Houston to host 6 Italian aerospace companies with new program

space it up

Six Italian companies are coming to the Space City to accelerate their businesses thanks to a new program. Photo via nasa.gov

It's an Italian invasion in Houston — and it's happening in the name of accelerating innovation within aerospace.

For the first time, Italy has announced an international aerospace-focused program in the United States. The Italian Trade Agency and Italian Space Agency will partner with Space Foundation to launch Space It Up, an initiative that will accelerate six companies in Houston.

“The launch of Space It Up marks a pivotal moment in our ongoing commitment to nurturing innovation and facilitating global partnerships," Fabrizio Giustarini, Italian Trade Commissioner of Houston, says in a news release. "This program serves as a testament to the collaborative spirit that defines the aerospace industry. It represents the convergence of Italian ingenuity and Houston's esteemed legacy in space exploration, setting the stage for unprecedented advancements."

The Italian companies in the inaugural cohort represent various areas of cutting-edge aerospace innovations and technologies. The selected companies are:

  • Arca Dynamics, a space traffic management and Earth observation service provider.
  • Delta Space, a low-cost satellite connectivity for sensors and launch services.
  • Involve Space, a pseudo-satellite platform and intelligent software to enable access to space.
  • Nabu, an IoT and data analysis provider.
  • NOVAC, which is producing an innovative shapeable all-solid-state structural supercapacitor.
  • T4i, developing innovative engines to serve small satellite platforms.

ITA and Space Foundation will provide a six-week immersive program focused on the most important aspects of the aerospace industry that will also include business events, networking opportunities, and, ultimately, connect the Houston aerospace community with the Italian startups.

Space It Up will launch its kick-off event at noon on September 1 at Ion Houston, followed by a demo day on September 27. The Demo Day will demonstrate the transformative impact on the aerospace industry by presenting the progress on break-through technologies and projects like the acceleration programs.

The Houston office is one of five ITA offices in the U.S. Other partnerships include Houston-based digital platform leader Village Insights, which will serve as a digital epicenter for Italy’s aerospace companies.

“From the cradle of Renaissance to the frontiers of the cosmos, Italy’s heritage of space innovations knows no bounds,” Keli Kedis Ogborn, Space Foundation vice president of space and entrepreneurship, says in a news release. “With a legacy of scientific advancements, Italy continues to script a new chapter in history, this time with a broader focus on international collaboration and impactful growth to the evolving global space ecosystem.”

From Your Site Articles
Here's what Houston tech and startup news trended this year in InnovationMap's space tech category. Photo via NASA

Looking back: Top 5 most-read Houston space tech articles of the year

2022 in review

Editor's note: As 2022 comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. In the Space City, there were dozens of space tech stories, from experts' thoughts on commercialization to the IPO of a Houston company. Here are five Houston space tech-focused articles that stood out to readers this year — be sure to click through to read the full story.

Overheard: Houston needs to strengthen infrastructure, workforce to maintain Space City status

Space experts discussed the city's role in the space industry at a recent event. Photo via NASA

In no time at all, humans will return to the moon and as they make the first spacewalks in fifty years — wearing suits designed in Houston — they will call down to earth, and only one city in the world will be named on the radio transmissions.

Houston is the Space City — but what will it take to maintain that moniker? This was a big topic of the Greater Houston Partnership's second annual State of Space event hosted on Tuesday, October 11.

A diverse and impressive panel discussed the Space City's future, the upcoming moon missions, commercializations, and more. Read more.

Houston-based space tech company to go public via SPAC merger

The deal between Intuitive Machines and a SPAC is expected to close in the first quarter of 2023 and would value the combined company at $815 million. Photo courtesy of Intuitive Machines

A Houston-based space exploration company that’s been tapped by NASA to take cargo to the moon plans to go public through a SPAC merger with a New York-based shell company.

Intuitive Machines LLC, founded in 2013, aims to merge with New York City-based Inflection Point Acquisition Corp., a special purpose acquisition company (SPAC). Once the merger is completed, shares of the combined company (Intuitive Machines) will trade on the Nasdaq stock market under the ticker symbol LUNR.

