3 Houston innovators to know this week

Who's who

This week's batch of innovators have had to be pretty creative in their industries. Courtesy photos

The ability to innovate lives in one's ability to think outside of the box — no matter the industry. This week's Houston innovators to know have had to get creative and think of new ways of doing things, from retailing to creating greeting cards.

Harvin Moore, president of Houston Exponential

Harvin Moore, who has a 20-year career in tech and innovation, has been named as president of Houston Exponential. Courtesy of HX

Harvin Moore has been a banker, an educator, an elected official, and more — but his newest title is president of Houston Exponential, which suits him just fine.

Now, under his new role, he's leading the nonprofit that's focused on connecting, promoting, and attracting within Houston's innovation ecosystem.

"There's no question that five years from now, or 10 years from now, Houston will be a very large and continually rapidly growing tech economy," Moore tells InnovationMap. "The question is just how fast it is going to get here." Read more.

Alex Kurkowski, founder of Tellinga

Alex Kurkowski wanted to tell a better story. Courtesy of Tellinga

Alex Kurkowski has a problem with traditional greeting cards.

"They're templated. They're frozen, stagnant, fixed in what they are," Kurkowski says. "They suck."

The Rice University MBA grad decided he would do something about it. He created his business, Tellinga — short for "telling a story" — to create a new avenue for people to communicate a message to their loved ones. Kurkowski has big plans for his company and the platform he's creating. Read more.

Steve Scala, executive vice president of corporate development for DiCentral

Steve Scala joined DiCentral in 2014 to focus on growing the company worldwide. Courtesy of DiCentral

Something's brewing in retail — and it's scaring the industry. Steve Scala writes in a guest column for InnovationMap that dropshipping — the process of shipping products direct from vendors to customers, cutting out warehouses and storage facilities — is only going to gain traction in the industry.

"The study found that approximately 88 percent of retailers see dropship as inevitable to long-term success," Scala writes. "According to 87 percent of those retailers surveyed also experienced an increase in revenue as a result of dropshipping. Customer service also benefitted from dropship, with 84 percent of retailers noting improvements to customer service after adopting the dropshipping fulfillment model." Read more.

Tellinga creates artistic and personal cards for every occasion. Courtesy of Tellinga

Houston entrepreneur has big plans for his art-driven, storytelling card company

bringing snail mail back

Alex Kurkowski can't count how many times he's gone looking for a greeting card — before some holiday, birthday, or special occasion — and found nothing that suited his recipient. He doesn't remember when he started editing them, either. For a few years now, he's been taking markers and pens to the greeting cards, blacking out words and scribbling new ones to say what he wanted to.

"They're templated. They're frozen, stagnant, fixed in what they are," Kurkowski says. "They suck."

But he can remember a few moments that changed that for him — and for Houston. When he started sending his family cards he'd sketched that depicted scenes from their lives, his classmates in the Rice University MBA program told him that, despite his pharmaceuticals background, this might actually be the right business for him.

Tellinga is hardly just a maker of greeting cards; it's in the business of storytelling, and customers can have personalized artworks delivered right to their mailboxes — a site for reclaiming, Kurkowski says, from the dread of bills and marketing materials.

"I'm trying to tap back into the tangible, physical and real side of life," Kurkowski says.

A year ago, Kurkowski sent his first Tellingas — short for "Telling a Story" — as an official business. He made the initial cards himself, but soon couldn't meet the demand on his own. Today, Tellingas are crafted from a cohort of more than 20 artists who are mostly Houston-based and, as Kurkowski says, make his work look like garbage.

Customers can select a few purchase options for customers, ranging from a one-panel story to 12 scenes. They upload a photo of the people they want drawn and submit their idea for the artwork on the website — they can create renderings of real-life events they want to remember or they might tell a wacky, fantasy story. For Kurkowski, the most important part is receiving the art over time — for example, the 12-panel pieces are sent over a one-month period.

Currently, Tellinga's only full-time staff is Kurkowski, but he's looking to hire a CTO to manage the growing demands of the website, where orders are placed. He also wants Tellinga to grow into the Airbnb model, with artists posting their works on his site and setting the price of their commissions themselves. Kurkoswki will be raising funds in the next investment round.

Until then, he's hoping to grow Tellinga's ability to turn stories into keepsakes — by offering ways to frame and preserve them, and by introducing a subscription model, so that customers can select days from of an entire calendar year to send their personalized artworks—constantly tapping back into that physical side of life like Kurkowsi wants.

"It's just cool because it's different," Kurkowski says. "It's getting away from the digital media world."

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

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