Houston-based Accel Lifestyle's innovative line of athleisure has made it into Talbots. Photo courtesy of Accel

After a year of planning and behind-the-scenes work, the highly anticipated collaboration between local apparel brand Accel Lifestyle and Talbots has finally come to fruition.

Shoppers can now find Accel Lifestyle apparel — beloved for its eco-friendly, sustainable, antibacterial fabrics sourced made in the USA — on Talbot's website.

This partnership marks the first-ever collaboration for the athleisure brand of Talbots, T by Talbots. By teaming up with Accel Lifestyle, Talbots expands its product offerings and also provides its loyal, forward-thinking, and ethically minded customers with a new clothing option that perfectly fits with their values.

At the helm of Accel Lifestyle is founder Megan Eddings, whose background in chemistry ignited the creation of the brand's groundbreaking Prema fabric after one too many run-ins with foul-smelling gym clothes. Her proprietary fabric boasts a revolutionary antibacterial technology, rendering Accel Lifestyle's apparel supremely comfortable, high-quality, and remarkably odor-resistant. With this cutting-edge fabric, Accel Lifestyle firmly establishes itself as a trailblazer in the industry, setting new standards for functionality and style.

As CultureMap reported in 2019, Eddings's innovative work was rewarded with a partnership with Inc. Magazine, Houston billionaire Tilman Fertitta, and others.

Amanda Cotler and Megan Eddings of Accel Lifestyle are celebrating a big win for their company. Photo courtesy

"We are beyond elated about the Accel x Talbots launch," Eddings tells CultureMap." Amanda Cotler, Accel's Director of Operations, and I have been working on this opportunity for a year, and it feels incredible for the collaboration to be live. Our passions are textiles with technology and an ethical made-in-the-USA supply chain. To have a multi-billion dollar company like Talbots care about the same things brings us so much joy."

In addition to their remarkable achievements in fashion, Accel Lifestyle champions the power of women in STEM through their team's leadership and this collaboration. By showcasing the applications of science and technology within the realm of fashion, Accel Lifestyle and Talbots are spotlighting the remarkable potential within these fields.

With the Accel Lifestyle x Talbots collaboration in full swing, customers can expect an extraordinary fusion of sustainable fashion and impeccable style. The Accel Lifestyle collaboration features an Anti-Odor Power Tank and an Anti-Odor Timeless Tee. Both are available in colors black and white.

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This article originally ran on CultureMap.

This week's Houston innovators to know include Megan Eddings and Amanda Cotler of Accel Lifestyle and Brad Burke of Rice Alliance. Photos courtesy

3 Houston innovators to know this week

Who's who

It seems like 2020 is the year of the pivot and taking what the world has thrown at you —from pandemics to oil gluts — and making something out of what you have.

This week's innovators to know include a Houston startup flipping the switch on production to make face masks to the Rice Alliance re-envisioning an annual event that usually takes place at a global conference.

Megan Eddings and Amanda Cotler of Accel Lifestyle

Photos courtesy

When Megan Eddings and Amanda Cotler saw the CDC was recommending medical professionals wear bandanas or strips of cloth when surgical face masks weren't available, they had an idea.

The duo behind Accel Lifestyle, a Houston-based athletic wear startup that has a bacteria-resistent fabric, hopped on a call to see how they could rework their supply chain to quickly pivot to making face masks.

When setting up the company, Eddings, Accel's founder, made it a priority to avoid sweatshops, and she set up her supply chain to be completely within the United States — something that's been beneficial to the company's COVID pivot.

"If we did not have a 100 percent domestic supply chain, there's no way we could have done this," Eddings says.

Eddings and Cotler joined the Houston Innovators Podcast to share the story of how Accel went from deciding to make the masks to selling them by the thousands to Houston Methodist.

"When you think of face masks, you wouldn't think about activewear or thinking of Accel being a part of the fight against coronavirus," Cotler says. However, that might no longer be the case for the company now. Click here to learn more and to stream the podcast episode.

Brad Burke, managing director of the Rice Alliance for Technology and Entrepreneurship

Photo via alliance.rice.edu

Rice Alliance for Technology and Entrepreneurship typically hosts their Energy Tech Venture Day from the one of the halls within NRG Arena at the annual Offshore Technology Conference. However, the conference that attracts thousands of people from around the world, much like so many events, was canceled due to coronavirus.

