Here are the eight companies currently being accelerated by Texas Medical Center Innovation. Photo courtesy of TMC

The Texas Medical Center Innovation has named its new cohort of health tech companies it's currently accelerating.

This first batch of companies for 2024 was selected from last fall's TMC Bootcamp. Eight of the 10 startups from the bootcamp have moved on to the Accelerator for HealthTech.

"Hailing from diverse corners of the globe—from the tech corridors of Texas and California to Ireland and Australia—these companies converge with a shared mission—to move healthcare forward," Devin Dunn, head of the Accelerator for Health Tech, writes in a TMC blog post. "Through personalized mentorship and guidance, these eight companies are able to navigate complex challenges and refine their strategies, while leveraging the expertise of Texas Medical Center ecosystem to validate their innovations and drive real-world impact."

The selected companies include:

  • AcorAI, from Stockholm, Sweden, which is developing a first-of-its-kind, hand-held, scalable medical device for non-invasive intracardiac pressure monitoring to improve heart failure management for more than 64 million patients worldwide.
  • AirSeal, based in St. Louis, Missouri, which has developed a novel serum-based biomarker technology – circulating fatty acid synthase (cFAS) – that can diagnose cardiovascular and peripheral artery disease with high accuracy in both women and men.
  • Foxo, headquartered in Brisbane, Australia, serves as an interoperable tool designed to enhance clinical collaboration across the healthcare ecosystem. It enables secure, two-way communication with features such as video, voice, screen share, file sharing, and real-time messaging.
  • San Francisco-based Knowtex, an artificial intelligence-powered software writes medical documentation for you and assigns correct codes to ensure proper reimbursement.
  • NeuroBell, from Cork, Ireland, which is working on a novel medical device providing portable EEG monitoring with real-time and automated neonatal seizure alerts at the bedside.
  • Perth, Australia-based OncoRes Medical that's developing an intraoperative imaging technology to provide surgeons with real-time assessment of tissue microstructure.
  • From right here in Houston, Steradian Technologies, which has created RUMI, the first noninvasive, fully portable infectious disease diagnostic that costs the price of a latte. It uses novel photon-based detection to collect and diagnose infectious diseases in breath within 30 seconds.
  • TYBR, also based in Houston, created a flowable extracellular matrix hydrogel, crafted to safeguard healing tendons and ligaments from scarring and adhesions. The company originated from the TMCi’s Biodesign fellowship and now has entered into the Accelerator for HealthTech to sharpen its regulatory strategy, particularly in anticipation of FDA conversations.

Applications for the next Accelerator for HealthTech will open in May of this year.

Meet the latest global health tech startups to get an invite to Houston from TMC Innovation. Photo via tmc.edu

TMC names latest cohort of health tech startups for upcoming bootcamp

headed to Houston

The Texas Medical Center's innovation arm has again invited a set of health tech startups to mix and mingle with potential partners, investors, and customers in hopes to score a place in the HealthTech Accelerator.

For the 17th time, the TMC Innovation Factory is hosting its HealthTech Accelerator — starting first with announcing its bootcamp cohort, a process that includes bringing all 10 companies to Houston for valuable networking. A selection of the bootcamp will be invited into the full accelerator that will run into next spring.

The 10 selected companies with solutions from heart failure to chronic respiratory disease and more, according to TMC, include:

