It's WeWork Labs' second Texas location — the first opened last fall in Dallas. Courtesy of WeWork

WeWork is betting on the Bayou City as it plans to open up WeWork Labs in its downtown Houston coworking space. The early-stage program will provide up to 30 startups with mentorship and resources coordinated by its partner organization, Alice, an entrepreneurial digital resource with Texas ties.

"At Alice, our research has shown that entrepreneurs are hungry for guidance that gets into the nitty gritty: 'What next step should I take?' 'How exactly do I go about fundraising?' 'What should my to-do list look like if customer acquisition is my No. 1 goal?'' says Carolyn Rodz, CEO and co-founder of Alice, in a release. "We're really excited to collaborate with WeWork Labs to bring these answers to their members through both programming and online support."

WeWork Labs launches this month in the WeWork Jones Building at 708 Main St. It's the second Texas location — Dallas' location opened last fall. Prices for the program begin at $300 a month for entrepreneurs, and the program does not take equity in the participating startups.

Leading the program is Labs Manager Carlos Estrada and WeWork Managing Director Emily Keeton — both have long careers in innovation and startups across the country. Keeton was among the original founders of Station Houston and is based in Houston. A Houston native, Estrada most recently launched Roots Venture Group, which focused on growing startups within the agricultural and rural industries.

"As the fourth largest city, Houston is in a unique position to launch high-impact startups," Estrada says in the release. "We see WeWork Labs in Houston as a tremendous platform for innovation, as our founder-focused approach to supporting early-stage startups will nurture and accelerate the work of entrepreneurs to scale their solutions to today's biggest challenges. We look forward to growing our community here and bringing together key players across the region to drive innovation throughout Houston, the state of Texas, and beyond."

WeWork Labs launched around a year ago and now has over 30 locations worldwide. The program hopes to connect the dots for startups and the corporate world by providing education, mentorship, and a global network. The downtown Houston location will operate alongside WeWork's Veterans in Residence program and the Flatiron School campus.

"We are incredibly honored to have WeWork Labs join our community to support an already growing network of startups within the city of Houston," says Nathan Lenahan, WeWork's general manager for Texas, in the release. "Housing WeWork Labs with both our Flatiron School campus and Veterans in Residence program is a true testament to the innovative community we strive to create within our spaces. We are thrilled to expand on our commitment to Houston and its entrepreneurs and can't wait to see the impact we can have together on it's diverse community."

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.