Houston OTC chairman sees an increasing effect of digital tech ahead of the 50th anniversary

Featured Innovator

Wafik Beydoun has served on the board of OTC for almost a decade. Courtesy of Beydoun

Wafik Beydoun has been on the board of the Houston Offshore Technology Conference — and has served as chairman for the past two years. As he prepares to pass the baton after this year's event, he's reflected on how much the conference has changed — namely due to new innovation and technologies.

"The rising tide of the digital revolution is lifting us all — not only OTC or the industry — and it's lifting us at an exponential rate," Beydoun tells InnovationMap. "Digital is moving now exponentially, whether we want it to or not, we're benefitting from it."

OTC takes place at NRG Park from May 6 to 9. Beydoun shares his observations and advice on how innovation and startups have effected change at the 50-year-old conference.

InnovationMap: What's going to differentiate this year's conference from previous years?

Wafik Beydoun: This year is very special because we are celebrating the 50th birthday of OTC. The first event was held in May of 1969. Last year it was the 50th event, so these two years are very unique. Last year, we had an opening ceremony, and we will have that again this year — that's different from OTCs in the past.

The most important change you'll see is the amount of papers on offshore renewables — it's something the board wanted to test and show that the industry is being more aware in this area. What I mean when I say offshore renewables is mostly offshore wind, but there's also energy from waves and gas hydrates — another form of gas trapped under ice in the subsea. These are things we have had in the past few years, but this year we have 14 sessions on marine renewables.

IM: What sort of new technologies (machine learning, IOT, AI, etc.) are you excited about seeing grow its presence at OTC?

WB: The way the technologies are impacting is it can go from drilling to monitoring remotely. More and more platforms in difficult conditions are reducing the number of people involved. There are already talks about unmanned platforms offshore. On safety in general, digital and AI immersion are able to help train people faster and without injuring themselves.

IM: How have startups been represented at the conference?

WB: We recognize that startups are adding a lot of oxygen into OTC. We need that for different reasons. For one, they bring in innovation in energy. Also with this kind of digital area, we have a lot of startups coming from Silicon Valley that want to innovate in the energy domain, and OTC can be that space where we can invite them to help us in our challenges.

IM: How has innovation and technology affected the conference specifically over the years?

WB: The conference is the place where you have all the specialists come and talk about their projects — it attracts all those who have an exciting story to tell, and it could be in innovation. And they bring their tool or technology into the exhibition. In 1969 at OTC, you could see the suit we'd put humans in to go under water. Now, you can see the robots that explore the seafloor.

IM: How has innovation and technology affected the conference specifically over the years?

WB: Register for the Rice Alliance Startup Roundup event. You have the opportunity to invest or meet face-to-face these 50 startups on the rise. The second thing you should attend is the Spotlight on the New Technology Award. Based on these technologies, you can have a feel of what's the leading edge of technology for the industry as presented by exhibitors. If an entrepreneur wants to see what's new and bringing money, attending this will show him or her what companies want that new technology.

------

Portions of this interview have been edited.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Rice launches 'brain economy' initiative at World Economic Forum

brain health

Rice University has launched an initiative that will position “brain capital” as a key asset in the 21st century.

Rice rolled out the Global Brain Economy Initiative on Jan. 21 at the World Economic Forum in Davos, Switzerland.

“This initiative positions brain capital, or brain health and brain skills, at the forefront of global economic development, particularly in the age of artificial intelligence,” the university said in a news release.

The Rice-based initiative, whose partners are the University of Texas Medical Branch in Galveston and the Davos Alzheimer’s Collaborative, aligns with a recent World Economic Forum and McKinsey Health Institute report titled “The Human Advantage: Stronger Brains in the Age of AI,” co-authored by Rice researcher Harris Eyre. Eyre is leading the initiative.

“With an aging population and the rapid transformation of work and society driven by AI, the urgency has never been greater to focus on brain health and build adaptable human skills—both to support people and communities and to ensure long-term economic stability,” says Amy Dittmar, a Rice provost and executive vice president for academic affairs.

This initiative works closely with the recently launched Rice Brain Institute.

In its first year, the initiative will establish a global brain research agenda, piloting brain economy strategies in certain regions, and introducing a framework to guide financial backers and leaders. It will also advocate for public policies tied to the brain economy.

The report from the McKinsey Health Institute and World Economic Forum estimates that advancements in brain health could generate $6.2 trillion in economic gains by 2050.

“Stronger brains build stronger societies,” Eyre says. “When we invest in brain health and brain skills, we contribute to long-term growth, resilience, and shared prosperity.”

Rice Alliance and the Ion leader Brad Burke to retire this summer

lasting legacy

Brad Burke—a Rice University associate vice president who leads the Ion District’s Rice Alliance for Technology and Entrepreneurship and is a prominent figure in Houston’s startup community—is retiring this summer after a 25-year career at the university.