  • Acorai, from Stockholm, Sweden, which is developing a first-of-its-kind, hand-held, scalable medical device for non-invasive intracardiac pressure monitoring to improve heart failure management for more than 64 million patients worldwide.
  • Singapore-based Aevice Health, a connected care platform powered by the world’s smallest smart wearable stethoscope to support chronic respiratory disease patients through their continuum of care.
  • AirSeal, based in St. Louis, Missouri, which has developed a novel serum-based biomarker technology – circulating fatty acid synthase (cFAS) – that can diagnose cardiovascular and peripheral artery disease with high accuracy in both women and men.
  • Candlelit Care, a Charlotte, North Carolina-based point-of-care digital platform focused on the prevention of perinatal mental and anxiety disorders (PMADs) among Black women and birthing parents.
  • San Francisco-based Knowtex, an artificial intelligence-powered software writes medical documentation for you and assigns correct codes to ensure proper reimbursement.
  • NeuroBell, from Cork, Ireland, which is working on a novel medical device providing portable EEG monitoring with real-time and automated neonatal seizure alerts at the bedside.
  • Perth, Australia-based OncoRes Medical that's developing an intraoperative imaging technology to provide surgeons with real-time assessment of tissue microstructure.
  • From right here in Houston, Steradian Technologies, which has created RUMI, the first noninvasive, fully portable infectious disease diagnostic that costs the price of a latte. It uses novel photon-based detection to collect and diagnose infectious diseases in breath within 30 seconds.
  • Foxo, headquartered in Brisbane, Australia, serves as an interoperable tool designed to enhance clinical collaboration across the healthcare ecosystem. It enables secure, two-way communication with features such as video, voice, screen share, file sharing, and real-time messaging.
  • Thrive Health’s, from Vancouver, Canada, is a platform is a low-code framework for designing and delivering patient engagement solutions. Create tools that enable partners to close healthcare gaps quickly, strengthen care relationships, and improve patient experience and outcomes.

TMC Innovation's last bootcamp cohort was announced in May. The organization also recently named 16 digital health and medical device startups from the United Kingdom to a new accelerator formed in partnership with Innovate UK.

Earlier this fall, TMC formed a strategic partnership, or BioBridge, with the Netherlands.

Seventeen of the RBPC student teams walked away with investment prizes this year. Photo courtesy of Rice

Houston student startup competition doles out record-breaking more than $3M in prizes

show me the money

Over the weekend, Houston hosted what is known as the world’s largest and richest intercollegiate student startup competition, and a Texas team took the overall win and over $3 million in investment prizes were given out at the annual banquet.

The 2023 Rice Business Plan Competition was held May 11-13 and included mentoring, pitching, and networking for the 42 student teams with over 350 judges before culminating in over 80 prizes being announced. The $3.4 million in investment and in-kind prizes marks the largest yet for the 23-year-old competition.

"Judges told us that the quality of the startups at this year’s competition was the best ever,” says Catherine Santamaria, director of the RBPC, in the news release. “One judge went so far as to say that every startup this year was worthy of investment.”

Over 450 startups applied to the competition, and the 42 startups selected hailed from 35 universities from five countries. There were five categories: energy, clean tech and sustainability; life sciences and health care solutions; consumer products and services; hard tech; and digital enterprise. Based on the judges scores, seven startups reached the finals, and this year, three Texas teams made the finals, with two being from Rice University.

All 42 companies were eligible for investment or in-kind prizes, and, even though $1.75 million in prizes was expected to be awarded, some of this year's investors doubled — or even tripled — down on investment awards. While the finalists walked away with various in-kind prizes too, here's a round up of the investment prizes each startup won at the awards.

Zaymo, Brigham Young University — $885,000

Zaymo, a tool for e-commerce brands that embeds the shopping experience within customers’ email, won the most amount of money at the awards ceremony. The company won third place and a $50,000 Investment Prize sponsored by David Anderson, Jon Finger, Anderson Family Fund, Finger Interests, Greg Novak and Tracy Druce. Zaymo also won the following awards:

  • $200,000 OWL Investment Prize
  • $100,000 Houston Angel Network Investment Prize
  • $500,000 Softeq Venture Fund Prize
  • $15,000 Eagle Investors Prize
  • $20,000 Novak Druce Carroll Investment Prize

Boston Quantum, Massachusetts Institute of Technology — $455,000

Boston Quantum, which is using enterprise quantum computing software to disrupt the financial industry, won the second-most amount of investment prizes and sixth place in the competition.

  • $5,000 Chevron Technology Ventures Sixth-Place Cash Prize
  • $300,000 OWL Investment Prize
  • $125,000 Softeq Venture Fund Prize
  • $25,000 Urban Capital Network Diversity Investment Prize in partnership with South Loop Ventures

FluxWorks, Texas A&M University — $350,000

Based on the judges scores, the big winner was FluxWorks, a Texas company that's technology includes magnetic gears that are four times quieter than standard with 99 percent efficiency and can offer unprecedented reliability from outer space to under the sea and even inside the human body. The company won the $350,000 GOOSE Capital Investment Grand Prize.

