Tomorrow, August 21, is World Entrepreneurs' Day, and it comes during a trying time for entrepreneurs everywhere. Here are three tips for business leaders operating during the pandemic. Photo via Getty Images

As company leaders approach the fourth quarter of 2020 and plan for 2021, many accept the fact that Houston's business landscape may look a bit different moving forward. Instead of the pandemic becoming a paralyzing force, new and eager business owners are committed to incorporating creative solutions.

These innovators have found ways to focus efforts to better serve customers in the transitioning economic landscape. The shift opens the door to new opportunity, and while the business outlook continues to evolve, some argue that times of crisis provide just as much, if not more, opportunity for entrepreneurs to find their footing. The past has shown that organizations can grow when faced with adversity and their resiliency in the earliest stages helps create a sturdy foundation.

According to the United States Bureau of Labor Statistics, twenty percent of small businesses fail within the first year, and by the tenth year, only about a third of businesses have survived. While these numbers may be intimidating to a new business owner, the measurements have proven consistent over time. This means success rates are less dependent upon the state of the economy and more dependent upon the creativity and drive of the entrepreneur leading the efforts.

Times of uncertainty and economic change bring focus to new obstacles, expose weaknesses in business structure and highlight the need for innovation. Strategic entrepreneurs can capitalize on these opportunities by introducing solutions that respond to the current reality consumers face. In honor of World Entrepreneurs' Day on August 21, below are steps to consider when launching a business during a time of crisis.

Plan for current conditions

It is always important for new business owners to plan for the future and be flexible enough to adjust them to the current environment. If a five-year plan is based on the premise of business returning to its pre-COVID-19 scale, the entrepreneur will likely face substantial challenges in the future.

Business plans should incorporate solutions to areas of weakness that have been brought to light by recent events. It may also be helpful to seek customer feedback early in the company's lifecycle to ensure audience opinion serves as a cornerstone in ongoing strategic development. Understanding if the business's premise will drive value and benefit consumers, even in difficult times, can help the organization prepare for future crises.

Identify gaps

In many ways, the pandemic identified business strategies that may no longer be relevant and provided insight into the economy's future. New entrepreneurs hold the advantage of witnessing what worked, what did not and applying the new knowledge to their plan.

The importance of flexibility, adaptable services, a strong digital brand presence and solid SEO practices all proved critical to a business's ability to remain both relevant and successful this year. When starting a company in times of economic uncertainty, identifying ways to bridge gaps and capitalize on windows of opportunity can help establish a competitive edge early on.

Seek out support

It is no surprise that, especially in the early stages, running a startup may be overwhelming. It is key for small business owners to feel comfortable asking for help and to seek out support early on. Consider joining business networks and local industry alliances to learn from others. Particularly in times of crisis and uncertainty, it can be beneficial to learn from seasoned professionals, as well as peers, and to welcome support from others who have found success during trying times.

Business support can be advantageous as well. While outsourcing may appear costly, the value of industry experts to assist with marketing strategy development, human resources and benefits, or financial management can be highly beneficial, especially in the development phase.

The early stages of an organization can make or break the success of a company, and though many questions surround the state of business during times of uncertainty, the entrepreneurial opportunity is still available for small business growth and success.

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Jill Chapman is a senior performance consultant with Houston-based Insperity, a leading provider of human resources and business performance solutions.

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Austin company to bring AI-powered school to The Woodlands

AI education

Austin-based Alpha School, which operates AI-powered private schools, is opening its first Houston-area location in The Woodlands.

The 8,000-square-foot school, scheduled to be ready for the 2026-27 academic year, initially will serve students in kindergarten through eighth grade. Alpha says the school will offer “open workshop spaces and innovative classrooms that support personalized instruction, core academics, leadership development, and real-world life skills.”

Alpha sets aside two hours each school day for the AI-driven, self-paced study of core subjects like math, reading and science. The rest of each school day consists of life-skills workshops focusing on topics such as leadership and financial literacy.

Alpha’s school in The Woodlands has begun accepting applications for the 2026-27 school year. Annual tuition costs $40,000.

“The Woodlands is one of the most dynamic, forward-thinking communities in Texas, and Alpha is proud to bring

an innovative educational model that complements its strong academic foundation,” says Rachel Goodlad, head

of expansion for Alpha.

Founded in 2014, Alpha School combines adaptive technology-driven instruction with immersive life-skills workshops. Its model emphasizes mastery-based learning in core subjects alongside development of communication, critical thinking, financial literacy and leadership skills. It operates more than 15 schools across the country.

Elsewhere in Texas, Alpha operates schools in Austin, Brownsville, Fort Worth and Plano. Alpha also operates 12 Texas Sports Academy campuses in Texas, including locations in Houston, Pearland and Richmond, along with a NextGen Academy esports school in Austin, a school for gifted students in Georgetown, and lower-cost Nova Academy campuses in Austin and Bastrop.

Alpha has fans and critics. While supporters tout students’ high achievement rates, detractors complain about the high tuition and the AI-influenced depersonalization of education.

“Students and our country need to be in relationship with other human beings,” Randi Weingarten, president of the American Federation of Teachers, a teachers union, tells The New York Times. “When you have a school that is strictly AI, it is violating that core precept of the human endeavor and of education.”

Alpha co-founder MacKenzie Price, a podcaster and social media influencer, doesn’t share Weingarten’s views.

“Parents and teachers: We need to embrace this change,” Price wrote after President Trump signed an executive order promoting AI in schools.

The Times notes that Alpha doesn’t employ AI as a tutor or a supplement. Rather, the newspaper says, AI is “the school’s primary educational driver to move students through academic content.”

Houston researcher secures $1.7M to develop drug for aggressive form of breast cancer

cancer research

A University of Houston researcher has joined a $3.2 million effort to develop a new drug designed to attack a cancer-driving protein commonly found in triple-negative breast cancer.

Triple-negative breast cancer (TNBC) is one of the most difficult-to-treat forms of cancer and accounts for 10 percent to 15 percent of all breast cancer cases. The disease gets its name because tumors associated with it test negative for estrogen receptors, progesterone receptors and excess HER2 protein, making it difficult to target. Due to this, TNBC is often treated with general chemotherapy, which can come with negative side effects and drug resistance, according to UH.

UH College of Pharmacy research associate professor Wei Wang is developing a drug that can target the disease more specifically. The drug will target MDM2, a protein often overproduced in TNBC that also contributes to faster tumor growth.

Wang is working on a team led by Wei Li, director of the University of Tennessee Health Science Center College of Pharmacy’s Drug Discovery Center. She has received $1.7 million to support the research.

Wang and UH professor of pharmacology and toxicology Ruiwen Zhang have discovered a compound that can break down MDM2. In early laboratory models, the compound has shown the ability to shrink tumors.

Wang and Zhang will focus on understanding how the treatment works and monitoring its effectiveness in models that closely mirror human disease.

“We will study how the drug targets MDM2 and evaluate the most promising drug candidates to determine effective dosing, understand how the drug behaves in the body, compare it with existing treatments and assess early safety,” Wang said in a news release.

Li’s team at the University of Tennessee will be working on the chemistry and drug design end of the project.

“This work could lead to an entirely new class of therapies for triple-negative breast cancer,” Li added in the release. “We’re hopeful that by directly removing the MDM2 protein from cancer cells, we can help more patients respond to treatment regardless of their tumor type.”