3 Houston innovators to know this week

Who's Who

From a former astronaut to growing software company leaders, here are three innovators to know. Courtesy photos

This week's set of innovators to know are familiar with pivoting careers. All three had successful careers — from energy finance to space exploration — before jumping into a new field. And each set of prior experience prepared them for what they are doing today.

Alex Colosivschi, founder and CEO of Currux

Courtesy of Currux

Alex Colosivschi had a successful career in energy finance before he started his company, Currux. He was walking in his Rice Village neighborhood when the idea came to him. He realized that despite the green surroundings, he was choked by the smell of engine exhaust.

"I started with thinking about the future of energy and how the industry will adapt to a world of electric, autonomous and shared mobility, and the need to reduce CO2 emissions," he says.

Tim Kopra, partner at Blue Bear Capital

Courtesy of Blue Bear Capital

It might not be easy to connect the dots between Tim Kopra's NASA career and his current role at Blue Bear Capital, but for Kopra, it makes perfect sense.

"On face value, it may sound like an odd match, taking someone with a tech and operational background and putting them in venture, but quite frankly it feels very familiar to me because my career has really been focused on working on complex technology and operations with very small teams," Kopra says. "It's not just a theoretical understanding of the technology, but understanding how to use the technology and how it works."

Stuart Morstead, co-founder and COO of Arundo Analytics

Courtesy of Arundo Analytics

Stuart Morstead spent the bulk of his career in consulting, so he knows the importance of understanding the needs an industry has. He co-founded Arundo Analytics to address the analytical needs energy companies have on a regular basis.

Morstead says that most industrial companies that encounter issues with operations such as equipment maintenance "lack the data science and software capabilities to drive value from insights into their daily operations."

Arundo is growing — both from a funding standpoint as well as through its staff. The Houston company has big plans for its 2019.

This entrepreneur says the future of driving is using smart tech on a subscription-based business model. Pexels

This company’s machine learning programs are making driving in Houston safer — and cheaper

Vroom, Vroom

Two thousand years ago, in ancient Rome, the primary mode of transportation was an intelligent one: the horse. The Latin word "currus" was the inspiration for Alex Colosivschi when it came to naming his business, Currux.

"We chose this name because we believe in a future where cars and actually most modes of transportation will be intelligent, like horses," he explains. "And so it's a great name considering our focus on the future of mobility and machine learning."

The change from "s" to "x" at the end of the word allowed Colosivschi to trademark the name.

The entrepreneur, whose career was focused on energy finance until starting the new company in 2017, came up with the idea for Currux while walking in his Rice Village neighborhood. He realized that despite the green surroundings, he was choked by the smell of engine exhaust.

"I started with thinking about the future of energy and how the industry will adapt to a world of electric, autonomous and shared mobility, and the need to reduce CO2 emissions," he says.

His goal is an ambitious one: With Currux, Colosivschi hopes to not only reduce the cost and carbon footprint of owning a car, but also the accident rates. How? Currux itself is a long-term automobile subscription service. Colosivschi says to think of it as a long-term rental or a more flexible version of a lease. The car is delivered through an app and there is no commitment at the end of the subscription. Regular maintenance is included and the company is on the way to providing insurance, too.

It's also possible to share a car or fleet of cars with friends, assuring that your vehicle is only touched by people you know. This will be even more true when autonomous driving technology allows the car to go from subscriber to subscriber without a human in between.

"With the advent of digital shopping, we believe subscriptions will become the primary way that people get a car," Colosivschi predicts.

This will save clients money, but the ultimate goal is much bigger. Colosivschi wants to reduce air pollution. This will happen naturally with having fewer, mostly electric, cars on the road thanks to vehicle sharing, but another technology will also aid in the fight.

Currux Vision, which closely followed Currux in development, is a smartphone-based driver assistance program. It will help lower fuel consumption and reduce accident rates by "proactively coaching the driver on best driving practices," says Colosivschi.

"Just by slowing down and driving in a less aggressive manner, we can significantly reduce fuel consumption and more importantly prevent accidents from happening."

