Houston program buoys promising cancer research with live-saving innovation

act-ing now

The Texas Medical Center's ACT program is making sure the most-promising cancer research makes it to its life-saving commercialization stage. Photo via tmc.edu

How do you bring promising cancer research to the masses? TMC Innovation's Accelerator for Cancer Therapeutics was established with that question in mind.

Funded by a $5 million grant from CPRIT, or the Cancer Prevention and Research Institute of Texas, in 2019 and in collaboration with the Gulf Coast Consortia and the University of Texas Medical Branch, the first cohort began their intensive work in 2021. The deadline to join the next cohort is October 13.

Since its inception, ACT has seen the forming of 19 companies — two of which have been awarded CPRIT seed grants, along with four in contention for one this year — as well as $92 million in dilutive funding and $10 million in non-dilutive funding.

“We’ve recruited investigators and companies from the breadth and width of the state of Texas, so all the way from Lubbock to Galveston from Dallas to the Rio Grande Valley,” Ahmed AlRawi, program manager, tells InnovationMap. “We've had an amazing set of investigators who have gone through the program — 56 teams to be precise.”

AlRawi says that the first pillar of the program is education. To that end, the cohort works with entrepreneurs in residence like Michael Torres. Best known as the co-founder of ReCode Therapeutics, Torres says that one of his greatest passions lies in translating science into medicines. ReCode is a genetic medicines company that is currently clinical-stage. It’s raised more than $300 million in the last two years, certainly something to which scientist-entrepreneurs earlier in their careers would aspire.

A longtime resident of Dallas, Torres moved his family to Houston last year, calling it “the place to be for cancer startups in Texas.”

Initially, says Torres, Houston wasn’t on his radar. But thanks to a call from ACT external advisor Dan Hargrove, Torres realized that the city might be a fit for him and his goals.

“I wanted to find a project that I could help support, sort of take my experience as a cofounder and help guide the next great startup within the ecosystem,” he says.

Torres and AlRawi agree that the biggest successes to come out of ACT so far include March Biosciences, a company from the first cohort, which is focused on developing CAR-T cell strategies to help combat hematological cancers; CPRIT fundee, OmniNano Pharmaceuticals, which uses patented nanotechnology to co-deliver a pair of therapeutical agents to solid tumors; and the latest, CrossBridge Bio.

Part of the most recent cohort, Torres has joined Drs. Kyoji Tsuchikama and Zhiqiang An as the last company’s CEO. To that end, he’s partnered with the world-class researchers out of UT Health Houston to build a next-generation antibody drug conjugate company that he believes will produce “better and safer and more effective drugs than what's currently on the market today.”

All the more reason that Torres he’s glad to have moved to Houston at what he calls “a really exciting time.” He’s thankful for the Texas Medical Center and the relationships it fosters. “We're all sort of aligning on creating a sustainable biotech ecosystem,” he says. And the next big cancer fighting company may well emerge from ACT.

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10+ can't-miss Houston business and innovation events for October

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Editor's note: Houston's October calendar is packed with informative and impactful events—plus a few fun ones, too. From the fourth annual Tejano Tech Summit to the first-ever Ion Family Tech Festival, here's what not to miss and how to register. Please note: this article may be updated to include additional event listings.

Oct. 3 — Houston Methodist Joy in Medicine Initiative Symposium

The Houston Methodist Joy in Medicine Initiative Symposium will explore the power of connection in enhancing professional fulfillment for clinicians and healthcare teams, this year under the theme “The Power of We.” Hear from Dr. Shlomit Schall, Houston Methodist Physician Organization president and CEO and chief physician executive, and Dr. J. Bryan Sexton, director of the Duke Center for Advancement and Well-being Science. Stick around for a networking happy hour.

This event is Friday, Oct. 3, from 8:30 a.m.-4:30 p.m. at the InterContinental Houston. Find more information here.

Oct. 6-10 — Surgical Technology & Robotic Surgery Summit (STaRS)

Surgeons, engineers, researchers and innovators can explore the latest advancements in surgical robotics, imaging and AI-integrated technologies at this year’s Surgical Technology & Robotic Surgery Summit. They can also take in the inaugural Surgical Technology & Robotic Surgery Innovator Competition. The summit will feature live demonstrations, interactive panels and cutting-edge research.

This event begins Monday, Oct. 6, at MITIE at The Bookout Center. Find more information here.

Oct. 7 — SUPERGirlsInSTEM Summit: The Intersection of AI & Workforce

The SUPERGirls SHINE Foundation presents its SUPERGirlsInSTEM Summit, where attendees can take part in open discussions, networking and workshops while learning about AI skills that can advance college studies and entry into the workforce.

This event is Tuesday, Oct. 7, from 9 a.m.-1 p.m. at the Ion. Find more information here.

Oct. 7 — Future of Health Care: Thought Leader Series

Hear from Rice University President Reginald DesRoches, and Kristen Doyle, CEO of the Cancer Prevention and Research Institute of Texas, at the Greater Houston Partnership’s Future of Health Care: Thought Leader Series. The expert panel will discuss key topics, including the proposed Dementia Prevention and Research Institute of Texas (DPRIT), Rice's Momentous strategic plan and "critical role of public health systems and cross-sector partnerships in advancing access, equity, and workforce readiness."

