Through the Houston-based Muvve app, fitness fans can meet each other on the app or at curated events around town. Courtesy of Muvve

When Avi Ravishankar decided to train for a marathon in high school, he wanted to find a training buddy. He got lucky, and one found him: his classmate, Julian Se, took on the task.

"Julian decided he was going to train with me — he's a strong personality," Ravishankar says. "We started training, and to this day, we just became best friends from there."

Usually, finding fitness friends and training buddies isn't that easy — especially in a huge, spread out city of Houston. Ravishankar and Se turned their friendship into a business partnership to solve this problem. Houston-based Muvve is a mobile app that's mission is to connect fellow fitness enthusiasts across the city. The two came up with the idea as a way to merge their passions.

"The only idea we had was we wanted to have a startup with running," Ravishankar, co-founder of Muvve, says. "We loved running and tech, so we just wanted to find a way to bridge the gap there."

Ravishankar, a Rice University alumnus, says he took his idea to Owl Spark, an early stage accelerator on campus, and they just started asking people about their pain points when it came to working out.

"The big two things that we found were accountability and motivation," he says. "Out of 100 people, I would say all 100 people said that."

Ravishankar, who worked for six years in engineering at Oxy, says that these pain points are actually pretty inherent to individual sports.

"Intrinsic motivation is hard to find, especially in individual sports, like running, cycling, or yoga," he says. "Whereas, in team sports, like basketball or volleyball, you have the team to train with and motivate you."

The app, which launched in May of 2018, acts like a network for fitness lovers — just like a dating app would connect potential romantic partners. Dating apps, actually, were a big influence on Ravishankar, he says.

"I fell in love with dating apps. It was this mind-blowing idea for me of how many people you can connect with — even if it's not for dating," he says. "The amount of people I have met just through technology always blows my mind. There's so much power in it."

Through his experience as an instructor at Black Swan Yoga, Ravishankar also realized boutique fitness studios needed a place to market their events to a wider audience. This gave Ravishankar an idea of a way to bridge the gap between different fitness studios around town via the app.

"For us the goal is to have all of these events and activities to go and meet like-minded people," he says.

Muvve's goal is to have these managed market events that are curated to ensure quality, rather than the hit or miss aspect of existing platforms.

"For me the curation aspect makes for a better experience," Ravishankar says.

Now, Muvve is focused on growing its user base from 4,500 to 10,000 users by summer. Simultaneously, the company is hoping to launch its first seed round of funding, and then using its funds and its network to launch into Austin by summer.

Ravishankar says finding potential investors has been the most challenging aspect.

"There's no money in Houston for a fitness tech startup," he says. "That space isn't really respected. For me, it's kind of a trickling effect. If there's no money in it, there's no one really to help you because they don't have a vested interest."

While funding has been daunting, Ravishankar says he's had some success in hiring out his team of developers, despite the uphill battle of hiring tech talent in Houston.

"There's hidden talent, but it's not obvious talent," Ravishankar says. "I think that people get discouraged by hiring in Houston because of that."


Muvve is harnessing the power of social media and digital networks to bridge the gap between fitness lovers across the city. Courtesy of Muvve

Houston-based Kanthaka is the Uber or Lyft of personal training, and has recently expanded into the Austin market. Courtesy of Kanthaka

Get on-demand personal training from Houston-based app

Fitting in fitness

As a busy lawyer who traveled heavily for work, Sylvia Kampshoff found her workouts were often overlooked as she went from city to city, a casualty of long hours and a busy schedule. And, even though she did have a membership to a national gym with privileges at any of its locations, she hated the feeling of always being sold something and disliked that both the trainers and managers she worked with took very little interest in her personal needs and fitness goals.

She wanted something that allowed her to exercise with someone on her own schedule, and with people who valued customer service. That's how the idea for Kanthaka was born.

The app uses location technology similar to that of ride sharing apps to allow users to book training sessions with certified personal trainers, all of whom are heavily vetted and background checked by Kampshoff and her team.

"Many trainers at gyms or who work privately aren't certified," she says. "And that was important to me, that we have professionals who understand training and the body. And making sure our clients felt safe was a huge priority for me. We interview every trainer personally to ensure they not only meet our standards but also share our goals."

