GoExpedi, an e-commerce software company, represents Houston's tech and startup ecosystem on this year's Inc. 5000. Image courtesy of GoExpedi

In the latest edition of its roundup of fastest growing privately held companies, Inc. magazine has recognized dozens of Houston organizations.

Houston startup GoExpedi, an industrial supply chain and analytics company, is the highest ranking local tech company on the list. GoExpedi ranked No. 675 in the 2022 edition of Inc. 5000, with a 924 percent growth rate between 2018 and 2021.

"The team at GoExpedi is honored to rank number 675 among America's Fastest-Growing Private Companies on the Inc. 5000 Annual List," says Tim Neal, CEO of GoExpedi, in a news release. "GoExpedi has grown exponentially since launching in 2017 due to our forward-thinking and innovative supply chain solutions."

Real estate firm Disrupt Equity is the overall top Houston performer, and the sole Houston company to break the top 200 in the report. The company charted an impressive 2,975 percent growth rate between 2018 and 2021. The firm pushes complete multifamily real estate investment offerings that are earmarked as able to achieve and even exceed projections, clearly a safe haven in one of the biggest — and hottest — real estate markets in the entire nation.

Disrupt claims an impressive ROI for clients: The company boasts a "proven track record with over a dozen full cycle exits averaging over 36 percent annualized return to investors," director of investor relations, Tarek Moussa, tells CultureMap.

"We could not be more ecstatic to hear that Disrupt Equity has been announced as the fastest growing company in Houston by Inc 5000," says Feras Moussa, Disrupt's managing partner, in a statement. "We believe success in real estate, especially in today's economic environment, comes from being a great operator and having a strong team behind you. We believe this has been a large contributor to our success and helps us to continue to provide incredible passive real estate investment opportunities to our investors."

Speaking of real estate, another Houston firm performed well. Construction Concepts, which specializes in commercial design and build in Houston and Austin, ranked No. 497 overall, with 1,251 percent growth over three years. 5111 VENTURES, listed as a full-service real estate brokerage firm specializing in technology-driven residential and commercial sales and consulting services, was No. 558 with 1125 percent growth over three years.

In all, 468 Texas-based companies made this year’s Inc. 5000. Dallas-Fort Worth firms performed especially well:

  • No. 13 StaffDNA, Plano, 19,699 percent growth rate
  • No. 17 Blue Hammer Roofing, Dallas, 15,911 percent growth rate
  • No. 116 TimelyMD, Fort Worth, 3,852 percent growth rate
  • No. 142 Curis Functional Health, Farmers Branch, 3,380 percent growth rate
  • No. 148 SmartLight Analytics, Plano, 3,317 percent growth rate
  • No. 168 Digital Thrive, Dallas, 3,056 percent growth rate
  • No. 172 Forester Haynie, Dallas, 2,984 percent growth rate

Here are the other Texas companies appearing in the state’s top 20 and in the top 500 overall.

  • No. 60 AdOutreach, Austin, 6,052 percent growth rate
  • No. 62 Webforce, Austin, 6,009 percent growth rate
  • No. 117 Homestead Brands, Austin, 3,839 percent growth rate
  • No. 174 Disrupt Equity, Houston, 2,975 percent growth rate
  • No. 188 24HourNurse Staffing, Pittsburg, 2,801 percent growth rate
  • No. 201, Everly Health, Austin, 2,643 percent growth rate
  • No. 209, Texas Solar Integrated, San Antonio, 2,559 percent growth rate
  • No. 212, Apple Blvd Boutique, Frisco, 2,555 percent growth rate
  • No. 285 Element 26, Austin, 1,948 percent growth rate
  • No. 312 Boostlingo, Austin, 1,820 percent growth rate
  • No. 317 Cover Desk, Austin, 1,800 percent growth rate
  • No. 325 Canopy Management, Austin, 1,758 percent growth rate
  • No. 497 Construction Concepts, Houston, 1,251 percent growth rate

Companies on the 2022 Inc. 5000 are ranked by percentage growth in revenue from 2018 to 2021. To qualify for the list, a company must have been founded and been generating revenue by March 31, 2018. The company also must have been U.S.-based, privately held, for-profit, and independent as of December 31, 2021. The minimum revenue required for 2018 was $100,000; the minimum for 2021 was $2 million.