This event is Tuesday, Oct. 7, from 9-10:15 a.m. at The Partnership Tower. Find more information here.

Oct 7-9 — Tejano Tech Summit Week

LSA Global will present its fourth annual Tejano Tech Summit Week. The week will feature happy hours, networking opportunities and a founders dinner, along with talks from Mariela Salas, co-founder and partner of Alma Fund; Latina in Tech Houston, Blue People, The Magnolia Fund and others.

This event starts on Tuesday, Oct. 7, with most events taking place at the Ion. Find more information here.

Oct. 8 — Digital Health Institute Launch event

Celebrate the launch of the Houston Methodist-Rice Digital Health Institute, which aims to translate “innovative ideas into scalable solutions” with a focus on engineering, digital health and artificial intelligence. The event will feature presentations from Houston Methodist clinical researchers and Rice University faculty, a startup and industry panel and a venture capital investment panel.

This event is Wednesday, Oct. 8, from 8 a.m.-6:30 p.m. at Rice University's Duncan Hall - McMurtry Hall. Find more information here.

Oct. 8 — Founders Live Houston

Founders Live Houston returns this month with its happy hour pitch event. The global competition will select five Texas founders to present 99-second pitches and participate in a four-minute audience Q&A. Voters decide the winner.

This event is Thursday, Oct. 8, from 6-8 p.m. at the Ion. Find more information here.

Oct. 14 — NASA Stories at the Ion

Dina Contella, deputy manager of NASA’s International Space Station Program, will speak at this month's NASA Stories event. Contella will share insights from her career overseeing International Space Station operations, shaping Artemis missions and guiding real-time decisions in Mission Control.

This event is Tuesday, Oct. 14, from 8:30-10:30 a.m. at the Ion. Find more information here.

Oct. 16 — Impact Hub Houston Celebrates 7 Years in Community + Open Project Night

Celebrate seven years of Impact Hub Houston with a hands-on learning experience focused on hosting. The organization will share the tools, practices and hosting frameworks that have helped it build community and support local changemakers since it launched in 2018. Afterward, participate in Impact Hub's signature Open Project Night, where developers can come together to work on solutions for some of Houston’s most pressing issues.

These events are on Thursday, Oct. 16, at the Ion. The anniversary party is from 2-5 p.m. and Open Project Night begins at 5:30 p.m. Find more information here and here.

Oct. 16 — Future of Global Energy presented by Shell

Industry leaders, academia, and government will "explore the forces shaping the future of energy" at the Greater Houston Partnership's fifth annual Future of Global Energy Conference. Andy Karsner, chief strategist for energy and innovation at X, Alphabet’s Moonshot Factory, and a former U.S. Assistant Secretary of Energy, will present the keynote address. Speakers from companies Fervo Energy, S&P Global, Bechtel and others will also be featured on panels and in fireside chats. The event will culminate in Houston's first National Labs Day, where attendees can engage with leaders and technology specialists from Argonne National Laboratory, Brookhaven National Laboratory and other institutions.

This event is Thursday, Oct. 16, from 9 a.m.-3:30 p.m. Find more information here.

Oct. 23 — NASA Tech Talks

Every fourth Thursday of the month, NASA experts, including longtime engineer Montgomery Goforth, present on technology development challenges NASA’s Johnson Space Center and the larger aerospace community are facing and how they can be leveraged by Houston’s innovation community. Stick around after for drinks and networking at Second Draught.

This event is Thursday, Oct. 23, from 6-7 p.m. at the Ion. Find more information here.

Oct. 25 — Ion Family Tech Festival

The Ion and partners will present the first-ever Ion Family Tech Fest this month, where families can participate in hands-on STEAM experiences.

This event is Saturday, Oct. 25, from 10 a.m.-1 p.m. at the Ion. Find more information here.

Abbott highlights Texas AI boom, with Houston projects on the horizon

AI investments are booming in Texas, Gov. Greg Abbott says. And Houston is poised to benefit from this surge.

At a recent Texas Economic Development Corp. gathering in the Dallas-Fort Worth area, Abbott said AI projects on the horizon in the Lone Star State would be bigger than the $500 billion multistate Project Stargate, according to the Dallas Business Journal. So far, Stargate includes three AI data centers in Texas.

Stargate, a new partnership among OpenAI, Oracle, Softbank, and the federal government, is building AI infrastructure around the country. The project’s first data center is in Abilene, and the center’s second phase is underway. Once the second phase is finished, the 875-acre site will host eight buildings totaling about 4 million square feet with a power capacity of 1.2 gigawatts. An additional 600 megawatts of capacity might be added later.

On Sept. 23, Stargate announced the development of another five AI data centers in the U.S., including a new facility in Shackelford County, Texas, near Abilene. That facility is likely a roughly $25 billion, 1.4-gigawatt AI data center that Vantage Data Centers is building on a 1,200-acre site in Shackelford County.

