Head honcho

Houston biopharmaceutical company brings on new CEO to grow company

A Houston biotech company has a new CEO and is ready for growth. Getty Images

With a veteran of the biopharmaceutical industry now aboard as its CEO and an executive at pharmaceutical giant AstraZeneca now serving on its board, Houston-based biopharmaceutical company Pulmotect Inc. is poised for progress.

In September, Dr. Colin Broom joined Pulmotect as CEO. He previously was CEO of Ireland-based Nabriva Therapeutics plc, a biopharmaceutical company that went public in 2015. During Broom's tenure at Nabriva, he helped develop the recently approved drug Xenleta, which treats bacterial pneumonia. Before that, he was chief scientific officer at Pennsylvania-based pharmaceutical company ViroPharma Inc., which Massachusetts-based Shire plc purchased for $4.2 billion in 2014.

Broom's hiring came on the heels of Kumar Srinivasan being named to Pulmotect's board of directors. Srinivasan is vice president of United Kingdom-based AstraZeneca and is its global head of business development and licensing for biopharmaceuticals R&D.

Researchers at MD Anderson Cancer Center and Texas A&M University invented Pulmotect's main product, PUL-042, which holds patents in nine countries. Pulmotect, founded in 2007, emerged from Houston's Fannin Innovation Studio, which nurtures early stage companies in the life sciences sector.

"Attracting such a highly regarded and proven CEO as Colin is a clear signal of the power and potential of Pulmotect's development program," Pulmotect's executive chairman, Leo Linbeck III, founder and chairman of Fannin, says in a release. "Under his leadership, I'm confident that we will advance our technology further into the clinic and closer to the marketplace. His addition is a real game-changer for the company."

Both Broom and Srinivasan are focusing on clinical trials for Pulmotect's PUL-042 product, an inhaled therapy that holds the potential to prevent or treat respiratory infections caused by bacteria, viruses, or fungi. The current Phase 2 trial is evaluating the effectiveness of PUL-042 in treating patients with mild chronic obstructive pulmonary disease (COPD) who've been exposed to a respiratory virus. The current trial is supposed to be followed by additional Phase 2 trials.

COPD, which affects 30 million Americans, is the No. 3 cause of death in the U.S., according to the COPD Foundation. Pulmotect says 40 percent of COPD-related costs could be avoided by preventing complications and hospitalizations, which typically result from COPD problems triggered by a bacterial or viral infection. PUL-042 could substantially decrease those complications, the company says.

Pulmotect seeks to gear PUL-042 toward patients with cancer who are undergoing chemotherapy, as their weakened immunity makes them highly susceptible to pneumonia, Broom says. If the product proves effective with those patients, then people at risk of developing respiratory infections also might benefit from it, including COPD patients and flu patients, he says.

To date, Pulmotect has raised more than $28 million in funding. That includes about $18 million in research grants, including a $7 million grant from the Cancer Prevention and Research Institute of Texas, as well as seven grants from the Small Business Innovation Research program.

Two of Pulmotect's three full-time employees work in Houston, and a team of consultants supports their work, Broom says. A small number of employees might be added during the current Phase 2 trial. Hiring would need to be ramped up if the Phase 2 trial demonstrates that PUL-042 works, he says.

Ambassadors get to experience events like Family Fun Day. Photo courtesy of Texas Children's Hospital

For the last 10 years, a special group of Houstonians have been walking the walk when it comes to helping one of the city's most revered institutions and changing lives every day.

Ambassadors for Texas Children's Hospital have been supporting patients through philanthropic donations and active engagement, and now you can, too.

The program has three goals: compassion, philanthropy, and advocacy. Just as Texas Children's strives to provide children and women with the best possible care, Ambassadors gain firsthand experience of the hospital's compassionate spirit and work tirelessly to embody this commitment in their actions.

They have given millions of dollars to help meet the hospital's needs, providing support where it will have the greatest impact, as well as standing and speaking up for patients through their own contributions and enlisting others in the cause.

Ambassadors also have the opportunity to attend exclusive, behind-the-scenes educational and social events to learn more about the patients they serve. This includes gatherings like Ambassadors On Call, which can range from luncheons that feature special guest lecturers and renowned health experts to question-and-answer sessions with leading scientists and physicians to behind-the-scenes tours of operating rooms and research facilities.

Family Fun Day is another special event for Ambassadors. This annual "party with a purpose" is a family-focused event where Ambassadors celebrate their work on behalf of Texas Children's. The day is filled with unique activities and lots of opportunities to meet new friends and spend time with old ones. To teach the next generation about philanthropy, the price of admission is one donated book.

To celebrate the successes of the year, Ambassadors gather at a member's home to share the spirit of the season. The holiday party also includes the presentation of the group's annual check to Texas Children's and the announcement of the coming year's philanthropic focus.

Ambassadors enjoy access to the hospital's navigation line services for assistance with referrals, appointments, and health and safety information for children — an invaluable resource for parents and grandparents alike.

For more information about becoming an Ambassador, visit texaschildrens.org/ambassadors or call 832-824-6900.

The holiday party includes the presentation of the group's annual check to the hospital. Photo courtesy of Texas Children's Hospital

With Ambassadors On Call, you gain access to behind-the-scenes tours and guest lecturers. Photo courtesy of Texas Children's Hospital