But Brad Burke and his team at the Rice Alliance turned to tech to introduce the first virtual event, which then took place on Thursday, May 7. Burke introduced the event that had 39 startups that represented 11 different states and six different countries, 13 call Houston their HQ.

"We had many startups and corporations reach out to us and ask us if we could go ahead with the event in a virtual format, so that's how we ended up where we are today," says Burke. Click here to read more.

Megan Eddings and Amanda Cotler of Accel Lifestyle join the Houston Innovators Podcast to share how they pivoted from making T-shirts to face masks. Photos courtesy

From T-shirts to facemasks, how this Houston startup quickly made its COVID-19 pivot

HOUSTON INNOVATORS PODCAST EPISODE 30

Startups across Houston have made the decision to pivot their business or technology amid the COVID-19 crisis — both to stay afloat in the shutdown and to contribute to the community.

Houston-based Accel Lifestyle, an athletic wear company that has designed a bacteria-resistant material, flipped a switch on its production to make face masks `rather than T-shirts and tanks with their Prema fabric. On the latest episode of the Houston Innovators Podcast, Megan Eddings, founder and CEO, and Amanda Cotler, director of operations, shared the story of how this pivot came to be.

"When you think of face masks, you wouldn't think about activewear or thinking of Accel being a part of the fight against coronavirus," Cotler says.

But when Cotler and Eddings saw the Center for Disease Control was recommending wearing bandanas and cloth when face masks weren't available, they had an epiphany.

"Megan and I read that and immediately hopped on a call with our team," Cotler says. "We had a realization with our antibacterial fabric that a face mask made from it would be so much cleaner."

Within 24 hours, the duo had a sample in their hands, and they had 14,000 yards of their Prema fabric being shipped from California to Houston, where they had managed to find 60 local sewers ready to start making the masks.

When setting up the company, Eddings made it a priority to avoid sweatshops, and she set up her supply chain to be completely within the United States — something that's been beneficial to the company's COVID pivot.

"If we did not have a 100 percent domestic supply chain, there's no way we could have done this," Eddings says.

Packs of 10 masks are available online, but the bulk of Accel's mask sales have been to hospitals like Houston Methodist, which has ordered thousands.

Now, with the Houston workforce making moves to return to the work place, Eddings says she's seen an increased interest in corporations wanting custom masks with the company logo on it for their employees.

Eddings and Cotler share the story of Accel and its ability to pivot amid a national crisis on the podcast. Stream the episode below or wherever you get you podcasts — just search for the Houston Innovators Podcast.


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Texas tops ranking of best state for investors in new report

by the numbers

Texas ranks third on a new list of the best states for investors and startups.

Investment platform BrokerChooser weighed five factors to come up with its ranking:

  • 2024 Google search volume for terms related to investing
  • Number of investors
  • Number of businesses receiving investments in 2024
  • Total amount of capital invested in businesses in 2024
  • Percentage change in amount of investment from 2019 to 2024

Based on those figures, provided mostly by Crunchbase, Texas sits at No. 3 on the list, behind No. 1 California and No. 2 New York.

Especially noteworthy for Texas is its investment total for 2024: more than $164.5 billion. From 2019 to 2024, the state saw a 440 percent jump in business investments, according to BrokerChooser. The same percentages are 204 percent for California and 396 percent for New York.

“There is definitely development and diversification in the American investment landscape, with impressive growth in areas that used to fly under the radar,” says Adam Nasli, head analyst at BrokerChooser.

According to Crunchbase, funding for Texas startups is off to a strong start in 2025. In the first three months of this year, venture capital investors poured nearly $2.9 billion into Lone Star State companies, Crunchbase data shows. Crunchbase attributes that healthy dollar amount to “enthusiasm around cybersecurity, defense tech, robotics, and de-extincting mammoths.”

During the first quarter of this year, roughly two-thirds of VC funding in Texas went to just five companies, says Crunchbase. Those companies are Austin-based Apptronik, Austin-based Colossal Biosciences, Dallas-based Island, Austin-based NinjaOne, and Austin-based Saronic.

Autonomous truck company rolls out driverless Houston-Dallas route

up and running

Houston is helping drive the evolution of self-driving freight trucks.

In October, Aurora opened a more than 90,000-square-foot terminal at a Fallbrook Drive logistics hub in northwest Houston to support the launch of its first “lane” for driverless trucks—a Houston-to-Dallas route on the Interstate 45 corridor. Aurora opened its Dallas-area terminal in April and the company began regular driverless customer deliveries between the two Texas cities on April 27.

