Companies with resources to spare should step up to help support small and minority-owned businesses. Photo via Getty Images

It's clear that the pandemic continues to negatively impact many businesses, and chief among them small, minority-owned businesses. In fact, a study from late last year revealed that minority-owned organizations have been hit disproportionately hard – Black business owners experienced a 41 percent drop in business activity, while Latinx business activity dropped by 35 percent and Asian business activity dropped 26 percent.

Of course, COVID-19 is not the only obstacle that small and minority-owned businesses face. They are also contending with systemic social and economic injustices, civil and social unrest, as well as environmental events. In fact, the pandemic has further spotlighted these ongoing inequities in our communities.

In Houston, nearly 30 percent of startup companies are minority-owned, and studies indicate that Black neighborhoods have driven the majority of start-up growth during the pandemic. These small businesses and their owners have been in survival mode, using their skills, creativity, resources and capacities to keep their doors open and their businesses profitable — but this heavy burden should not fall on them alone.

After all, small businesses are the backbone of our economy. When they don't make it, our nation as a whole suffers: skyrocketing unemployment rates, reduced consumer spending and less optimistic long-term forecasts for all businesses, among other effects. But when they succeed, we all succeed.

Companies with resources to spare should step up to help support small and minority-owned businesses — and that's why last year Comcast created its initiative, Comcast RISE, to help these businesses resolve their challenges and find long-term success.

As part of the first wave of RISE — which stands for "Representation, Investment, Strength and Empowerment" — we gave eligible minority-owned small businesses located in Houston (and in four other U.S. cities severely impacted by COVID-19) the chance to apply for direct grants of $10,000. More than 700 small businesses received these grants, including more than 200 businesses based in the Houston area. Now, the second round of applications for RISE grants is open, and 100 lucky applicants will be chosen to each receive $10,000.

Two local businesses have already experienced the positive impact that these grants can provide. Ashley Gomez, 132 Design partner – a brand and web design company for small businesses – used their business' RISE grant to invest in technology and professional development for the staff. Since then, 132 Design has seen a 30 percent increase in revenue. Meanwhile, Cori Xiong, owner of the Houston-area staple Mala Sichuan Bistro, was able to pay off her extra business expenses associated with the pandemic, as well as invest in publicity and marketing efforts for her storefronts.

Here's what you need to know if you're a small business owner interested in applying for a grant. If your minority-owned business is eligible — that is, at least 51 percent minority-owned, independently owned and operated, registered as a business in the U.S., in operation for more than a year, and located in Harris or Fort Bend county— simply fill out the form on the Comcast RISE website between October 1 and 14, 2021.

We, at Comcast, are deeply committed to helping drive change and bolster the process of correcting social and economic injustices. The Comcast RISE program helps meaningfully impact and support the small businesses that are shaping our communities. At the end of the day, our economy's success is just part of the equation. It's on all of us to ensure equity, diversity, and inclusion for our communities.

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Vince Margiotta is the vice president at Comcast Business.

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Houston researchers report promising first in-human trial for implantable cancer therapy

cancer breakthrough

When it comes to cancer remedies, the treatment can be as challenging for the body as its cause. But what if immunotherapy could be localized? That’s precisely what a Houston team may soon make a reality.

Rice University researchers, in partnership with MD Anderson Cancer Center, recently published their findings from the first in-human trial of an implantable cancer-fighting treatment in the journal Clinical Cancer Research. The paper details testing of AVB-001, encapsulated cells engineered to release interleukin-2 (IL-2)—a naturally occurring signaling protein that boosts immunity—in the peritoneal cavities of 14 patients. The goal is to avoid the toxicity usually experienced with less targeted treatments, as well as find a solution to IL-2s’ abbreviated half-lives.

“Traditional IL-2 therapy has shown potent antitumor activity, but its clinical use has been limited by severe side effects and delivery challenges,” Omid Veiseh, director of the Rice Biotech Launch Pad, professor of bioengineering at Rice and a senior author on the study, said in a press release. “This platform allows us to localize and sustain cytokine exposure directly where tumors reside while minimizing systemic toxicity.”

