Wafik Beydoun has served on the board of OTC for almost a decade. Courtesy of Beydoun

Wafik Beydoun has been on the board of the Houston Offshore Technology Conference — and has served as chairman for the past two years. As he prepares to pass the baton after this year's event, he's reflected on how much the conference has changed — namely due to new innovation and technologies.

"The rising tide of the digital revolution is lifting us all — not only OTC or the industry — and it's lifting us at an exponential rate," Beydoun tells InnovationMap. "Digital is moving now exponentially, whether we want it to or not, we're benefitting from it."

OTC takes place at NRG Park from May 6 to 9. Beydoun shares his observations and advice on how innovation and startups have effected change at the 50-year-old conference.

InnovationMap: What's going to differentiate this year's conference from previous years?

Wafik Beydoun: This year is very special because we are celebrating the 50th birthday of OTC. The first event was held in May of 1969. Last year it was the 50th event, so these two years are very unique. Last year, we had an opening ceremony, and we will have that again this year — that's different from OTCs in the past.

The most important change you'll see is the amount of papers on offshore renewables — it's something the board wanted to test and show that the industry is being more aware in this area. What I mean when I say offshore renewables is mostly offshore wind, but there's also energy from waves and gas hydrates — another form of gas trapped under ice in the subsea. These are things we have had in the past few years, but this year we have 14 sessions on marine renewables.

IM: What sort of new technologies (machine learning, IOT, AI, etc.) are you excited about seeing grow its presence at OTC?

WB: The way the technologies are impacting is it can go from drilling to monitoring remotely. More and more platforms in difficult conditions are reducing the number of people involved. There are already talks about unmanned platforms offshore. On safety in general, digital and AI immersion are able to help train people faster and without injuring themselves.

IM: How have startups been represented at the conference?

WB: We recognize that startups are adding a lot of oxygen into OTC. We need that for different reasons. For one, they bring in innovation in energy. Also with this kind of digital area, we have a lot of startups coming from Silicon Valley that want to innovate in the energy domain, and OTC can be that space where we can invite them to help us in our challenges.

IM: How has innovation and technology affected the conference specifically over the years?

WB: The conference is the place where you have all the specialists come and talk about their projects — it attracts all those who have an exciting story to tell, and it could be in innovation. And they bring their tool or technology into the exhibition. In 1969 at OTC, you could see the suit we'd put humans in to go under water. Now, you can see the robots that explore the seafloor.

IM: How has innovation and technology affected the conference specifically over the years?

WB: Register for the Rice Alliance Startup Roundup event. You have the opportunity to invest or meet face-to-face these 50 startups on the rise. The second thing you should attend is the Spotlight on the New Technology Award. Based on these technologies, you can have a feel of what's the leading edge of technology for the industry as presented by exhibitors. If an entrepreneur wants to see what's new and bringing money, attending this will show him or her what companies want that new technology.

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Portions of this interview have been edited.

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Houston digital health platform Koda lands strategic investment

money moves

Houston-based advance care planning platform Koda Health has added another investor to the lineup.

The company secured a strategic investment for an undisclosed amount from UPMC Enterprises, the commercialization arm of the University of Pittsburgh Medical Center. The funding is part of Koda's oversubscribed series A funding round that closed in October, according to a release.

"UPMC Enterprises’ investment is a meaningful signal, not just to Koda, but to the broader market," Dr. Desh Mohan, chief medical officer and co-founder of Koda Health, said in the news release. "It validates that health systems are ready to invest in infrastructure that makes advance care planning work the way it should: proactively, at scale, and with the human support that these conversations require. Having UPMC Enterprises as a strategic investor puts us in a unique position to prove what's possible."

Koda has raised $14 million to date, according to a representative from the company. Its series A round was led by Evidenced, with participation from Mudita Venture Partners, Techstars and the Texas Medical Center last year. At the time, the company said the funding would allow it to scale operations and expand engineering, clinical strategy and customer success. The company described the round as a "pivotal moment," as it had secured investments from influential leaders in the healthcare and venture capital space.

