University of Houston spinout's smartphone COVID-19 test to head to market

Pandemic innovation

Luminostics, which was founded out of a lab at UH, received NIH grant to produce its COVID-19 rapid antigen test. Photo courtesy of Luminostics

A Silicon Valley startup with Houston roots is helping tackle the COVID-19 pandemic with its smartphone-based coronavirus test.

Milpitas, California-based Luminostics, a University of Houston spinout, is producing millions of its Clip COVID Rapid Antigen Test for U.S. consumers after receiving emergency authorization for the product in December. The emergency approval closely followed the National Institutes of Health awarding a $26.1 million contract to Luminostics to speed up development of the coronavirus test. According to a news release from UH, Luminostics is working on an affordable next generation hardware system to reach the mass over-the-counter market at scale.

Chemical engineers and UH alumni Bala Raja, the CEO, and Andrew Paterson, the chief technology officer, began forming their company in the UH lab of Richard Willson, a professor of chemical and biomolecular engineering and professor of biochemical and biophysical sciences.

The technology developed in the UH lab aims to equip consumers with rapid self-diagnostic tests for the flu, HIV, herpes, and other conditions by detecting the presence of bacteria, viruses, small molecules, hormones, and proteins. But Raja and Paterson put that strategy on hold last year and pivoted to re-engineering their technology for COVID-19 testing. The result: the Clip COVID Rapid Antigen Test.

"When we realized that COVID wasn't just a bad flu and that it was actually gonna go crazy and affect as many people as it has, we decided that everything we've done could be very quickly repurposed to make two different tests," Raja told Inc. magazine in April.

UH alumni Andrew Paterson and Bala Raja are co-founders of Luminostics. Photo via UH.edu

As UH explains, the Clip COVID test relies on a nasal swab, a smartphone clip, and glow-in-the-dark nanoparticles to detect a coronavirus infection within 30 minutes. In the phone, an image processor measures the intensity of the luminescence signal. If the signal is strong enough, the result is positive. If it's weak, the result is negative.

"We live in a world where you can have all your basic necessities delivered to your home through an app, and yet this pandemic has exposed how far behind the diagnostics industry lags compared to consumer technology and the convenience economy," Paterson tells UH.

Funding from the National Institutes of Health, venture capital firm Khosla Ventures, investment firm Lynette Capital, and startup accelerator Y Combinator has helped support the Clip COVID Rapid Antigen Test. The startup entered the Y Combinator program in 2016, a year after Raja and Paterson established Luminostics.

In April 2020, French pharmaceutical giant Sanofi said it was exploring a collaboration with Luminostics on the COVID-19 test.

"The diagnostics industry is saturated with products that cater to big, centralized labs or testing in the doctor's office," Paterson says. "There are many applications where it does make sense to do testing in a centralized lab, but there are dozens of other applications where there should be home-tests and there are not, because few companies have tried to take on the technical and regulatory challenges with developing home-testing."

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10+ can't-miss Houston business and innovation events for April

WHERE TO BE

From pitching competitions to expert speaker summits, April is filled with opportunities for Houston innovators.

Here's a roundup of events you won't want to miss out on so mark your calendars and register accordingly.

Note: This post may be updated to add more events.

April 4 — Mission Control: Texas’ Leadership in Space, Technology, and Innovation

Since its inception, the space industry has expanded across Texas and grown beyond scientific exploration into a tableau on which the terrestrial set have placed bets related to tourism, mining, communications, healthcare, food science, national security, technical innovations across all industries, and even human habitation beyond earth. The Texas Lyceum’s 2024 Public Conference (PubCon) will explore these opportunities and the journey to realize the promise of space and beyond for Texas and the nation.

Throughout the event, an expected 300 industry leaders and Texas legislators and staffers will participate in thought provoking discussions to inform our stakeholders and state leaders on the trajectory, challenges and opportunities in the Space Economy.

This event starts Thursday, April 4, from 2:30 to 9:30 pm at the Thompson Hotel. Click here to register.

April 4-6 — 2024 Rice Business Plan Competition

Hosted and organized by the Rice Alliance for Technology and Entrepreneurship, which is Rice University's internationally-recognized initiative devoted to the support of entrepreneurship, and Rice Business, the Rice Business Plan Competition offers an educational program mirroring real-world experience through this multi-day event for student startups from across the world.

In total, more than $1 million in investment and cash prizes are expected to be awarded at the 2024 Rice Business Plan Competition. Every single startup will walk away with at least $950 in cash prizes, no matter where they place in the competition.

The Elevator Pitch event is open to the public and on Thursday, April 4, from 6 to 9 pm at Jones Graduate School of Business. Click here to register.

