The Texas Medical Center's ACT program is making sure the most-promising cancer research makes it to its life-saving commercialization stage. Photo via tmc.edu

How do you bring promising cancer research to the masses? TMC Innovation's Accelerator for Cancer Therapeutics was established with that question in mind.

Funded by a $5 million grant from CPRIT, or the Cancer Prevention and Research Institute of Texas, in 2019 and in collaboration with the Gulf Coast Consortia and the University of Texas Medical Branch, the first cohort began their intensive work in 2021. The deadline to join the next cohort is October 13.

Since its inception, ACT has seen the forming of 19 companies — two of which have been awarded CPRIT seed grants, along with four in contention for one this year — as well as $92 million in dilutive funding and $10 million in non-dilutive funding.

“We’ve recruited investigators and companies from the breadth and width of the state of Texas, so all the way from Lubbock to Galveston from Dallas to the Rio Grande Valley,” Ahmed AlRawi, program manager, tells InnovationMap. “We've had an amazing set of investigators who have gone through the program — 56 teams to be precise.”

AlRawi says that the first pillar of the program is education. To that end, the cohort works with entrepreneurs in residence like Michael Torres. Best known as the co-founder of ReCode Therapeutics, Torres says that one of his greatest passions lies in translating science into medicines. ReCode is a genetic medicines company that is currently clinical-stage. It’s raised more than $300 million in the last two years, certainly something to which scientist-entrepreneurs earlier in their careers would aspire.

A longtime resident of Dallas, Torres moved his family to Houston last year, calling it “the place to be for cancer startups in Texas.”

Initially, says Torres, Houston wasn’t on his radar. But thanks to a call from ACT external advisor Dan Hargrove, Torres realized that the city might be a fit for him and his goals.

“I wanted to find a project that I could help support, sort of take my experience as a cofounder and help guide the next great startup within the ecosystem,” he says.

Torres and AlRawi agree that the biggest successes to come out of ACT so far include March Biosciences, a company from the first cohort, which is focused on developing CAR-T cell strategies to help combat hematological cancers; CPRIT fundee, OmniNano Pharmaceuticals, which uses patented nanotechnology to co-deliver a pair of therapeutical agents to solid tumors; and the latest, CrossBridge Bio.

Part of the most recent cohort, Torres has joined Drs. Kyoji Tsuchikama and Zhiqiang An as the last company’s CEO. To that end, he’s partnered with the world-class researchers out of UT Health Houston to build a next-generation antibody drug conjugate company that he believes will produce “better and safer and more effective drugs than what's currently on the market today.”

All the more reason that Torres he’s glad to have moved to Houston at what he calls “a really exciting time.” He’s thankful for the Texas Medical Center and the relationships it fosters. “We're all sort of aligning on creating a sustainable biotech ecosystem,” he says. And the next big cancer fighting company may well emerge from ACT.

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What to know about the new emission inspection to register your car in Texas

seeing green

Texas vehicle owners no longer need to obtain a safety inspection prior to vehicle registration. House Bill 3297, which went into effect January 1 and passed during the 88th Legislature in 2023, eliminates the safety inspection program for non-commercial vehicles.

Under the new law, the $7.50 fee that drivers had to pay as a safety inspection fee has not gone away. It now appears on your registration notice under a new name: "Inspection Program Replacement Fee."

This name change comes courtesy of the legislature, who want to keep collecting this fee because the funds go to state programs such as construction and expansion of state highways — funds they previously collected from the Safety Inspection Fee.

And while the safety inspection is gone, state law will still require that drivers in 17 counties must pass an "emission inspection" on vehicles that are 2 to 24 years old, in order to get your vehicle registered.

But what does an "emissions inspection" mean?

The Texas Department of Public Safety (DPS) details the following changes:

Safety inspection out, emissions testing in
Until December 31, 2024, safety inspections were required for vehicle registration in all 254 counties. Since January 1, 2025, noncommercial vehicles in Texas are no longer be required to have an annual safety inspection. Instead, vehicles have to get an emissions inspection on gasoline-powered vehicles that are 2 to 24 years old.

What is no longer going to be "inspected"?
Texas Transportation Code §548.051 specifies the list of old-school inspection items which will no longer be checked. Moving forward, they will no longer be checking: tires, wheel assembly, safety guards, safety flaps, brakes, steering, lighting, horns, mirrors, windshield wipers, sunscreening devices, and front seat belts in vehicles on which seat belt anchorages were part of the manufacturer's original equipment.