Koda Health, which was born out of the TMC's Biodesign Fellowship in 2020, saw major growth last year, as well, and now supports more than 1 million patients nationwide through partnerships with Cigna Healthcare, Privia Health, Guidehealth, Sentara, UPMC and Memorial Hermann Health System.

The company integrated its end-of-life care planning platform with Dallas-based Guidehealth in April 2025 and with Epic Systems in July 2025. It also won the 2025 Houston Innovation Award in the Health Tech Business category. Read more here.

New 'living pharmacy' biotech company launches out of Rice venture studio

fighting cancer

Rice University’s biotech venture studio RBL LLC has launched a new “living pharmacy” company, Duracyte, designed to make cancer treatment easier on patients.

Backed by an up to $45 million Advanced Research Projects Agency for Health (ARPA-H) award, Duracyte aims to commercialize implantable biohybrid pharmacy devices that are designed to produce therapeutic proteins inside the human body around the clock, replacing the need for regular injections and infusions for some cancer patients.

The company’s main platform is its Hybrid Advanced Molecular Manufacturing Regulator (HAMMR), a rechargeable, implantable device that can sense biological signals, monitor tumor environments and adjust therapeutic output in real time. HAMMR has wireless communication capabilities, which allow patients and clinicians to remotely monitor results through an app every five minutes and make changes to treatment plans without a hosptial visit. Additionally, the device can generate its own oxygen supply, which is key for the therapeutic cells’ survival.

“Biologic medicines such as monoclonal antibodies, cytokines and metabolic regulators already account for a significant share of modern therapeutics, but the way we deliver them today often requires frequent injections or infusions that can be demanding for patients and lead to inconsistent drug levels,” Daniel Anderson, MIT professor and co-founder of Duracyte, said in a news release. “Our vision is to enable a continuous, stable therapy by producing these medicines directly inside the body, which could improve treatment consistency, reduce side effects and ultimately transform how biologic therapies are delivered across many diseases.”

Duracyte’s first clinical trial is slated to begin by the end of 2026 and will focus on recurrent ovarian cancer. The Phase I study will build upon existing work on encapsulated cytokine pharmacy technology, and the company hopes that within a few years this treatment can reach clinical application.

The development of Duracyte is supported by ARPA-H's Targeted Hybrid Oncotherapeutic Regulation (THOR) project, which supports a multidisciplinary research consortium co-led by Omid Veiseh, a professor of bioengineering at Rice. The consortium also includes others at Rice, The University of Texas MD Anderson Cancer Center, Stanford University, Carnegie Mellon University, Northwestern University and the University of Houston, plus industry collaborators like Chicago-based CellTrans.

“What we are building is the culmination of years of progress in cell engineering, biomaterials and implantable device technology,” Veiseh added in the release. “By combining these advances with real-time sensing and adaptive drug delivery, we are working with the support of RBL to create a true ‘living pharmacy’ that can deliver continuous, precisely controlled biologic therapies and fundamentally change how these treatments reach patients.”

RBL launched in 2024 and is based out of Houston’s Texas Medical Center Helix Park. Duracyte is the third company launched by RBL, including Sentinel BioTherapeutics, a clinical-stage immunotherapy company developing localized cytokine therapies for solid tumors, and SteerBio, a regenerative medicine company targeting lymphedema.

“Duracyte exemplifies the kind of breakthrough that Houston’s ecosystem is built to produce,” Paul Wotton, managing partner of RBL LLC and co-founder of Duracyte, added in the release. “With world-class clinical infrastructure, exceptional engineering talent and initiatives like the Texas Biotech Task Force driving alignment across industry, investment and talent, this region is uniquely positioned to move the most ambitious ideas in medicine from concept to patient, faster than anywhere else.”