Exclusive: New Houston accelerator reveals its inaugural cohort and announces strategic partner

Smart Cities

The Ion Smart Cities Accelerator — named for its to-be home, The Ion — announced the 10 companies selected for the first cohort. Courtesy of Rice University

The Ion Smart Cities Accelerator launched earlier this year with a goal of engaging startups from around the world to solve some of Houston's most prevalent challenges. Backed by Intel and Microsoft and partnered with the city of Houston and Station Houston, the program has developed a curriculum and selected its first cohort.

Ten startups from around the world — half of which from right here in Houston — were selected to be a part of the program. And narrowing down to 10 was tough for the program's judges, says Christine Galib, director of the Ion Smart Cities Accelerator.

"Selecting the participants for our first cohort was difficult, due to this amazing pool of talent — that's always the problem you want to have," she tells InnovationMap.

The program will be a 10-month process, beginning Wednesday, September 4. The accelerator's Demo Day is scheduled for December 4, and then the participants will complete a pilot program with the city from January to June, Galib says.

Based on the issues the cohort aims to solve — resilience and mobility — the program and the city of Houston decided on Near Northside as a focus for the companies.

"We focused on aligning to the needs of the city of Houston and our spotlight community, Near Northside," Galib says. "We really considered the focus areas that we have identified that were needs or challenges in the area, like aging infrastructure or health and safety."

The entrepreneurs will attend local meetings, connect with the community, and zero in on the neighborhood for solutions. This provides a more accessible avenue of integration for each of the companies' technologies and allows for the entrepreneurs to receive feedback in real time from the community.

"One of my biggest things with the accelerator is technology will be for the people, and not the other way around. We're really hoping that we can build relationships with community members in Near Northside such that they'll be able to have access to our startups and their technology in a very integrated way."

Along with this new neighborhood focus, the program also announced a partnership with the University of Houston.

"We're collaborating with the UH Technology Bridge such that professors, researchers, and startups associated with UH can have a pipeline from the world of academia and research to industry and urban planning," says Galib.

Here are 10 selected startups for the inaugural cohort.

Aatonomy

Houston-based Aatonomy has developed a device that allows for Houston drivers to instal self-driving technology in their own vehicles.

"They're basically Tesla's autopilot — but for cars we already own," Galib says.

The technology makes for safer, smarter driving around town.

AeoShape

Another homegrown company, AeoShape is in the business of compiling data and making it easier to use — from facial analysis to location-based services, the company is taking data and organizing it to more easily use it for finding solutions or strategies.

"Imagine having all the big data served up anywhere at any time in a comprehensive, visual way," Galib says.

BlocPower

Based in New York, BlocPower is connecting the dots in the consumer energy world. The startup links up with government entities, utilities contractors and more to engage IoT, machine learning, and structured finance technology to better provide clean energy in American cities.

"This is pairing the different segments in the building and infrastructure world in a way that makes sense so that they can build in an integrated way," Galib says.

GoKid

Another New York company, GoKid has a solution for carpooling. In a world so conveniently filled with ridesharing technology, busy parents still struggle to find safe rides home for their kids. The free app allows for parents to connect with one another in a way never before been optimized for school pick-up and drop-off.

"We see GoKid really working with our schools here to make ridesharing safer," Galib says. "We really like them because they were a solution for the ridesharing challenge — a lot of parents who might need carpooling services don't necessarily trust an Uber driving that they don't know."

Kriterion

Artificial intelligence company Kriterion is based in South Africa, but will soon call Houston home. The company takes AI a step further in its industry and infrastructure approach.

"We see their platform shaping three areas of Houston: waste management, power system management, and pothole detection and maintenance management," says Galib.

Sensytec

Sensytec comes out of the University of Houston and uses is technology to monitor, analyze, and quantify cement and concrete conditions.

"We thought this was pretty cool to have in our cohort because Houston is quite the concrete jungle," says Galib.

The company was also recently named a top startup in MassChallenge Texas' inaugural Houston cohort.

