Houston OTC chairman sees an increasing effect of digital tech ahead of the 50th anniversary

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Wafik Beydoun has served on the board of OTC for almost a decade. Courtesy of Beydoun

Wafik Beydoun has been on the board of the Houston Offshore Technology Conference — and has served as chairman for the past two years. As he prepares to pass the baton after this year's event, he's reflected on how much the conference has changed — namely due to new innovation and technologies.

"The rising tide of the digital revolution is lifting us all — not only OTC or the industry — and it's lifting us at an exponential rate," Beydoun tells InnovationMap. "Digital is moving now exponentially, whether we want it to or not, we're benefitting from it."

OTC takes place at NRG Park from May 6 to 9. Beydoun shares his observations and advice on how innovation and startups have effected change at the 50-year-old conference.

InnovationMap: What's going to differentiate this year's conference from previous years?

Wafik Beydoun: This year is very special because we are celebrating the 50th birthday of OTC. The first event was held in May of 1969. Last year it was the 50th event, so these two years are very unique. Last year, we had an opening ceremony, and we will have that again this year — that's different from OTCs in the past.

The most important change you'll see is the amount of papers on offshore renewables — it's something the board wanted to test and show that the industry is being more aware in this area. What I mean when I say offshore renewables is mostly offshore wind, but there's also energy from waves and gas hydrates — another form of gas trapped under ice in the subsea. These are things we have had in the past few years, but this year we have 14 sessions on marine renewables.

IM: What sort of new technologies (machine learning, IOT, AI, etc.) are you excited about seeing grow its presence at OTC?

WB: The way the technologies are impacting is it can go from drilling to monitoring remotely. More and more platforms in difficult conditions are reducing the number of people involved. There are already talks about unmanned platforms offshore. On safety in general, digital and AI immersion are able to help train people faster and without injuring themselves.

IM: How have startups been represented at the conference?

WB: We recognize that startups are adding a lot of oxygen into OTC. We need that for different reasons. For one, they bring in innovation in energy. Also with this kind of digital area, we have a lot of startups coming from Silicon Valley that want to innovate in the energy domain, and OTC can be that space where we can invite them to help us in our challenges.

IM: How has innovation and technology affected the conference specifically over the years?

WB: The conference is the place where you have all the specialists come and talk about their projects — it attracts all those who have an exciting story to tell, and it could be in innovation. And they bring their tool or technology into the exhibition. In 1969 at OTC, you could see the suit we'd put humans in to go under water. Now, you can see the robots that explore the seafloor.

IM: How has innovation and technology affected the conference specifically over the years?

WB: Register for the Rice Alliance Startup Roundup event. You have the opportunity to invest or meet face-to-face these 50 startups on the rise. The second thing you should attend is the Spotlight on the New Technology Award. Based on these technologies, you can have a feel of what's the leading edge of technology for the industry as presented by exhibitors. If an entrepreneur wants to see what's new and bringing money, attending this will show him or her what companies want that new technology.

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Portions of this interview have been edited.

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Greentown Labs names Lawson Gow as its new Houston leader

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Greentown Labs has named Lawson Gow as its Head of Houston.

Gow is the founder of The Cannon, a coworking space with seven locations in the Houston area, with additional partner spaces. He also recently served as managing partner at Houston-based investment and advisory firm Helium Capital. Gow is the son of David Gow, founder of Energy Capital's parent company, Gow Media.

According to Greentown, Gow will "enhance the founder experience, cultivate strategic partnerships, and accelerate climatetech solutions" in his new role.

“I couldn’t be more excited to join Greentown at this critical moment for the energy transition,” Gow said in a news release. “Greentown has a fantastic track record of supporting entrepreneurs in Houston, Boston, and beyond, and I am eager to keep advancing our mission in the energy transition capital of the world.”

Gow has also held analyst, strategy and advising roles since graduating from Rice University.

“We are thrilled to welcome Lawson to our leadership team,” Georgina Campbell Flatter, CEO of Greentown Labs, added in the release. “Lawson has spent his career building community and championing entrepreneurs, and we look forward to him deepening Greentown’s support of climate and energy startups as our Head of Houston.”

Gow is the latest addition to a series of new hires at Greentown Labs following a leadership shakeup.

Flatter was named as the organization's new CEO in February, replacing Kevin Dutt, Greentown’s interim CEO, who replaced Kevin Knobloch after he announced that he would step down in July 2024 after less than a year in the role.

Greentown also named Naheed Malik its new CFO in January.

Timmeko Moore Love was named the first Houston general manager and senior vice president of Greentown Labs. According to LinkedIn, she left the role in January.

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This article originally appeared on our sister site, EnergyCapitalHTX.com.

Houston foundation grants $27M to support Texas chemistry research

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Houston-based The Welch Foundation has doled out $27 million in its latest round of grants for chemical research, equipment and postdoctoral fellowships.

