These three innovators to know are responsible for solving problems here in Houston. Courtesy photos

A good innovator sees a need and fills it. Whether it's a bigger budget for new hospital technology, a network for female software developers in Houston, or access to creatives for nonprofits, these three Houston innovators are responsible for filling the needs of Houston's innovation ecosystem.

Roberta Schwartz, chief innovation officer of Houston Methodist

Roberta Schwartz is leading the innovation initiative at Houston Methodist. Courtesy of Houston Methodist

Houston Methodist has always been an innovative hospital system, says Roberta Schwartz, chief innovation officer, so it was not really that surprising that a group of hospital officials had an interest in new technologies.

"As we watched these technologies come in, we found that there were a number of us within the organization that were just talking about it all the time and watching how we could really revolutionize the way we worked by embracing these new technologies," Schwartz says.

The group named itself the "digital innovation obsessed people," however, now that group calls itself the Houston Methodist Center for Innovation, and Schwartz is leading the initiative. Read more about Schwartz and the new center here. 

Alex Anderson, founder of Good Measure

Alex Anderson started Good Measure to help nonprofits have access to creatives and storytelling tools. Courtesy of Alex Anderson

Houston-based nonprofit, Good Measure, completed its third creative workshop last week — and its first outside of Houston. Nuu Group's Alex Anderson and Tres Garner founded Good Measure to help nonprofits with storytelling and media, and they took their efforts to New York City to work with Memphis-based youth violence nonprofit, Grounded.

Just like the last Good Measure project, volunteer creatives has less than 72 hours to create a slew of branding materials, including user experience-focused designs, web pages, photos, videos, and more for the nonprofit.

"My hope is that each and every individual who attended sees the impact that our craft skills can make," Anderson wrote in a post on Medium. "We certainly can volunteer our time and work with nonprofits, but the real question is whether we can return to our day jobs, to clients with big budgets and capitalistic mindsets, and influence their decisions—to push them from opportunistic to purposeful."

Silver Ehiwario, director of Women Who Code Houston Chapter

Silver Ehiwario flipped careers a while back, and now she hopes to help other women with that process. Courtesy of Silver Ehiwario

Making a career switch is never easy — but it's extremely hard for women trying to enter the technology industry. Women Who Code, a global organization, just opened up shop in Houston, thanks to seven female directors, including Silver Ehiwario, who changed her career to tech recently.

"We are able to see a lot of people are changing their careers from what they have done before — just like I changed mine," she says. "We need communities where they can be inspired." Read more about Ehiwario and Women Who Code here.

Allison Williams, who has been working with the Transformational Prison Project for two years, attended Good Measure to consult on the brand development. Alan Nguyen/Good Measure

Houston creatives relaunch nonprofit's brand through a 3-day collaboration

For good measure

What if you could harness the power of a city's top creative professionals to create a brand identity for a nonprofit that otherwise couldn't afford it? Alex Anderson posed that question to some of his colleagues, and Good Measure was born.

"Good Measure exists to broaden the conversation about good in the world and what that means and how people can contribute to good no matter their skill set," says Anderson, who is a senior brand strategist and account manager at Houston-based NUU Group.

Good Measure is a Houston-based nonprofit that hosts three-day creative collaborations with local designers, writers, brand strategists, and more. The goal is simple: Equip a nonprofit with new storytelling tools — like a website, social media, and video communicating the organization's message.

This weekend was the second event Anderson organized with his co-founder, Tres Garner. The nonprofit partner was the Transformational Prison Project, which uses restorative justice in Massachusetts prisons to help incarcerated individuals mindfully use their time in prison to create healing. It's about bringing everyone involved in the criminal justice system to the table to thoughtfully effect change and reinstate humanity in these prisons.

"The Transformational Prison Project understands that no matter what your position is within the criminal justice system that everybody is vulnerable to trauma. So, it's in everyone's vested interest to create more of a system that's reparative and healing than punitive." says Karen Lischinsky, director of TPP, in the teaser video created at Good Measure.

Lischinsky was a vital part of the weekend, as was actress Allison Williams (Girls and Get Out), who has been an advocate for TPP and has led restorative justice sessions in Massachusetts prisons for two years.

"I wish to transform the way that prisons, as we imagine them today, operate and the effects that they have on people," Williams says in the video.

Using their powers for good
Good Measure brought together 40 creatives — designers, developers, strategists, videographers, photographers, writers, stylists, and more — into NUU Group's East Downtown office to develop new branding, web design, and videography for TPP. Filming took place down the street at Primer Grey. Anderson says the point is to break down barriers and bring together individuals who would otherwise not get to work together.

"It's some feedback that we've heard over and over again how refreshing and inspiring it is to work with people across the city," Anderson says. "So, you get to come together and learn each other's processes and have a case study or portfolio piece with someone who's work you admire."

Good Measure volunteers work alongside the nonprofit partners, so Lischinsky and Williams were there every step of the way. It was a learning process for both sides of the equation — the volunteers making sure they understand and express the TPP's mission as well as TPP learning the importance of the brand development process. Anderson says Lischinsky's presence was key to the success of the weekend — as was Williams' who wasn't just a celebrity endorsement. Anderson says he could see her full heart was committed to the program.

"You pull in a celebrity figure, and there's a tactical play. It's advertising," he says. "But what was different about this event is that Allison is not a face. She showed up from the first day of Good Measure to participate and contribute as someone who is on the board of TPP and an advocate for the program."

Creating a movement
Good Measure is planning to double down on its efforts for a New York weekend early next year to serve two nonprofits with 100 creatives volunteering. The organization also expects to return to do another Houston weekend in 2019 as well as a collaboration in Los Angeles.

Anderson says they also plan on hosting a one-day conference in Houston to discuss social good. Williams and Lischinsky are both onboard to attend.

Doing the homework

Alan Nguyen/Good Measure 

Actress Allison Williams and TPP Director Karen Lischinsky kicked off the three-day rebranding collaboration with a discussion focused on the organization's goals, challenges, and messaging.

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Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

     
  • $1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
  • $922 million for the University of Houston System
  • $167 million for Texas Southern University
  • $10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

     
  • Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
  • Created the Lake Houston Dredging and Maintenance District
  • Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.