SlideX

Houston-based SlideX has solutions for everyone's daily struggle: Parking. The company's technology has applications for finding parking in the city — including a 3D map to help direct you — and even for paying for parking.

"They call themselves 'the next generation of intelligent parking,'" Galib says.

Umanity

San Francisco-based Umanity has created a philanthropic supply chain tool. The technology can match and map local nonprofit needs to volunteers and donations, plus provide real-time analytics.

"This is kind of the epitome of doing good and adds a very strong social enterprise and community base component to our startups," says Galib.

Wyzerr

Kentucky startup Wyzerr specializes in easy-to-use surveys.

"We think Wyzerr can provide a good feedback platform where the city of Houston, businesses, and nonprofits can easily engage with people all over the city to find out how satisfied they are with the businesses and services the city provides," Galib says.

The company's technology can be crucial for tracking KPIs and progress.

"When you're creating a Smart City, there are obviously objectives you set for what you consider to be a Smart City, but also there are ways to measure how well you're meeting those objectives," she adds.

Reality IMT

Houston-based Reality IMT is engaging the latest technology tools to digitize infrastructure.

"This really speaks to understanding our infrastructure and ways to make it safer and more efficient, and also understanding the data associated with that," says Galib.

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Houston scientists develop breakthrough AI-driven process to design, decode genetic circuits

biotech breakthrough

Researchers at Rice University have developed an innovative process that uses artificial intelligence to better understand complex genetic circuits.

A study, published in the journal Nature, shows how the new technique, known as “Combining Long- and Short-range Sequencing to Investigate Genetic Complexity,” or CLASSIC, can generate and test millions of DNA designs at the same time, which, according to Rice.

The work was led by Rice’s Caleb Bashor, deputy director for the Rice Synthetic Biology Institute and member of the Ken Kennedy Institute. Bashor has been working with Kshitij Rai and Ronan O’Connell, co-first authors on the study, on the CLASSIC for over four years, according to a news release.

“Our work is the first demonstration that you can use AI for designing these circuits,” Bashor said in the release.

Genetic circuits program cells to perform specific functions. Finding the circuit that matches a desired function or performance "can be like looking for a needle in a haystack," Bashor explained. This work looked to find a solution to this long-standing challenge in synthetic biology.

First, the team developed a library of proof-of-concept genetic circuits. It then pooled the circuits and inserted them into human cells. Next, they used long-read and short-read DNA sequencing to create "a master map" that linked each circuit to how it performed.

The data was then used to train AI and machine learning models to analyze circuits and make accurate predictions for how untested circuits might perform.

“We end up with measurements for a lot of the possible designs but not all of them, and that is where building the (machine learning) model comes in,” O’Connell explained in the release. “We use the data to train a model that can understand this landscape and predict things we were not able to generate data on.”

Ultimately, the researchers believe the circuit characterization and AI-driven understanding can speed up synthetic biology, lead to faster development of biotechnology and potentially support more cell-based therapy breakthroughs by shedding new light on how gene circuits behave, according to Rice.

“We think AI/ML-driven design is the future of synthetic biology,” Bashor added in the release. “As we collect more data using CLASSIC, we can train more complex models to make predictions for how to design even more sophisticated and useful cellular biotechnology.”

The team at Rice also worked with Pankaj Mehta’s group in the department of physics at Boston University and Todd Treangen’s group in Rice’s computer science department. Research was supported by the National Institutes of Health, Office of Naval Research, the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation, the American Heart Association, National Library of Medicine, the National Science Foundation, Rice’s Ken Kennedy Institute and the Rice Institute of Synthetic Biology.

James Collins, a biomedical engineer at MIT who helped establish synthetic biology as a field, added that CLASSIC is a new, defining milestone.

“Twenty-five years ago, those early circuits showed that we could program living cells, but they were built one at a time, each requiring months of tuning,” said Collins, who was one of the inventors of the toggle switch. “Bashor and colleagues have now delivered a transformative leap: CLASSIC brings high-throughput engineering to gene circuit design, allowing exploration of combinatorial spaces that were previously out of reach. Their platform doesn’t just accelerate the design-build-test-learn cycle; it redefines its scale, marking a new era of data-driven synthetic biology.”

