This West Coast used car sales platform is en route to Texas. Courtesy of TRED

A Seattle-based online car marketplace has all engines revving for Texas as the company plans its Lone Star State expansion.

TRED announced plans to expand into major Texas cities including, Houston, Dallas, Austin, and San Antonio. The startup will be live in Dallas at the end of this month, followed by the rest of the state in February.

"We very excited about Texas," Grant Feek, co-founder of Tred, tells InnovationMap.

Feek describes the company as a peer-to-peer marketplace for selling and buying used vehicles that offers sellers a thinner transaction margin and buyers a lower price point.

"[We're] combining the best of the dealer experience with the best of the market experience," said Feek.

Feek says that TRED offers the low chance of fraud of a dealership and the value of a private market.

"We are the only ones that allow you to work directly with your counter party," Feek tells InnovationMap. "There's literally no middle man."

TRED handles all the paperwork — from financing to warranties — so that buyers don't have to step foot in a DMV. The company posts their real-time performance online on the "How Tred Stacks Up" page to show how the company compares to other used car marketplaces.

"We built a platform for people that really want value," Feek says. "With the push of a button they can list it in 20 different places"

TRED services will launch in Houston next month, but the company will not have any initial employees on the ground in Texas, as Feek explains that TRED's model is focused on removing employee involvement from auto sales, which, according to Feek, is strategic. TRED is all about getting out of the way of peer-to-peer sales.

The company set their eyes on Houston due to the large population and car market. Feek tells InnovationMap that TRED will also expand into Florida in late 2019.

"It's no secret that a lot of people live in California, Texas, and Florida," says Feek, "we've always had our eyes on these states."

The idea for TRED came about in 2011. Feek says that many of his peers from Harvard, from which he received his MBA in 2009, had started their own companies and he had an interest in the automotive space. He thought that the process buying and selling cars should be simpler.

Feek was able to raise $50,000 of initial funding in New York City and the company's growth was supported by Techstars, a seed accelerator, before moving to their current headquarters of Seattle, Feek says.

"The original business model was a test drive delivery service," said Feek. "In 2015, the company in its current form really started."

Feek founded TRED alongside John Wehr in 2013, when the company launched. He shares that he now oversees the online marketplace with CTO Andrew Crowell.

Feek says the company is working on product enhancements and expanding the services TRED offers. Additional plans include growth into new and existing markets and expanding the number of partners TRED operates with. Feek mentions current partnerships with FedEx, numerous banks and credit unions for financing, Pep Boys, and Firestone.

As of January 2019, TRED is currently available in Seattle; Portland, Oregan; the greater San Francisco Bay area; the greater Los Angeles area; and the greater San Diego area.

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Rice University lands $18M to revolutionize lymphatic disease detection

fresh funding

An arm of the U.S. Department of Health and Human Services has awarded $18 million to scientists at Rice University for research that has the potential to revolutionize how lymphatic diseases are detected and help increase survivability.

The lymphatic system is the network of vessels all over the body that help eliminate waste, absorb fat and maintain fluid balance. Diseases in this system are often difficult to detect early due to the small size of the vessels and the invasiveness of biopsy testing. Though survival rates of lymph disease have skyrocketed in the United States over the last five years, it still claims around 200,000 people in the country annually.

Early detection of complex lymphatic anomalies (CLAs) and lymphedema is essential in increasing successful treatment rates. That’s where Rice University’s SynthX Center, directed by Han Xiao and Lei Li, an assistant professor of electrical and computer engineering, comes in.

Aided by researchers from Texas Children’s Hospital, Baylor College of Medicine, the University of Texas at Dallas and the University of Texas Southwestern Medical Center, the center is pioneering two technologies: the Visual Imaging System for Tracing and Analyzing Lymphatics with Photoacoustics (VISTA-LYMPH) and Digital Plasmonic Nanobubble Detection for Protein (DIAMOND-P).

Simply put, VISTA-LYMPH uses photoacoustic tomography (PAT), a combination of light and sound, to more accurately map the tiny vessels of the lymphatic system. The process is more effective than diagnostic tools that use only light or sound, independent of one another. The research award is through the Advanced Research Projects Agency for Health (ARPA-H) Lymphatic Imaging, Genomics and pHenotyping Technologies (LIGHT) program, part of the U.S. HHS, which saw the potential of VISTA-LYMPH in animal tests that produced finely detailed diagnostic maps.

“Thanks to ARPA-H’s award, we will build the most advanced PAT system to image the body’s lymphatic network with unprecedented resolution and speed, enabling earlier and more accurate diagnosis,” Li said in a news release.

Meanwhile, DIAMOND-P could replace the older, less exact immunoassay. It uses laser-heated vapors of plasmonic nanoparticles to detect viruses without having to separate or amplify, and at room temperature, greatly simplifying the process. This is an important part of greater diagnosis because even with VISTA-LYMPH’s greater imaging accuracy, many lymphatic diseases still do not appear. Detecting biological markers is still necessary.

According to Rice, the efforts will help address lymphatic disorders, including Gorham-Stout disease, kaposiform lymphangiomatosis and generalized lymphatic anomaly. They also could help manage conditions associated with lymphatic dysfunction, including cancer metastasis, cardiovascular disease and neurodegeneration.

“By validating VISTA-LYMPH and DIAMOND-P in both preclinical and clinical settings, the team aims to establish a comprehensive diagnostic pipeline for lymphatic diseases and potentially beyond,” Xiao added in the release.

The ARPA-H award funds the project for up to five years.

Houston doctor wins NIH grant to test virtual reality for ICU delirium

Virtual healing

Think of it like a reverse version of The Matrix. A person wakes up in a hospital bed and gets plugged into a virtual reality game world in order to heal.

While it may sound far-fetched, Dr. Hina Faisal, a Houston Methodist critical care specialist in the Department of Surgery, was recently awarded a $242,000 grant from the National Institute of Health to test the effects of VR games on patients coming out of major surgery in the intensive care unit (ICU).

The five-year study will focus on older patients using mental stimulation techniques to reduce incidences of delirium. The award comes courtesy of the National Institute on Aging K76 Paul B. Beeson Emerging Leaders Career Development Award in Aging.

“As the population of older adults continues to grow, the need for effective, scalable interventions to prevent postoperative complications like delirium is more important than ever,” Faisal said in a news release.

ICU delirium is a serious condition that can lead to major complications and even death. Roughly 87 percent of patients who undergo major surgery involving intubation will experience some form of delirium coming out of anesthesia. Causes can range from infection to drug reactions. While many cases are mild, prolonged ICU delirium may prevent a patient from following medical advice or even cause them to hurt themselves.

Using VR games to treat delirium is a rapidly emerging and exciting branch of medicine. Studies show that VR games can help promote mental activity, memory and cognitive function. However, the full benefits are currently unknown as studies have been hampered by small patient populations.

Faisal believes that half of all ICU delirium cases are preventable through VR treatment. Currently, a general lack of knowledge and resources has been holding back the advancement of the treatment.

Hopefully, the work of Faisal in one of the busiest medical cities in the world can alleviate that problem as she spends the next half-decade plugging patients into games to aid in their healing.