Skali, Northwestern University — $300,000

Skali, which didn't make it into the prestigious finalist positions, still walked away with $300,000 courtesy of the Softeq Venture Fund Prize. Skali's technology aims to better equip flights with medical emergency assistance.

TierraClimate, Rice University — $280,000

TierraClimate, a marketplace for selling verified carbon offsets to corporate buyers, won fourth place and the Norton Rose Fulbright $5,000 Prize. The company also won a $200,000 Softeq Venture Fund Prize and the $75,000 OWL Investment Prize.

AirSeal, Washington University in St. Louis — $250,000

Another non-finalist that still scored big was AirSeal, a company that's created a simple blood test for cardiovascular diagnostics. The startup secured the $250,000 TMC Innovation Healthcare Investment Prize.

Sygne Solutions, Rice University — $200,000

Sygne Solutions, a startup on a mission of eliminating a group of chemicals known as PFAS in water through its patent-pending technology, won second place and the $100,000 Investment Prize, sponsored by David Anderson, Jon Finger, Anderson Family Fund, Finger Interests, Greg Novak and Tracy Druce. The company also received the $100,000 TiE Houston Angels Investment Prize.

BlueVerse, Texas Tech University — $145,000

BlueVerse, a startup with tech to merge social media with reviews and rewards for small businesses, didn't make the finals but walked away with on of the $125,000 Softeq Venture Fund Prizes and the $20,000 Novak Druce Carroll Investment Prize.

Atma Leather, Yale University —$130,000

Atma Leather, a material innovation company that's created plant-based leather from banana stems and other crop waste, came in fifth place and secured the $5,000 EY Fifth-Place Cash Prize. The startup also won:

  • $75,000 OWL Investment Prizes
  • $50,000 nCourage Investment Group’s Courageous Women Entrepreneurs Investment Prize

MyLÚA Health, Cornell University — $30,000

MyLÚA Health's AI technology supports the maternal health industry. The company won the $30,000 Pearland Economic Development Corporation Spirit of Entrepreneurship Prize.

Active Surfaces, Massachusetts Institute of Technology — $25,000

With its flexible and lightweight solar panel technology, Active Surfaces scored the $25,000 New Climate Ventures Sustainability Investment Prize.

Integrated Molecular Innovations, Michigan Technological University — $25,000

Integrated Molecular Innovations, which created a wearable device that can monitor hormone levels, won the $25,000 Southwest National Pediatric Device Consortium Prize.

MiraHeart, Johns Hopkins University — $25,000

MiraHeart, which created a non-invasive way of monitoring child heart conditions, also won the $25,000 Southwest National Pediatric Device Consortium Prize.

Biome Future, University of Florida — $20,000

Biome Future, which creates ocean-safe chemicals via microbes in corals, won one of the $20,000 Novak Druce Carroll Investment Prizes.

Citrimer, University of Michigan — $10,000

A sustainable materials company, Citrimer won the $10,000 NABACO RBPC Alumni Network Prize.

Thryft Ship, University of Georgia — $10,000

Thryft Ship, which streamlines the shipping process for social media sellers, won a $10,000 nCourage Investment Group’s Courageous Women Entrepreneurs Investment Prize.

Pathways, Harvard University  — $5,000

Pathways, which is developing a full-stack sustainability platform for the construction industry, won $5,000 Shell Ventures Seventh-Place Cash Prize.

In addition to these investment prizes, the startups have the chance to score in-kind prizes. This year, that included:

  • $6,667 Baker Botts Legal Services In-Kind Prize to FluxWorks, Texas A&M University
  • $6,667 Baker Botts Legal Services In-Kind Prize to Sygne Solutions, Rice University
  • $6,667 Baker Botts Legal Services In-Kind PrizeFluxWorks to Zaymo, Brigham Young University
  • $10,000 New York Technology Capital CFO Consulting In-Kind to FluxWorks, Texas A&M University
  • EFN Mentoring Services to all startup competitors
  • Amazon Web Services to all startup competitors
  • Stage 2 Competition Entry to Sygne Solutions, Rice University
All 42 of the RBPC companies wins at least $950. In each of the three semi-final rounds, third place wins $2,000, fourth place wins $1,750, and fifth place wins $1,500. The wild card round, which acts as a second-chance competition for the companies that didn't originally make it to the finals, advances the wild card winner into the finals and also awards second place $1,000, third place $975, fourth place $950, and fifth place $950.
Here's what student teams from around the world were invited to compete in the Rice Business Plan Competition. Photo via rice.edu