Axiom Space wins NASA contract for fifth private mission, lands $350M in financing

ready for takeoff

Editor's note: This story has been updated to include information about Axiom's recent funding.

Axiom Space, a Houston-based space infrastructure company that’s developing the first commercial space station, has forged a deal with NASA to carry out the fifth civilian-staffed mission to the International Space Station.

Axiom Mission 5 is scheduled to launch in January 2027, at the earliest, from NASA’s Kennedy Space Center in Florida. The crew of non-government astronauts is expected to spend up to 14 days docked at the International Space Station (ISS). Various science and research activities will take place during the mission.

The crew for the upcoming mission hasn’t been announced. Previous Axiom missions were commanded by retired NASA astronauts Michael López-Alegría, the company’s chief astronaut, and Peggy Whitson, the company’s vice president of human spaceflight.

“All four previous [Axiom] missions have expanded the global community of space explorers, diversifying scientific investigations in microgravity, and providing significant insight that is benefiting the development of our next-generation space station, Axiom Station,” Jonathan Cirtain, president and CEO of Axiom, said in a news release.

As part of Axiom’s new contract with NASA, Voyager Technologies will provide payload services for Axiom’s fifth mission. Voyager, a defense, national security, and space technology company, recently announced a four-year, $24.5 million contract with NASA’s Johnson Space Center in Houston to provide mission management services for the ISS.

Axiom also announced today, Feb. 12, that it has secured $350 million in a financing round led by Type One Ventures and Qatar Investment Authority.

The company shared in a news release that the funding will support the continued development of its commercial space station, known as Axiom Station, and the production of its Axiom Extravehicular Mobility Unit (AxEMU) under its NASA spacesuit contract.

NASA awarded Axiom a contract in January 2020 to create Axiom Station. The project is currently underway.

"Axiom Space isn’t just building hardware, it’s building the backbone of humanity’s next era in orbit," Tarek Waked, Founding General Partner at Type One Ventures, said in a news release. "Their rare combination of execution, government trust, and global partnerships positions them as the clear successor-architect for life after the ISS. This is how the United States continues to lead in space.”

Houston edtech company closes oversubscribed $3M seed round

fresh funding

Houston-based edtech company TrueLeap Inc. closed an oversubscribed seed round last month.

The $3.3 million round was led by Joe Swinbank Family Limited Partnership, a venture capital firm based in Houston. Gamper Ventures, another Houston firm, also participated with additional strategic partners.

TrueLeap reports that the funding will support the large-scale rollout of its "edge AI, integrated learning systems and last-mile broadband across underserved communities."

“The last mile is where most digital transformation efforts break down,” Sandip Bordoloi, CEO and president of TrueLeap, said in a news release. “TrueLeap was built to operate where bandwidth is limited, power is unreliable, and institutions need real systems—not pilots. This round allows us to scale infrastructure that actually works on the ground.”

True Leap works to address the digital divide in education through its AI-powered education, workforce systems and digital services that are designed for underserved and low-connectivity communities.

The company has created infrastructure in Africa, India and rural America. Just this week, it announced an agreement with the City of Kinshasa in the Democratic Republic of Congo to deploy a digital twin platform for its public education system that will allow provincial leaders to manage enrollment, staffing, infrastructure and performance with live data.

“What sets TrueLeap apart is their infrastructure mindset,” Joe Swinbank, General Partner at Joe Swinbank Family Limited Partnership, added in the news release. “They are building the physical and digital rails that allow entire ecosystems to function. The convergence of edge compute, connectivity, and services makes this a compelling global infrastructure opportunity.”

TrueLeap was founded by Bordoloi and Sunny Zhang and developed out of Born Global Ventures, a Houston venture studio focused on advancing immigrant-founded technology. It closed an oversubscribed pre-seed in 2024.

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