"The accomplishment of building one of the fastest-growing companies in the U.S., in light of recent economic roadblocks, cannot be overstated," says Scott Omelianuk, editor in chief of Inc. "Inc. is thrilled to honor the companies that have established themselves through innovation, hard work, and rising to the challenges of today."

A total of 90 Houston-area companies made the list last year, including Homestead Brands, Onit, GoCo.io, Velentium, Softeq, Poetic, Techwave, and more.

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This article originally ran on CultureMap. Steven Devadanam and Natalie Harms also contributed to this story.

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Houston scientist wins prestigious Pew Scholar award for brain cancer research

standout scholar

Christina Tringides, an assistant professor of materials science and nanoengineering at Rice University, is one of 21 scientists to win a prestigious Pew Biomedical Scholar award.

She is the first faculty member from Rice to win the distinction, which provides $300,000 over four years for advances in biomedicine, according to the university. The awards are granted to researchers who are in the first few years at the assistant professor level.

In Tringides’ case, the funding will support her innovative new method of modeling glioblastoma, a common and extremely aggressive form of brain cancer. Thanks to producing its own blood supply, glioblastoma spreads quickly, weaving tendrils of blighted tissue throughout the brain. Because of this, surgery is difficult and conventional therapies ineffective.

Understanding the way glioblastoma spreads is crucial to the search for a cure. Tringides is using hydrogels that mimic the brain’s extracellular matrix. Using cultures and a microscopic labyrinth, her team can see how the cancer spreads, bonds with neurons and changes cell wall activity. Essentially, Tringides has devised an intelligence test for tumors in hopes of learning how to outsmart them.

“As cancer crawls through the maze, we can look at how it is interacting with the neurons more and more, and measure how electrical activity is changing as a result,” she said in a news release from Rice.

Examining how cancer cells grow can reveal which conditional changes slow them down. Finding ways to alter the structure of brain matter in a way that makes it inhospitable to the cancer could lead to therapies that would impede growth or even reverse it. Using her custom-made ersatz brain maze makes it easier to observe changes than it would be in a patient’s brain.

“Imaging synapses is time-intensive ⎯ it can involve large data files that are hard to visualize, but if we know that the only place where we might have a synapse is this tiny 1-by-4-by-10 micron channel, it makes it much faster and reliable to image them,” Tringides said.

Born in Ames, Iowa, Tringides received her doctorate in biophysics from Harvard before joining Rice in 2024 through a Cancer Prevention and Research Institute of Texas (CPRIT) recruitment award.

Her research was also one of the first four projects to receive research awards through the Rice Brain Institute and TMC Neuro Collaboration Seed Grant Program.

Texas residents earn 11th highest income in U.S., says 2026 study

Money Matters

A new WalletHub study comparing income disparities across America has ranked Texas residents No. 11 on the list of states with the highest earning residents in the nation.

The report, "States Where People Have the Highest Income (2026)," analyzed U.S. Census Bureau income data in all 50 states and the District of Columbia. The report evaluated the average annual income of the top five percent, the median annual household income, and the average annual income of the bottom 20 percent of residents in every state, all adjusted for the cost of living.

The report's data revealed the top five percent of Texans, the highest earners, make $520,378 on average yearly after adjusting for the cost of living. That's the seventh-highest income among the top five percent of earners nationwide.

Meanwhile, the median annual income of a Texas household is just under $76,000. The bottom 20 percent of Texas residents make $17,651 a year, the report found.

