After the floods from Hurricane Harvey totaled her car, Rahel Abraham wanted to find a solution. ClimaGuard/Facebook

Floodwaters from Hurricane Harvey seriously damaged about 600,000 vehicles in the Houston area, driving millions upon millions of dollars in auto insurance claims. Rahel Abraham's 2008 Infiniti G35 was among them.

Rather than merely moving on from the hurricane, though, Abraham — drawing upon her experience as an engineer in Houston's petrochemical industry — invented something that she foresaw shielding cars from the economic wrath of flooding.

Now, Abraham's brainchild forms the backbone of her Houston-based startup, ClimaGuard LLC. The next several weeks promise to be momentous for the business — Abraham will enter the 12-week DivInc business accelerator program in Austin in late August, and the company's first product is set to hit the market in early September.

ClimaGuard's waterproof, temperature-resistant, portable Temporary Protective Enclosure (TPE) can entirely cover a compact car, sedan, or midsize SUV. It comes in three sizes; the cost ranges from $349 to $499.

To protect a vehicle, someone sets a TPE on the ground, a driveway, or another flat surface, then drives the vehicle onto the bottom part of the product, and connects the bottom and top parts with the zipper. Abraham likens it to a clamshell preserving a pearl.

Once the vehicle is inside the TPE, it can be anchored with straps to a sturdy fixture. It's designed to withstand up to three feet of water and keep the vehicle from floating away.

One person can set up a TPE in less than five minutes, Abraham says.

She hopes to team up with auto insurers to offer discounts for policyholders that have a TPE. This, Abraham says, would spur more people to buy the product.

"My goal is not to make it to where it's an exclusive product — available only to those who can afford it — but I want to be able to help those who it would make even more of an economic impact for," Abraham says.

Among potential customers for the TPE are car owners, homeowners, small businesses, first-responder organizations, and nonprofit agencies, Abraham says. Other than vehicles, the product could protect valuables like antique pianos and restaurant gear, according to Abraham.

The sense of "helplessness and vulnerability" Abraham felt after her car was lost in Hurricane Harvey propelled her to devise ClimaGuard's TPE, she says, so that others might avoid enduring the sort of "stressful and traumatic" ordeal that she did.

Another catalyst: After hatching the idea for the TPE, Abraham learned that more than 41 million Americans live in federally designated flood zones, and that flooding is the costliest type of natural disaster in the U.S. and is forecast to occur more frequently. That research "validated my gut feeling," she says.

Abraham, a first-time entrepreneur, founded the bootstrapped startup in 2018, just a year after Harvey. Today, she's the only full-time employee of ClimaGuard. She holds a bachelor's in chemical engineering from the University of Texas at Austin and a master's degree in environmental engineering from the University of Houston.

Abraham says she hopes participating in the 12-week DivInc accelerator program in Austin will broaden her business network and hone her marketing skills. ClimaGuard was among 13 companies selected for this fall's DivInc group, which is sponsored by JPMorgan Chase.

DivInc aims to diversify the startup environment by offering workshops, mentoring, and business-strategy assistance to underrepresented entrepreneurs — people of color and women. The Austin-based nonprofit organization chooses participants through an application process that its program director, Brooke Turner, describes as being "extremely competitive" this year.

"It's tough being a developer or entrepreneur when no one looks like you when you walk into a room of other developers or entrepreneurs," DivInc co-founder Ashley Jennings told Crunchbase in 2017. "How can they feel that they fit in? So what we have now is an opportunity to create role models with this generation."
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Greentown Labs names Lawson Gow as its new Houston leader

head of hou

Greentown Labs has named Lawson Gow as its Head of Houston.

Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. He also recently served as managing partner at Houston-based investment and advisory firm Helium Capital. Gow is the son of David Gow, founder of Energy Capital's parent company, Gow Media.

According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role.

“I couldn’t be more excited to join Greentown at this critical moment for the energy transition,” Gow said in a news release. “Greentown has a fantastic track record of supporting entrepreneurs in Houston, Boston, and beyond, and I am eager to keep advancing our mission in the energy transition capital of the world.”

Gow has also held analyst, strategy and advising roles since graduating from Rice University.

“We are thrilled to welcome Lawson to our leadership team,” Georgina Campbell Flatter, CEO of Greentown Labs, added in the release. “Lawson has spent his career building community and championing entrepreneurs, and we look forward to him deepening Greentown’s support of climate and energy startups as our Head of Houston.”

Gow is the latest addition to a series of new hires at Greentown Labs following a leadership shakeup.

Flatter was named as the organization's new CEO in February, replacing Kevin Dutt, Greentown’s interim CEO, who replaced Kevin Knobloch after he announced that he would step down in July 2024 after less than a year in the role.

Greentown also named Naheed Malik its new CFO in January.

Timmeko Moore Love was named the first Houston general manager and senior vice president of Greentown Labs. According to LinkedIn, she left the role in January.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

fresh funding

Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.