Serous ovarian carcinoma is especially well-suited to the use of AVB-001 because it tends to spread throughout the abdomen. After a minimally invasive laparoscopic procedure, patients implanted with the cells were noted to tolerate the treatment well. Half of the enrolled patients’ cancer was stabilized, with several among them reporting extended signs of benefit. No maximum tolerated dose was reached and there were no life-threatening events tied to the study.

If that sounds like less-than-earth-shaking results, this is only the beginning. The capsules were implanted for about one week because IL-2 activity drops off after that. The researchers now know that further testing should include either higher levels, repeated doses, or a combination thereof, in order to create stronger advances.

The team has already made early headway on this next step. Preclinical studies in nonhuman primates were not only tolerated well, but without added toxicity, the apes had consistent pharmacological effects.

“This is a foundational step,” Veiseh explained. “We now have evidence that the platform is safe, biologically active and potentially scalable. The next phase is optimizing dosing and exploring combination therapies to unlock its full clinical potential.”

The combination would also include a checkpoint inhibitor, which might improve AVB-001’s tumor-fighting power. “What is exciting is that we are not just delivering a drug, we are programming a microenvironment,” added Dr. Amir Jazaeri, professor of gynecologic oncology at MD Anderson, member of the Rice Biotech Launch Pad’s clinical advisory board and a senior author on the study. “This opens the door to combination strategies that could amplify immune responses in ways that have not been feasible before.”

Houston startup raises $6M to scale home-based healthcare platform

fresh funding

As healthcare systems race to expand care beyond hospitals and into the home, investors are placing bigger bets on the infrastructure needed to make that shift possible.

This month, Rosarium Health announced it has raised $6 million in seed funding led by Kalos Ventures, with participation from ResilienceVC, Rock Health Capital, Symphonic Capital, Black Tech Nations Ventures and others.

The investment will help the Houston-based startup continue to build its platform, which features a national network of 800-plus clinicians and 3,000-plus contractors to coordinate home accessibility upgrades and modifications for seniors and people living with disabilities.

For founder and CEO Cameron Carter, the company’s mission grew out of firsthand caregiving experiences.

“From my own personal caregiving experiences, I realized that the benefits exist on paper, but not in reality,” Carter said in a news release. “Families are being left to figure out the paperwork and installations all on their own, which shouldn’t be how this works.”

While Medicare Advantage and Medicaid plans have expanded coverage for home-based services and accessibility modifications, the logistics behind delivering those services often remain fragmented.

Rosarium’s platform coordinates the entire process, from clinical assessments and referrals to contractor management, documentation, reimbursement and installation.

“A clinician can document that a home isn’t safe and a plan can approve a benefit, but there’s no one that’s responsible for making sure the work actually gets done,” Carter says. “We built the missing piece.”

The company was founded in 2021 as Rose Health and was a 2023 participant in the Texas Medical Center’s Accelerator for HealthTech program. It has scaled quickly, building a network of more than 800 clinicians and 3,000 contractors across 34 states.

Rosarium is currently in-network for 1.2 million Medicare and Medicaid lives, with projected coverage expected to reach nearly 4 million by the end of the year, according to the release.

“We’re excited to back Cameron because he and the team at Rosarium are building the infrastructure healthcare needs right now to make the home a safe and comfortable place of care,” Kate Ballinger, investor at Kalos Ventures, added in the release.

As part of the recent investment, Ballinger will join Rosarium’s board of directors.

With eyes on the future, Rosarium plans to grow its partnerships with Medicaid and Medicare Advantage plans, including CalViva and Community Health Plan of Imperial Valley, strengthening its presence in California while expanding access to underserved communities.

Additionally, Carter predicts that home-based healthcare will be part of a broader transformation happening across the industry.

“There’s a growing recognition that health outcomes are shaped by what happens in the home,” he said in the release. “The future of healthcare isn’t just treating people after something goes wrong. It’s creating environments that help prevent those problems in the first place.”