According to a June announcement, $25.5 million was allocated for the foundation's longstanding research grants, which provide $100,000 per year in funding for three years to full-time, regular tenure or tenure-track faculty members in Texas. The foundation made 85 grants to faculty at 16 Texas institutions for 2025, including:

  • Michael I. Jacobs, assistant professor in the chemistry and biochemistry department at Texas State University, who is investigating the structure and thermodynamics of intrinsically disordered proteins, which could "reveal clues about how life began," according to the foundation.
  • Kendra K. Frederick, assistant professor in the biophysics department at The University of Texas Southwestern Medical Center, who is studying a protein linked to Parkinson’s disease.
  • Jennifer S. Brodbelt, professor in chemistry at The University of Texas at Austin, who is testing a theory called full replica symmetry breaking (fullRSB) on glass-like materials, which has implications for complex systems in physics, chemistry and biology.

Additional funding will be allocated to the Welch Postdoctoral Fellows of the Life Sciences Research Foundation. The program provides three-year fellowships to recent PhD graduates to support clinical research careers in Texas. Two fellows from Rice University and Baylor University will receive $100,000 annually for three years.

The Welch Foundation also issued $975,000 through its equipment grant program to 13 institutions to help them develop "richer laboratory experience(s)." The universities matched funds of $352,346.

Since 1954, the Welch Foundation has contributed over $1.1 billion for Texas-nurtured advancements in chemistry through research grants, endowed chairs and other chemistry-related ventures. Last year, the foundation granted more than $40.5 million in academic research grants, equipment grants and fellowships.

“Through funding basic chemical research, we are actively investing in the future of humankind,” Adam Kuspa, president of The Welch Foundation, said the news release. “We are proud to support so many talented researchers across Texas and continue to be inspired by the important work they complete every day.”

New Houston biotech co. developing capsules for hard-to-treat tumors

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Houston company Sentinel BioTherapeutics has made promising headway in cancer immunotherapy for patients who don’t respond positively to more traditional treatments. New biotech venture creation studio RBL LLC (pronounced “rebel”) recently debuted the company at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.

Rima Chakrabarti is a neurologist by training. Though she says she’s “passionate about treating the brain,” her greatest fervor currently lies in leading Sentinel as its CEO. Sentinel is RBL’s first clinical venture, and Chakrabarti also serves as cofounder and managing partner of the venture studio.

The team sees an opportunity to use cytokine interleukin-2 (IL-2) capsules to fight many solid tumors for which immunotherapy hasn't been effective in the past. “We plan to develop a pipeline of drugs that way,” Chakrabarti says.

This may all sound brand-new, but Sentinel’s research goes back years to the work of Omid Veiseh, director of the Rice Biotechnology Launch Pad (RBLP). Through another, now-defunct company called Avenge Bio, Veiseh and Paul Wotton — also with RBLP and now RBL’s CEO and chairman of Sentinel — invested close to $45 million in capital toward their promising discovery.

From preclinical data on studies in mice, Avenge was able to manufacture its platform focused on ovarian cancer treatments and test it on 14 human patients. “That's essentially opened the door to understanding the clinical efficacy of this drug as well as it's brought this to the attention of the FDA, such that now we're able to continue that conversation,” says Chakrabarti. She emphasizes the point that Avenge’s demise was not due to the science, but to the company's unsuccessful outsourcing to a Massachusetts management team.

“They hadn't analyzed a lot of the data that we got access to upon the acquisition,” explains Chakrabarti. “When we analyzed the data, we saw this dose-dependent immune activation, very specific upregulation of checkpoints on T cells. We came to understand how effective this agent could be as an immune priming agent in a way that Avenge Bio hadn't been developing this drug.”

Chakrabarti says that Sentinel’s phase II trials are coming soon. They’ll continue their previous work with ovarian cancer, but Chakrabarti says that she also believes that the IL-2 capsules will be effective in the treatment of endometrial cancer. There’s also potential for people with other cancers located in the peritoneal cavity, such as colorectal cancer, gastrointestinal cancer and even primary peritoneal carcinomatosis.

“We're delivering these capsules into the peritoneal cavity and seeing both the safety as well as the immune activation,” Chakrabarti says. “We're seeing that up-regulation of the checkpoint that I mentioned. We're seeing a strong safety signal. This drug was very well-tolerated by patients where IL-2 has always had a challenge in being a well-tolerated drug.”

When phase II will take place is up to the success of Sentinel’s fundraising push. What we do know is that it will be led by Amir Jazaeri at MD Anderson Cancer Center. Part of the goal this summer is also to create an automated cell manufacturing process and prove that Sentinel can store its product long-term.

“This isn’t just another cell therapy,” Chakrabarti says.

"Sentinel's cytokine factory platform is the breakthrough technology that we believe has the potential to define the next era of cancer treatment," adds Wotton.

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