It's a blast to work at Johnson Space Center. Johnson Space Center/Facebook

Houston continues to prove it hosts the best of the best employers in Texas as NASA tops Forbes' 2023 list of "America’s Best Employers By State."

The highly anticipated list, published August 22, is a collaboration between Forbes and Statista to survey the satisfaction levels of tens of thousands of workers employed by national companies.

Though the government agency is based in Washington, D.C., NASA's stratospheric presence in Houston (coupled with a great work environment and advancement opportunities) is what propels it to the top year after year. There are currently more than 17,000 workers employed by NASA, according to Forbes.

Earlier this year, NASA was honored as the Best Place to Work in the Federal Government by the Partnership for Public Service for its unyielding dedication to space exploration and discovery.

"The passion and precision of our workforce makes NASA the best place to work in the federal government," said NASA Administrator Bill Nelson in a statement. "Together, we are poised to accomplish more daring feats with new advancements, more scientific contributions on Earth and in the heavens, and more incredible technological breakthroughs that will help shape the 21st century."

While Forbes explains that the national list isn't the same as their best large employers list, it's meant to serve as an in-depth analysis of companies that are "closer-to-home options for every American worker."

NASA's high rank follows shortly after the agency launched a brand new Digital Engineering Design Center fully dedicated to innovating the future of spaceflight. The new center will aid in expanding opportunities for the younger generation to embrace aerospace engineering as a career.

Forbes and Statista determined their rankings by surveying 70,000 Americans working at employers in the U.S. with at least 500 employees each. The final list features 1,392 highly recommended employers in the 50 states and the District of Columbia. Nearly 270 employers ranked highly in multiple states.

Here are the 30 best large employers in Texas, as determined by Forbes and Statista:

Houston area:

  • No. 1 – NASA (based in Washington, D.C.; Johnson Space Center in Clear Lake)
  • No. 4 – Houston Community College
  • No. 5 – Houston Methodist
  • No. 6 – Texas Children's Hospital
  • No. 18 – National Oilwell Varco
  • No. 19 – Bechtel (based in Reston, Virginia; major corporate hub in Houston)

Dallas-Fort Worth:

  • No. 6 – Texas Oncology, based in Dallas
  • No. 9 – Fidelity Investments (based in Boston; major corporate hub in Westlake)
  • No. 14 – Capital One (based in Richmond, Virginia; major corporate hub in Plano)
  • No. 17 – University of Texas Southwestern Medical Center in Dallas
  • No. 22 – Southwest Airlines, based in Dallas
  • No. 24 – Texas Health Resources, based in Arlington
  • No. 25 – General Motors (based in Detroit, Michigan; major assembly hub in Arlington)
  • No. 27 – City of Plano
  • No. 28 – Toyota North America, based in Plano

San Antonio:

  • No. 2 – H-E-B (based in San Antonio; more than 300 stores in Texas)
  • No. 26 – University of Texas Health Science Center at San Antonio

Austin:

  • No. 3 – Google (based in Mountain View, California; major corporate hub in Austin)
  • No. 13 – Apple (based in Cupertino, California; major corporate hub in Austin)

Throughout Texas:

  • No. 8 – Salesforce (based in San Francisco, California; offices in Austin and Dallas)
  • No. 10 – IKEA (based in Sweden; five stores in Texas)
  • No. 11 – Costco (based in Issaquah, Washington; 38 stores in Texas)
  • No. 15 – Cardinal Health (based in Dublin, Ohio; 23 locations in Texas)
  • No. 16 – Microsoft (based in Redmond, Washington; offices in Austin, Dallas, Friendswood, Frisco, Houston, San Antonio, and The Woodlands)
  • No. 20 – Leidos (based in Reston, Virginia; locations in San Antonio, Houston, and Webster)
  • No. 21 – Cisco Systems (based in San Jose, California; offices in Austin, Dallas, Irving, Richardson, Houston, Laredo, and San Antonio)
  • No. 23 – IBM (based in Armonk, New York; offices in Austin, Houston, Dallas, and Frisco)
  • No. 29 – Nike (based in Beaverton, Oregon; 26 locations in Texas)
  • No. 30 – Charles Schwab (based in San Francisco, California; 25 locations in Texas)
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This article originally ran on CultureMap.
It pays to work at these four Houston companies. Coalition for the Homeless of Houston/Facebook