The deal, expected to close in the first quarter of 2023, would value the combined company at $815 million. Read more.

Space City News: Houston Spaceport receives grant, unicorn hires architecture firm

Catch up on two big pieces of news landing at the Houston Spaceport. Image via fly2houston.com

The Space City is starting 2022 off strong with news launching out of the Houston Spaceport — a 400-acre space in Southeast Houston.

The two big headlines include a unicorn company releasing the latest details of its earthbound project and fresh funds from the state to support the space ecosystem in Texas. Read more.Read more.

Overheard: Space experts discuss commercialization, innovation, and Houston's future

What's Houston's role in the modern era for aerospace? And how can the industry foster public-private collaboration? Experts weighed in at a recent event. Photo via NASA

The aerospace industry — much more than other sectors — is run by a mixture of civil, commercial, and military players. And each of these verticals operate very differently.

At a Houston Tech Rodeo event called "Lasso the Moon" put on by Space Force Association and TexSpace, aerospace experts representing various entities — from startups to big tech to education and military organizations — discussed the future of space innovation. Read more.

Iconic Houston-area landmark rockets to No. 1 in new list of best employers in Texas

Johnson Space Center astronauts and team enjoy the best workplace in Texas. Johnson Space Center/Facebook

NASA must be over the moon about a new ranking of the best employers in Texas.

A new list from Forbes and Statista puts NASA at No. 1 among the state’s major employers, both those based in Texas and those with a significant presence here.

NASA’s $1.5 billion Johnson Space Center complex occupies more than 1,600 acres in Clear Lake. The site, home to the space agency’s mission control and astronaut training operations, employs roughly 3,000 NASA workers, along with thousands of NASA contractors. NASA’s headquarters is in Washington, D.C.

It’s estimated that Johnson Space Center contributed more than $4.7 billion to the Texas economy in 2018. Read more.

Houston-based Venus Aerospace has raised $20 million — and is one step closer to providing one-hour global travel. Photo courtesy of Venus Aerospace

Houston aerospace startup secures $20M series A investment round

money moves

A year after raising $3 million in seed funding, a Space City startup has closed its high-flying series A round to the tune of $20 million.

Venus Aerospace, which is working on a zero-carbon emission spaceplane that will enable one-hour global travel, closed its series A funding round led by Wyoming-based Prime Movers Lab. The firm has a few dozen breakthrough scientific companies in its portfolio, including another Houston-based, space-focused startup, Axiom Space. The round also saw participation from previous investors: Draper Associates, Boost, Saturn 5, Seraph Group, Cantos, The Helm & Tamarack Global.

Venus Aerospace was founded by Sarah "Sassie" and Andrew Duggleby, who serve as the company's CEO and CTO, respectively, in 2020 in California. The Texas A&M University alumni later moved the business into its current facilities in the Houston Spaceport.

"The U.S. is in the middle of a global race for hypersonic technology, and the breakthroughs being developed by Sassie, Andrew, and their team have numerous civilian and defense applications," says Prime Movers Lab General Partner Brandon Simmons in a news release. "Venus hit critical engine tests, vehicle design, and growth milestones that make me tremendously excited about the future of American hypersonic flight."

According to the release, the company will use the fresh funding on enhancing its three main technologies: a next-generation rocket engine, aircraft shape, and leading-edge cooling system, which allows for the Venus spaceplane to take off from existing spaceports.

"These recent advances in technology finally enable a spaceplane, a vehicle long imagined, but only now possible," says Andrew Duggleby in the release. "We will use this round of funding to get into flight testing and engine testing at Spaceport Houston. Bringing this technology forward into systems, drones and ultimately spaceplanes, it will take both new space veterans and bright new minds to solve. We've gone from impossible to hard, and this investment will allow us to knock down the next few steps."

The past year has represented significant growth for Venus, with developing contracts with the government and building out the company's team — and the company still has eight positions listed on its website. After building out and testing its technology, Venus also started a ground test campaign at Spaceport Houston.