If you've driven or ridden in a Tesla, you've seen similar technology in action. Computer vision creates accident warnings and tracks how you handle your vehicle on the road. Yep, it's AI for your phone, which also incorporates GPS tracking, navigation and driver profile scoring.

"This set of functionalities normally require three or four different types of hardware and software systems and many thousands of dollars in expense per each car," explains Colosivschi.

But Currux Vision only requires that the user install the app, have a car-mounted phone holder with an unobstructed view of the road, and pay $4.99 each month for the technology.

Both these apps were created by Currux's own technical team, based mostly in Ukraine. As the company expands, Colosivschi has plans to significantly grow the Galleria-area Houston team, which is currently just a few employees strong.

But Colosivschi is ready for big growth. Currently, Currux is available only in Houston, but other U.S. cities will follow soon. As an energy industry lifer, the entrepreneur is also primed for significant changes not only to how we drive, but how we consume energy.

"The age of the internal combustion engine and automobile ushered in the age of oil. The age of lithium ion batteries, machine learning and digitization of transaction mediums similarly will have profound effects for both transportation and energy sectors," he predicts. He's confident that Currux can grow with those sea changes. And he's ready to help transform the world, starting with Houston.

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Houston-area lab grows with focus on mobile diagnostics and predictive medicine

mobile medicine

When it comes to healthcare, access can be a matter of life and death. And for patients in skilled nursing facilities, assisted living or even their own homes, the ability to get timely diagnostic testing is not just a convenience, it’s a necessity.

That’s the problem Principle Health Systems (PHS) set out to solve.

Founded in 2016 in Clear Lake, Texas, PHS began as a conventional laboratory but quickly pivoted to mobile diagnostics, offering everything from core blood work and genetic testing to advanced imaging like ultrasounds, echocardiograms, and X-rays.

“We were approached by a group in a local skilled nursing facility to provide services, and we determined pretty quickly there was a massive need in this area,” says James Dieter, founder, chairman and CEO of PHS. “Turnaround time is imperative. These facilities have an incredibly sick population, and of course, they lack mobility to get the care that they need.”

What makes PHS unique is not only what they do, but where they do it. While they operate one of the largest labs serving skilled nursing facilities in the state, their mobile teams go wherever patients are, whether that’s a nursing home, a private residence or even a correctional facility.

Diagnostics, Dieter says, are at the heart of medical decision-making.

“Seventy to 80 percent of all medical decisions are made from diagnostic results in lab and imaging,” he says. “The diagnostic drives the doctor’s or the provider’s next move. When we recognized a massive slowdown in lab results, we had to innovate to do it faster.”

Innovation at PHS isn’t just about speed; it’s about accessibility and precision.

Chris Light, COO, explains: “For stat testing, we use bedside point-of-care instruments. Our phlebotomists take those into the facilities, test at the bedside, and get results within minutes, rather than waiting days for results to come back from a core lab.”

Scaling a mobile operation across multiple states isn’t simple, but PHS has expanded into nine states, including Texas, Oklahoma, Kansas, Missouri and Arizona. Their model relies on licensed mobile phlebotomists, X-ray technologists and sonographers, all trained to provide high-level care outside traditional hospital settings.

The financial impact for patients is significant. Instead of ambulance rides and ER visits costing thousands, PHS services often cost just a fraction, sometimes only tens or hundreds of dollars.

“Traditionally, without mobile diagnostics, the patient would be loaded into a transportation vehicle, typically an ambulance, and taken to a hospital,” Dieter says. “Our approach is a fraction of the cost but brings care directly to the patients.”

The company has also embraced predictive and personalized medicine, offering genetic tests that guide medication decisions and laboratory tests that predict cognitive decline from conditions like Alzheimer's and Parkinson’s.

“We actively look for complementary services to improve patient outcomes,” Dieter says. “Precision medicine and predictive testing have been a great value-add for our providers.”