Burke will remain at the Rice Alliance as an adviser until his retirement on June 30.

“Brad’s impact on Rice extends far beyond any single program or initiative. He grew the Rice Alliance from a promising campus initiative into one of the most respected university-based entrepreneurship platforms,” Rice President Reginald DesRoches said in a news release.

During Burke’s tenure, the Rice Business School went from unranked in entrepreneurship to The Princeton Review’s No. 1 graduate entrepreneurship program for the past seven years and a top 20 entrepreneurship program in U.S. News & World Report’s rankings for the past 14 years.

“Brad didn’t just build programs — he built an ecosystem, a culture, and a reputation for Rice that now resonates around the world,” said Peter Rodriguez, dean of the business school. “Through his vision and steady leadership, Rice became a place where founders are taken seriously, ideas are rigorously supported, and entrepreneurship is embedded in the fabric of the university.”

One of Burke’s notable achievements at Rice is the creation of the Rice Business Plan Competition. During his tenure, the competition has grown from nine student teams competing for $10,000 into the world’s largest intercollegiate competition for student-led startups. Today, the annual competition welcomes 42 student-led startups that vie for more than $1 million in prizes.

Away from Rice, Burke has played a key role in cultivating entrepreneurship in the energy sector: He helped establish the Energy Tech Venture Forum along with Houston Energy and Climate Startup Week.

Furthermore, Burke co-founded the Texas University Network for Innovation and Entrepreneurship in 2008 to bolster the entrepreneurship programs at every university in Texas. In 2016, the Rice Alliance assumed leadership of the Global Consortium of Entrepreneurship Centers.

In 2023, Burke received the Trailblazer Award at the 2023 Houston Innovation Awards and was recognized by the Deshpande Foundation for his contributions to innovation and entrepreneurship in higher education.

“Working with an amazing team to build the entrepreneurial ecosystem at Rice, in Houston, and beyond has been the privilege of my career,” Burke said in the release. “It has been extremely gratifying to hear entrepreneurs say our efforts changed their lives, while bringing new innovations to market. The organization is well-positioned to help drive exponential growth across startups, investors, and the entrepreneurial ecosystem.”

Starting April 15, John “JR” Reale Jr. will serve as interim associate vice president at Rice and executive director of the Rice Alliance. He is managing director of the alliance. Reale is co-founder of the Station Houston startup hub and a startup investor. He was also recently named director for startups and investor engagement at the Ion.

“The Rice Alliance has always been about helping founders gain advantages to realize their visions,” Reale said. “Under Brad’s leadership, the Rice Alliance has become a globally recognized platform that is grounded in trust and drives transformational founder outcomes. My commitment is to honor what Brad has built and led while continuing to serve our team and community, deepen relationships and deliver impact.”

Burke joined the Houston Innovators Podcast back in 2022. Listen to the full interview here.

Houston team uses CPRIT funding to develop nanodrug for cancer immunotherapy

cancer research

With a relative five-year survival rate of 50 percent, pancreatic cancer is a diagnosis nobody wants. At 60 percent, the prognosis for lung cancer isn’t much rosier. That’s because both cancers contain regulatory B cells (Bregs), which block the body’s natural immunity, making it harder to fight the enemies within.

Newly popular immunotherapies in a category known as STING agonists may stimulate natural cancer defenses. However, they can also increase Bregs while simultaneously causing significant side effects. But Wei Gao, assistant professor of pharmacology at the University of Houston College of Pharmacy, may have a solution to that conundrum.

Gao and her team have developed Nano-273, a dual-function drug, packaged in an albumin-based particle, that boosts the immune system to help it better fight pancreatic and lung cancers. Gao’s lab recently received a $900,000 grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to aid in fueling her research into the nanodrug.

“Nano-273 both activates STING and blocks PI3Kγ—a pathway that drives Breg expansion, while albumin nanoparticles help deliver the drug directly to immune cells, reducing unwanted side effects,” Gao said in a press release. “This approach reduces harmful Bregs while boosting immune cells that attack cancer, leading to stronger and more targeted anti-tumor responses.”

In studies using models of both pancreatic and lung cancers, Nano-273 has shown great promise with low toxicity. Its best results thus far have involved using the drug in combination with immunotherapy or chemotherapy.

With the CPRIT funds, Gao and her team will be able to charge closer to clinical use with a series of important steps. Those include continuing to test Nano-273 alongside other drugs, including immune checkpoint inhibitors. Safety studies will follow, but with future patients in mind, Gao will also work toward improving her drug’s production, making sure that it’s safe and high-quality every time, so that it is eventually ready for trials.

Gao added: “If successful, this project could lead to a new type of immunotherapy that offers lasting tumor control and improved survival for patients with pancreatic and lung cancers, two diseases that urgently need better treatments."

View All Listings