Texas high-speed bullet train has some fresh financial fuel. Photo of the N700 courtesy of © JR Central

Amtrak and its partners will receive more than $2.1 billion in a federal program to improve existing routes and expand Amtrak service across the U.S.

That includes $500,000 from the Federal Railroad Administration awarded to the long-in-the-works high-speed rail project between Houston and Dallas, as well as another $500,000 awarded to the I-20 Corridor Long-Distance Passenger Rail Project.

The funding is via the newly-passed Infrastructure Investment & Jobs Act and includes multiple grants that will go to Amtrak and partners. This includes:

  • $108.5 million to Amtrak for station and service upgrades;
  • $2 billion to Amtrak partners in North Carolina, Virginia, Pennsylvania, and Maine for infrastructure upgrades
  • $34.5 million to 39 states and localities for planning and development of 69 new and improved intercity passenger rail corridors

These grants were awarded through the Federal Railroad Administration’s Federal-State Partnership for Intercity Passenger Rail Program for projects located across the National Network, as well as the Corridor Identification and Development Program (Corridor ID).

FRA Administrator Amit Bose says in a statement that these will be "transformative rail projects" that will provide climate-friendly alternatives to congested roads and airports.

“Today’s investments in passenger rail nationwide, made possible by the President’s Bipartisan Infrastructure Law, are another step forward as we expand and modernize our country’s rail network, providing more Americans the world-class passenger rail they need and deserve," Bose says.

Amtrak was awarded funding on a variety of projects, including four Corridor programs, designed to create a pipeline of intercity passenger rail projects.

Those include:

  • Texas High-Speed Rail Corridor. This proposed corridor would connect Houston and Dallas, Texas, with a new, dedicated and grade separated high-speed passenger rail service. This would provide new service on a new alignment, with station stops in Dallas, Brazos Valley and Houston.
  • Long Island Northeast Regional Extension. This proposed corridor would extend three existing daily Northeast Regional round trips between Washington, DC and New York City east to Ronkonkoma, NY, with stops at Jamaica (Queens, NY) and Hicksville, NY. This would entail track, station and infrastructure upgrades to accommodate these trains and better integrate Amtrak service with Long Island Rail Road commuter service.
  • Daily Cardinal Service. This proposed corridor would increase Cardinal service to operate daily, versus three days per week currently. This route operates between New York City and Chicago via Philadelphia, Baltimore, Washington, DC, Virginia, West Virginia, Kentucky, Ohio and Indiana.
  • Daily Sunset Limited Service. This proposed corridor would increase Sunset Limited service to operate daily, versus three days per week currently. This route operates between Los Angeles and New Orleans via Houston, San Antonio and El Paso, Texas; Tucson, Ariz.; and other communities.

The release does not say exactly how the $500,000 will be used. According to TxDOT, the current estimate for construction of track between Houston and Dallas is approximately $16 billion.

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This article originally ran on CultureMap.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.