For additional context, the latest data from the Federal Reserve shows an American household's median yearly income is about $83,700. WalletHub analyst Chip Lupo also found that the highest earning 10 percent of individuals in the U.S. earn over 12 times more than those in the lowest-earning 10 percent, based on the latest Census data.

"By measuring the income of various percentiles against a state's median income, we can better identify where income disparities are more prevalent, which could help us better understand why residents of certain states struggle more to make ends meet," said Lupo.

Virginia is the state where residents earn the highest income in the U.S., WalletHub said. Based on the report's findings, the top five percent of Virginians make $545,097 on average per year after adjusting for the cost of living. The median annual income of a Virginia household comes out to $95,339, and the bottom 20 percent of residents make $19,671 annually on average.

Conversely, West Virginia is the state where people have the lowest income in the U.S. A West Virginia household makes a median annual income of $56,610, the third-lowest nationally, and the bottom 20 percent of residents make $13,260 on average per year, which is the fifth-lowest in the nation. The top five percent of West Virginians make $372,218 on average per year.

The top 10 states where residents have the highest income are:

  • No. 1 – Virginia
  • No. 2 – New York
  • No. 3 – New Jersey
  • No. 4 – Washington
  • No. 5 – Connecticut
  • No. 6 – Utah
  • No. 7 – Colorado
  • No. 8 – Minnesota
  • No. 9 – Illinois
  • No. 10 – Massachusetts

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This article originally appeared on CultureMap.com.

23 Houston companies rank among America’s most future-ready businesses

future focused

By one measure, Spring-based tech giant Hewlett Packard Enterprises reigns as the most future-ready Houston-area company on the S&P 500 stock index.

HPE sits at No. 72 in a first-time ranking of the best S&P 500 companies for the future. Including HPE, 23 Houston-area companies appear on the list.

Published by The Wall Street Journal, the ranking was created by Bendable Labs for the WSJ Leadership Institute. It evaluates how S&P 500 companies stack up in six areas: AI readiness, innovation, talent readiness, financial fitness, resilience and agility. To be ranked, a company had to be part of the S&P 500 as of Dec. 31.

Among the six categories, HPE ranked highest for innovation (No. 30) among local companies. The WSJ didn’t say why HPE scored so well for innovation. However, the company stands out in this category thanks to:

  • Creation of the El Capitan and Frontier supercomputing systems
  • Research into photonic computing and quantum networking
  • Last year’s $14 billion acquisition of Juniper Networks, giving HPE an edge in AI-native networking
  • Establishment of the everything-as-a-service GreenLake hybrid cloud platform for data centers, colocation facilities and edge computing environments

In an interview with the Six Five podcast at HPE Discover 2025 in Las Vegas, CEO Antonio Neri said the company’s strategy is “basically founded on innovation, and that innovation drives shareholder value over the long term.”

While HPE fared well in the innovation category, it ranked toward the bottom for financial fitness. What’s behind the No. 430 ranking in the financial category? HPE’s low score likely reflects a debt-heavy acquisition strategy coupled with a historically low-margin hardware business.

Here’s the full list of the 23 Houston-area companies included in the ranking of the best companies for the future:

  • No. 72 Hewlett Packard Enterprise
  • No. 105 SLB
  • No. 120 Baker Hughes
  • No. 125 ConocoPhillips
  • No. 158 NRG Energy
  • No. 176 Targa Resources
  • No. 185 Chevron
  • No. 195 Halliburton
  • No. 223 Coterra Energy
  • No. 229 Waste Management
  • No. 235 Exxon Mobil
  • No. 250 Kinder Morgan
  • No. 257 Quanta Services
  • No. 276 CenterPoint Energy
  • No. 285 Sysco
  • No. 313 Occidental Petroleum
  • No. 318 Camden Property Trust
  • No. 333 EOG Resources
  • No. 365 LyondellBasell Industries
  • No. 373 Comfort Systems USA
  • No. 401 Crown Castle
  • No. 408 Phillips 66
  • No. 500 APA