"We are excited to continue our partnership with Prime Movers Lab and our other great investors. In the past year, with our initial funding, we have scaled from 3 people to 40. These are the world's best rocket scientists, engineers, and operators," says Sassie Duggleby in the release. "With this funding, we will continue to push forward toward our next technical milestones, hire great people, and scale our organization. We are excited to continue engineering the future of high-speed aviation."

These five space tech stories were among the most read of 2021. Photo via NASA.gov

These are Houston's top space innovation stories of the year

2021 in review

Editor's note: As 2021 comes to a close, InnovationMap is looking back at the year's top stories in Houston innovation. When it came to the space innovation and technology — from commercial space exploration to space tech and research funding — in Houston, five stories trended among readers.

Overheard: Experts share how Houston can lead commercial space exploration

Vanessa Wyche, director of the Johnson Space Center, gave the keynote address at this year's State of Space event. Screenshot via houston.org

Is the Space City poised to continue its reign as an innovative hub for space exploration? All signs point to yes, according to a group of experts.

The Greater Houston Partnership hosted its annual State of Space this week. The virtual event featured a keynote address from Vanessa Wyche, director of NASA Johnson Space Center, and a panel moderated by David Alexander, chair of aerospace and aviation committee at the GHP and the director of the Rice Space Institute.

The conversations focused on the space innovation activity happening in Houston, as well as an update on the industry as a whole has space commercialization continues to develop. All the speakers addressed how Houston has what it takes to remain a hub for the sector.

"The future looks very bright for Houston that we will remain a leader in Houston spaceflight," Wyche says in her address. Click here to read the full article.

Houston, we're trying to fix the problem: Aerospace challenges and future exploration

You've heard "it's not rocket science" throughout your life, but but turns out that aerospace exploration — even in 2021 — is still very hard. Photo via Pexels

If there is anything that goes hand in hand so perfectly, it's Houston and Space. Houston is home to the Johnson Space Center, named after former president Lyndon B. Johnson, and is home to revolutionary space research projects and spaceflight training for both crew members and flight controllers. While it's every kid's dream to become an astronaut, have you ever wondered why rocket science is actually so difficult?

Though the space race of the '70s has been over for some time, the new space race — the race to Mars and the commercialization of space tourism — has just started. Elon Musk, Jeff Bezos, and Richard Branson are spearheading the "Billionaire space race." But even with their billions being put into developing spaceports, NASA rocket partnerships, and planning future Mars missions, rocket science is just as difficult to implement as it was the first time around.

So why, even with billions of dollars at their disposal and many companies pushing for more funding, are scientists and engineers still struggling to make rocket travel an everyday thing? Here are some of the countless reasons why rockets science is insanely difficult, no matter how much money you throw at it. Click here to read the full article.

Fresh funds: 2 Houston organizations dole grants to advance research

Here's what researchers raked in the cash to support their research. Photo via Getty Images

Funding fuels the research that supports the innovations of tomorrow. Two Houston-based scientific organizations announced funding recipients that are working on advancing research in space health and chemistry.

The Translational Research Institute for Space Health, known as TRISH, at Baylor College of Medicine has announced almost $4 million in grants to four research teams. As more and more plans to launch humans into space continue to develop, TRISH is working to support research addressing human health in space. Click here to read the full article.

Space-focused fund with HQ in Houston rockets toward $20M goal

SpaceFund, based in Houston and Austin, has almost reached halfway for its $20 million fundraise. Photo via NASA/Unsplash

A venture capital firm co-located in Houston and Austin has announced a recent closing of a $20 million fund.

SpaceFund has raised $9 million toward its its $20 million BlastOff Fund as of this week — surpassing its initial first close goal of $5 million.

"We are thrilled to see how many investors are placing their trust in our team," says SpaceFund founder Rick Tumlinson in a news release. "We spent a lot of time slowly and carefully developing our processes and credibility, so we can better serve both investors and the amazing space startup community, and it's paying off."

Launched in 2019 with an initial fund that closed in August of 2020, SpaceFund has already invested in 13 exciting space startups. The new fund will build on those investments while also expanding its portfolio, according to the release.