Looking to the future, PHS sees mobile healthcare as part of a larger trend toward home-based care.

“There’s an aging population that still lives at home with caretakers,” Dieter explains. “We go into the home every day, whether it’s an apartment, a standalone home, or assisted living. The goal is to meet patients where they are and reduce the need for hospitalization.”

Light highlighted another layer of innovation: predictive guidance.

“We host a lot of data, and labs and imaging drive most treatment decisions,” Light says. “We’re exploring how to deploy diagnostics immediately based on results, eliminating hours of delay and keeping patients healthier longer.”

Ultimately, innovation at PHS isn’t just about technology; it’s about equity.

“There’s an 11-year life expectancy gap between major metro areas and rural Texas,” Dieter says. “Our innovation has been leveling the field, so everyone has access to high-quality diagnostics and care, regardless of where they live.”

Aegis Aerospace appoints Houston space leader as new president

moving up

Houston-based Aegis Aerospace's current chief strategy officer, Matt Ondler, will take on the additional role of president on Jan. 1. Ondler will succeed Bill Hollister, who is retiring.

“Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers,” Stephanie Murphy, CEO of Aegis Aerospace, said in a news release.

Hollister guided Aegis Aerospace through expansion and innovation in his three years as president, and will continue to serve in the role of chief technology officer (CTO) for six months and focus on the company's technical and intellectual property frameworks.

"Bill has played an instrumental role in shaping the success and growth of our company, and his contributions leave an indelible mark on both our culture and our achievements," Murphy said in a news release.

Ondler has a background in space hardware development and strategic leadership in government and commercial sectors. Ondler founded subsea robots and software company Houston Mechatronics, Inc., now known as Nauticus Robotics, and also served as president, CTO and CSO during a five-year tenure at Axiom Space. He held various roles in his 25 years at NASA and was also named to the Texas Aerospace Research and Space Economy Consortium Executive Committee last year.

"I am confident that with Matt at the helm as president and Bill supporting us as CTO, we will continue to build on our strong foundation and further elevate our impact in the space industry," Murphy said in a news release. "Matt's vision, experience, and understanding of our evolving markets position us to build on our foundation and pursue new frontiers."

Rice University launches new center to study roots of Alzheimer’s and Parkinson’s

neuro research

Rice University launched its new Amyloid Mechanism and Disease Center last month, which aims to uncover the molecular origins of Alzheimer’s, Parkinson’s and other amyloid-related diseases.

The center will bring together Rice faculty in chemistry, biophysics, cell biology and biochemistry to study how protein aggregates called amyloids form, spread and harm brain cells. It will serve as the neuroscience branch of the Rice Brain Institute, which was also recently established.

The team will work to ultimately increase its understanding of amyloid processes and will collaborate with the Texas Medical Center to turn lab discoveries into real progress for patients. It will hold its launch event on Jan. 21, 2026, and hopes to eventually be a launchpad for future external research funding.

The new hub will be led by Pernilla Wittung-Stafshed, a Rice biophysicist and the Charles W. Duncan Jr.-Welch Chair in Chemistry.

“To make a real difference, we have to go all the way and find a cure,” Wittung-Stafshede said in a news release. “At Rice, with the Amyloid Mechanism and Disease Center as a catalyst, we have the people and ideas to open new doors toward solutions.”

Wittung-Stafshede, who was recruited to Rice through a Cancer Prevention and Research Institute of Texas grant this summer, has led pioneering work on how metal-binding proteins impact neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. Her most recent study, published in Advanced Science, suggests a new way of understanding how amyloids may harm cells and consume the brain’s energy molecule, ATP.

According to Alzheimer’s Disease International, neurodegenerative disease cases could reach around 78 million by 2030 and 139 million by 2050. Wittung-Stafshede’s father died of dementia several years ago.

“This is close to my heart,” Wittung-Stafshede added in the news release. “Neurodegenerative diseases such as dementia, Alzheimer’s and Parkinson’s are on the rise as people live longer, and age is the largest risk factor. It affects everyone.”
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