Harvest Green — a unique and innovative community in the greater Houston area — has added a mammoth parcel to its agrihood. Photo courtesy of Harvest Green

One of the hottest trends in Houston's scorching real estate market is the rise of the "agrihood" — what's defined as an "organized community that integrates agriculture into a residential neighborhood."

Now, a suburban neighborhood/agrihood has announced a major expansion, aimed at adding more homes and to the fast-selling community.

Harvest Green, nestled in the Richmond area, has just acquired 630 acres adjacent to the neighborhood, according to ownership company Johnson Development.

That massive addition means some 1,400 homes that will be added to the agrihood-based development. Homesites should be ready for builders by the second quarter of 2022, per Jerry Ulke, general manager of Harvest Green, with sales expected to begin fall of 2022.

A key draw for Harvest Green is its 12-acre farm, which features fields of produce, an orchard, a vineyard, and pens for goats and chickens. Residents can join the farm club and access plots to grow their own produce (under the guidance of professional farmers). A popular farmers market is held the third Saturday of each month.

Meanwhile, future residents can also look forward to the Farmhouse recreation complex, with its fitness center and resort-style pool, trail, and a number of parks and playgrounds. The Messina Hof Harvest Green Winery & Kitchen (read the CultureMap story here) is also located onsite.

This new section will feature a variety of home styles, with designs for properties ranging from 40 feet wide to 75 feet wide, per press materials. Also on tap are additional community amenities, with parks, trails, green space, and a pool planned.

Residents will have access to existing Harvest Green amenities, including the Village Farm. As locals know, Oyster Creek winds through the new property for nearly two miles.

Currently, Harvest Green offers reasonably priced homes starting in the $300,000s by builders including Coventry Homes, David Weekley Homes, and Perry Homes.

"Our farm-themed community has resonated with buyers looking for a more sustainable lifestyle," Ulke continued in a press release.

"The past two years, Harvest Green has ranked among the nation's 50 top-selling master-planned communities, and last year we sold nearly 500 new homes. Because of last year's robust sales, builders had fewer than 100 homesites for all of 2021. This additional land will meet that obvious demand."

For more information, visit the official Harvest Green website.

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This article originally ran on CultureMap.

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Houston brain health co. secures $6.5M for rare disease study

neuro funding

Houston-based Goldenrod Therapeutics, part of Fannin Partners' portfolio, has announced the initial close of a $6.5 million series seed preferred stock round.

The round was led by Ataxia Ventures and an affiliate of Fannin, according to a news release.

Goldenrod Therapeutics plans to use the funding to support manufacturing, formulation optimization, IND-enabling studies and a Phase I study of its drug to treat brain inflammation, known as 11h.

The study will consider how 11h, which blocks the enzyme PDE4, could treat Friedreich’s ataxia (FA), a rare genetic disease that affects movement, speech and balance. To date, other PDE4 inhibitors have proven to regulate neuroinflammation and neuronal signaling, but have had adverse gastrointestinal side effects or have not reached enough of the central nervous system, according to Goldenrod.

The company says its 11h is expected to have "broad applicability" with limited emetric side effects.

“Our 11h program is a next-generation, orally bioavailable, brain-penetrant PDE4 inhibitor, where researchers overcame longstanding limitations associated with earlier PDE4 inhibitors," Dr. Dev Chatterjee, CEO of Goldenrod, said in the news release. "We believe this creates the potential for a best-in-class therapy for Friedreich’s Ataxia and a potential foundation for development across multiple neurodegenerative and neuroinflammatory disorders.”

11h was first developed at the University of Nebraska Medical Center (UNeMed). Houston-based Fannin Partners in-licensed the product 2020 and landed SBIR Phase I funding to support its initial development for opioid use disorder soon after.

Goldenrod has also received funding to study 11h's effectiveness for multiple sclerosis, methamphetamine addiction and cocaine addiction.

Goldenrod says it is developing 11h to target a variety of neurological and inflammatory conditions, including Alzheimer's disease, multiple sclerosis, ALS, substance use disorders, Batten disease, pain and traumatic brain injury.

27 Houston companies make Fortune 500 for 2026, led by energy giants

Houston HQs

Editor's note: This article has been updated to correct the number of companies based in the Dallas-Fort Worth area.

Houston is a giant among U.S. hubs for corporate headquarters.

The 2026 Fortune 500 lists 27 companies based in the Houston area, with many energy companies claiming top spots. Houston ties with Chicago for the second-most Fortune 500 headquarters, preceded only by New York City (53). Dallas-Fort Worth is home to 24 Fortune 500 headquarters.

Texas leads the nation for Fortune 500 headquarters (57), with California in the No. 2 spot and New York at No. 3.

“Texas is the undisputed headquarters of headquarters,” Gov. Greg Abbott said in a news release. “The world’s leading businesses invest with confidence in Texas because of our welcoming business climate, predictable regulatory environment, and skilled and growing workforce. People and businesses are choosing Texas because Texas works.”

The 2026 Fortune 500 ranks the largest U.S. corporations based on revenue in fiscal year 2025.

Here’s a rundown of the 27 Fortune 500 companies based in the Houston area.

  • No. 9 ExxonMobil
  • No. 21 Chevron
  • No. 29 Phillips 66
  • No.55 Sysco
  • No. 75 ConocoPhillips
  • No. 89 Enterprise Products Partners
  • No. 103 Plains GP Holdings
  • No. 133 Hewlett Packard Enterprise
  • No. 149 NRG Energy
  • No. 157 Quanta Services
  • No. 164 Baker Hughes
  • No. 173 Occidental Petroleum
  • No. 179 Waste Management
  • No. 201 EOG Resources
  • No. 204 Group 1 Automotive
  • No. 207 Halliburton
  • No. 223 Cheniere Energy
  • No. 236 Corebridge Financial
  • No. 262 Targa Resources
  • No. 266 Kinder Morgan
  • No. 388 Westlake
  • No. 435 CenterPoint Energy
  • No. 438 APA
  • No. 440 Comfort Systems USA
  • No. 455 NOV
  • No. 488 KBR
  • No. 496 Coterra Energy. Oklahoma City, Oklahoma-based Devon Energy and Houston-based Coterra Energy merged in early May, with the combined company retaining the Devon Energy name and the Houston headquarters.

The Greater Houston Partnership notes the Houston area soon will welcome its 28th Fortune 500 company. Expand Energy (formerly Chesapeake Energy), appearing at No. 362 on the 2026 list, says it’s moving its headquarters from Oklahoma City to Spring this year.

As the natural gas producer prepares to relocate to Texas, it’s hunting for a new leader. Nick Dell’Osso stepped down as president and CEO earlier this year. Board Chairman Michael Wichterich is interim president and CEO.

Dell’Osso became president and CEO of Oklahoma City-based Gulfport Energy effective May 28.

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This article first appeared on EnergyCapitalHTX.com.