"SpaceFund is about combining a bold approach with a very conservative diligence and investment process," says Meagan Crawford, SpaceFund's managing partner, in the release. "The BlastOff Fund continues our careful growth plan but is designed to accelerate our ability to place investment into those companies that are leading the Space Revolution." Click here to read the full article.

New Houston accelerator supporting BIPOC in aerospace announces inaugural cohort

The Ion's Aerospace Innovation Accelerator for Minority Business Enterprises has named four companies to its first cohort. Photo courtesy of The Ion

A new accelerator program that is focused on aerospace innovation and supporting entrepreneurs who are Black, Indigenous, and people of color has announced its first cohort.

The Ion's Aerospace Innovation Accelerator for Minority Business Enterprises, or AIA for MBEs, has named the four companies that well be a part of its inaugural cohort. The 12-week program will guide the entrepreneurs through the development of their innovations, the growth of their businesses, and the development of relationships with mentors, corporate partners, and stakeholder networks.

"Aerospace contains a myriad of dimensions and by demystifying the industry in the form of the AIA for MBEs, we are able to build a more inclusive innovation ecosystem," says Christine Galib, senior director of programs at The Ion, in a news release. "It's our goal to not only support participants to be successful, but to open the playing field for other minority business enterprises hoping to enter the space." Click here to read the full article.

You've heard "it's not rocket science" throughout your life, but but turns out that aerospace exploration — even in 2021 — is still very hard. Photo via Pexels

Houston, we're trying to fix the problem: Aerospace challenges and future exploration

guest column

If there is anything that goes hand in hand so perfectly, it's Houston and Space. Houston is home to the Johnson Space Center, named after former president Lyndon B. Johnson, and is home to revolutionary space research projects and spaceflight training for both crew members and flight controllers. While it's every kid's dream to become an astronaut, have you ever wondered why rocket science is actually so difficult?

Though the space race of the '70s has been over for some time, the new space race — the race to Mars and the commercialization of space tourism — has just started. Elon Musk, Jeff Bezos, and Richard Branson are spearheading the "Billionaire space race." But even with their billions being put into developing spaceports, NASA rocket partnerships, and planning future Mars missions, rocket science is just as difficult to implement as it was the first time around.

So why, even with billions of dollars at their disposal and many companies pushing for more funding, are scientists and engineers still struggling to make rocket travel an everyday thing? Here are some of the countless reasons why rockets science is insanely difficult, no matter how much money you throw at it.

Small talent pool

The Apollo astronauts were the best of the best — and the hundreds of thousands of engineers and rocket scientists behind the scenes were just as talented. But getting to the point in one's career where you have the right background experience and the right hands-on work and real-life experience to create a safe rocket is difficult. The talent pool that SpaceX, Virgin Galactic, and Blue Origin are working with is extremely small and notoriously competitive. As these programs continue to build in credibility, it may be easier to find talent, but few engineers want to be tied to a failed launch.

The risk of failure

Usually, when you fail at something like a math test or a driver's exam, the ramifications aren't too big. But with space travel, a small problem can quickly turn into a deadly situation for those on board the rocket. Think back to the Challenger explosion in 1986. The success of previous missions (not to mention the administrative corner-cutting) led to a false sense of security when in reality they were still embarking on the insanely difficult feat of launching humans into space. The risk of failure is so great, many commercial manufacturers are cautious to put their weight behind an operation that could in all likelihood come crashing back down to Earth.

Rocket construction

Think back to when you were in school learning about Isaac Newton's Third Law of Motion: for every action, there is an equal and opposite reaction. It's a simple idea, but complex in reality. That law of motion forms the basis for rocket science: the combustion of rocket fuel down into the earth is one action, so the opposite reaction causes the rocket to launch upward into space. But the engineering that's needed for a launch to take place is the hard part.

As mentioned in a 2012 NPR article, there are millions of pieces in every rocket, and "therefore millions of opportunities to make errors — to make errors in calculations, to make errors in construction." The devastating Challenger mission failure is often attributed to faulty O-rings — it's a simple piece of equipment and can often be overlooked.