Another will be in Milam County, between Waco and Austin. In conjunction with Stargate, OpenAI plans to occupy the more than $3 billion center, which will be situated on a nearly 600-acre site, the Austin Business Journal reported. OpenAI has teamed up with Softbank-backed SB Energy Global to build the facility.

Abbott said several unannounced AI projects in Texas — namely, data centers — will be larger than Stargate.

“Bottom line is ... when you look at diversification, the hottest thing going on right now is artificial intelligence,” Abbott said.

The Houston area almost certainly stands to attract some of the projects teased by the governor.

In Houston, Taiwanese tech manufacturer Foxconn already is investing $450 million to make AI servers at the 100-acre Fairbanks Logistics Park, which Foxconn recently purchased for a reported $142 million. The park features four industrial buildings totaling one million square feet. It appears Foxconn will manufacture the servers for Apple and Nvidia, both of which have announced they’ll open server factories in Houston.

The Foxconn, Apple, and Nvidia initiatives are high-profile examples of Houston’s ascent in the AI economy. A report released in July by the Brookings Institution identified Houston as one of the country’s 28 “star” hubs for AI.

The Greater Houston Partnership says the Houston area is undergoing an "AI-driven data revolution."

“As Houston rapidly evolves into a hub for AI, cloud computing, and data infrastructure, the city is experiencing a surge in data center investments driven by its unique position at the intersection of energy, technology, and innovation,” the partnership says.

Ion expansion, Eli Lilly factory, and more Houston innovation news to know

Trending News

Editor's note: We're looking back at the top Houston innovation news for the second half of September. Catch up on the latest from the Ion District, Oxy, Eli Lilly, and more. Here are the five most-read InnovationMap stories from September 15-30:

1. Houston's Ion District to expand with new research and tech space, The Arc

The Arc will feature office and lab space, a gym, an amenity lounge, conference and meeting spaces, outdoor plazas and more. Rendering by Neoscape. Courtesy HKS.

Houston's Ion District is set to expand with the addition of a nearly 200,000-square-foot research and technology facility, The Arc at the Ion District. Rice Real Estate Company and Lincoln Property Company are expected to break ground on the state-of-the-art facility in Q2 2026 with a completion target set for Q1 2028.

Rice University, the new facility's lead tenant, will occupy almost 30,000 square feet of office and lab space in The Arc, which will share a plaza with the Ion and is intended to "extend the district’s success as a hub for innovative ideas and collaboration." Continue reading.

2. Eli Lilly to build $6.5B pharmaceutical factory at Generation Park

Eli Lilly is expected to bring a $6.5 billion manufacturing facility to Houston by 2030. Rendering courtesy Greater Houston Partnership.

Pharmaceutical giant Eli Lilly and Co. plans to build a $6.5 billion manufacturing plant at Houston’s Generation Park. More than 300 locations in the U.S. competed for the factory.

The Houston site will be the first major pharmaceutical manufacturing plant in Texas, according to the Greater Houston Partnership. Lilly said it plans to hire 615 full-time workers for the 236-acre plant, including engineers, scientists and lab technicians. The company will collaborate with local colleges and universities to help build its talent pipeline. Continue reading.

3. Oxy's $1.3B Texas carbon capture facility on track to​ launch this year

Vicki Hollub, president and CEO of Occidental, said the company's Stratos DAC project is on track to begin capturing CO2 later this year. Photo via 1pointfive.com

Houston-based Occidental Petroleum is gearing up to start removing CO2 from the atmosphere at its $1.3 billion direct air capture (DAC) project in the Midland-Odessa area.

Vicki Hollub, president and CEO of Occidental, said the Stratos project — being developed by carbon capture and sequestration subsidiary 1PointFive — is on track to begin capturing CO2 later this year. Continue reading.

4. Houston autonomous trucking co. completes first test run without human intervention

Bot Auto completed its first test run without human assistance in Houston. Photo courtesy Bot Auto.

Houston-based Bot Auto, an autonomous trucking company, has completed its first test run without human assistance. Bot Auto conducted the test in Houston.

“The truck operated seamlessly within its defined operational domain with no one in the cab or remote assistance, navigating real-world traffic conditions,” the company said . “The run was executed at sunset, successfully navigating day and night operations.” Continue reading.

5. Houston team develops low-cost device to treat infants with life-threatening birth defect

SimpleSilo, created at Rice360, offers a low-cost, easy-to-source solution for infants born with gastroschisis. Photo courtesy Rice University

A team of engineers and pediatric surgeons led by Rice University’s Rice360 Institute for Global Health Technologies has developed a cost-effective treatment for infants born with gastroschisis, a congenital condition in which intestines and other organs are developed outside of the body.

The condition can be life-threatening in economically disadvantaged regions without access to equipment.

The Rice-developed device, known as SimpleSilo, is “simple, low-cost and locally manufacturable,” according to the university. It consists of a saline bag, oxygen tubing and a commercially available heat sealer, while mimicking the function of commercial silo bags, which are used in high-income countries to protect exposed organs and gently return them into the abdominal cavity gradually. Continue reading.

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