App users can select a trainer who will lead them in a Pilates, yoga, boxing, general training, or a pre- or post-natal workout. They select their location, as well as the date and they want to schedule a session. They can book a single session for $42 for a 45-minute session or $50 for an hour session or purchase a package of six or 12 workouts. There's no long-term commitment — although Kampshoff says that some clients are asking for a monthly subscription option — and the process is designed to be easy and user friendly. Trainers will arrive at a client's home, office, or their preferred gym, providing the gym allows outside trainers to work there.

The app launched in Houston in 2017 and then in Austin this fall. Over the last year, Kampshoff — who left the legal profession to concentrate on Kanthaka's success — says she's learned a lot about the market and her own preconceptions.

"I figured it was going to be business travelers who used it, people who were like me when I was doing all that travel," she says. "But it turns out that we're seeing people use it who want to schedule a session just like any other appointment. Many of our clients are women, who value the rigorous vetting process we have for our trainers."

In addition to vetting the trainers and confirming their certifications with the National Academy for Sports Medicine or the American Council on Exercise, each trainer is reviewed by app users, to help others determine whether that person would be a good fit for their needs. Kanthaka allows users to "favorite" trainers, and book them again, and user testimonials tout Kanthaka's easy of use and great training team.

In addition to individual users who find the app via social media or internet searches, Kampshoff has developed partnerships with hotels and apartments around Houston. Kanthaka provides personal training services to guests at the Post Oak Hotel, and Hanover apartment properties list the app as a feature for its residents.

As she continues to grow the business and expand in other cities, Kampshoff is excited to see others buying into her concept of fitness.

"There is a culture behind Kanthaka. It's about health and fitness, but also achieving the lifestyle you want that allows you to feel better and live in a more positive way."

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New Houston biotech co. developing capsules for hard-to-treat tumors

biotech breakthroughs

Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

How Houston's innovation sector fared in 2025 Texas legislative session

That's a Wrap

The Greater Houston Partnership is touting a number of victories during the recently concluded Texas legislative session that will or could benefit the Houston area. They range from billions of dollars for dementia research to millions of dollars for energy projects.

“These wins were only possible through deep collaboration, among our coalition partners, elected officials, business and community leaders, and the engaged members of the Partnership,” according to a partnership blog post. “Together, we’ve demonstrated how a united voice for Houston helps drive results that benefit all Texans.”

In terms of business innovation, legislators carved out $715 million for nuclear, semiconductor, and other economic development projects, and a potential $1 billion pool of tax incentives through 2029 to support research-and-development projects. The partnership said these investments “position Houston and Texas for long-term growth.”

Dementia institute

One of the biggest legislative wins cited by the Greater Houston Partnership was passage of legislation sponsored by Sen. Joan Huffman, a Houston Republican, to provide $3 billion in funding over 10 years for the Dementia Prevention and Research Institute of Texas. Voters will be asked in November to vote on a ballot initiative that would set aside $3 billion for the new institute.

The dementia institute would be structured much like the Cancer Prevention and Research Institute of Texas (CPRIT), a state agency that provides funding for cancer research in the Lone Star State. Since its founding in 2008, CPRIT has awarded nearly $3.9 billion in research grants.

“By establishing the Dementia Prevention and Research Institute of Texas, we are positioning our state to lead the charge against one of the most devastating health challenges of our time,” Huffman said. “With $3 billion in funding over the next decade, we will drive critical research, develop new strategies for prevention and treatment, and support our healthcare community. Now, it’s up to voters to ensure this initiative moves forward.”

More than 500,000 Texans suffer from some form of dementia, including Alzheimer’s disease, according to Lt. Gov. Dan Patrick.

“With a steadfast commitment, Texas has the potential to become a world leader in combating [dementia] through the search for effective treatments and, ultimately, a cure,” Patrick said.

Funding for education

In the K-12 sector, lawmakers earmarked an extra $195 million for Houston ISD, $126.7 million for Cypress-Fairbanks ISD, $103.1 million for Katy ISD, $80.6 million for Fort Bend ISD, and $61 million for Aldine ISD, the partnership said.