4 Houston companies clock in among America’s best employers, says Inc.

happy workers

Houston has already been heralded as a hotbed for innovation. Now, a handful of local companies are in the spotlight as the best places to work.

Four Houston companies are among 429 businesses named May 12 to Inc. magazine's 2021 list of the country's best workplaces. They are:

  • Marketing and PR firm CKP, Houston.
  • Environmental restoration company Ecosystem Planning and Restoration, Tomball.
  • IT automation platform Liongard, Houston.
  • Online recruiting service WizeHire, Houston.

"We've taken steps, especially during the pandemic, to build an amazing team and inclusive culture that is rooted in collaboration," Liongard CEO Joe Alapat says in a news release. "I am proud every day of the work this team is doing and the positive impact we're having on the managed services industry, and thrilled that our employees share our excitement and enthusiasm."

Meanwhile, 11 Austin companies receiving kudos are:

  • 9Gauge Partners, a business management consulting firm.
  • AgileAssets, a provider of transportation management software.
  • AlertMedia, an emergency communication and monitoring platform.
  • Decent, a provider of health insurance.
  • Fourlane, a provider of QuickBooks support.
  • Made In Cookware, an e-commerce startup that sells pots, pans, and other cookware.
  • Mighty Citizen, a branding, marketing, and communications firm.
  • OJO Labs, a platform for buying and selling homes.
  • Ontic, a company whose software helps companies address physical threats.
  • Q1Media, a digital media company.
  • The Zebra, an insurance marketplace.

Nick Soman, founder and CEO of Decent, says his company seeks to trust, respect, and appreciate every employee.

"This year that has meant quickly helping employees who lost power during an unprecedented snowstorm find a warm place to stay and offering unlimited time off," Soman says in a news release. "Being recognized as a top workplace is a special honor for Decent. Our people are at the heart of our company. They foster our amazing culture and drive our consistently outstanding customer service."

Lukas Quanstrom, CEO of Ontic, says his company is committed to upholding the core values, standards, and practices that contributed to the Inc. honor.

"Over the past year, the Ontic team has experienced rapid growth reinforcing how important our supportive, entrepreneurial culture is to nurturing talent and prioritizing our employees' overall welfare," Quanstrom says in a news release.

Each nominated company took part in an employee survey, conducted by Quantum Workplace, on topics including management effectiveness, perks, and employee growth. Also, an organization's benefits were audited to help determine the employer's standing.

Elsewhere in Texas, seven Dallas-Fort Worth employers, four Houston-area employers, and one San Antonio employer made the Inc. list.

Dallas-Fort Worth area

  • Staffing and recruiting firm BridgeWork Partners, Dallas.
  • Commercial real estate services company esrp, Frisco.
  • Staffing agency Frontline Source Group, Dallas.
  • PR and marketing firm Idea Grove, Dallas.
  • HVAC and plumbing warranty company JB Warranties, Argyle.
  • Technical consulting firm Stratosphere Consulting, Dallas.
  • NetSuite consulting firm The Vested Group, Plano.

Inc. highlights esrp's employee emergency fund, which offers "a financial lifeline for a range of life events, including funerals, medical emergencies, and welcoming new grandchildren. The omnipresent resource is funded through anonymous employee donations."

San Antonio

The only San Antonio company to make the 2021 list was IT services provider Mobius Partners.

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This article originally ran on CultureMap.

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Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance and co-founder of Station Houston, beginning April 15. Reale is co-founder of the Station Houston startup hub and a startup investor and was also recently named director for startups and investor engagement for the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."