UH's business school has a new program focused on artificial intelligence thanks to a partnership with Intel. Photo via uh.edu

The University of Houston’s C.T. Bauer College of Business has teamed up with semiconductor chip manufacturer Intel Corp. to provide training in artificial intelligence.

The new artificial intelligence program features a standalone business certificate with two specialized courses; the first course launched in January. Bauer also plans to offer non-degree certificate programs in AI, such as the AI Certificate for Entrepreneurship and AI Certificate for Executive Education.

In a news release, Elizabeth McGee, chief strategy and innovation adviser at Santa Clara, California-based Intel, says the UH initiative will help bridge the AI knowledge gap. An online search indicates hundreds of AI-related jobs are open in the Houston area.

“Digital upskilling, or digital readiness, needs to be a catapult for economic prosperity for everyone and not a dividing point,” McGee says. “I commend the University of Houston for being the first higher education institution to take our award-winning curriculum and lend your expertise in entrepreneurship, your access to the broader Houston community, and supporting this digital upskilling for everyone.”

AI education has taken on a greater sense of urgency as the healthcare and energy sectors, among others, incorporate AI into their operations.

Paul Pavlou, dean of the Bauer College and Cullen Distinguished Chair Professor, says the collaboration between UH and Intel will help propel growth and innovation in Houston’s tech sector. Intel, whose only Texas location is in Austin, is a key player in the expanding AI market.

“Intel has been very generous with their resources, and with our expertise in analytics and faculty research and students’ initiative in bringing new products to life, the opportunities for this collaboration to be transformative are endless,” Pavlou says.

AI is growing at an incredibly rapid pace. According to Precedence Research, the size of the global AI market was estimated at $119.78 billion in 2022 and is expected to reach nearly $1.6 trillion by 2030.

“While some markets, sectors and individual businesses are more advanced than others, AI is still at a very early stage of development overall,” says professional services firm PwC. “From a macroeconomic point of view, there are … opportunities for emerging markets to leapfrog more developed counterparts.”

AI is viewed as both positive and negative in terms of today’s workforce.

“AI is a fast-evolving technology with great potential to make workers more productive, to make firms more efficient, and to spur innovations in new products and services. At the same time, AI can also be used to automate existing jobs and exacerbate inequality, and it can lead to discrimination against workers,” says a report published by the White House in 2022.

Houston Mayor Sylvester Turner and Houston City Council celebrated “AI Innovation and Entrepreneurship Day” at City Hall on Feb. 7. Photo via Facebook

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.