Even after hundreds of successful launches over the years, rocket construction is just as complex, and the process of shooting humans into space cannot be distilled to a law of motion when there is so much more involved to make that process happen.

Public perception

Throughout the '70s, Americans were enthralled by the idea of the space race and becoming the first country to set foot on the moon. But the public's passion died down after that initial landing. Today, the public perception of current space projects is making doing the actual rocket science and engineering difficult.


Objections against NASA's waste of taxpayer money on "futile" missions and the idea that space travel will only be for the mega-wealthy make any conversation around actual scientific discovery second to politics. Not to even mention the newly minted Space Force. Engineers and scientists have to navigate a hoard of political, financial, and PR battles to even get to do the work of getting people back into space.

The bottom line

Rocket science is thought of as one of the most difficult fields for a reason. Building a piece of technology capable of going into space and even housing people inside is a relatively new feat when considering the span of time. As the billionaire space race continues to unfold, scientists and engineers behind the scenes are creating feats of engineering on a regular basis that will shape the future of space travel. But, if you want to just get a taste of space life, without all the schooling, then a trip to the Johnson Space Center is for you.

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Natasha Ramirez is a Utah-based tech writer.

Catch up on space news — from new partnerships at Rice University and the latest snub for the Space City. Photo via NASA.gov

Space City News: Houston passed over for military HQ, Rice forms new partnerships

aerospace updates

It's been a busy few days for space news, and in Houston — the Space City — it's all relevant to the continued conversation of technology and innovation.

With so much going on — from Houston being passed over for the Space Command's headquarters and Rice receiving $1.4 million in federal funds for a new hub — here's what you may have missed in space news.

The Ion awarded $1.4M to launch Aerospace Innovation Hub

The Ion will be home to the Aerospace Innovation Hub, thanks to a federal grant. Courtesy of Rice University

Through a partnership with NASA's Johnson Space Center and DivInc, The Ion has been awarded $1.4 million in federal funding to create its Aerospace Innovation Hub. The ASCI-Hub will support and develop regional minority business enterprises addressing aerospace-related challenges.

"Landing this award is another win for the region that leverages the unique strengths of the crewed space program at NASA JSC," says Jan E. Odegard, interim executive director of the Ion, says in a news release. "As Houston was critical to landing men on the moon in the late-'60s, the Ion's Aerospace Innovation Hub will be key not only to advancing the future of spaceflight, including the mission to Mars in the future, but also to tackling challenges facing our everyday lives here on Earth."

The hub will provide NASA's expertise and resources across robotics, medicine, health support systems, additive manufacturing, and more — as well as community events, education and training, and an accelerator program.

"We're eager to partner with the MDBA, Rice University and the Ion to help develop and grow minority entrepreneurs and accelerate innovative and tech-forward solutions in Houston," says Vanessa Wyche, deputy director of the JSC, in the release. "This partnership builds toward NASA's goals to enhance scientific and technological knowledge to benefit all of humankind and catalyze economic growth, as we propel commercialization of space and extend our presence in the solar system."

Opening in 2021, the Ion announced $1.5 million in grant funds in September. Those funds are going toward accelerators, which will collaborate with the Aerospace Innovation Hub.

"While we have taken many small — and valuable — steps over the past few years, this is one giant leap forward for our efforts to promote sustainable inclusion in Houston's entrepreneurial and technological ecosystem," says Christine Galib, senior director of programs at the Ion, in the release.

The Air Force announces 6 potential sites for Space Force base — and Houston misses the mark

Houston will not be considered for the Space Command HQ — but Texas isn't completely out of the running. U.S. Air Force Graphic by Rosario "Charo" Gutierrez

The United States Department of the Air Force announced the six candidate locations for the U.S. Space Command Headquarters — and Houston didn't make the cut.

The six locations include:

  • Kirtland Air Force Base in New Mexico
  • Offutt AFB in Nebraska
  • Patrick AFB in Florida
  • Peterson AFB in Colorado (where temporary operations are located)
  • Port San Antonio in Texas
  • Redstone Army Airfield in Alabama

The Air Force evaluated self-nominated cities from across 24 states based on factors related to mission, infrastructure capacity, community support, and costs to the Department of Defense, according to a press release. U.S. Space Command Headquarters location announcement is expected in early 2021.