Annual student startup competition in Houston names teams for 2023

getting pitch perfect

Rice Alliance for Technology and Entrepreneurship has named the 42 student startup teams that were extended invitations to compete in the 23rd annual Rice Business Plan Competition

The 2023 startup competition will take place on Rice University campus May 11 to 13, and the teams representing 37 universities from six countries will pitch to investors, mentors, and other industry leaders for the chance to win funding and prizes. Last year's RBPC doled out nearly $2 million in investment prizes.

This year, Rice saw its largest number of student startups applying for the RBPC internal qualifier from within campus. The university selected three to move on to compete at RBPC in May — Sygne Solutions, Neurnano Therapeutics, and Tierra Climate, which also received a total of $5,000 in cash prizes to these top three teams.

The 2023 RBPC will focus on five categories: energy, cleantech and sustainability; life science and health care solutions; consumer products and services; hard tech; and digital enterprise.

This invited companies, if they attend, will join the ranks of the 784 teams that previously competed in RBPC and have raised more than $4.6 billion in capital, as well as seen more than 50 successful exits including five IPOs.

The 2023 Rice Business Plan Competition invitees, according to Rice University's news release:

  • Active Surfaces, Massachusetts Institute of Technology
  • Adrigo Insights, Saint Mary’s University (Canada)
  • AirSeal, Washington University in St. Louis
  • Algbio, Yeditepe University (Turkey)
  • Arch Pet Food, University of Chicago
  • Astria Biosciences, University of Pittsburgh
  • Atma Leather, Yale University
  • Atop, UCLA
  • Biome Future, University of Florida
  • BioSens8, Boston University
  • BlueVerse, Texas Tech University
  • Boardible, Northwestern University
  • Boston Quantum, Massachusetts Institute of Technology
  • ceres plant protein cereal, Tulane University
  • Citrimer, University of Michigan
  • Dart Bioscience, University of Oxford (United Kingdom)
  • DetoXyFi, Harvard University
  • E-Sentience, Duke University
  • Edulis Therapeutics, Carnegie Mellon University
  • FluxWorks, Texas A&M University
  • Integrated Molecular Innovations, Michigan Technological University
  • Inzipio, RWTH Aachen University (Germany)
  • LoopX AI, University of Waterloo (Canada)
  • Magnify Biosciences, Carnegie Mellon University
  • MiraHeart, Johns Hopkins University
  • MyLÚA, Cornell University
  • Outmore Living, University of Texas
  • Pathways, Harvard University
  • Pediatrica Therapeutics, University of Arkansas
  • Perseus Materials, Stanford University
  • Pike Robotics, University of Texas
  • Quantanx, Arizona State University
  • Sheza, San Diego State University
  • Skali, Northwestern University
  • Sundial Solar Components, University of Utah
  • Thryft Ship, University of Georgia
  • Tierra Climate, Rice University
  • TrashTrap Sustainability Solutions, Visvesvaraya Technological University (India)
  • Unchained, North Carolina A&T State University
  • Unsmudgeable, Babson College
  • Vivicaly, University of Pennsylvania
  • Zaymo, Brigham Young University
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Houston doctor aims to revolutionize hearing aid industry with tiny implant

small but mighty

“What is the future of hearing aids?” That’s the question that led to a potential revolution.

“The current hearing aid market and technology is old, and there are little incremental improvements, but really no significant, radical new ideas, and I like to challenge the status quo,” says Dr. Ron Moses, an ENT specialist and surgeon at Houston Methodist.

Moses is the creator of NanoEar, which he calls “the world’s smallest hearing aid.” NanoEar is an implantable device that combines the invisibility of a micro-sized tympanostomy tube with more power—and a superior hearing experience—than the best behind-the-ear hearing aid.

“You put the NanoEar inside of the eardrum in an in-office procedure that takes literally five minutes,” Moses says.