Close to half of all truck freight in Texas moves along I-45 between Houston and Dallas.

“Now, we are the first company to successfully and safely operate a commercial driverless trucking service on public roads. Riding in the back seat for our inaugural trip was an honor of a lifetime – the Aurora Driver performed perfectly and it’s a moment I’ll never forget,” Chris Urmson, CEO and co-founder of Pittsburgh-based Aurora, said in a news release.

Aurora produces software that controls autonomous vehicles and is known for its flagship product, the Aurora Driver. The software is installed in Volvo and Paccar trucks, the latter of which includes brands like Kenworth and Peterbilt.

Aurora previously hauled more than 75 loads per week under the supervision of vehicle operators from Houston to Dallas and Fort Worth to El Paso for customers in its pilot project, including FedEx, Uber Freight and Werner. To date, it has completed over 1,200 miles without a driver.

The company launched its new Houston to Dallas route with customers Uber Freight and Hirschbach Motor Lines, which ran supervised commercial pilots with Aurora.

“Transforming an old school industry like trucking is never easy, but we can’t ignore the safety and efficiency benefits this technology can deliver. Autonomous trucks aren’t just going to help grow our business – they’re also going to give our drivers better lives by handling the lengthier and less desirable routes,” Richard Stocking, CEO of Hirschbach Motor Lines, added in the statement.

The company plans to expand its service to El Paso and Phoenix by the end of 2025.

“These new, autonomous semis on the I-45 corridor will efficiently move products, create jobs, and help make our roadways safer,” Gov. Greg Abbott added in the release. “Texas offers businesses the freedom to succeed, and the Aurora Driver will further spur economic growth and job creation in Texas. Together through innovation, we will build a stronger, more prosperous Texas for generations.”

In July, Aurora said it raised $820 million in capital to fuel its growth—growth that’s being accompanied by scrutiny.

In light of recent controversies surrounding self-driving vehicles, the International Brotherhood of Teamsters, whose union members include over-the-road truckers, recently sent a letter to Lt. Gov. Dan Patrick calling for a ban on autonomous vehicles in Texas.

“The Teamsters believe that a human operator is needed in every vehicle—and that goes beyond partisan politics,” the letter states. “State legislators have a solemn duty in this matter to keep dangerous autonomous vehicles off our streets and keep Texans safe. Autonomous vehicles are not ready for prime time, and we urge you to act before someone in our community gets killed.”

Houston cell therapy company launches second-phase clinical trial

fighting cancer

A Houston cell therapy company has dosed its first patient in a Phase 2 clinical trial. March Biosciences is testing the efficacy of MB-105, a CD5-targeted CAR-T cell therapy for patients with relapsed or refractory CD5-positive T-cell lymphoma.

Last year, InnovationMap reported that March Biosciences had closed its series A with a $28.4 million raise. Now, the company, co-founded by Sarah Hein, Max Mamonkin and Malcolm Brenner, is ready to enroll a total of 46 patients in its study of people with difficult-to-treat cancer.

The trial will be conducted at cancer centers around the United States, but the first dose took place locally, at The University of Texas MD Anderson Cancer Center. Dr. Swaminathan P. Iyer, a professor in the department of lymphoma/myeloma at MD Anderson, is leading the trial.

“This represents a significant milestone in advancing MB-105 as a potential treatment option for patients with T-cell lymphoma who currently face extremely limited therapeutic choices,” Hein, who serves as CEO, says. “CAR-T therapies have revolutionized the treatment of B-cell lymphomas and leukemias but have not successfully addressed the rarer T-cell lymphomas and leukemias. We are optimistic that this larger trial will further validate MB-105's potential to address the critical unmet needs of these patients and look forward to reporting our first clinical readouts.”

The Phase 1 trial showed promise for MB-105 in terms of both safety and efficacy. That means that potentially concerning side effects, including neurological events and cytokine release above grade 3, were not observed. Those results were published last year, noting lasting remissions.

In January 2025, MB-105 won an orphan drug designation from the FDA. That results in seven years of market exclusivity if the drug is approved, as well as development incentives along the way.

The trial is enrolling its single-arm, two-stage study on ClinicalTrials.gov. For patients with stubborn blood cancers, the drug is providing new hope.