In higher education, legislators allocated:

     
  • $1.17 billion for the University of Houston College of Medicine, University of Texas Health Science Center at Houston, UT MD Anderson Cancer Center, and Baylor College of Medicine
  • $922 million for the University of Houston System
  • $167 million for Texas Southern University
  • $10 million for the Center for Biotechnology at San Jacinto College.

Infrastructure

In the infrastructure arena, state lawmakers:

     
  • Approved $265 million for Houston-area water and flood mitigation projects, including $100 million for the Lynchburg Pump Station
  • Created the Lake Houston Dredging and Maintenance District
  • Established a fund for the Gulf Coast Protection District to supply $550 million for projects to make the coastline and ship channel more resilient

"Nuclear power renaissance"

House Bill 14 (HB 14) aims to lead a “nuclear power renaissance in the United States,” according to Texas Gov. Greg Abbott’s office. HB 14 establishes the Texas Advanced Nuclear Energy Office, and allocates $350 million for nuclear development and deployment. Two nuclear power plants currently operate in Texas, generating 10 percent of the energy that feeds the Electric Reliability Council Texas (ERCOT) power grid.

“This initiative will also strengthen Texas’ nuclear manufacturing capacity, rebuild a domestic fuel cycle supply chain, and train the future nuclear workforce,” Abbott said in a news release earlier this year.

One of the beneficiaries of Texas’ nuclear push could be Washington, D.C.-based Last Energy, which plans to build 30 micro-nuclear reactors near Abilene to serve power-gobbling data centers across the state. Houston-based Pelican Energy Partners also might be able to take advantage of the legislation after raising a $450 million fund to invest in companies that supply nuclear energy services and equipment.

Reed Clay, president of the Texas Nuclear Alliance, called this legislation “the most important nuclear development program of any state.”

“It is a giant leap forward for Texas and the United States, whose nuclear program was all but dead for decades,” said Clay. “With the passage of HB 14 and associated legislation, Texas is now positioned to lead a nuclear renaissance that is rightly seen as imperative for the energy security and national security of the United States.”

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A version of this article first appeared on EnergyCapitalHTX.com.

Microsoft partners with Rice University's OpenStax on AI teaching tool

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Rice University’s OpenStax and Microsoft are partnering to integrate the nonprofit’s content with the tech giant’s AI innovation, known as Learning Zone.

“At OpenStax, our mission is to make an amazing education accessible to all,” Richard G. Baraniuk, founder and director of OpenStax, said in a news release. “That’s why we’re excited to integrate our trustworthy, peer-reviewed content with Microsoft’s AI technology through the Microsoft Learning Zone. Together, we aim to help more instructors and their students access engaging, effective learning experiences in new and dynamic ways. We also share a strong commitment to the thoughtful and responsible application of AI to better ensure all learners can succeed.”

OpenStax is a provider of affordable instructional technologies and is also one of the world’s largest publishers of open educational resources (OER).

Microsoft Learning Zone promises to provide educators and students with “responsible AI technology and peer-reviewed educational content to support learning” on Microsoft Copilot+ PCs. Microsoft Learning Zone works by utilizing on-device AI to generate interactive lessons for students, and its integration with OpenStax content means educators can rely on OpenStax’s digital library of 80 openly licensed titles.

The goal is for educators to create effective and engaging learning experiences safely, thereby bypassing the need to source and vet content independently. Included is a library of ready-to-use lessons, opportunity for immediate feedback and differentiated learning. Educators will maintain control of instructional content and pedagogical strategies and will be able to update or edit lessons or activities prior to sharing them with students.

Other tools included in the Microsoft Learning Zone are additional languages, reading coaching, public speaking help, math and reading progress, and a partnership with the online quiz platform Kahoot!

OpenStax resources have been reported as used across 153 countries, and this current collaboration combines the power and potential of responsible AI usage in education with content that has been utilized by 13,569 K-12 schools and 71 percent of U.S. colleges and universities, according to Rice.

“Through our partnership with OpenStax, we’re combining the power of on-device AI in Copilot+ PCs with OpenStax’s trusted and diverse peer-reviewed content to help educators quickly create high-quality, personalized, engaging lessons,” Deirdre Quarnstrom, vice president of Microsoft Education, added in the news release. “We’re excited about how this collaboration will empower classrooms globally.”