Houston-based Accel Lifestyle's innovative line of athleisure has made it into Talbots. Photo courtesy of Accel

After a year of planning and behind-the-scenes work, the highly anticipated collaboration between local apparel brand Accel Lifestyle and Talbots has finally come to fruition.

Shoppers can now find Accel Lifestyle apparel — beloved for its eco-friendly, sustainable, antibacterial fabrics sourced made in the USA — on Talbot's website.

This partnership marks the first-ever collaboration for the athleisure brand of Talbots, T by Talbots. By teaming up with Accel Lifestyle, Talbots expands its product offerings and also provides its loyal, forward-thinking, and ethically minded customers with a new clothing option that perfectly fits with their values.

At the helm of Accel Lifestyle is founder Megan Eddings, whose background in chemistry ignited the creation of the brand's groundbreaking Prema fabric after one too many run-ins with foul-smelling gym clothes. Her proprietary fabric boasts a revolutionary antibacterial technology, rendering Accel Lifestyle's apparel supremely comfortable, high-quality, and remarkably odor-resistant. With this cutting-edge fabric, Accel Lifestyle firmly establishes itself as a trailblazer in the industry, setting new standards for functionality and style.

As CultureMap reported in 2019, Eddings's innovative work was rewarded with a partnership with Inc. Magazine, Houston billionaire Tilman Fertitta, and others.

Amanda Cotler and Megan Eddings of Accel Lifestyle are celebrating a big win for their company. Photo courtesy

"We are beyond elated about the Accel x Talbots launch," Eddings tells CultureMap." Amanda Cotler, Accel's Director of Operations, and I have been working on this opportunity for a year, and it feels incredible for the collaboration to be live. Our passions are textiles with technology and an ethical made-in-the-USA supply chain. To have a multi-billion dollar company like Talbots care about the same things brings us so much joy."

In addition to their remarkable achievements in fashion, Accel Lifestyle champions the power of women in STEM through their team's leadership and this collaboration. By showcasing the applications of science and technology within the realm of fashion, Accel Lifestyle and Talbots are spotlighting the remarkable potential within these fields.

With the Accel Lifestyle x Talbots collaboration in full swing, customers can expect an extraordinary fusion of sustainable fashion and impeccable style. The Accel Lifestyle collaboration features an Anti-Odor Power Tank and an Anti-Odor Timeless Tee. Both are available in colors black and white.

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This article originally ran on CultureMap.

This week's Houston innovators to know include Megan Eddings and Amanda Cotler of Accel Lifestyle and Brad Burke of Rice Alliance. Photos courtesy

3 Houston innovators to know this week

Who's who

It seems like 2020 is the year of the pivot and taking what the world has thrown at you —from pandemics to oil gluts — and making something out of what you have.

This week's innovators to know include a Houston startup flipping the switch on production to make face masks to the Rice Alliance re-envisioning an annual event that usually takes place at a global conference.

Megan Eddings and Amanda Cotler of Accel Lifestyle

Photos courtesy

When Megan Eddings and Amanda Cotler saw the CDC was recommending medical professionals wear bandanas or strips of cloth when surgical face masks weren't available, they had an idea.

The duo behind Accel Lifestyle, a Houston-based athletic wear startup that has a bacteria-resistent fabric, hopped on a call to see how they could rework their supply chain to quickly pivot to making face masks.

When setting up the company, Eddings, Accel's founder, made it a priority to avoid sweatshops, and she set up her supply chain to be completely within the United States — something that's been beneficial to the company's COVID pivot.

"If we did not have a 100 percent domestic supply chain, there's no way we could have done this," Eddings says.

Eddings and Cotler joined the Houston Innovators Podcast to share the story of how Accel went from deciding to make the masks to selling them by the thousands to Houston Methodist.

"When you think of face masks, you wouldn't think about activewear or thinking of Accel being a part of the fight against coronavirus," Cotler says. However, that might no longer be the case for the company now. Click here to learn more and to stream the podcast episode.

Brad Burke, managing director of the Rice Alliance for Technology and Entrepreneurship

Photo via alliance.rice.edu

Rice Alliance for Technology and Entrepreneurship typically hosts their Energy Tech Venture Day from the one of the halls within NRG Arena at the annual Offshore Technology Conference. However, the conference that attracts thousands of people from around the world, much like so many events, was canceled due to coronavirus.

But Brad Burke and his team at the Rice Alliance turned to tech to introduce the first virtual event, which then took place on Thursday, May 7. Burke introduced the event that had 39 startups that represented 11 different states and six different countries, 13 call Houston their HQ.

"We had many startups and corporations reach out to us and ask us if we could go ahead with the event in a virtual format, so that's how we ended up where we are today," says Burke. Click here to read more.

Megan Eddings and Amanda Cotler of Accel Lifestyle join the Houston Innovators Podcast to share how they pivoted from making T-shirts to face masks. Photos courtesy

From T-shirts to facemasks, how this Houston startup quickly made its COVID-19 pivot

HOUSTON INNOVATORS PODCAST EPISODE 30

Startups across Houston have made the decision to pivot their business or technology amid the COVID-19 crisis — both to stay afloat in the shutdown and to contribute to the community.

Houston-based Accel Lifestyle, an athletic wear company that has designed a bacteria-resistant material, flipped a switch on its production to make face masks `rather than T-shirts and tanks with their Prema fabric. On the latest episode of the Houston Innovators Podcast, Megan Eddings, founder and CEO, and Amanda Cotler, director of operations, shared the story of how this pivot came to be.

"When you think of face masks, you wouldn't think about activewear or thinking of Accel being a part of the fight against coronavirus," Cotler says.

But when Cotler and Eddings saw the Center for Disease Control was recommending wearing bandanas and cloth when face masks weren't available, they had an epiphany.

"Megan and I read that and immediately hopped on a call with our team," Cotler says. "We had a realization with our antibacterial fabric that a face mask made from it would be so much cleaner."

Within 24 hours, the duo had a sample in their hands, and they had 14,000 yards of their Prema fabric being shipped from California to Houston, where they had managed to find 60 local sewers ready to start making the masks.

When setting up the company, Eddings made it a priority to avoid sweatshops, and she set up her supply chain to be completely within the United States — something that's been beneficial to the company's COVID pivot.

"If we did not have a 100 percent domestic supply chain, there's no way we could have done this," Eddings says.

Packs of 10 masks are available online, but the bulk of Accel's mask sales have been to hospitals like Houston Methodist, which has ordered thousands.

Now, with the Houston workforce making moves to return to the work place, Eddings says she's seen an increased interest in corporations wanting custom masks with the company logo on it for their employees.

Eddings and Cotler share the story of Accel and its ability to pivot amid a national crisis on the podcast. Stream the episode below or wherever you get you podcasts — just search for the Houston Innovators Podcast.


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Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”