"We are disappointed that Houston is not among the finalist locations for the U.S. Space Command," Susan Davenport, chief economic development officer for the Greater Houston Partnership, says in a statement to the Houston Chronicle. "We believe we put together a strong case for why Houston should be chosen. We will continue to work with the U.S. Air Force and other branches of the military on future opportunities and we will remain vigilant in our pursuit of aerospace industry opportunities for this region."

Rice Space Institute to collaborate with Canada

The Rice Space Institute has a new partner is Canada. Photo courtesy of NASA

Rice University's Rice Space Institute has signed a memorandum of understanding with the Consulate General of Canada in Dallas to collaborate on space science and technology.

The parties made the collaboration official at a virtual event on November 20. RSI Director David Alexander OBE, a Rice professor of physics and astronomy, says the partnership is key to the continued commercialization of space exploration.

"What's different about this agreement is that with the rapid growth of commercial space worldwide and the strength of the aerospace industry in Houston, it presents a new pathway for potential interactions between Canadian science and industry and commercial entities not just in the Houston region but around the world," he says in a news release. "It's a nice, complementary aspect to our connection with NASA."

The United States has collaborated with Canada on space exploration for decades, and Canada's government is committed to advancing space technology.

"This MOU with the Rice Space Institute comes at an exciting time in human space exploration," says Rachel McCormick, the Consul General of Canada in Dallas and Canada's official representative in the U.S. South Central region, in the release. "In 2019, the Government of Canada announced an investment of $1.9 billion over 24 years for the next generation of smart, AI-powered space robotics for the U.S.-led Lunar Gateway program.

"We are also providing $150 million over five years for the Lunar Exploration Accelerator Program," she continues. "LEAP will fund the development and demonstration of lunar science and technologies in fields that include AI, robotics and health."

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12 health tech startups named to Houston accelerator's next bootcamp

onboarding

Twelve promising health tech startups have been selected for the annual bootcamp at the Texas Medical Center.

TMC's Accelerator for HealthTech selected 12 companies from around the world and across specialties for the opportunity. Following the bootcamp, TMC will move forward a selection of startups to join its accelerator.

"Houston, a thriving hub for innovation, is rapidly becoming the destination of choice for healthtech companies," reads a statement from TMC. "With the Texas Medical Center at its heart, the city offers unparalleled resources, cutting-edge research facilities, and a collaborative spirit that fosters growth. This environment not only attracts startups but also provides them with the necessary tools to navigate the complex landscape of healthcare commercialization."

Through the bootcamp, the participants will engage with advisors and industry experts, refine their business models, prepare for market entry, and have opportunities for collaboration with the TMC's member organizations.

The selected bootcamp companies, according to TMC, include:

  • Alyf, founded in Newport Beach, California, has developed a personalized cardiac care system that brings patients and providers together with real-time, AI-driven insights, enabling them to monitor, track, and improve cardiac health outcomes collaboratively.
  • Seoul, South Korea-based Deepmetrics leverages artificial intelligence to provide ICU smart care services that optimize medical device settings, such as mechanical ventilators, to reduce mortality and shorten the length of stay for critically ill patients worldwide.
  • EquityQuotient, from New York City, is a healthcare intelligence platform that automates compliance and provides actionable insights by aggregating public, private, and first-party data, using proprietary analytics to help leaders address disparities, improve outcomes, and lower care costs.
  • Also from New York City, Ethermed's AI-powered solution streamlines prior authorizations, eliminating up to 90 percent of auths and 70 percent of the labor involved. Ethermed requires no workflow changes, is fully auditable, and offers aligned incentives from a mission-driven, human-focused company.
  • Fibricheck, based in Hasselt, Belgium, transforms ordinary smartphones into regulated digital heart rhythm monitors, offering unparalleled access to cardiovascular diagnostics for patients and streamlined workflows for physicians.
  • Austin-based NearWave has developed a non-invasive, AI-powered handheld imaging device that can predict breast cancer therapy response within seven days.
  • Pragmaclin, founded in Newfoundland, Canada, developed a cutting-edge PRIMS (Parkinson’s Remote Interactive Management System) that leverages depth cameras and machine learning to monitor and assess Parkinson’s Disease symptoms, offering healthcare professionals remote and in-clinic insights to enhance treatment decisions.
  • Somnair, a Baltimore, Maryland, company, is developing a non-invasive neurostimulation oral appliance for treating obstructive sleep apnea, offering a sleek, retainer-sized device that provides an effective alternative to CPAP or invasive surgery for millions of patients.
  • Vancouver, Canada-headquartered Total Flow Medical is developing solutions to enhance the quality of care and life for patients requiring the use of a heart-lung machine during surgery or life support.
  • Tympulse, hailing from Dublin, Ireland, is commercializing TympanoColl, an innovative and disruptive solution for eardrum (Tympanic Membrane) repair in an outpatient setting through the ear canal.
  • Perth, Australia-based Vital Trace is developing a continuous lactate monitor for real-time, accurate detection of fetal distress.
  • New York City's WorkUp is a healthcare-specific talent pipeline management platform that connects students with tailored resources for their clinical career journey, providing personalized support as their needs evolve.

University of Houston-founded company secures $2.5M in NIH grant funding

all in the timing

You could say that the booming success of Houston biotech company CellChorus owes very much to auspicious TIMING. Those six letters stand for Time-lapse Imaging Microscopy In Nanowell Grids, a platform for dynamic single-cell analysis.

This week, CellChorus announced that the company, along with The University of Houston, has been awarded up to $2.5 million in funding from the National Center for Advancing Translational Sciences (NCATS) at the National Institute of Health. A $350,000 Phase I grant is already underway. Once predetermined milestones are achieved, this will lead to a two-year $2.1 million Phase II grant.

The TIMING platform was created by UH Single Cell Lab researchers Navin Varadarajan and Badri Roysam. TIMING generates high-throughput in-vitro assays that quantitatively profile interactions between cells on a large scale, particularly what happens when immune cells confront target cells. This has been especially useful in the realm of immuno-oncology, where it has demonstrated its power in designing novel therapies, selecting lead candidates for clinical trials and evaluating the potency of manufactured cells.

“By combining AI, microscale manufacturing and advanced microscopy, the TIMING platform yields deep insight into cellular behaviors that directly impact human disease and new classes of therapeutics,” says Rebecca Berdeaux, chief scientific officer at CellChorus. “The generous support of NCATS enables our development of computational tools that will ultimately integrate single-cell dynamic functional analysis of cell behavior with intracellular signaling events.”

Houston’s CellChorus Innovation Lab supports both the further development of TIMING and projects for early-access customers. Those customers include top-25 biopharmaceutical companies, venture-backed biotechnology companies, a leading comprehensive cancer center and a top pediatric hospital, says CEO Daniel Meyer.

CellChorus’s publications include papers written in collaboration with researchers from the Baylor College of Medicine, Houston Methodist, MD Anderson, Texas Children’s Hospital, the University of Texas and UTHealth in journals including Nature Cancer, Journal of Clinical Investigation and The Journal for ImmunoTherapy of Cancer.

The new Small Business Technology Transfer (STTR) award will specifically support the development of a scalable integrated software system conceived with the goal of analyzing cells that are not fluorescently labeled. This label-free analysis will be based on new AI and machine learning (ML) models trained on tens of millions of images of cells.

“This is an opportunity to leverage artificial intelligence methods for advancing the life sciences,” says Roysam. “We are especially excited about its applications to advancing cell-based immunotherapy to treat cancer and other diseases.”

The Houston-born-and-bred company couldn’t have a more appropriate home, says Meyer.

“Houston is a premier location for clinical care and the development of biotechnology and life sciences technologies. In particular, Houston has established itself as a leader in the development and delivery of immune cell-based therapies,” the CEO explains. “As a spin-out from the Single Cell Lab at the University of Houston, we benefit from working with world-class experts at local institutions.”

