health-focused activewear

Houston entrepreneur designs clothing that benefits skin health

Emeline Kuhner-Stout, founder of Élastique Athletics, wanted to create a product that was easy to wear and benefitted lymphatic health. Photo courtesy of Élastique Athletics

A few years ago, Emeline Kuhner-Stout, a French ex-pat, was figuring out life as a new mom in a new city. She found her new life in Houston to be sedentary and all consumed with taking care of her baby. Her only time for herself were her daily trips to the gym, and she wanted to make it worth her while.

"There were so many more things I wanted to do for myself, and I just didn't have the time," Kuhner-Stout tells InnovationMap. "It would be so much more efficient if there was a way to combine [elements] to make products that would perform for us."

She noticed at this time that people were starting to care about what they wear to the gym, and she was also looking into the causes of cellulite. Kuhner-Stout and her husband, Myron, who's a patent attorney, started doing some research and found that there weren't any products that existed at the confluence of activewear and skincare.

Élastique Athletics was born to fill that need.

Creating a solution

Photo courtesy of Élastique Athletics

After deciding to tackle cellulite, Kuhner-Stout started doing her homework. She learned that cellulite was caused by poor lymphatic drainage and subsequent water retention.

"We did some research, and found that the best way to improve the appearance of your skin and move those fluids — because the cause [of cellulite] is really about those fluids that get trapped under your skin and cause a lot more negative effects other than skin appearance," Kuhner-Stout says.

She learned that exercise is the best move for improving lymphatic drainage, and another option is to do it manually through massaging and with compression. After around five years of research and development, Kuhner-Stout was able to release her first product for Élastique Athletics — a pair of leggings that have MicroPerle™ micro-massage beads in the compression leggings to massage the skin when worn.

Making space

Photo via instagram.com/elastiqueathletics

The L'Original legging launched online while Kuhner-Stout was working out of WeWork's Jones Building office. She started to realize that customers wanted to try the new type of legging on before they made the $220 investment, and WeWork didn't exactly have the try-on experience Kuhner-Stout wanted for her customers.

She opened the Élastique Athletics store in River Oaks Shopping District late last year and now hopes to use the space to bring women together, and Kuhner-Stout has had health and wellness experts in the space for events and workshops.

"I really want to build Élastique as a true wellness brand, and I think it's very important for us to interact with professionals who focus their energy and time on making women feel great," Kuhner-Stout says.

The new space is also about allowing customers to stay involved with Élastique.

"We want to turn our customers into advocates, and to do that, we have to be more than a product or brand," she says.

Growing her company

Photo courtesy of Élastique Athletics

Kuhner-Stout, who has funded her work by bootstrapping and a family and friends round, hopes to raise a seed round in the near future to continue her growth.

"We feel like we have enough data from our customers to do it right," Kuhner-Stout says on raising a round.

Élastique Athletics is also almost ready to launch its next product — a sports bra that is also optimized with the MicroPerle™ micro-massage bead technology. She also hopes to get her products into more physical spaces.

"These next few months, we are focusing on partnering with high-end spas," Kuhner-Stout says, adding that she wants people to think of her leggings more of a skincare treatment than just activewear.

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Building Houston

 
 

A Rice research team is tapping into materials science to better understand Alzheimer’s disease, a UH professor is developing a treatment for hereditary vision loss, and a BCM researcher is looking at stress and brain cancer. Photo by Gustavo Raskosky/Rice University

Research, perhaps now more than ever, is crucial to expanding and growing innovation in Houston — and it's happening across the city right under our noses.

In InnovationMap's latest roundup of research news, three Houston institutions are working on life-saving health care research thanks to new technologies.

Rice University scientists' groundbreaking alzheimer's study

Angel Martí (right) and his co-authors (from left) Utana Umezaki and Zhi Mei Sonia He have published their latest findings on Alzheimer’s disease. Photo by Gustavo Raskosky/Rice University

According to the Centers for Disease Control and Prevention, Alzheimer’s disease will affect nearly 14 million people in the U.S. by 2060. A group of scientists from Rice University are looking into a peptide associated with the disease, and their study was published in Chemical Science.

