You can search Houston's top BBQ spots by a wide range of criteria. Courtesy of Houston BBQ Guide

Anew website wants to help Houstonians eat better barbecue. Created by the founders of the Houston BBQ Festival, the Houston BBQ Guide offers readers the ability to search for restaurants based on a wide range of criteria, including location, parking, and whether a restaurant is likely to sell out of food.

The editors of the guide, led by Houston Chronicle barbecue columnist J.C. Reid, have selected the 28 initial entries with an eye on small, family-run businesses that aim "to provide a quality product and experience on a consistent basis." Entries include both historic barbecue joints like Lenox Bar-B-Q and Pizzitola's Bar-B-Que as well as spots that have earned recognition on Texas Monthly's list of the state's 50 best such as CorkScrew BBQ and The Pit Room.

Each entry includes details about a restaurant's ownership and pitmaster, noteworthy dishes, and a brief video tour. The website also includes essays about the history of Houston's barbecue restaurants and other relevant topics.

As an "about the guide" section notes, people who want to eat barbecue may not know where to find it. By breaking things does geographically, the guide offers diners the opportunity to discover new places or be prompted to visit old favorites that aren't necessarily included in media-generated lists of the "best" barbecue restaurants.

"I like to think of it as a guide for everyday barbecue fans," Reid said in a statement.

The guide also offers an alternative to crowd-sourced review websites as well as the responses one gets on social media when a request for a restaurant near Sugar Land might be met with a suggestion to drive to Tomball — well-intentioned, surely, but not very helpful.

The guide will add new entries in time. For example, Feges BBQ's original Greenway Plaza location is listed but its newly opened Spring Branch outpost isn't (yet). A separate guide to barbecue pop-ups is already in the works, and the editors also tout the possibility of expanding to other Texas cities.

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This article originally ran on CultureMap.

Kids can know their grandparents and great-grandparents a little better. Keeping Families Connected/Facebook

Sweet new Texas-based website lets you record a final goodbye for loved ones

FAMILY LEGACIES

Anew North Texas startup helps soothe the sting of losing loved ones by allowing them to leave behind an entirely different kind of heirloom. A Sweet Goodbye is a new online service that lets people record messages that can be accessed and enjoyed by family and friends after they're gone.

Fort Worth-based founder Rich Hollander, who worked for Radio Shack/Tandy Corporation in the area for more than 25 years, got the idea about a year ago during a reflective moment.

"I was sitting in synagogue, a quiet time when you contemplate things," he says. "During those times, I talk to my parents — who are both gone — and my late brother, and about 15 other people who have passed away. On this particular morning, I was talking to my mom. I knew what she was telling me, but I couldn't hear her voice. I thought, 'I wish I could just push a button and hear her voice,' but there's nothing I could do about that."

While it's too late for Hollander to hear his mother's voice, he says, he wanted to provide such a service for other people. He also says he wanted to make the process as simple and as painless as possible.

"You go to our website and click on a button that says, 'I want to make a recording.' Before that you prepare a little bit. You figure out what you want to say, and you figure out who you want to send the message to. You get their email address, and we ask you to give us two trusted advisers so they can tell us when you passed away, and then you just record your message, and that's it."

The message customers record is hosted on the cloud, and it's all audio based. Your loved one will hear it after you die, as many times as they would like. There is no video option, and messages can last a maximum of five minutes long. According to Hollander, this is by design rather than due to technical limitations.

"We thought about our target customers; Baby Boomers and their parents don't want to see themselves," he says. "They don't like the idea of recording a video. And people don't want to listen for more than five minutes. You can say a lot in that amount of time."

Some people choose to pass down secret family recipes or record tales from their youth, the company says.

Realizing that people can also use phones and other home devices to make recordings, Hollander made A Sweet Goodbye inexpensive, accessible, and convenient. He says there are other options for similar services on the market, but they are "much more complex" and "much more expensive," costing up to $8 per month, compared to his company's one-time fee.

"You can listen to it a thousand times from your computer or your phone," he says. "You can have your children listen to it. They can listen to their great grandma's voice. For $25, it's a bargain."

Hollander himself uses the service.

"I have two adult daughters in their 40s," he says. "One lives here, one lives in New Zealand. My message to them is something like, 'If you pushed this button, you are probably having a bad day, and just need my voice of reassurance. So, understand that I'm up here in heaven, and I'm looking after you guys, and tomorrow will be a better day than today.' They can push that button and hear that message whenever and wherever they want."

While A Sweet Goodbye is simple to use, there is an emotional hurdle in getting started.

"The hard part is making the first message," Hollander says. "Because it's coming to grips with the fact that you are not going to be around forever, and neither is your mom. But it is cathartic. For me, the second message was extremely easy to make."

The site has just launched and is now available for anyone to access. On Veterans Day (November 11), A Sweet Goodbye will provide one free service for active duty members in the United States military. Later, they will do another giveaway for nurses and first responders. Follow their Facebook page for updates.

"It's our way of doing something nice for the world," Hollander says.

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This article originally ran on CultureMap.

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Axiom Space-tested cancer drug advances to clinical trials

mission critical

A cancer-fighting drug tested aboard several Axiom Space missions is moving forward to clinical trials.

Rebecsinib, which targets a cancer cloning and immune evasion gene, ADAR1, has received FDA approval to enter clinical trials under active Investigational New Drug (IND) status, according to a news release. The drug was tested aboard Axiom Mission 2 (Ax-2) and Axiom Mission 3 (Ax-3). It was developed by Aspera Biomedicine, led by Dr. Catriona Jamieson, director of the UC San Diego Sanford Stem Cell Institute (SSCI).

The San Diego-based Aspera team and Houston-based Axiom partnered to allow Rebecsinib to be tested in microgravity. Tumors have been shown to grow more rapidly in microgravity and even mimic how aggressive cancers can develop in patients.

“In terms of tumor growth, we see a doubling in growth of these little mini-tumors in just 10 days,” Jamieson explained in the release.

Rebecsinib took part in the patient-derived tumor organoid testing aboard the International Space Station. Similar testing is planned to continue on Axiom Station, the company's commercial space station that's currently under development.

Additionally, the drug will be tested aboard Ax-4 under its active IND status, which was targeted to launch June 25.

“We anticipate that this monumental mission will inform the expanded development of the first ADAR1 inhibitory cancer stem cell targeting drug for a broad array of cancers," Jamieson added.

According to Axiom, the milestone represents the potential for commercial space collaborations.

“We’re proud to work with Aspera Biomedicines and the UC San Diego Sanford Stem Cell Institute, as together we have achieved a historic milestone, and we’re even more excited for what’s to come,” Tejpaul Bhatia, the new CEO of Axiom Space, said in the release. “This is how we crack the code of the space economy – uniting public and private partners to turn microgravity into a launchpad for breakthroughs.”