As Moses explains, because of how the human cochlea is formed, its nerves break down over time. It’s simply an inevitability that if we live long enough, we will need hearing aids.

“The question is, ‘Are we going to all be satisfied with what exists?’” he asks.

Moses says that currently, only about 20 percent of patients who need hearing aids have them. That’s because of the combination of the stigma, the expense, and the hassle and discomfort associated with the hearing aids currently available on the market. That leaves 80 percent untapped among a population of 466 million people with hearing impairment, and more to come as our population ages. In a nearly $7 billion global market, that additional 80 percent could mean big money.

Moses initially patented a version of the invention in 2000, but says that it took finding the right team to incorporate as NanoEar. That took place in 2016, when he joined forces with cofounders Michael Moore and Willem Vermaat, now the company’s president and CFO, respectively. Moore is a mechanical engineer, while Vermaat is a “financial guru;” both are repeat entrepreneurs in the biotech space.

Today, NanoEar has nine active patents. The company’s technical advisors include “the genius behind developing the brains in this device,” Chris Salthouse; NASA battery engineer Will West; Dutch physicist and audiologist Joris Dirckx; and Daniel Spitz, a third-generation master watchmaker and the original guitarist for the famed metal band Anthrax.

The NanoEar concept has done proof-of-concept testing on both cadavers at the University of Antwerp and on chinchillas, which are excellent models for human hearing, at Tulane University. As part of the TMC Innovation Institute program in 2017, the NanoEar team met with FDA advisors, who told them that they might be eligible for an expedited pathway to approval.

Thus far, NanoEar has raised about $900,000 to get its nine patents and perform its proof-of-concept experiments. The next step is to build the prototype, but completing it will take $2.75 million of seed funding.

Despite the potential for making global change, Moses has said it’s been challenging to raise funds for his innovation.

“We're hoping to find that group of people or person who may want to hear their children or grandchildren better. They may want to join with others and bring a team of investors to offset that risk, to move this forward, because we already have a world-class team ready to go,” he says.

To that end, NanoEar has partnered with Austin-based Capital Factory to help with their raise. “I have reached out to their entire network and am getting a lot of interest, a lot of interest,” says Moses. “But in the end, of course, we need the money.”

It will likely, quite literally, be a sound investment in the future of how we all hear the next generation.

Houston VC funding surged in Q1 2025 to highest level in years, report says

by the numbers

First-quarter funding for Houston-area startups just hit its highest level since 2022, according to the latest PitchBook-NVCA Venture Monitor. But fundraising in subsequent quarters might not be as robust thanks to ongoing economic turmoil, the report warns.

In the first quarter of 2025, Houston-area startups raised $544.2 million in venture capital from investors, PitchBook-NVCA data shows. That compares with $263.5 million in Q1 2024 and $344.5 million in Q1 2023. For the first quarter of 2022, local startups nabbed $745.5 million in venture capital.

The Houston-area total for first-quarter VC funding this year fell well short of the sum for the Austin area (more than $3.3 billion) and Dallas-Fort Worth ($696.8 million), according to PitchBook-NVCA data.

While first-quarter 2025 funding for Houston-area startups got a boost, the number of VC deals declined versus the first quarters of 2024, 2023 and 2022. The PitchBook-NVCA Monitor reported 37 local VC deals in this year’s first quarter, compared with 45 during the same period in 2024, 53 in 2023, and 57 in 2022.

The PitchBook-NVCA report indicates fundraising figures for the Houston area, the Austin area, Dallas-Fort Worth and other markets might shrink in upcoming quarters.

“Should the latest iteration of tariffs stand, we expect significant pressure on fundraising and dealmaking in the near term as investors sit on the sidelines and wait for signs of market stabilization,” the report says.

Due to new trade tariffs and policy shifts, the chances of an upcoming rebound in the VC market have likely faded, says Nizar Tarhuni, executive vice president of research and market intelligence at PitchBook.

“These impacts amplify economic uncertainty and could further disrupt the private markets by complicating investment decisions, supply chains, exit windows, and portfolio strategies,” Tarhuni says. “While this may eventually lead to new domestic investment and create opportunities, the overall environment is facing volatility, hesitation, and structural change.”