Angel Martí — a professor of chemistry, bioengineering, and materials science and nanoengineering and faculty director of the Rice Emerging Scholars Program — and his team have developed a new approach using time-resolved spectroscopy and computational chemistry, according to a news release from Rice. The scientists "found experimental evidence of an alternative binding site on amyloid-beta aggregates, opening the door to the development of new therapies for Alzheimer’s and other diseases associated with amyloid deposits."

Amyloid plaque deposits in the brain are a main feature of Alzheimer’s, per Rice.

“Amyloid-beta is a peptide that aggregates in the brains of people that suffer from Alzheimer’s disease, forming these supramolecular nanoscale fibers, or fibrils” says Martí in the release. “Once they grow sufficiently, these fibrils precipitate and form what we call amyloid plaques.

“Understanding how molecules in general bind to amyloid-beta is particularly important not only for developing drugs that will bind with better affinity to its aggregates, but also for figuring out who the other players are that contribute to cerebral tissue toxicity,” he adds.

The National Science Foundation and the family of the late Professor Donald DuPré, a Houston-born Rice alumnus and former professor of chemistry at the University of Louisville, supported the research, which is explained more thoroughly on Rice's website.

University of Houston professor granted $1.6M for gene therapy treatment for rare eye disease

Muna Naash, a professor at UH, is hoping her research can result in treatment for a rare genetic disease that causes vision loss. Photo via UH.edu

A University of Houston researcher is working on a way to restore sight to those suffering from a rare genetic eye disease.

Muna Naash, the John S. Dunn Endowed Professor of biomedical engineering at UH, is expanding a method of gene therapy to potentially treat vision loss in patients with Usher Syndrome Type 2A, or USH2A, a rare genetic disease.

Naash has received a $1.6 million grant from the National Eye Institute to support her work. Mutations of the USH2A gene can include hearing loss from birth and progressive loss of vision, according to a news release from UH. Naash's work is looking at applying gene therapy — the introduction of a normal gene into cells to correct genetic disorders — to treat this genetic disease. There is not currently another treatment for USH2A.

“Our goal is to advance our current intravitreal gene therapy platform consisting of DNA nanoparticles/hyaluronic acid nanospheres to deliver large genes in order to develop safe and effective therapies for visual loss in Usher Syndrome Type 2A,” says Naash. “Developing an effective treatment for USH2A has been challenging due to its large coding sequence (15.8 kb) that has precluded its delivery using standard approaches and the presence of multiple isoforms with functions that are not fully understood."

BCM researcher on the impact of stress

This Baylor researcher is looking at the relationship between stress and brain cancer thanks to a new grant. Photo via Andriy Onufriyenko/Getty Images

Stress can impact the human body in a number of ways — from high blood pressure to hair loss — but one Houston scientist is looking into what happens to bodies in the long term, from age-related neurodegeneration to cancer.

Dr. Steven Boeynaems is assistant professor of molecular and human genetics at Baylor College of Medicine. His lab is located at the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital, and he also is a part of the Therapeutic Innovation Center, the Center for Alzheimer’s and Neurodegenerative Diseases, and the Dan L Duncan Comprehensive Cancer Center at Baylor.

Recently, the Cancer Prevention and Research Institute of Texas, or CPRIT, awarded Boeynaems a grant to continue his work studying how cells and organisms respond to stress.

“Any cell, in nature or in our bodies, during its existence, will have to deal with some conditions that deviate from its ideal environment,” Boeynaems says in a BCM press release. “The key issue that all cells face in such conditions is that they can no longer properly fold their proteins, and that leads to the abnormal clumping of proteins into aggregates. We have seen such aggregates occur in many species and under a variety of stress-related conditions, whether it is in a plant dealing with drought or in a human patient with aging-related Alzheimer’s disease."

Now, thanks to the CPRIT funding, he says his lab will now also venture into studying the role of cellular stress in brain cancer.

“A tumor is a very stressful environment for cells, and cancer cells need to continuously adapt to this stress to survive and/or metastasize,” he says in the release.

“Moreover, the same principles of toxic protein aggregation and protection through protein droplets seem to be at play here as well,” he continues. “We have studied protein droplets not only in humans but also in stress-tolerant organisms such as plants and bacteria for years now. We propose to build and leverage on that knowledge to come up with innovative new treatments for cancer patients.”

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