April 6 — 12th Annual Houston Global Health Collaborative Conference

This meeting is an annual gathering of interdisciplinary professionals and students with a passion for global health innovation and advancement. This year's Conference Theme is Global Health Diplomacy: Shaping Policies for Health Impact and will feature subthemes of vaccine diplomacy, global surgery, the prevalence of non-communicable diseases, and the global nutrition crisis. Clinicians, researchers, healthcare workers, policymakers, and students across any field who are interested in global health are especially encouraged to attend.

This event is Saturday, April 6, from 7:45 am to 7 pm at the University of Houston College of Medicine. Click here to register.

April 10 — Bayou City Bio Pulse

Check out a showcase of life sciences in The Woodlands. This event will feature a vendor exhibition, presentations from business, academic and community development leaders, and a panel discussion on The Woodlands’ life sciences ecosystem. Spanning across five sites totaling over 80 acres, The Woodlands Innovation District is positioned to meet the needs of companies focused on in-house manufacturing (from biopharma to industrial biology), as well as contract development manufacturing organizations (CDMOs).

This event is Wednesday, April 10, from 8 am to 12 pm at the Woodlands Towers. Click here to register.

April 18 — Energy Underground: All Things Hydrogen

The Energy Underground is a group of professionals in the Greater Houston area that are accelerating the Energy Transition. Come together to learn and support each other's work in advancing the Energy Transition: make industry contacts, secure financing, share deals, recommend talent looking to enter the energy workforce, and anything else that leads to bigger, better energy companies.

This event is Thursday, April 18, from 12 to 1:30 pm at the Cannon West Houston. Click here to register.

April 19 — Build Day x Tour: Houston Hackathon

A partnership between ACT House, a human analytics leader, and Tech Equity Collective, a Google Initiative driving black innovation in tech formed an exciting new accelerator. Participants will build their own startup team, collaborate on ideas, and sprint on real work. The first place winning team will receive $10,000, the second place team will recieve $5,000 and the third place team will get $2,500.

This event is Friday, April 19, at 4 pm until April 20 at 4 pm. Click here to register.

April 21 — The Energy Corridor District's Earth Day Celebration

Come out for a day of fun and environmental awareness. Get hands-on and contribute to a communal art piece that symbolizes a collective commitment to Mother Earth. Pick up a brush or a marker and add your creativity to the canvas.

Take a moment to learn how the world's top energy companies are contributing to a more sustainable future. Get inspired and pick up some tips for your own eco-journey

This event is Sunday, April 21, from 1 to 4 pm at Terry Hershey Park. Click here to register.

April 22 — EO4Energy Workshop

The Geological Remote Sensing Group (GRSG) Americas, in partnership with the University of Houston, invites you to a workshop focusing on the role of Earth Observation (EO) and remote sensing in the Energy Industry.

As the industry moves towards sustainability, driven by Environmental, Social, and Governance (ESG) considerations, the significance of EO and remote sensing continues to grow. This workshop will encompass insightful case studies, introduce emerging technologies, and present advanced methodologies. Participants will engage with a diverse group of professionals from the energy, space, academic, and government sectors.

This event begins Monday, April 22, at 8 am at Hilton University of Houston. Click here to register.

April 25 — 2024 PIDX International US Spring Conference

In this industry event, explore the intersection of AI and Digital Standards. All experienced speakers across industries are invited to contribute articles, share use cases and theories, and connect with attendees from the Energy Industry.

The accumulated knowledge shared at the event will guide the forthcoming phase of PIDX Standards Development tailored for the Energy Industry.

This event begins Thursday, April 25, at 8 am at 501 Westlake Park. Click here to register.

April 26 — StartupLaunch USA: Ignite Your Entrepreneurial Journey

This is an immersive online learning experience tailored for aspiring entrepreneurs looking to kickstart their startup ventures in the United States. This event provides participants with the essential knowledge, skills, and resources needed to navigate the complexities of launching and scaling a successful business.

Through a series of interactive workshops, expert-led seminars, and practical case studies. Participants will learn how to develop innovative business ideas, validate market opportunities, and create viable business models that resonate with target audiences.

This event is Friday, April 26, from 1 to 6 pm at Museum of Natural Science. Click here to register.

April 27 — World Youth Foundation: STEAM Innovation Incubator

WYF's STEAM Innovation Industry Pathways, or SIIP, is a youth out-of-school-time monthly program designed to bridge the gap between academic learning, industry, and digital skilling.

Open to youth ages 6 to 24, SIIP is not your typical program—it's a gateway to a world of metaskilling, offering a dynamic range of skills from design thinking, strategic project management, soft skills development, digital skills development, and industry application.

This event is Saturday, April 27, from 10 am to 1:30 pm at Sunnyside Health and Multi-Service Center. Click here to register.

Report: Here's how Houston ranks in terms of its gender pay gap

by the numbers

It's 2024 and women are still making less money than men, thus keeping the unfortunate reality of the wage gap alive. But at least in Houston, the wage gap isn't as bad as other Texas cities, according to a new earnings study by Chamber of Commerce.