What still is inspected are listed as "Items 12–15": exhaust system, exhaust emissions system, fuel tank cap, and emissions control equipment. These are now part of the emissions inspection process in 17 counties.

Those 17 counties where this is relevant include:

  • DFW: Collin, Dallas, Denton, Ellis, Johnson, Kaufman, Parker, Rockwall, and Tarrant
  • Houston: Brazoria, Fort Bend, Galveston, Harris, and Montgomery
  • Austin: Travis and Williamson
  • El Paso County

Beginning on November 1, 2026, emissions inspections will be required for vehicles registered in Bexar County.

Where will emissions inspections be obtained?
Emissions inspections can be obtained at DPS-certified vehicle inspection stations in the 17 emissions counties. These are the exact same inspection locations we've been going to all along, when it was called a safety inspection. Emissions inspections are not available in the other 237 Texas counties.

DPS offers an inspection station locator online.

What is the estimated cost of an emissions inspection?
Vehicle owners are required to pay an emissions inspection fee of $2.50 annually to the Texas Department of Motor Vehicles (TxDMV) at the time of registration. The actual fee you'll pay at the inspection station (as listed on TCEQ’s website) will be $25.50. Just like the former "safety inspection" fee.

In short: There is little that's changing about the entire inspection process, except they won't bother making you honk your horn.

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This article originally ran on CultureMap.

Houston space tech co. revises timeline for commercial space station development with NASA partnership

new game plan

Houston-based Axiom Space is accelerating its development of a commercial space station.

NASA awarded Axiom a contract in January 2020 to develop a space station for commercial use. Initially, the station was supposed to be attached to the International Space Station. Later, it was supposed to become a free-flying space station in low-earth orbit before retirement of the current space station in 2030.

In coordination with NASA, Axiom Space has modified the plan.

Initially, Axiom planned to attach its first module, Habitat 1, to the space station, followed by three additional modules. Under the new scenario, the payload, power, and thermal modules will be launched first. This will enable the modules to join the current space station as early as 2028, becoming a free-flying station called Axiom Station.

“The International Space Station has provided a one-of-a-kind scientific platform for nearly 25 years,” says Dana Weigel, manager of the International Space Station program at NASA’s Johnson Space Center.

“As we approach the end of [the] space station’s operational life," she continues, "it’s critically important that we look to the future of [low-earth orbit] and support these follow-on destinations to ensure we continue NASA’s presence in microgravity, which began through the International Space Station.”

In free flight, Axiom will continue assembling the commercial destination, adding the Habitat 1 module, an airlock, the Habitat 2 module, and a research and manufacturing lab.

“We were ready to answer the call when NASA asked us to relook at our space station development plan,” Mark Greeley, Axiom Space COO and Axiom Station program manager, says in a statement from Axiom. “Our ongoing assessment of the assembly sequence revealed opportunities for flexibility and enhancements. With the International Space Station needing to protect for the ability to accommodate a deorbit vehicle on station, we were able to accelerate this work to support the program’s requirements.

“NASA has been extremely collaborative and supportive of the new plan as it addresses its deorbit operational concerns and preserves critical capabilities currently utilized on the International Space Station,” he adds. “This revised approach not only aligns with U.S. objectives but also delivers immediate value for our customers and investors.”

The Axiom's Payload Power Thermal Module primary structure is being constructed by Thales Alenia Space in Turin, Italy, and then moved to Houston by fall 2025, where the rest of the internal structure and systems will be integrated at Axiom Space facilities.

“Working with leading experts like Thales Alenia, who have a proven record in module development and a strong relationship with NASA, is integral to our operations and vision," Tejpaul Bhatia, Axiom Space chief revenue officer, says.

“By engaging and integrating with a network of partners from around the world, we access cutting-edge technologies and innovative solutions that enhance our capabilities and supply chain,” Bhatia adds. “Our customer base is truly global, including governments, private entities, and research institutions. This diversity enables us to meet a wide range of needs and reinforces our belief that space exploration is a collective endeavor for the benefit of all of humanity.”

Axiom has revised its plan for its commercial space station. Image via Axiom