In May, the company received a similar $2.5 million SBIR grant from NCATS at the NIH. Also this summer, CellChorus's technology was featured in Nature Cancer.

Bridging the skills gap: How recent college grads can help address urgent staffing needs

guest column

With the current low unemployment rate, locating seasoned and talented staffers who require minimal training is no small task, especially within the high-tech sector. At the same time, college graduates are hungry for new opportunities. In fact, according to the Federal Reserve Bank of St. Louis, many new workforce members are currently underemployed. Approximately 4 in 10 are working in a job that does not utilize the skills they recently obtained on a college campus.

On the employer side, there’s the fear of excessive onboarding needs. On top of that, many hiring managers are afraid that recently trained staffers will simply move on to a new opportunity in a few short years or even months.

But when faced with multiple open positions, is it worth taking the chance on the newest members of the workforce? Here’s some advice on how to successfully navigate the current hiring atmosphere, where college graduates may play a big role in combatting staffing shortages.

Consider culture fit

Hard skills are always important. But at the same time, recognize bright and energetic applicants equipped with a baseline of strong knowledge also tend to be rapid learners. These individuals can often get up to speed quickly as long as they receive the appropriate level of training and mentoring over their first few months on the job. In short, there are many cases where hard skills can be taught.

But how about soft skills?

Identifying candidates who understand and appreciate the company’s culture is a separate but critically important issue. When considering whether to bring an individual on board, be sure to assess all of their compatibilities as well. Often, some extra training for an employee who already values and appreciates the company environment results in a staff member who will stay with and benefit the organization for many years to come.

Look for transferable skills

In the current highly competitive hiring atmosphere, it can be difficult to locate candidates with skills that perfectly align with the needs of open positions. Therefore, it’s important for HR staff and hiring managers to consider transferrable skills. While an individual candidate may not be familiar with a particular software solution, do they have any experience that suggests they are well-equipped to navigate relatively similar systems? Be sure to closely review resumes and CVs that might reveal these hidden strengths. In addition, make certain your list of candidate interview questions is crafted to elucidate this kind of information. Remember that recent college graduates often lack significant interview experience. As a result, you may need to pose specific questions that get to the heart of the information you are seeking. For example, you might ask a candidate to relay past experiences where they needed to learn a new skill or solve a complex problem rapidly. This helps identify whether they can navigate new waters in the workplace or whether they can translate previously held skills into new ones.

Benefits of in-house development programs

Skilled employee shortages tend to surface repeatedly. Even if you don’t have any openings right now, things can change rapidly in a matter of months or even weeks. Because this is the case - especially in the technology sector - consider launching internal training programs that help recent hires learn new skills or sharpen older ones. One option would be in-house training by a skilled staffer as part of the new employee onboarding process. Other possibilities include online learning sessions or a partnership with a local college. Training programs can also be launched to help longtime employees learn new skills as emerging, modernized systems are introduced into the workplace, benefitting the company’s entire workforce.

Track new employee progress

All new employees — whether they are recent college grads or more established members of the workforce - can benefit greatly from a performance review process that features frequent check-ins throughout the initial stages of employment. Supervisors should try to meet weekly or biweekly with new staff during their onboarding process to assess their progress in learning new skills, while identifying needs for additional training. Managers should also regularly communicate with mentors assigned to new employees to ensure skills are developed in a positive learning atmosphere.

In addition to any perceived hurdles, companies should also consider the many benefits of hiring recent college graduates. In some cases, they might bring with them new insights and experiences with emerging technologies. They often arrive with an eagerness to learn and they can introduce ideas and energy, creating increased enthusiasm in the workplace.

When it comes to filling vacant positions, there are many cases where considering recent college graduates can greatly benefit your company. A little training and mentoring can often go a long way and sometimes, taking a chance on a yet unproven, but smart and energetic candidate can land a professional who will benefit the organization for years or even decades to come.

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Jill Chapman is a director of early talent programs with Insperity, a leading provider of human resources and business performance solutions.

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