Houston ranked No. 142 on the list, which examined earnings for full-time workers in 170 of the most populous cities in the United States.

The study found that, in 2024, men in Houston are currently making $4,474 more than women — a figure that's significantly lower than the national wage gap, which is a little over $11,000.

The U.S. city with the worst gender pay gap is none other than Frisco, a Dallas suburb. Men in Frisco are currently making a staggering $52,216 more than women, which is more than $12,000 more than the gap in 2023.

Also in North Texas, McKinney remained in the No. 5 spot for the second consecutive year. McKinney men make $24,568 more than women, which is a $4,400 decrease year-over-year. Plano's gender wage gap has worsened since 2023: The Dallas suburb is now listed among the top 10 worst pay gaps in the U.S., climbing to No. 6. The study says the Plano's wage gap is now $23,415, or nearly $2,300 more than last year.

Statewide gender pay gap

Chamber of Commerce found that Texas' gender pay gap has increased since last year; The 2023 study found that women made nearly $11,000 less than men, and that discrepancy has widened in 2024 to nearly $12,000.

However, Texas' ranking has improved 10 spots from No. 29 last year to No. 19 this year.

For added context, New Hampshire has the No. 1 worst pay gap in the nation, with men making over $18,000 more than women.

Other Texas cities that earned spots in the report are:

No. 20 – Amarillo
No. 22 – Laredo
No. 24 – Austin
No. 30 – Corpus Christi
No. 31 – Pasadena
No. 33 – Irving
No. 52 – Lubbock
No. 59 – El Paso
No. 65 – Grand Prairie
No. 81 – Fort Worth
No. 118 – Dallas
No. 121 – San Antonio
No. 125 – Arlington
No. 167 – Brownsville
No. 168 – Garland

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This article originally ran on CultureMap.

3 Houston innovators to know this week

who's who

Editor's note: Welcome to another Monday edition of Innovators to Know. Today I'm introducing you to three Houstonians to read up about — three individuals behind recent innovation and startup news stories in Houston as reported by InnovationMap. Learn more about them and their recent news below by clicking on each article.

Sean Kelly, CEO and co-founder of Amperon

Amperon CEO Sean Kelly joins the Houston Innovators Podcast to share his company's growth and expansion plans. Photo via LinkedIn

The technology that Amperon provides its customers — a comprehensive, AI-backed data analytics platform — is majorly key to the energy industry and the transition of the sector. But CEO Sean Kelly says he doesn't run his business like an energy company.

Kelly explains on the Houston Innovators Podcast that he chooses to run Amperon as a tech company when it comes to hiring and scaling.

"There are a lot of energy companies that do tech — they'll hire a large IT department, they'll outsource a bunch of things, and they'll try to undergo a product themselves because they think it should be IP," he says on the show. "A tech company means that at your core, you're trying to build the best and brightest technology." Continue reading.

Amanda Burkhardt, CEO of Phiogen

Spun out of Baylor College of Medicine, Phiogen was selected out of 670 companies to pitch at SXSW earlier this month. Photo via LinkedIn

A new Houston biotech company won a special award at the 16th Annual SXSW Pitch Award Ceremony earlier this month.

Phiogen, one of 45 companies that competed in nine categories, was the winner for best inclusivity, much to the surprise of the company’s CEO, Amanda Burkhardt.

Burkhardt tells InnovationMap that while she wanted to represent the heavily female patient population that Phiogen seeks to treat, really she just hires the most skilled scientists.

“The best talent was the folks that we have and it ends up being we have three green card holders on our team. As far as ethnicities, we have on our team we have Indian, African-American, Korean, Chinese Pakistani, Moroccan and Hispanic people and that just kind of just makes up the people who helped us on a day-to-day basis,” she explains. Continue reading.

Mielad Ziaee, 2023-2024 All of Us Research Scholar

Mielad Ziaee, a 20-year-old student at the University of Houston, was tapped for a unique National Institutes of Health program. Photo via UH.edu

A Houston-area undergraduate student has been tapped for a prestigious national program that pairs early-career investigators with health research professionals.

Mielad Ziaee was selected for the National Institutes of Health’s 2023-2024 All of Us Research Scholar Program, which connects young innovators with experts "working to advance the field of precision medicine," according to a statement from UH. Ziaee – a 20-year-old majoring in psychology and minoring in biology, medicine and society who plans to graduate in 2025 — plans to research how genomics, or the studying of a person's DNA, can be used to impact health.

“I’ll be one of the ones that define what this field of personalized, precision medicine will look like in the future,” Ziaee said in a statement. “It’s exciting and it’s a big responsibility that will involve engaging diverse populations and stakeholders from different systems – from researchers to health care providers to policymakers.” Continue reading.

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