday, November 13, from 1 to 5 pm at TMC Innovation Factory. Click here to register.

November 14 — State of the Texas Medical Center

The Greater Houston Partnership's State of the Texas Medical Center returns. William F. McKeon, President and CEO of the Texas Medical Center, will deliver an annual address, discussing the tremendous progress in discovery and life sciences at the world's largest medical center. New to this year's State of the Texas Medical Center, is a dynamic pitch competition, the TMC Innovation Pitch Tank.

This event is Thursday, November 14, from 11 am to 1:30 pm at Hilton Americas. Click here to register.

November 15 — 2024 ERG Symposium

This event, hosted by Houston Methodist, will include a keynote from Shona Pinnock, VP of DEI for Peloton as well as insights from other local organizations such as HESS, Houston Methodist, TDECU, Greystone and more. These experts will share how ERGS are impacting business goals, enhancing company culture and employee engagement and will provide valuable insights and actionable takeaways to help organizations maximize the effectiveness of ERGs.

This event is Friday, November 15, from 9 am to 1 pm at The Westin Houston Medical Center. Click here to register.

November 19 — A Texas Talk: Reflecting on the Past, Envisioning the Future

Center for Houston’s Future’s signature fall event, Dinner and Conversation presented by Harvey-Cleary, will feature an exciting conversation between two important Texas voices. Stephen Harrigan, the award-winning author of 12 fiction and non-fiction books, will appear in conversation with Sonal Shah, CEO of the Texas Tribune, who has a long record of social impact work across multiple sectors.

This event is Tuesday, November 19, from 6 to 9 pm at the River Oaks Country Club. Click here to register.

November 21 — Visionary Voices: A Fireside Chat with Dan Ammann, President of ExxonMobil Low Carbon Solutions

In this fireside chat, Dan Ammann, president of ExxonMobil Low Carbon Solutions, will discuss ExxonMobil’s plans in advancing a thoughtful energy transition by delivering the critical energy and products the world needs and reducing their own and others’ greenhouse gas emissions. He’ll talk about Low Carbon Solutions’ transformative projects and investments aimed at bringing lower-emission technologies like hydrogen, lithium, and carbon capture and storage to market, making them accessible to carbon-intensive industries worldwide.

This event is Thursday, November 21, from 8 to 10 am at the Ion. Click here to register.

Overheard: Houston's top energy transition founders explain their biggest challenges

Houston Innovation Awards

From finding funding to navigating the pace of traditional oil and gas company tech adoption, energy transition companies face their fair share of challenges.

This year's Houston Innovation Awards finalists in the Energy Transition category explained what their biggest challenge has been and how they've overcome it. See what they said below, and make sure to secure your tickets to the Nov. 14 event to see which of these finalists win the award.

"The evolving nature of the energy industry presents opportunities to solve some of our industry's greatest challenges. At Amperon we help optimize grid reliability and stability with the power of AI demand forecasting."

Sean Kelly, CEO of Amperon, an AI platform powering the smart grid of the future

"The biggest challenge in leading an energy transition-focused startup has been balancing the urgency for sustainable solutions with the slow pace of change in traditional industries like oil and gas. Many companies are cautious about adopting new technologies, especially when it comes to integrating sustainability initiatives. We overcame this by positioning our solutions not just as environmentally friendly, but as tools that improve safety, efficiency, and cost savings. By aligning our value proposition with their operational goals and demonstrating real, measurable benefits, we were able to gain traction and drive adoption in industries that are traditionally resistant to change."

— Dianna Liu, CEO of ARIXTechnologies, an integrated robotics and data analytics company that delivers inspection services through its robotics platforms

"Scaling up production of hard tech is a major challenge. Thankfully, we recruited top-notch talent with experience in technology scale-up and chemical processes. In addition, we've begun building partnerships with some of the world's largest chemical manufacturers in our space who are excited to be a part of our journey and could rapidly accelerate our go to market strategy. We have significant demand for our product as early as 2025, so partnering with these companies to scale-up will bring our technology to market years ahead of doing it alone."

— Matthew Dawson, CEO of Elementium Materials, a battery technology with liquid electrolyte solutions

"Our pyrolysis reactor is a proprietary design that was developed during Covid. We ran simulations to prove that it works, but it was not easy to test it in a pilot facility, let alone scaling it up. We managed ... to run our pilot plant studies, while working with them remotely. We proved that our reactor worked and produced high quality products. Later, we built our own pilot plant R&D facility to continue running tests and optimizing the process. Then, there was the challenge of scaling it up to commercial size. ... We put together a task force of four different companies to come together to design and build this complex reactor in record time."

— Vibhu Sharma, CEO of InnoVentRenewables, a startup with proprietary continuous pyrolysis technology that converts waste tires, plastics, and biomass into valuable fuels and chemicals

"Energy storage and geothermal power generation are capital-intensive infrastructure projects, requiring investors with a deep commitment and the patience in terms of years to allow the technology to be developed and proven in the field. One challenge is finding that niche of investors with the vision to join our journey. We have succeeded in raising our $30 million series A with these types of investors, whom we’re confident will continue the journey as we scale."

— Cindy Taff, CEO of SageGeosystems, an energy company focused on developing and deploying advanced geothermal technologies to provide reliable power and sustainable energy storage solutions regardless of geography

"The biggest challenge we've faced has been to bring together massive independent power producers on one side who are investing hundreds of millions of dollars into grid infrastructure with multi- national tech giants on the other that don't have experience working much with energy storage. As a startup with only four employees, gaining credibility with these players was critical. We overcame this hurdle by becoming the preeminent thought leader on storage emissions, through publishing white papers, discussing the issues on podcasts, and (more)."

— Emma Konet, CTO of TierraClimate, a software provider that helps grid-scale batteries reduce carbon emissions

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This article originally ran on EnergyCapital.